CN104012657A - Amino acid humanized infant formula milk powder and preparation method thereof - Google Patents
Amino acid humanized infant formula milk powder and preparation method thereof Download PDFInfo
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Abstract
The present invention relates to amino acid humanized infant formula milk powder and a preparation method thereof. The amino acid humanized infant formula milk powder comprises the following materials by a certain weight percent: lactose, demineralised whey powder, vegetable oil, skimmed milk powder, hydrolyzed whey protein, galactooligosaccharides, fructo oligosaccharide, a mineral premix, ARA, casein hydrolysate, whey protein concentrate, soybean phospholipids, DHA, a water-soluble vitamin premix, casein phosphopeptides, lactoferrin, L-tyrosine, nucleotide, a lipid soluble vitamin premix, L-tryptophan, L-methionine and taurine. The present invention also includes a method for preparing the amino acid humanized infant formula milk powder. The present invention can effectively solve the problem of pool protein absorption and digestion effect and the low protein utilization rate of infants during infant period.
Description
Technical field
The present invention relates to a kind of baby formula milk powder and preparation method thereof, relate in particular to seed amino acid breast milk baby formula milk powder and preparation method thereof.
Background technology
Breast milk is that baby grows up and grows the most natural, the safest, most complete natural food.But due to various cause specifics, in global range, the baby at pure breast-feeding to 4 monthly age is less than 35% at present.Baby formula milk powder becomes the optimal substitute food product without the not enough baby of breast milk or breast milk, the food absolutely not in general sense of formula milk now, but maintain the important nutrient source of infants growth and development and quality of life.
Protein is the important nutrient in breast milk, and the nutriment in breast milk why can efficient absorption, and this is inseparable with breast milk proteins absorption easy to digest.For kidney and still immature baby of digestive system, the protein that excessive uptake rate is low does not only have benefit, and may cause burden to kidney.Therefore, the high-quality protein of efficient absorption is most important to infants growth and development, and the quality of lactoprotein is closely related with amino acid composition wherein.Lactoprotein becomes various base units--amino acid through enzyme hydrolysis after taking in vivo, and this is one of human body primary demand to protein just.Breast milk is as the most applicable baby's ultimate food, and its balanced amino acid configuration (being Amino acid profile ratio and content) is that baby absorbs optimal pattern.The amino acid composition of breast milk is neonate, and therefore the particularly key factor of premature neonate nutrient absorption for the amino acid configuration, particularly essential and semi-dispensable amino acid of breast milk substitute, is pressed close to breast milk amino acid composition and can effectively be improved protein adsorption rate.
At present, high-quality protein mainly contains protein hydrolysate, alpha lactalbumin, CPP etc.Protein hydrolysate is by hydrolysis technology, and intact proteins is hydrolyzed into small-molecular peptides chain, and by rejecting stodgy protein part, it is more reasonable that the amino acid ratio of acquisition forms, the protein peptide section of more easily digesting and assimilating.Alpha lactalbumin is a kind of protein meriting attention, and is the fabulous source of essential amino acid and branched-chain amino acid, is also the unique lactalbumin composition that can be combined with metallic element and calcium constituent.In addition, alpha lactalbumin is in amino acid ratio structure aspects, and all closely similar with human milk on functional characteristic, the alpha lactalbumin content that clinical studies show improves newborn Dai Pinzhong can improve baby's the absorptivity to protein, can effectively promote infants growth and development, the tryptophan being wherein rich in has remarkable result to improving infantal sleeping quality.CPP (CPP) is taking bovine casein as raw material, the bioactive polypeptide of tool making by biotechnology.CPP molecule is made up of 20 to thirties amino acid residues, the phosphoric acid silk acyl group existing comprising 4～7 clusters.Lot of experiments proves, CPP can promote absorption and the utilization of human body to divalence mineral nutrients such as calcium, iron, zinc effectively.
Along with wet nurse more and more payes attention to for infant's Dietary Quality, the nutrient formation of breast Dai Pin also has a great development, although babies ' formula milk powder lactalbumin and the casein ratio of current domestic use all reach 60:40, less with application to the research of amino acid composition and albumen absorption aspect.
Summary of the invention
Technical problem to be solved by this invention is, seed amino acid breast milk baby formula milk powder and preparation method thereof is provided, bad to solve infantile period infant proteopepsis assimilation effect, the problem that protein utilization is low.
The technical solution adopted for the present invention to solve the technical problems is:
Essential as follows with semi-dispensable amino acid content and breast milk contrast in the present invention's amino acid breast milk baby formula milk powder:
| Project | Formulation content (g/100g protein) | Breast milk *(g/100g protein) |
| Phenylalanine | 3.9±0.3 | 3.9 |
| Methionine | 1.6±0.3 | 1.6 |
| Isoleucine | 5.7±0.3 | 5.9 |
| Leucine | 9.9±0.3 | 9.7 |
| Lysine | 7.1±0.5 | 6.8 |
| Threonine | 5.0±0.5 | 4.7 |
| Valine | 6.1±0.5 | 6.4 |
| Tryptophan | 1.8±0.3 | 1.8 ** |
| Cystine | 2.1±0.3 | 2.1 ** |
| Histidine | 2.2±0.3 | 2.3 |
| Tyrosine | 4.2±0.3 | 4.2 |
* draw from " modern dairy industry handbook " (China Light Industry Press);
* draws breast milk amino acid average content in international food code CODEX STAN 72-1981 Revision 2007.
The present invention's amino acid breast milk baby formula milk powder, material by following percentage by weight forms: lactose 25-35%, desalted whey powder 22-32%, vegetable oil 20-30%, skimmed milk power 5-20%, hydrolyzing lactoalbumin 2-8%, galactooligosaccharide 1-6%, FOS 1-3%, mineral substance premix 0.8-1.5%, arachidonic acid (ARA) 0.3-1.8%, caseinhydrolysate 0.2-1.5%, alpha lactalbumin content is the WPC 0.2-1.4% of 40-45wt%, soybean lecithin 0.2-1.2%, DHA (DHA) 0.2-1.0%, water soluble vitamin premix 0.1-0.4%, CPP 0.10-0.22%, lactoferrin 0.02-0.1%, TYR 0.02-0.09%, nucleotides 0.018-0.05%, liposoluble vitamin premix 0.01-0.06%, L-Trp 0.01-0.05%, L-Methionine 0.01-0.05%, taurine 0.01-0.04%.
Further, described vegetable oil is mixed vegetable oil.
Further, described mixed vegetable oil is made up of the vegetable oil mixture of following percentage by weight: high oleic sunflower oil (it is 80-85wt% that oleic acid accounts for TFA ratio) 30-40%, soybean oil 25-35%, coconut oil 20-30%, rapeseed oil 10-15%.
Further, described mineral substance premix is made up of the material mixture of following percentage by weight: calcium carbonate 20-35%, potassium chloride 20-30%, magnesium sulfate 15-25%, natrium citricum 10-20%, tricalcium phosphate 5-20%, ferrous sulfate 1.5-3.0%, zinc sulfate 0.78-1.18%, copper sulphate 0.086-0.166%, manganese sulfate 0.01-0.08%, KI 0.008-0.022%, sodium selenite 0.002-0.005%.
Further, described water soluble vitamin premix is made up of the material mixture of following percentage by weight: L-AA sodium 45-60%, Choline Chloride 15-30%, inositol 15-25%, niacinamide 1-5%, D-VB5 calcium 0.6-2%, Bio 0.1-1.0%, cyanocobalamin 0.1-0.8%, thiamine hydrochloride 0.1-0.6%, puridoxine hydrochloride 0.08-0.4%, riboflavin 0.04-0.2%, folic acid 0.01-0.18%.
Further, described liposoluble vitamin premix is made up of the material mixture of following percentage by weight: dl-α-D-α-tocopherol acetate 60-75%, axerophtholum aceticum 15-30%, Vitamin D3 4-12%, phytondione 2-10%.
The preparation method of the present invention's amino acid breast milk baby formula milk powder, comprises the following steps:
(1) batching: the WPC, galactooligosaccharide, FOS, mineral substance premix, caseinhydrolysate, water soluble vitamin premix, the taurine that are 40-45wt% by the skimmed milk power taking by predetermined ratio, desalted whey powder, lactose, hydrolyzing lactoalbumin, alpha lactalbumin content, be dissolved in alleged material gross weight 3.0-4.0 40-55 DEG C of water doubly, after mixing, squeeze into temporary tank I; After being mixed, the vegetable oil taking by predetermined ratio, soybean lecithin and liposoluble vitamin premix squeezes into temporary tank II;
Or, fresh milk is carried out at 70-75 DEG C to the 18-22 pasteurize of second, after then fat being separated, make skim milk; The WPC, galactooligosaccharide, FOS, mineral substance premix, caseinhydrolysate, water soluble vitamin premix, the taurine that are 40-45wt% by the desalted whey powder taking by predetermined ratio, lactose, hydrolyzing lactoalbumin, alpha lactalbumin content add in skim milk, the amount that skim milk used meets the dry rear gained skimmed milk power of spraying equates with the amount of directly adding skimmed milk power by predetermined ratio, squeezes into temporary tank I after mixing; After being mixed, the vegetable oil taking by predetermined ratio, soybean lecithin and liposoluble vitamin premix squeezes into temporary tank II;
(2) mix homogeneous: by the mixing of materials of temporary tank I and temporary tank II, homogeneous in high pressure homogenizer, homogenizing temperature 55-70 DEG C, homogenization pressure 10-20MPa;
(3) sterilization: sterilization 15-25 second at 85-95 DEG C;
(4) concentrated: use double-effect falling film evaporator to concentrate, the first effect vacuum is 30-42kPa, and evaporating temperature is 70-75 DEG C; The second effect vacuum is 60-70kPa, and evaporating temperature is 45-52 DEG C, and it is 15-25 ° of B é that material is concentrated into Baume degrees;
(5) spraying is dry: at pressure 12-20MPa, and EAT 150-190 DEG C, temperature of outgoing air is under 70-90 DEG C of condition, to spray to be dried;
(6) fluidized bed drying is cooling: carry out fluidized bed drying and cooling, controlling water content in material is 2.0-4.0wt%, is cooled to cooling, obtains base-material powder;
(7) batch mixing: adopt three-dimensional dry-mixed machine, the arachidonic acid, DHA, CPP, lactoferrin, nucleotides, TYR, L-Trp, the L-Methionine that take by predetermined ratio carry out after premix, drop into dry-mixed machine together with base-material powder, mixing time 15-20 minute, so that mix;
(8) packaging: adopt vacuum nitrogen or carbon dioxide controlled atmospheric packing.
The present invention is taking breast milk proteins matter and Amino acid profile as source, taking breast milk aminoacid ingredient data as basis, by adding the high-quality protein of the absorptions easy to digest such as hydrolyzing lactoalbumin, caseinhydrolysate, rich alpha-lactoalbumin containing WPC, CPP, adjust amino acid configuration to approaching breast milk level, the amino acid breast milk baby formula milk powder that a kind of protein content is low to obtain, protein bioavailability is high, amino acid configuration more approaches breast milk.
Amino acid breast milk baby formula milk powder of the present invention and preparation method thereof has following characteristics:
(1) first from reducing the angle of protein total content, raising protein bioavailability, exploitation amino acid breast milkization modulation baby formula milk powder;
(2) take the lead in for infants endoprotease activity deficiency, common milk from cows and goats Argine Monohydrochloride forms the feature larger with breast milk difference, carry out lactalbumin and casein content ratio breast milk, the formula taking breast milk Amino acid profile as source adjustment, amino acid ratio more approaches breast milk;
(3) take the lead in proposing protein in milk powder, the comprehensive and systematic humanized formula adjustment of amino acid.
Compared with existing common baby formula milk powder, after infants the present invention's amino acid humanized formula milk, be conducive to improve the utilization ratio of infant to protein, solve the problem of protein utilization rate liver kidney low and that cause because albumen quality is inferior burden.
The present invention's amino acid breast milk baby formula milk powder is particularly suitable for that protease hyposecretion, protein utilization are low, the infants more slowly that grows, and can promote Normal Infants absorb and grow.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described.
Embodiment 1
Essential as follows with semi-dispensable amino acid content and breast milk contrast in the amino acid breast milk baby formula milk powder of the present embodiment.
| Project | Formulation content (g/100g protein) | Breast milk (g/100g protein) |
| Phenylalanine | 3.9 | 3.9 |
| Methionine | 1.6 | 1.6 |
| Isoleucine | 5.7 | 5.9 |
| Leucine | 9.9 | 9.7 |
| Lysine | 7.0 | 6.8 |
| Threonine | 5.1 | 4.7 |
| Valine | 6.1 | 6.4 |
| Tryptophan | 1.8 | 1.8 |
| Cystine | 2.1 | 2.1 |
| Histidine | 2.1 | 2.3 |
| Tyrosine | 4.2 | 4.2 |
The amino acid breast milk baby formula milk powder of the present embodiment, material by following percentage by weight forms: lactose 28.0%, vegetable oil 24.8%, desalted whey powder 24.0%, skimmed milk power 12.0%, hydrolyzing lactoalbumin 3.22%, galactooligosaccharide 1.72%, FOS 1.01%, arachidonic acid (ARA) 1.0%, mineral substance premix 0.98%, DHA (DHA) 0.88%, alpha lactalbumin content is the WPC 0.7% of 43wt%, soybean lecithin 0.62%, caseinhydrolysate 0.51%, water soluble vitamin premix 0.18%, CPP 0.147%, lactoferrin 0.064%, TYR 0.054%, taurine 0.031%, nucleotides 0.025%, L-Trp 0.021%, L-Methionine 0.02%, liposoluble vitamin premix 0.018%.
Described vegetable oil is mixed vegetable oil, is made up of the vegetable oil mixture of following percentage by weight: high oleic sunflower oil (it is 80wt% that oleic acid accounts for TFA ratio) 37.4%, soybean oil 28.2%, coconut oil 22.1%, rapeseed oil 12.3%.
Described mineral substance premix is made up of the material mixture of following percentage by weight: calcium carbonate 29.8%, potassium chloride 24.9%, magnesium sulfate 18.3%, natrium citricum 12.6%, tricalcium phosphate 10.4%, ferrous sulfate 2.8%, zinc sulfate 1.02%, copper sulphate 0.143%, manganese sulfate 0.02%, KI 0.014%, sodium selenite 0.003%.
Described water soluble vitamin premix is made up of the material mixture of following percentage by weight: L-AA sodium 55.4%, Choline Chloride 21.1%, inositol 19.7%, niacinamide 1.64%, D-VB5 calcium 0.99%, Bio 0.38%, cyanocobalamin 0.33%, thiamine hydrochloride 0.14%, puridoxine hydrochloride 0.19%, riboflavin 0.093%, folic acid 0.037%.
Described liposoluble vitamin premix is made up of the material mixture of following percentage by weight: dl-α-D-α-tocopherol acetate 68.9%, axerophtholum aceticum 20.5%, Vitamin D3 6.78%, phytondione 3.82%.
Preparation method, comprises the following steps:
(1) batching: fresh milk is carried out at 72 DEG C to the pasteurize of 20 seconds, make skim milk after then fat being separated; The WPC, galactooligosaccharide, FOS, mineral substance premix, caseinhydrolysate, water soluble vitamin premix, the taurine that are 43wt% by the desalted whey powder taking by predetermined ratio, lactose, hydrolyzing lactoalbumin, alpha lactalbumin content add in skim milk, the amount that skim milk used meets the dry rear gained skimmed milk power of spraying equates with the amount of directly adding skimmed milk power by predetermined ratio, squeezes into temporary tank I after mixing; After being mixed, the vegetable oil taking by predetermined ratio, soybean lecithin and liposoluble vitamin premix squeezes into temporary tank II;
(2) mix homogeneous: by the mixing of materials of temporary tank I and temporary tank II, homogeneous in high pressure homogenizer, 65 DEG C of homogenizing temperatures, homogenization pressure 15MPa;
(3) sterilization: sterilization 18 seconds at 85 DEG C;
(4) concentrated: use double-effect falling film evaporator to concentrate, the first effect vacuum is 39kPa, and evaporating temperature is 72 DEG C; The second effect vacuum is 68kPa, and evaporating temperature is 50 DEG C, and it is 18 ° of B é that material is concentrated into Baume degrees;
(5) spraying is dry: at pressure 16MPa, and 170 DEG C of EATs, temperature of outgoing air is under 85 DEG C of conditions, to spray to be dried;
(6) fluidized bed drying is cooling: carry out fluidized bed drying and cooling, controlling water content in material is 3.0wt%, is cooled to cooling, obtains base-material powder;
(7) batch mixing: adopt three-dimensional dry-mixed machine, the arachidonic acid, DHA, CPP, lactoferrin, nucleotides, TYR, L-Trp, the L-Methionine that take by predetermined ratio carry out after premix, drop into dry-mixed machine together with base-material powder, mixing time 20 minutes, so that mix;
(8) packaging: adopt vacuum pack with nitrogen.
Embodiment 2
Essential as follows with semi-dispensable amino acid content and breast milk contrast in the amino acid breast milk baby formula milk powder of the present embodiment.
| Project | Formulation content (g/100g protein) | Breast milk *(g/100g protein) |
| Phenylalanine | 3.9 | 3.9 |
| Methionine | 1.6 | 1.6 |
| Isoleucine | 5.8 | 5.9 |
| Leucine | 9.8 | 9.7 |
| Lysine | 6.9 | 6.8 |
| Threonine | 5.0 | 4.7 |
| Valine | 6.2 | 6.4 |
| Tryptophan | 1.8 | 1.8 ** |
| Cystine | 2.3 | 2.1 ** |
| Histidine | 2.2 | 2.3 |
| Tyrosine | 4.2 | 4.2 |
The amino acid breast milk baby formula milk powder of the present embodiment, material mixture by following percentage by weight forms: desalted whey powder 28.0%, lactose 26.0%, vegetable oil 25.8%, skimmed milk power 8.0%, hydrolyzing lactoalbumin 4.16%, galactooligosaccharide 1.67%, FOS 1.35%, mineral substance premix 1.07%, caseinhydrolysate 0.82%, arachidonic acid (ARA) 0.8%, soybean lecithin 0.64%, DHA (DHA) 0.62%, alpha lactalbumin content is the WPC 0.5% of 43wt%, water soluble vitamin premix 0.18%, CPP 0.16%, lactoferrin 0.069%, TYR 0.049%, taurine 0.032%, liposoluble vitamin premix 0.022%, L-Trp 0.021%, nucleotides 0.02%, L-Methionine 0.017%.
Described vegetable oil is mixed vegetable oil, is made up of the material mixture of following percentage by weight: high oleic sunflower oil (it is 80wt% that oleic acid accounts for TFA ratio) 36.8%, soybean oil 28.5%, coconut oil 22.3%, rapeseed oil 12.4%.
Described mineral substance premix is made up of the material mixture of following percentage by weight: calcium carbonate 25.8%, potassium chloride 25.6%, magnesium sulfate 18.1%, natrium citricum 15.2%, tricalcium phosphate 11.8%, ferrous sulfate 2.4%, zinc sulfate 0.928%, copper sulphate 0.138%, manganese sulfate 0.018%, KI 0.013%, sodium selenite 0.003%.
Described water soluble vitamin premix is made up of the material mixture of following percentage by weight: L-AA sodium 53.0%, Choline Chloride 21.8%, inositol 19.5%, niacinamide 2.44%, D-VB5 calcium 1.56%, Bio 0.52%, cyanocobalamin 0.44%, thiamine hydrochloride 0.33%, puridoxine hydrochloride 0.27%, riboflavin 0.11%, folic acid 0.03%.
Described liposoluble vitamin premix is made up of the material mixture of following percentage by weight: dl-α-D-α-tocopherol acetate 63.3%, axerophtholum aceticum 26.3%, Vitamin D3 5.88%, phytondione 4.52%.
Preparation method, comprises the following steps:
(1) batching: the WPC, galactooligosaccharide, FOS, mineral substance premix, caseinhydrolysate, water soluble vitamin premix, the taurine that are 43wt% by the skimmed milk power taking by predetermined ratio, desalted whey powder, lactose, hydrolyzing lactoalbumin, alpha lactalbumin content, add in the water of 3 times 45 DEG C of alleged material total amounts, after mixing, squeeze into temporary tank I; After being mixed, the vegetable oil taking by predetermined ratio, soybean lecithin and liposoluble vitamin premix squeezes into temporary tank II;
(2) mix homogeneous: by the mixing of materials of temporary tank I and temporary tank II, homogeneous in high pressure homogenizer, 65 DEG C of homogenizing temperatures, homogenization pressure 15MPa;
(3) sterilization: sterilization 20 seconds at 85 DEG C;
(4) concentrated: use double-effect falling film evaporator to concentrate, the first effect vacuum is 40kPa, and evaporating temperature is 72 DEG C; The second effect vacuum is 68kPa, and evaporating temperature is 52 DEG C, and it is 18 ° of B é that material is concentrated into Baume degrees;
(5) spraying is dry: at pressure 16MPa, and 170 DEG C of EATs, temperature of outgoing air is under 85 DEG C of conditions, to spray to be dried;
(6) fluidized bed drying is cooling: carry out fluidized bed drying and cooling, controlling water content in material is 3.0wt%, is cooled to cooling, obtains base-material powder;
(7) batch mixing: adopt three-dimensional dry-mixed machine, the arachidonic acid, DHA, CPP, lactoferrin, nucleotides, TYR, L-Trp, the L-Methionine that take by predetermined ratio carry out after premix, drop into dry-mixed machine together with base-material powder, mixing time 15 minutes, so that mix;
(8) packaging: adopt carbon dioxide controlled atmospheric packing.
clinical feeding trial:
Below in conjunction with clinical testing, the clinical effectiveness of amino acid breast milk baby formula milk powder of the present invention to infant growth is described.
1, Object Selection
Select 60 neonates or baby as research object.Research object is divided into three groups at random: group 1 is fed common babies ' formula milk powder, as a control group; The amino acid breast milk baby formula milk powder that group 2 is fed embodiment 1, as test group; Group 3 is with breast-feeding.The distributing equilibrium such as research object age, sex, childbirth options, maternal age, mother education level and occupation, income situation between each group, there was no significant difference.
2, the impact of different formulations milk powder and breast-feeding on infants anthropometic
For the body weight in anthropometic index, height, BMI, head circumference, chest measurement five indices, adopt Z scoring assistant analysis, Z=(X-M)/SD=(X-M)/(S*M), wherein X is measured value, M is mean, S is the coefficient of variation, and SD is standard deviation, the age in difference week that mean, the coefficient of variation are announced with reference to WHO, the anthropometic standard at monthly age.While feeding 3 months, the present invention's amino acid breast milk baby formula milk powder nursing group and breast-feeding group infant weight, chest measurement increasing value be significantly higher than common babies ' formula milk powder nursing group (
p< 0.05) (table 1), all the other indices are unknown significance difference between three groups.
Impact on physical growth of infants of table 1 different formulations milk powder and breast-feeding 3 months (
± s)
| Group | Common babies ' formula milk powder nursing group | Amino acid breast milk baby formula milk powder nursing group | Breast-feeding group |
| Weight gain value (g) | 2434.0±700.6 | 3350.0±1012.4 * | 3245.0±881.2 * |
| The body weight Z increasing value of marking | 0.22±1.07 | 1.19±1.06 | 1.08±1.04 |
| Growth in stature value (cm) | 9.81±2.19 | 9.81±2.94 | 9.93±4.04 |
| The height Z increasing value of marking | 0.90±1.14 | 0.41±1.48 | 0.58±1.72 |
| BMI（kg/m 2） | 17.5±1.6 | 18.2±1.7 | 18.4±1.7 |
| BMI Z scoring | 0.47±1.05 | 1.02±1.12 | 1.04±1.18 |
| Head circumference increasing value (cm) | 3.68±1.24 | 4.57±1.84 | 4.67±2.23 |
| Head circumference scoring increasing value | 0.12±1.16 | 0.18±1.17 | 0.36±1.56 |
| Chest measurement increasing value (cm) | 2.60±1.95 | 5.47±3.02 * | 5.24±3.25 * |
| Chest measurement scoring increasing value | 2.51±2.85 | 4.30±3.27 | 5.63±4.73 |
*: there is conspicuousness with common baby formula milk powder group comparing difference,
p< 0.05.
3, the impact of different formulations milk powder and breast-feeding on infants peripheral blood element
The tip blood calcium at 3 the end of month of amino acid breast milk baby formula milk powder nursing group Infants'feeding of the present invention and iron content apparently higher than common babies ' formula milk powder nursing group (
p< 0.05), its excess-three group has no notable difference (table 2).
Impact on baby's peripheral blood element level of table 2 different formulations milk powder and breast-feeding 3 months (
± s)
| Element | Common babies ' formula milk powder nursing group | Amino acid breast milk baby formula milk powder nursing group | Breast-feeding group |
| Calcium | 66.47±13.41 | 73.96±9.22* | 68.31±13.41 |
| Magnesium | 31.98±2.62 | 32.28±4.72 | 33.17±5.72 |
| Iron | 339.79±25.14 | 385.18±27.46* | 342.02±48.70 |
| Zinc | 2.56±0.79 | 3.99±2.86 | 3.90±2.23 |
| Copper | 1.02±0.23 | 1.05±3.04 | 0.99±0.24 |
*: there is conspicuousness with common baby formula milk powder group comparing difference,
p< 0.05.
4, conclusion
Through the nursing of different formulations milk powder and breast milk, by growing, the index analysis such as peripheral blood element detection shows: the present invention's amino acid breast milk baby formula milk powder is fed after 3 months the calcium in infant weight, chest measurement, peripheral blood and iron level apparently higher than common babies ' formula milk powder nursing group.The above results shows: the present invention's amino acid breast milk baby formula milk powder absorbs baby's calcium, iron, and anthropometic has certain facilitation.
Claims (7)
1. a seed amino acid breast milk baby formula milk powder, it is characterized in that, material by following percentage by weight forms: lactose 25-35%, desalted whey powder 22-32%, vegetable oil 20-30%, skimmed milk power 5-20%, hydrolyzing lactoalbumin 2-8%, galactooligosaccharide 1-6%, FOS 1-3%, mineral substance premix 0.8-1.5%, arachidonic acid 0.3-1.8%, caseinhydrolysate 0.2-1.5%, alpha lactalbumin content is the WPC 0.2-1.4% of 40-45wt%, soybean lecithin 0.2-1.2%, DHA 0.2-1.0%, water soluble vitamin premix 0.1-0.4%, CPP 0.10-0.22%, lactoferrin 0.02-0.1%, TYR 0.02-0.09%, nucleotides 0.018-0.05%, liposoluble vitamin premix 0.01-0.06%, L-Trp 0.01-0.05%, L-Methionine 0.01-0.05%, taurine 0.01-0.04%.
2. amino acid breast milk baby formula milk powder according to claim 1, is characterized in that, described vegetable oil is mixed vegetable oil.
3. amino acid breast milk baby formula milk powder according to claim 2, it is characterized in that, described mixed vegetable oil is made up of the vegetable oil mixture of following percentage by weight: high oleic sunflower oil 30-40%, soybean oil 25-35%, coconut oil 20-30%, rapeseed oil 10-15%.
4. amino acid breast milk baby formula milk powder according to claim 1 and 2, it is characterized in that, described mineral substance premix is made up of the material mixture of following percentage by weight: calcium carbonate 20-35%, potassium chloride 20-30%, magnesium sulfate 15-25%, natrium citricum 10-20%, tricalcium phosphate 5-20%, ferrous sulfate 1.5-3.0%, zinc sulfate 0.78-1.18%, copper sulphate 0.086-0.166%, manganese sulfate 0.01-0.08%, KI 0.008-0.022%, sodium selenite 0.002-0.005%.
5. amino acid breast milk baby formula milk powder according to claim 1 and 2, it is characterized in that, described water soluble vitamin premix is made up of the material mixture of following percentage by weight: L-AA sodium 45-60%, Choline Chloride 15-30%, inositol 15-25%, niacinamide 1-5%, D-VB5 calcium 0.6-2%, Bio 0.1-1.0%, cyanocobalamin 0.1-0.8%, thiamine hydrochloride 0.1-0.6%, puridoxine hydrochloride 0.08-0.4%, riboflavin 0.04-0.2%, folic acid 0.01-0.18%.
6. amino acid breast milk baby formula milk powder according to claim 1 and 2, it is characterized in that, described liposoluble vitamin premix is made up of the material mixture of following percentage by weight: dl-α-D-α-tocopherol acetate 60-75%, axerophtholum aceticum 15-30%, Vitamin D3 4-12%, phytondione 2-10%.
7. a preparation method for amino acid breast milk baby formula milk powder as claimed in claim 1, is characterized in that, comprises the following steps:
(1) batching: the WPC, galactooligosaccharide, FOS, mineral substance premix, caseinhydrolysate, water soluble vitamin premix, the taurine that are 40-45wt% by the skimmed milk power taking by predetermined ratio, desalted whey powder, lactose, hydrolyzing lactoalbumin, alpha lactalbumin content, be dissolved in alleged material gross weight 3.0-4.0 40-55 DEG C of water doubly, after mixing, squeeze into temporary tank I; After being mixed, the vegetable oil taking by predetermined ratio, soybean lecithin and liposoluble vitamin premix squeezes into temporary tank II;
Or, fresh milk is carried out at 70-75 DEG C to the 18-22 pasteurize of second, after then fat being separated, make skim milk; The WPC, galactooligosaccharide, FOS, mineral substance premix, caseinhydrolysate, water soluble vitamin premix, the taurine that are 40-45wt% by the desalted whey powder taking by predetermined ratio, lactose, hydrolyzing lactoalbumin, alpha lactalbumin content add in skim milk, the amount that skim milk used meets the dry rear gained skimmed milk power of spraying equates with the amount of directly adding skimmed milk power by predetermined ratio, squeezes into temporary tank I after mixing; After being mixed, the vegetable oil taking by predetermined ratio, soybean lecithin and liposoluble vitamin premix squeezes into temporary tank II;
(2) mix homogeneous: by the mixing of materials of temporary tank I and temporary tank II, homogeneous in high pressure homogenizer, homogenizing temperature 55-70 DEG C, homogenization pressure 10-20MPa;
(3) sterilization: sterilization 15-25 second at 85-95 DEG C;
(4) concentrated: use double-effect falling film evaporator to concentrate, the first effect vacuum is 30-42kPa, and evaporating temperature is 70-75 DEG C; The second effect vacuum is 60-70kPa, and evaporating temperature is 45-52 DEG C, and it is 15-25 ° of B é that material is concentrated into Baume degrees;
(5) spraying is dry: at pressure 12-20MPa, and EAT 150-190 DEG C, temperature of outgoing air is under 70-90 DEG C of condition, to spray to be dried;
(6) fluidized bed drying is cooling: carry out fluidized bed drying and cooling, controlling water content in material is 2.0-4.0wt%, is cooled to cooling, obtains base-material powder;
(7) batch mixing: adopt three-dimensional dry-mixed machine, the arachidonic acid, DHA, CPP, lactoferrin, nucleotides, TYR, L-Trp, the L-Methionine that take by predetermined ratio carry out after premix, drop into dry-mixed machine together with base-material powder, mixing time 15-20 minute, so that mix;
(8) packaging: adopt vacuum nitrogen or carbon dioxide controlled atmospheric packing.
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