SG11201400999VA - Recombinant nanoparticle rsv f vaccine for respiratory syncytial virus - Google Patents
Recombinant nanoparticle rsv f vaccine for respiratory syncytial virusInfo
- Publication number
- SG11201400999VA SG11201400999VA SG11201400999VA SG11201400999VA SG11201400999VA SG 11201400999V A SG11201400999V A SG 11201400999VA SG 11201400999V A SG11201400999V A SG 11201400999VA SG 11201400999V A SG11201400999V A SG 11201400999VA SG 11201400999V A SG11201400999V A SG 11201400999VA
- Authority
- SG
- Singapore
- Prior art keywords
- rsv
- vaccine
- respiratory syncytial
- syncytial virus
- nanoparticle
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/08—RNA viruses
- C07K14/115—Paramyxoviridae, e.g. parainfluenza virus
- C07K14/135—Respiratory syncytial virus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18522—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18534—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161542040P | 2011-09-30 | 2011-09-30 | |
| US201161542721P | 2011-10-03 | 2011-10-03 | |
| US201261611834P | 2012-03-16 | 2012-03-16 | |
| US201261614286P | 2012-03-22 | 2012-03-22 | |
| PCT/US2012/057546 WO2013049342A1 (en) | 2011-09-30 | 2012-09-27 | Recombinant nanoparticle rsv f vaccine for respiratory syncytial virus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201400999VA true SG11201400999VA (en) | 2014-07-30 |
Family
ID=47996397
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201602434UA SG10201602434UA (en) | 2011-09-30 | 2012-09-27 | Recombinant nanoparticle rsv f vaccine for respiratory syncytial virus |
| SG11201400999VA SG11201400999VA (en) | 2011-09-30 | 2012-09-27 | Recombinant nanoparticle rsv f vaccine for respiratory syncytial virus |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201602434UA SG10201602434UA (en) | 2011-09-30 | 2012-09-27 | Recombinant nanoparticle rsv f vaccine for respiratory syncytial virus |
Country Status (14)
| Country | Link |
|---|---|
| US (4) | US20130122032A1 (en) |
| EP (1) | EP2760469A4 (en) |
| JP (1) | JP2014530010A (en) |
| KR (1) | KR20140077169A (en) |
| CN (2) | CN105381457A (en) |
| AU (1) | AU2013201495B2 (en) |
| BR (1) | BR112014007616A2 (en) |
| CA (1) | CA2849471A1 (en) |
| HK (1) | HK1222125A1 (en) |
| IL (1) | IL231637A0 (en) |
| MX (1) | MX2014003777A (en) |
| RU (1) | RU2014117068A (en) |
| SG (2) | SG10201602434UA (en) |
| WO (1) | WO2013049342A1 (en) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11446374B2 (en) | 2008-12-09 | 2022-09-20 | Novavax, Inc. | Modified RSV F proteins and methods of their use |
| CN102307591B (en) | 2008-12-09 | 2016-08-03 | 诺瓦瓦克斯股份有限公司 | The RSV F protein modified and using method thereof |
| AU2014251247A1 (en) * | 2013-04-08 | 2015-11-05 | Medimmune, Llc | Vaccine composition and method of use |
| US20150110825A1 (en) * | 2013-09-24 | 2015-04-23 | Massachusetts Institute Of Technology | Self-assembled nanoparticle vaccines |
| CN105087643A (en) * | 2014-04-16 | 2015-11-25 | 中国科学院上海巴斯德研究所 | Method for recombinant expression of human respiratory syncytial virus F1 protein extracellular region, and expression system |
| US10100372B2 (en) | 2014-06-18 | 2018-10-16 | Georgia State University Research Foundation, Inc. | Recombinant RSV reporter virus |
| US9630994B2 (en) | 2014-11-03 | 2017-04-25 | University Of Washington | Polypeptides for use in self-assembling protein nanostructures |
| EP3344290A4 (en) * | 2015-08-31 | 2019-02-27 | Technovax, Inc. | Human respiratory syncytial virus (hrsv) virus-like particles (vlps) based vaccine |
| EP3344288A1 (en) * | 2015-09-02 | 2018-07-11 | Janssen Vaccines & Prevention B.V. | Stabilized viral class i fusion proteins |
| RU2730625C2 (en) | 2015-09-03 | 2020-08-24 | Новавакс, Инк. | Vaccine compositions characterized by improved stability and immunogenicity |
| CN106547635B (en) | 2015-09-18 | 2020-10-09 | 阿里巴巴集团控股有限公司 | Operation retry method and device for operation |
| RU2723039C2 (en) | 2015-12-23 | 2020-06-08 | Пфайзер Инк. | Protein f rsv mutants |
| CN106124767A (en) * | 2016-05-12 | 2016-11-16 | 广州瑞辉生物科技股份有限公司 | Respiratory syncytial virus IgA antibody test strip and detection method thereof |
| EP3518967A4 (en) | 2016-10-03 | 2020-04-29 | University of Massachusetts | Methods for immunizing pre-immune subjects against respiratory syncytial virus (rsv) |
| WO2018170238A2 (en) | 2017-03-15 | 2018-09-20 | Novavax, Inc. | Methods and compositions for inducing immune responses against clostridium difficile |
| US11192926B2 (en) | 2017-04-04 | 2021-12-07 | University Of Washington | Self-assembling protein nanostructures displaying paramyxovirus and/or pneumovirus F proteins and their use |
| CN107050446B (en) * | 2017-04-19 | 2020-08-11 | 武汉博沃生物科技有限公司 | Modified seasonal influenza-RSV combination vaccine and method of making same |
| WO2019063844A1 (en) * | 2017-09-29 | 2019-04-04 | Universiteit Antwerpen | Respiratory syncytial virus vaccination |
| CA3095216A1 (en) | 2018-02-28 | 2019-09-06 | University Of Washington | Self-asssembling nanostructure vaccines |
| KR20210004959A (en) | 2018-03-19 | 2021-01-13 | 노바백스, 인코포레이티드 | Multivalent influenza nanoparticle vaccine |
| WO2020076141A1 (en) * | 2018-10-12 | 2020-04-16 | 에스케이바이오사이언스 주식회사 | Recombinant rsv live vaccine strain and production method therefor |
| US20210401969A1 (en) * | 2018-10-29 | 2021-12-30 | Emory University | Rsv virus-like particles and methods of use thereof |
| KR20200050264A (en) * | 2018-11-01 | 2020-05-11 | 에스케이바이오사이언스(주) | Recombinant RSV F protein and vaccine composition comprising thereof |
| WO2020175660A1 (en) * | 2019-02-28 | 2020-09-03 | Ｋｍバイオロジクス株式会社 | Rsv f/g chimeric vaccine |
| CN110229219B (en) * | 2019-06-21 | 2021-03-30 | 中国科学院武汉病毒研究所 | Preparation method and application of novel respiratory syncytial virus vaccine antigen |
| IL295142A (en) * | 2020-01-27 | 2022-09-01 | Novavax Inc | Coronavirus vaccine formulations |
| US10953089B1 (en) | 2020-01-27 | 2021-03-23 | Novavax, Inc. | Coronavirus vaccine formulations |
| CN113855796B (en) * | 2021-07-30 | 2024-01-26 | 河北医科大学 | Application of BCG vaccine as respiratory syncytial virus inactivated vaccine adjuvant |
| WO2023091766A2 (en) * | 2021-11-19 | 2023-05-25 | RNAimmune, Inc. | Compositions and methods of ribonucleic acid respiratory syncytial virus (rsv) vaccines |
| WO2024050015A1 (en) * | 2022-09-01 | 2024-03-07 | Novavax, Inc. | Downstream process for purification of viral proteins with hydrophobic membrane domain for use in vaccine compositions |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101187955B1 (en) * | 2003-04-25 | 2012-10-08 | 비로노바티브 비브이 | Recombinant parainfluenza virus expression systems and vaccines comprising heterologous antigens derived from metapneumovirus |
| EP2181121A4 (en) * | 2007-03-21 | 2012-07-11 | Id Biomedical Corp Quebec | Chimeric antigens |
| PL2540312T3 (en) * | 2007-07-19 | 2015-10-30 | Novavax Inc | Avian influenza chimeric VLPS |
| DK2222710T3 (en) * | 2007-12-24 | 2016-10-03 | Id Biomedical Corp Quebec | Recombinant RSV antigens. |
| EP2254554A1 (en) * | 2008-02-25 | 2010-12-01 | Novavax, Inc. | Sugar glassified virus like particles (vlps) |
| KR101027159B1 (en) * | 2008-07-28 | 2011-04-05 | 뮤추얼아이피서비스(주) | Apparatus and method for target video detecting |
| CN102307591B (en) * | 2008-12-09 | 2016-08-03 | 诺瓦瓦克斯股份有限公司 | The RSV F protein modified and using method thereof |
| WO2010077712A1 (en) * | 2008-12-09 | 2010-07-08 | Novavax, Inc. | Bovine respiratory syncytial virus virus-like particle (vlps) |
-
2012
- 2012-09-27 CA CA2849471A patent/CA2849471A1/en not_active Abandoned
- 2012-09-27 EP EP12835033.7A patent/EP2760469A4/en not_active Withdrawn
- 2012-09-27 MX MX2014003777A patent/MX2014003777A/en unknown
- 2012-09-27 JP JP2014533316A patent/JP2014530010A/en active Pending
- 2012-09-27 CN CN201510769961.3A patent/CN105381457A/en active Pending
- 2012-09-27 SG SG10201602434UA patent/SG10201602434UA/en unknown
- 2012-09-27 WO PCT/US2012/057546 patent/WO2013049342A1/en active Application Filing
- 2012-09-27 CN CN201280059282.1A patent/CN104080476A/en active Pending
- 2012-09-27 BR BR112014007616A patent/BR112014007616A2/en active Search and Examination
- 2012-09-27 US US13/629,107 patent/US20130122032A1/en not_active Abandoned
- 2012-09-27 KR KR1020147009538A patent/KR20140077169A/en not_active Application Discontinuation
- 2012-09-27 SG SG11201400999VA patent/SG11201400999VA/en unknown
- 2012-09-27 AU AU2013201495A patent/AU2013201495B2/en not_active Ceased
- 2012-09-27 RU RU2014117068/10A patent/RU2014117068A/en not_active Application Discontinuation
-
2014
- 2014-03-20 IL IL231637A patent/IL231637A0/en unknown
-
2015
- 2015-02-27 US US14/634,162 patent/US20150335730A1/en not_active Abandoned
- 2015-02-27 US US14/634,171 patent/US20150306207A1/en not_active Abandoned
-
2016
- 2016-08-31 HK HK16110329.3A patent/HK1222125A1/en unknown
-
2017
- 2017-02-15 US US15/433,759 patent/US20170319682A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20150335730A1 (en) | 2015-11-26 |
| KR20140077169A (en) | 2014-06-23 |
| WO2013049342A1 (en) | 2013-04-04 |
| CN104080476A (en) | 2014-10-01 |
| AU2013201495B2 (en) | 2015-12-03 |
| RU2014117068A (en) | 2015-11-10 |
| EP2760469A4 (en) | 2015-03-18 |
| SG10201602434UA (en) | 2016-05-30 |
| BR112014007616A2 (en) | 2017-04-04 |
| MX2014003777A (en) | 2015-05-15 |
| CN105381457A (en) | 2016-03-09 |
| US20130122032A1 (en) | 2013-05-16 |
| CA2849471A1 (en) | 2013-04-04 |
| EP2760469A1 (en) | 2014-08-06 |
| IL231637A0 (en) | 2014-05-28 |
| US20170319682A1 (en) | 2017-11-09 |
| US20150306207A1 (en) | 2015-10-29 |
| JP2014530010A (en) | 2014-11-17 |
| AU2013201495A1 (en) | 2013-04-18 |
| HK1222125A1 (en) | 2017-06-23 |
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