CN109874870A - A kind of infant milk powder of simulation breast milk proteins composition and immune function - Google Patents

A kind of infant milk powder of simulation breast milk proteins composition and immune function Download PDF

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Publication number
CN109874870A
CN109874870A CN201910075217.1A CN201910075217A CN109874870A CN 109874870 A CN109874870 A CN 109874870A CN 201910075217 A CN201910075217 A CN 201910075217A CN 109874870 A CN109874870 A CN 109874870A
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powder
parts
immune function
breast milk
infant
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曾荣跃
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Shanghai Howell Nutritional Dairy Co Ltd
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Shanghai Howell Nutritional Dairy Co Ltd
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Abstract

The invention discloses the infant milk powders of a kind of simulation breast milk proteins composition and immune function, it is related to milk powder technical field, it is characterized in that: a kind of infant milk powder of simulation breast milk proteins composition and immune function, the component including following parts by weight: plant fat powder: 44~50 parts;Desalted whey powder: 30~45 parts;Whole-fat milk powder: 3~8 parts;Whey protein concentrate: 0.5~1 part;α-lactalbumin powder: 2~4 parts;Lactose: 1~5 part;Lactoferrin: 0.02~0.1 part;Calcium carbonate: 0.1~0.36 part;Calcium monohydrogen phosphate: 0.1~2 part;Potassium chloride: 0.2~0.6 part;Sodium chloride: 0.1~0.3 part;Compounding minerals: 0.1~0.5 part;Compounding vitamin: 0.1~0.3 part.The present invention passes through the addition of α-lactalbumin and iron albumin, and optimization protein forms to simulate breast milk, improves the content of tryptophan in formula, close to the composition of breast milk proteins matter, is easy to baby's digestion and absorption.

Description

A kind of infant milk powder of simulation breast milk proteins composition and immune function
Technical field
The present invention relates to milk powder technical fields, more specifically, it relates to a kind of simulation breast milk proteins composition and immune function The infant milk powder of energy.
Background technique
Breast milk is the optimal natural nutrition source of infant, however not can be carried out breast-feeding due to personal, Baby formula milk powder is optimal breast milk substitute.Therefore breast milk is also the gold standard of baby formula milk powder research and development, Scientist also constantly studies breast milk nutritional ingredient, pushes the development of baby formula milk powder.Pass through at present and has added The nutrient categories for adding breast milk to contain simulate breast milk nutrition, such as in protein, fat, carbohydrate, minerals, vitamin As far as possible close to breast milk on equal nutriments and quantity.
In the prior art, although milk powder raw material quantity on protein amounts is closer to breast milk, protein composition It is to differ larger with breast milk, causes the effect difference of milk powder and breast milk larger.
Summary of the invention
In view of the deficiencies of the prior art, the present invention intends to provide a kind of simulation breast milk proteins composition and immune The infant milk powder of function optimizes protein composition by the addition of α-lactalbumin and iron albumin to simulate breast milk, raising is matched The content of tryptophan in side is easy to baby's digestion and absorption close to the composition of breast milk proteins matter.
To achieve the above object, the present invention provides the following technical scheme that
A kind of infant milk powder of simulation breast milk proteins composition and immune function, the component including following parts by weight:
Plant fat powder: 44~50 parts;
Desalted whey powder: 30~45 parts;
Whole-fat milk powder: 3~8 parts;
Whey protein concentrate: 0.5~1 part;
α-lactalbumin powder: 2~4 parts;
Lactose: 1~5 part;
Lactoferrin: 0.02~0.1 part;
Calcium carbonate: 0.1~0.36 part;
Calcium monohydrogen phosphate: 0.1~2 part;
Potassium chloride: 0.2~0.6 part;
Sodium chloride: 0.1~0.3 part;
Compounding minerals: 0.1~0.5 part;
Compounding vitamin: 0.1~0.3 part.
By using above-mentioned technical proposal, α-lactalbumin contains a variety of and very similar essential amino acid of baby's demand, Especially tryptophan and cysteine content is higher, and tryptophan can be converted to the important transmitting substance of one of human brain, That is serotonin, and serotonin has the function of neutralizing adrenaline and Prostacyclin, and can improve holding for baby sleep The continuous time;Cysteine is the component part of glutathione (pith of newborn's body antioxidant system), or synthesis The precursor substance of taurine and a component part of bile salt play weight in the development of infant's cerebral nervous system It acts on;Furthermore α-lactalbumin polymer also has the function of anti-infective, promotion Apoptosis, these functions are to protection baby children Youngster's intestinal health is of great significance.
There is a lactoferrin receptor on immunocyte surface, lactoferrin by conjunction with receptor, promote T cell, B cell, The maturation of macrophage and activation, and promote antibody tormation, the immune response of body is adjusted, pathogen remaining in vivo is removed.
The present invention based on breast milk, from the type of protein, the content of each component, must amino acid the several sides of content Protein in formula optimizes, by the cream for adding the α-lactalbumin and clinical test level that reach breast milk level Ferritin, various dimensions are close to breast milk proteins matter.
It further preferably, further include parts by weight in the simulation breast milk proteins composition and the infant milk powder of immune function For 1~4 part of oligofructose.
By using above-mentioned technical proposal, oligofructose is hardly digested and absorbs in human stomach and small enteral, directly Colon is entered by Bifidobacterium, lactic acid bacteria etc. using fermenting, promotes the breeding of colon probiotics, improves intestinal microecology ring Border;Oligofructose belongs to the water-soluble dietary fiber of small molecule quality, and can absorb moisture keeps excrement thinning, and by intestinal flora The short chain fatty acids that fermentation generates, reduce colon pH, can stimulate Colon Movement, to relief of constipation and promote defecation Effect.
It further preferably, further include parts by weight in the simulation breast milk proteins composition and the infant milk powder of immune function For 0.6~0.9 part of casein phosphopeptide.
By using above-mentioned technical proposal, casein phosphopeptide is that a kind of biology generated after casein digests in vivo is lived Property polypeptide, can promote the absorption of calcium ion, and calcium ion can help lymph node cells to activate by changing rouge molecular function And proliferation, and the production quantity of antibody is improved, so that body be helped to understand pathogen;Casein phosphopeptide can also promote animal simultaneously Absorption and utilization to minerals such as iron, zinc, selenium are a kind of good Analyses of High Affinity Binding Peptides, and (α-is milky white with other nutritional ingredients Albumen, oligofructose) collective effect is used to improve the immune functions of Normal Infants.
It further preferably, further include parts by weight in the simulation breast milk proteins composition and the infant milk powder of immune function For 0.01~0.1 part of mixed nucleotides.
By using above-mentioned technical proposal, nucleotide is the important source material of synthesis RNA and DNA in infants, for storing With convey hereditary information, and synthesis ATP raw material, play a significant role in cellular energy metabolism;Nucleotide can speed up Growth, differentiation and the reparation of small intestine cells, increase the blood flow of enteron aisle, can also adjust intestinal flora, play to enteron aisle Benefit effect;In addition, nucleotide can stimulate lymphocyte differentiation and proliferation, can provide to be unable to the lymphocyte of synthesizing ribonucleotide can The nucleotide utilized, so having the function of adjusting immune function.
Further preferably, the mixed nucleotides include cytidylic acid CMP, uridylate UMP, adenine Nucleotide AMP, guanylic acid GMP and inosinic acid IMP.
Further preferably, the plant fat powder includes Canola Oil, maize oil plus coconut oil.
By using above-mentioned technical proposal, Canola Oil can reduce body's cholesterol total amount;Corn oil is more effective Promote baby's eyesight and mental development;Coconut oil contains a large amount of lauric acid, has very strong anti-virus sterilizing effect;Three combination and At plant fat powder, the combination advantage of each component can be given full play to, the growth of power-assisted infantile health.
Further preferably, further include the component of following parts by weight in the raw material components:
DHA and AA:0.5~0.8 part;
Hydrolyzing lactoalbumin: 0.8~1.2 part;
Hydrolysis skimmed milk power: 0.8~1.2 part;
Beta-casein: 0.8~1.2 part;
Milk fat globule membrane protein: 0.4~1.6 part.
By using above-mentioned technical proposal, DHA, docosahexaenoic acid is commonly called as docosapentaenoic acid, is that a kind of pair of human body is very heavy The unsaturated fatty acid wanted belongs to the important member in omega-3 unsaturated fatty acid family.DHA be nervous system cell growth and A kind of main component maintained, is the important composition ingredient of brain and retina, and content is up to 20% in human brain cortex, Proportion is maximum in eye retina, accounts for about 50%, therefore, most important to tire infant intelligence and visual acuity;AA is learned Name eicosatetraenoic acid also known as arachidonic acid, development and intelligence to baby's central nervous system, immune system, retina The raising of power has highly important effect.
Hydrolyzing lactoalbumin is the product of protease hydrolytic whey protein concentrate or lactoalbumin, is applied in milk powder more Absorption easy to digest, it is smaller to stomach burden, more comfortably.
Skimmed milk power is hydrolyzed not only by hydrolyzed whey protein, also part casein is also hydrolyzed, is easier to digest and assimilate, to intestines Stomach burden is smaller, more comfortably.
Beta-casein, optimization product casein composition, beta-casein is the primary structure of breast milk casein, in infant formula Beta-casein is used in milk powder, cow's milk can be made closer to human milk, to reduce the gap of cow milk feeding and breast-feeding, separately Outside, beta-casein is used in infant milk powder, can effectively improve the property easy to digest of integral formula milk powder.
Milk fat globule membrane protein is biological activity protein rich in, rich in newborn phosphatide (sphingomyelin, phosphatidyl Choline, phosphatidylserine etc.), the whey protein concentrate of gangliosides and immune factor, there is high nutritive value, favorably In baby's nervous system development.
In conclusion compared with prior art, the invention has the following advantages:
Canola Oil can reduce body's cholesterol total amount;Corn oil more effectively promotes baby's eyesight and mental development;Coconut palm Seed oil contains a large amount of lauric acid, has very strong anti-virus sterilizing effect;The plant fat powder that three is composed can sufficiently be sent out Wave the combination advantage of each component, the growth of power-assisted infantile health.
This formula, which is added to, is currently known the required nutritional ingredient for being able to satisfy infants growth and development, and additive amount can satisfy baby The normal nutrition demand of youngster, while also having the following characteristics that
(1) optimize the composition of product protein
α-lactalbumin is added, so that its content is reached breast milk level, and add the lactoferrin of clinical test level, optimizes product The composition of protein makes kinds of protein in formula and each component content closer to breast milk, and the required ammonia such as improve tryptophan The content of base acid reaches breast milk level.
(2) material base is provided for the development and perfect in shape and function of infant immunization system
According to research papers, addition nucleotide, oligofructose and casein phosphopeptide reach clinical level, with newborn iron egg White development and perfect in shape and function for infant immunization system provides material base, adjusts immunity of organism.
Specific embodiment
Below with reference to embodiment, the present invention will be described in detail.
Embodiment 1: a kind of infant milk powder of simulation breast milk proteins composition and immune function, the group including following parts by weight Point: 44 parts of plant fat powder, 30 parts of desalted whey powder, 3 parts of whole-fat milk powder, 2 parts of α-lactalbumin powder, 1 part of lactose, lactoferrin 0.02 part, 0.1 part of calcium carbonate, 0.1 part of calcium monohydrogen phosphate, 0.2 part of potassium chloride, 0.1 part of sodium chloride, 0.1 part of minerals of compounding, compounding Vitamin: 0.1~0.3 part.
Wherein, plant fat powder includes Canola Oil, maize oil plus coconut oil, and compounding minerals include biphosphate Potassium, magnesium sulfate, manganese sulfate, potassium sulfate, copper sulphate, zinc sulfate, potassium iodide and sodium selenite;Compounding vitamin include VA, VD, VE、VK1、VB1、VB2、VB6、VB12, VC, niacinamide usp, folic acid, pantothenic acid and biotin.
Embodiment 2-8: it is a kind of simulation breast milk proteins composition and immune function infant milk powder, it is different from embodiment 1 it It is in each component and its corresponding parts by weight are as shown in table 1.
Each component and its parts by weight in 1 embodiment 2-8 of table
Embodiment 9: a kind of infant milk powder of simulation breast milk proteins composition and immune function, the difference with embodiment 1 It is, wherein further including the oligofructose that parts by weight are 1 part.
Embodiment 10: a kind of infant milk powder of simulation breast milk proteins composition and immune function, the difference with embodiment 1 It is, wherein further including the oligofructose that parts by weight are 2.5 parts.
Embodiment 11: a kind of infant milk powder of simulation breast milk proteins composition and immune function, the difference with embodiment 1 It is, wherein further including the oligofructose that parts by weight are 4 parts.
Embodiment 12: it is a kind of simulation breast milk proteins composition and immune function infant milk powder, it is different from embodiment 11 it It is in wherein further including the casein phosphopeptide that parts by weight are 0.6 part.
Embodiment 13: it is a kind of simulation breast milk proteins composition and immune function infant milk powder, it is different from embodiment 11 it It is in wherein further including the casein phosphopeptide that parts by weight are 0.75 part.
Embodiment 14: it is a kind of simulation breast milk proteins composition and immune function infant milk powder, it is different from embodiment 11 it It is in wherein further including the casein phosphopeptide that parts by weight are 0.9 part.
Embodiment 15: it is a kind of simulation breast milk proteins composition and immune function infant milk powder, it is different from embodiment 13 it It is in wherein further including the mixed nucleotides that parts by weight are 0.01 part, wherein mixed nucleotides include cytidylic acid CMP, uridylate UMP, adenylic acid AMP, guanylic acid GMP and inosinic acid IMP.
Embodiment 16: it is a kind of simulation breast milk proteins composition and immune function infant milk powder, it is different from embodiment 13 it It is in wherein further including the mixed nucleotides that parts by weight are 0.05 part, wherein mixed nucleotides include cytidylic acid CMP, uridylate UMP, adenylic acid AMP, guanylic acid GMP and inosinic acid IMP.
Embodiment 17: it is a kind of simulation breast milk proteins composition and immune function infant milk powder, it is different from embodiment 13 it It is in wherein further including the mixed nucleotides that parts by weight are 0.1 part, wherein mixed nucleotides include cytidylic acid CMP, uridylate UMP, adenylic acid AMP, guanylic acid GMP and inosinic acid IMP.
Embodiment 18: a kind of infant milk powder of simulation breast milk proteins composition and immune function, the difference with embodiment 1 It is, wherein further including DHA, AA, the hydrolysis that parts by weight are 0.2,0.3 part, 0.8 part, 0.9 part, 1 part and 0.5 part Lactalbumin, hydrolysis skimmed milk power, beta-casein and milk fat globule membrane protein.
Comparative example 1: a kind of infant milk powder of simulation breast milk proteins composition and immune function, the difference with embodiment 1 It is, the component including following parts by weight: 44 parts of plant fat powder, 30 parts of desalted whey powder, 3 parts of whole-fat milk powder, lactose 1 Part, 0.02 part of lactoferrin, 0.1 part of calcium carbonate, 0.1 part of calcium monohydrogen phosphate, 0.2 part of potassium chloride, 0.1 part of sodium chloride, compounding mineral 0.1 part of matter, compounding vitamin: 0.1~0.3 part.
Wherein, plant fat powder includes Canola Oil, maize oil plus coconut oil, and compounding minerals include biphosphate Potassium, magnesium sulfate, manganese sulfate, potassium sulfate, copper sulphate, zinc sulfate, potassium iodide and sodium selenite;Compounding vitamin include VA, VD, VE、VK1、VB1、VB2、VB6、VB12, VC, niacinamide usp, folic acid, pantothenic acid and biotin.
Comparative example 2: a kind of infant milk powder of simulation breast milk proteins composition and immune function, the difference with embodiment 1 It is, a kind of infant milk powder of simulation breast milk proteins composition and immune function, difference from example 1 is that, including such as The component of lower parts by weight: 44 parts of plant fat powder, 30 parts of desalted whey powder, 3 parts of whole-fat milk powder, 2 parts of α-lactalbumin powder, cream 1 part of sugar, 0.1 part of calcium carbonate, 0.1 part of calcium monohydrogen phosphate, 0.2 part of potassium chloride, 0.1 part of sodium chloride, 0.1 part of minerals of compounding, compounding Vitamin: 0.1~0.3 part.
Wherein, plant fat powder includes Canola Oil, maize oil plus coconut oil, and compounding minerals include biphosphate Potassium, magnesium sulfate, manganese sulfate, potassium sulfate, copper sulphate, zinc sulfate, potassium iodide and sodium selenite;Compounding vitamin include VA, VD, VE、VK1、VB1、VB2、VB6、VB12, VC, niacinamide usp, folic acid, pantothenic acid and biotin.
Comparative example 3: a kind of infant milk powder of simulation breast milk proteins composition and immune function, the difference with embodiment 1 It is, a kind of infant milk powder of simulation breast milk proteins composition and immune function, difference from example 1 is that, including such as The component of lower parts by weight: 44 parts of plant fat powder, 30 parts of desalted whey powder, 3 parts of whole-fat milk powder, 1 part of lactose, calcium carbonate 0.1 Part, 0.1 part of calcium monohydrogen phosphate, 0.2 part of potassium chloride, 0.1 part of sodium chloride, 0.1 part of minerals of compounding, compounding vitamin: 0.1~0.3 Part.
Wherein, plant fat powder includes Canola Oil, maize oil plus coconut oil, and compounding minerals include biphosphate Potassium, magnesium sulfate, manganese sulfate, potassium sulfate, copper sulphate, zinc sulfate, potassium iodide and sodium selenite;Compounding vitamin include VA, VD, VE、VK1、VB1、VB2、VB6、VB12, VC, niacinamide usp, folic acid, pantothenic acid and biotin.
Sensory testing and evaluation: organoleptic test is carried out to 1-18 of the embodiment of the present invention, evaluation criterion is according to " Chinese dairy products Industrial trade specification RHB 204-2004 " infant formula sense organ criticism detailed rules and regulations.
Test result: it is observed that formula milk color made from 1-18 of the embodiment of the present invention is uniform, it is in milk yellow, pale yellow Color, shallow milk yellow and buff, it is glossy, particle uniformly, loose, good fluidity;Sinking time is less than 8s when milk powder is dissolved in water, Brew is good;Lotion after reconstituting has the distinctive natural fragrance of breast milk.
Tracking of products evaluation: according to " baby formula milk powder nutrition, safe tracking evaluation scheme ", to the embodiment of the present invention 1-18 simulation breast milk proteins composition obtained and the infant milk powder commercialized product of immune function are carried out using return visit, tracking evaluation its Nutrition, safety, the corresponding return visit number of each embodiment are 10 people.
It pays a return visit result: the statistical result of return visit being included in table 2 and table 3, by the statistics knot in table 2 and table 3 Fruit is it is found that during the simulation breast milk proteins composition made from edible embodiment 1-18 and the infant milk powder of immune function, Ying Ershen Long and weight is developed normally substantially, and resistance is stronger;Do not occur other adverse reactions such as diarrhea, excessive internal heat, constipation substantially.
The return visit result of the infant milk powder of breast milk proteins composition and immune function is simulated in 2 embodiment 1-8 of table
The return visit result of the infant milk powder of breast milk proteins composition and immune function is simulated in 2 embodiment 9-17 of table
The above is only a preferred embodiment of the present invention, protection scope of the present invention is not limited merely to above-mentioned implementation Example, all technical solutions belonged under thinking of the present invention all belong to the scope of protection of the present invention.It should be pointed out that for the art Those of ordinary skill for, several improvements and modifications without departing from the principles of the present invention, these improvements and modifications It should be regarded as protection scope of the present invention.

Claims (7)

1. a kind of infant milk powder of simulation breast milk proteins composition and immune function, which is characterized in that including following parts by weight Component:
Plant fat powder: 44~50 parts;
Desalted whey powder: 30~45 parts;
Whole-fat milk powder: 3~8 parts;
Whey protein concentrate: 0.5~1 part;
α-lactalbumin powder: 2~4 parts;
Lactose: 1~5 part;
Lactoferrin: 0.02~0.1 part;
Calcium carbonate: 0.1~0.36 part;
Calcium monohydrogen phosphate: 0.1~2 part;
Potassium chloride: 0.2~0.6 part;
Sodium chloride: 0.1~0.3 part;
Compounding minerals: 0.1~0.5 part;
Compounding vitamin: 0.1~0.3 part.
2. the infant milk powder of simulation breast milk proteins composition and immune function according to claim 1, which is characterized in that described It further include the oligofructose that parts by weight are 1~4 part in simulation breast milk proteins composition and the infant milk powder of immune function.
3. the infant milk powder of simulation breast milk proteins composition and immune function according to claim 1, which is characterized in that described It further include the casein phosphoric acid that parts by weight are 0.6~0.9 part in simulation breast milk proteins composition and the infant milk powder of immune function Peptide.
4. the infant milk powder of simulation breast milk proteins composition and immune function according to claim 1, which is characterized in that described It further include the mixing nucleosides that parts by weight are 0.01~0.1 part in simulation breast milk proteins composition and the infant milk powder of immune function Acid.
5. the infant milk powder of simulation breast milk proteins composition and immune function according to claim 4, which is characterized in that described Mixed nucleotides include cytidylic acid CMP, uridylate UMP, adenylic acid AMP, guanylic acid GMP With inosinic acid IMP.
6. the infant milk powder of simulation breast milk proteins composition and immune function according to claim 1, which is characterized in that described Plant fat powder includes Canola Oil, maize oil plus coconut oil.
7. the infant milk powder of simulation breast milk proteins composition and immune function according to claim 1, which is characterized in that also wrap Include the component of following parts by weight:
DHA and AA:0.5~0.8 part;
Hydrolyzing lactoalbumin: 0.8~1.2 part;
Hydrolysis skimmed milk power: 0.8~1.2 part;
β-casein: 0.8~1.2 part;
Milk fat globule membrane protein: 0.4~1.6 part.
CN201910075217.1A 2019-01-25 2019-01-25 A kind of infant milk powder of simulation breast milk proteins composition and immune function Pending CN109874870A (en)

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