CN112998080A - Infant formula milk powder added with yolk phospholipid, soybean phospholipid and milk phospholipid - Google Patents
Infant formula milk powder added with yolk phospholipid, soybean phospholipid and milk phospholipid Download PDFInfo
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- CN112998080A CN112998080A CN202110283180.9A CN202110283180A CN112998080A CN 112998080 A CN112998080 A CN 112998080A CN 202110283180 A CN202110283180 A CN 202110283180A CN 112998080 A CN112998080 A CN 112998080A
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C21/00—Whey; Whey preparations
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C21/00—Whey; Whey preparations
- A23C21/08—Whey; Whey preparations containing other organic additives, e.g. vegetable or animal products
Abstract
The invention belongs to the technical field of formula milk powder, and particularly relates to infant formula milk powder added with yolk phospholipid, soybean phospholipid and milk phospholipid. The feed comprises raw milk or raw goat milk, desalted whey powder, partially hydrolyzed whey protein powder, buttermilk powder, 1, 3-dioleate-2-palmitic triglyceride, soybean oil, olive oil, anhydrous cream, fructo-oligosaccharide powder, galacto-oligosaccharide, compound vitamins, compound minerals, calcium hydrophosphate, calcium carbonate, sodium citrate, potassium chloride, potassium carbonate, tricalcium phosphate, egg yolk phospholipid, soybean phospholipid, choline chloride, L-carnitine, inositol, mono-diglycerol fatty acid ester, DHA powder, ARA powder, vitamin C, lutein and bifidobacterium animalis Bb-12. The invention provides the infant formula milk powder most close to the composition of the breast milk phospholipid by adding and adjusting the proportion of the egg yolk phospholipid, the soybean phospholipid and the milk phospholipid to simulate the composition of the breast milk phospholipid, and provides help for the cognition, the brain development and the like of the infant.
Description
Technical Field
The invention belongs to the technical field of formula milk powder, and particularly relates to infant formula milk powder added with yolk phospholipid, soybean phospholipid and milk phospholipid.
Background
Breast milk is the most ideal food for infants, and breast milk fat is an important component in breast milk, not only is a main source of energy required for the growth and development of infants, but also provides various fat-soluble nutrients. Particularly, breast milk phospholipids include various functional milk phospholipids such as Phosphatidylcholine (PC), Phosphatidylethanolamine (PE), Phosphatidylserine (PS), Phosphatidylinositol (PI), Sphingomyelin (SM), and the like. However, most infant formula foods do not contain breast milk fat, and various vegetable oil formulas are used for simulating the content of breast milk fat and the composition of fatty acid. Although some infant formula milk powder is added with milk fat globule membranes rich in milk phospholipids, the milk fat globule membranes are derived from cow milk or goat milk, and the milk phospholipids are close to the human milk phospholipids to some extent, but have low similarity with the human milk phospholipids.
TABLE 1 milk phospholipid content and ratio of some mammals
The general composition of egg yolk lecithin is: phosphatidylcholine is up to 70%, phosphatidylinositol is only 0.6%. Does not contain: phosphatidic acid, phosphatidylserine, N-acylphosphatidylethanolamine, phosphatidylglycerol. In egg yolk phospholipids, R1 is almost saturated fatty acid, R2 is usually unsaturated fatty acid, and the fatty acid components of egg yolk phospholipids are mostly palmitic acid and oleic acid, and then stearic acid and linoleic acid, and further contain trace amounts of polyunsaturated fatty acids and odd-numbered fatty acids (e.g., heptadecanoic acid) such as arachidonic acid and docosahexaenoic acid, which have been attracting attention in recent years. The general composition of soy phospholipids is: 25-32% of phosphatidylcholine PC (lecithin), 15-22% of phosphatidylethanolamine PE (cephalin), about 15% of phosphatidylinositol PI (inositol phosphatide), about 16% of phosphatidylglycerol SM (sphingomyelin), about 4% of phosphatidic acid PA, and about 8% of other phospholipids. The soybean lecithin R1 and R2 are mixed coordination of saturated acid and unsaturated acid, wherein linoleic acid accounts for about 50 percent, and the soybean lecithin hardly contains fatty acid with more than C20. By adjusting the proportion of soybean phospholipid, yolk phospholipid and milk phospholipid and adding the soybean phospholipid, yolk phospholipid and milk phospholipid into infant formula milk powder in a proper amount, the composition of phospholipid in breast milk can be simulated, and the milk powder is closer to breast milk.
Bifidobacterium Bb-12 (hereinafter abbreviated as Bb-12) belongs to Bifidobacterium animalis strain 12, and is a catalase-negative rod-shaped bacterium. The health-care effects of Bb-12 have been demonstrated in many clinical studies of gastrointestinal health and immune function. Clinical studies have demonstrated that Bb-12 is viable through the gastrointestinal tract and maintains a healthy gastrointestinal flora. Moreover, studies have shown that Bb-12 improves gut function, prevents diarrhea, and reduces the side effects of antibiotic therapy, such as antibiotic-associated diarrhea. In the aspect of immune function, clinical researches show that Bb-12 can improve the resistance of the body to common respiratory tract infection and simultaneously reduce the incidence rate of acute respiratory tract infection.
TABLE 2 results of several clinical studies of Bifidobacterium animalis Bb-12
Disclosure of Invention
The invention aims to solve the technical problem that breast milk is the most ideal food for infants, and even some infant formula milk powder is added with a milk fat globule membrane rich in milk phospholipids, the milk fat globule membrane is derived from cow milk or goat milk, and the milk phospholipids are close to the breast milk phospholipids to a certain extent but have low similarity with the breast milk phospholipids.
In order to solve the problems, the invention provides the infant formula milk powder closest to the composition of the breast milk phospholipid by adding and adjusting the proportion of the egg yolk phospholipid, the soybean phospholipid and the milk phospholipid in the infant formula milk powder to simulate the composition of the breast milk phospholipid, and provides help for the cognition, the brain development and the like of the infant.
In order to achieve the purpose, the invention is realized by the following technical scheme:
an infant formula milk powder added with yolk phospholipid, soybean phospholipid and milk phospholipid comprises the following raw materials in parts by weight: 50-200 parts of raw milk or raw goat milk, 250-400 parts of desalted whey powder, 50-100 parts of partially hydrolyzed whey protein powder, 20-50 parts of buttermilk powder, 50-100 parts of 1, 3-dioleate-2-palmitic acid triglyceride, 30-100 parts of soybean oil, 20-40 parts of olive oil, 10-50 parts of anhydrous cream, 20-50 parts of fructo-oligosaccharide powder, 5-10 parts of galacto-oligosaccharide, 1-5 parts of compound vitamin, 1-3 parts of compound mineral substance, 1-5 parts of calcium hydrophosphate, 1-5 parts of calcium carbonate, 0-5 parts of sodium citrate, 0-5 parts of potassium chloride, 1-6 parts of potassium carbonate, 0-3 parts of tricalcium phosphate, 1-3 parts of lecithin, 1-3 parts of soybean lecithin, 1-3 parts of choline chloride, 0-1 part of L-carnitine, 0-1 part of inositol, 1-5 parts of mono-diglycerol fatty acid ester, 5-10 parts of DHA powder and 5-15 parts of ARA powder, 0-2 parts of vitamin C, 0-3 parts of lutein and 120-2 parts of animal bifidobacterium Bb-120.
Wherein, the raw cow/goat milk has the following functions: (1) the raw cow/goat milk is rich in immunoglobulin and lactoferrin, can efficiently resist viruses and bacteria, and is beneficial to enhancing the physique and improving the immunity; (2) the raw cow/goat milk is rich in growth factors and proteins, can promote the growth and development of the nervous system, the digestive system, the fiber cells, the skin system and the like in the body, helps to repair tissue cells, promotes wound healing and accelerates postoperative rehabilitation; (3) the raw cattle/sheep are rich in calcium, and are helpful for promoting the growth and development of bones and teeth.
Desalting whey powder: the main components of the whey powder are whey protein and lactose. Desalted whey powder is prepared by removing mineral salts from pasteurized fresh whey without any preservative by physical separation techniques (electrodialysis, ion exchange), cryoconcentration and spray drying. For infants, the kidney burden of the infants is increased due to the high content of the mineral substances, so the mineral substances are removed, and in addition, the protein proportion can be adjusted by adding the desalted whey powder into the milk powder, so that the protein proportion is closer to that in the breast milk, and the infant milk is more suitable for the growth and development requirements of the infants.
Partially hydrolyzed whey protein powder: hydrolyzed whey protein is the product of the hydrolysis of concentrated whey or lactalbumin by proteases (an enzyme that is required by the human body to digest protein after we have ingested any protein), a process that breaks down the protein into smaller molecules, called polypeptides, that can be directly absorbed by the body with little or no need for digestion. The main purpose of hydrolysis of whey proteins by proteases is to reduce protein allergy, and this process makes hydrolyzed whey proteins also relatively expensive in price. However, the protein content of hydrolysed whey protein is about 80-90% (absolutely not isolated high), lactose about 0.5-1%, fat about 0.5-8%. Since properly hydrolyzed protein loses its ability to induce allergy in humans, it is mainly added to hypoallergenic infant formulas, as well as to specialty nutritional foods, such as liquid foods or special dietary supplements provided to patients through tubes, etc.
Cow/sheep buttermilk powder: the buttermilk powder is rich in milk phosphatide and milk fat globule membrane, and the milk phosphatide is very important for the development of the brain and nerves of infants. And the buttermilk powder has rich phospholipid content, so that the buttermilk powder is greatly helpful for emulsifying and brewing the formula milk powder.
1, 3-dioleoyl-2-palmitic acid triglyceride is also called OPO structure fat, is a structured fat simulating breast milk lipid, and is used for improving the proportion of sn-2 position palmitic acid in milk powder by an enzymatic transesterification technology. Compared with the common milk powder added with palm oil, the OPO milk powder contains more easily absorbed sn-2 palmitic acid, and is particularly beneficial to the babies with constipation and poor gastrointestinal absorption: OPO can provide energy for the growth and development of the baby; OPO better promotes the absorption of fatty acid; OPO can better promote the absorption of minerals such as calcium and the like and vitamins; OPO can reduce insoluble calcium soap in the excrement of the babies, and relieve constipation and difficult defecation; OPO can improve the intestinal health of the baby.
The olive oil has the function of providing fat, and compared with common vegetable oil, the olive oil helps to balance metabolism and promote the development of nervous system, skeleton and brain of infants. Olive oil is the oil most suitable for infant consumption, depending on its composition and digestibility. Half of the infant's calories come from fat in the mother's milk and after weaning, the calories needed are obtained from dietary fat. The ratio of linolenic acid and linoleic acid which can not be synthesized by human body in the olive oil nutrient components is similar to that of breast milk, and the olive oil is easy to absorb and can promote the growth and development of nerves and bones of infants.
Soybean oil functions to provide the fat needed for infant growth.
The anhydrous cream has the functions of providing fat for infants and endowing the product with pure milk fragrance.
Both fructooligosaccharides and galactooligosaccharides belong to dietary fibers. Fructooligosaccharides are a natural active substance. It is an activated proliferation factor of intestinal bifidobacteria, can obviously improve the microbial population proportion in the intestinal tract and regulate the intestinal homeostasis; can promote the absorption and utilization of trace elements of iron and calcium to prevent osteoporosis; can reduce liver toxin, can generate anticancer organic acid in intestines, and has obvious cancer prevention function. The galacto-oligosaccharide is a functional oligosaccharide with natural attribute, is a prebiotic which can be utilized by 8 large probiotics in human intestinal tracts, is an excellent nutrient source and an effective proliferation factor of beneficial bacteria such as bifidobacterium, lactobacillus acidophilus and the like in the human intestinal tracts, and can improve the digestion and absorption functions of the human intestinal tracts. The galacto-oligosaccharide has strong acid resistance and heat resistance, and cannot lose the original characteristics due to high-temperature sterilization and decomposition of gastric acid of a human body in the processing process. In 2008, the Ministry of health of the people's republic of China approved galactooligosaccharides as a new resource food. The clinical research results show that if the galacto-oligosaccharide and the fructo-oligosaccharide are added in a proper amount according to a certain proportion in the infant formula, the beneficial flora such as bifidobacterium, lactobacillus and the like can be promoted to reproduce and grow in the intestinal tract, and the infant formula has the effect similar to breast milk oligosaccharide on the intestinal tract of infants.
The compound vitamin has the function of providing the vitamin needed by the infants.
The compound mineral has the function of providing minerals required by infants.
Soybean lecithin: soybean phospholipids can generate choline, glycerophospholipids and fatty acids through in vivo hydrolysis. Choline continues to be converted into acetylcholine in the body, which has a refreshing effect. Therefore, the soybean lecithin can improve the neurochemical function and the brain function of a human body, slow down the degeneration and death of brain cells, and enhance the physique and the memory. It can be used to simulate the composition of human milk phospholipid and has certain emulsifying effect.
The egg yolk phospholipid is characterized in that at least 95 percent of ARA and DHA of long-chain unsaturated fatty acid (namely DHA and ARA) combined with the phospholipid with a unique natural structure are phospholipid type, and the egg yolk phospholipid plays a role in simulating the composition of breast milk phospholipid and plays a certain emulsification role. The yolk phospholipid model Akonio ELIP3020 used in the invention is also the source of natural choline.
DHA is classified into triglyceride Type (TG), methyl ester type (ME), ethyl ester type (EE) and lecithin type (PC-DHA) in terms of existence form; the source of the feed is divided into fish oil DHA, algae oil DHA and yolk DHA. DHA derived from fish oil and algae oil is triglyceride type, methyl ester type or ethyl ester type, and DHA derived from egg yolk is lecithin type. The structural difference or existing state of DHA has a great influence on the digestion and absorption of DHA in human body. Whether of the ethyl ester type, the methyl ester type or the triglyceride type, are absorbed in the body by passive diffusion. The absorptivity of ethyl ester type DHA is only about 20%, and the absorptivity of triglyceride type DHA existing in a natural form is far higher than that of ethyl ester type DHA and is only about 50%. In recent years, scientific research shows that the lecithin-type DHA of a new generation is absorbed in vivo in an active absorption mode, and the absorption rate is close to 100%. The results of the research conducted by professor group of Jin-Hyang SONG, Yoshikazu INOUE, and Teruo MIYAZAWAt, university of northeast Japan, showed that less than 10% of lecithin-type DHA was lost, 64% of ethyl ester-type DHA was lost, and 97% of triglyceride-type DHA was lost by oxidation for 10 weeks.
TABLE 3 comparison table of phospholipid type DHA and common ethyl ester type DHA
DHA and ARA: DHA, named as brain gold, is called as docosahexaenoic acid in science, is highly unsaturated fatty acid indispensable to brain nutrition, accounts for 30% -45% of total fat content in brain, plays an extremely important role in brain cells, and is extremely beneficial to brain nerve conduction and growth and development of synapse. ARA, the scientific name "arachidonic acid", is a long chain polyunsaturated fatty acid of the n-6 type, which, although it can be derived from linoleic acid in the human body, is still synthesized in insufficient quantities, especially in infants, and thus the development of the brain and nervous system may be severely retarded, and it is therefore also necessary to supply it from food. ARA is helpful for brain development, improving visual acuity, esterifying cholesterol, increasing blood vessel elasticity, reducing blood viscosity, and improving immunity. According to the reasonable nutrition standards published by the world health organization and the food and agriculture organization of the United nations, the scientific intake of DHA in infancy is 20 mg/kg/day and the scientific intake of ARA is 40 mg/kg/day.
Lutein: lutein belongs to one of the known 600 carotenoids. Lutein is found in corn, egg yolk, and other yellow and green plants and vegetables, but also in eye tissues, especially the pigment of the retina and parts of the lens. Lutein is the major pigment in the macular region of the retina of the human eye. The human eye contains high amounts of lutein, an element that is not produced by the human body and must be supplemented by the ingestion of lutein. The lutein has effects of protecting retina and eyesight.
Bifidobacterium animalis Bb-12: bb-12 has the functions of regulating intestinal flora and improving immunity. Bb-12 has excellent acid resistance and bile resistance, and excellent intestinal adhesion capability. Inhibiting pathogenic bacteria, enhancing barrier function and immune interaction. Clinical studies have demonstrated that Bb-12 is viable through the gastrointestinal tract and maintains a healthy gastrointestinal flora. In addition, Bb-12 improves gut function, prevents diarrhea, and reduces side effects of antibiotic therapy, such as antibiotic-associated diarrhea. In the aspect of immune function, clinical researches show that Bb-12 can improve the resistance of the body to common respiratory tract infection and simultaneously reduce the incidence rate of acute respiratory tract infection.
Further, the raw materials in parts by weight are as follows: 50 parts of raw milk/raw goat milk, 320 parts of desalted whey powder, 80 parts of partially hydrolyzed whey protein powder, 30 parts of buttermilk powder, 80 parts of 1, 3-dioleate-2-palmitic acid triglyceride, 70 parts of soybean oil, 30 parts of olive oil, 25 parts of anhydrous cream, 40 parts of fructo-oligosaccharide powder, 6 parts of galacto-oligosaccharide, 2.5 parts of compound vitamin, 1 part of compound mineral, 3 parts of calcium hydrophosphate, 4 parts of calcium carbonate, 3 parts of sodium citrate, 0.5 part of potassium chloride, 5 parts of potassium carbonate, 1 part of tricalcium phosphate, 2 parts of lecithin, 1 part of soybean lecithin, 2 parts of choline chloride, 0.1 part of L-carnitine, 0.2 part of inositol, 3 parts of mono-diglycerol fatty acid ester, 10 parts of DHA powder, 12 parts of ARA powder, 1 part of vitamin C, 0.5 part of lutein and 120.3 parts of bifidobacterium animalis Bb.
Further, each gram of compound vitamin comprises the following components: 2000-2700 mu gRE of vitamin A, 68-92 mu g of vitamin D, 45-61 mg alpha-TE of vitamin E, 1300-500 mu g of vitamin K, 13000-4060 mu g of vitamin B, 22000-2700 mu g of vitamin B, 62100-2800 mu g of vitamin B, 122-4 mu g of vitamin B, 38-52 mu g of biotin, 16000-22000 mu g of nicotinamide, 450-610 mu g of folic acid, 13000-18000 mu g of pantothenic acid and 400-550 mu g of vitamin C.
Further, the composition of each gram of the compound mineral is as follows: copper: 3000-4100 mu g, 40-54 mg of iron, 40-54 mg of zinc, 200-280 mu g of manganese, 500-680 mu g of iodine and 200-270 mu g of selenium.
Furthermore, the buttermilk powder is cow/sheep buttermilk powder, is a byproduct of butter production, and is rich in milk phospholipids and milk fat globule membrane MFGM.
Further, the cow/sheep buttermilk powder contains 1-3% of total phospholipid, and comprises the following components in percentage by weight: 8-12% of Phosphatidylinositol (PI), 12-16% of Phosphatidylserine (PS), 22-36% of Phosphatidylethanolamine (PE), 26-32% of Phosphatidylcholine (PC) and 20-24% of Sphingomyelin (SM).
Further, the egg yolk phospholipids, model Akonio ELIP3020, are a mixture of high oleic sunflower oil and egg yolk derived phospholipids characterized by long chain unsaturated fatty acids (i.e., DHA and ARA) bound to phospholipids with unique natural structure, at least 95% of the ARA and DHA being phospholipid type. And Akonino ELIP3020 is a source of natural choline.
Further, the total phospholipid content of the Akonio ELIP3020 egg yolk phospholipid is more than 30g/100g, and the Akonio ELIP3020 egg yolk phospholipid specifically comprises the following components: phosphatidylinositol (PI)0.4g/100g, Phosphatidylethanolamine (PE)5g/100g, Phosphatidylcholine (PC)27g/100g, Lysophosphatidylcholine (LPC)0.8g/100g, Lysophosphatidylethanolamine (LPE)0.3g/100g, Sphingomyelin (SPH)1g/100 g.
Further, the soybean phospholipids are a complex mixture, which contains 65-70% of phospholipids, and also contains other triglycerides, fatty acids, sterols, steroid glycosides and esters.
Further, the soybean phospholipids comprise the following phospholipid components: 36.2% of Phosphatidylcholine (PC), 21.4% of Phosphatidylethanolamine (PE), 15.2% of Phosphatidylinositol (PI), 16.1% of Phosphatidylglycerol (PG) and 3.6% of Phosphatidylserine (PS).
Further, the desalted whey powder is D90 desalted whey powder.
Further, the DHA powder and the ARA powder both have the content of 10%.
Furthermore, the addition amount of the bifidobacterium animalis Bb-12 is more than or equal to 1.2 multiplied by 106 CFU/g.
Further, the 1, 3-dioleoyl-2-palmitate is 40% in content.
The production process of the infant formula milk powder comprises the following steps: preparing materials, homogenizing, sterilizing, concentrating and spray drying.
Further, the batching process is as follows: fresh milk and other raw and auxiliary materials are checked and then are put into a shearing mixing tank filled with hot water of 50-60 ℃, the mixing sequence is that desalted whey powder, partially hydrolyzed whey protein powder, buttermilk powder and other powdery products are added, then raw cow/goat milk and compound oil are added, finally feed liquid of vitamin, mineral salt and the like is slowly poured into the mixing tank, and the vitamin and the trace elements are respectively dissolved.
Further, the hydrolysis process of the partially hydrolyzed whey protein powder is as follows: adding 10% KOH solution into the homogenizing tank, and adjusting the pH value of the feed liquid to 6.8-7.0. Dissolving enzyme with keg (noting that the temperature of the dissolved water does not exceed 50 ℃), adding dissolved Trypsin (Pancretic Trypsin Novo 6.0S) and neutral protease (Neutrase 5.0BG) into a tank to be homogenized, stirring, starting recording enzymolysis time, controlling the enzymolysis time for 50min at 53-55 ℃. After the enzymolysis is finished, a proper amount of 10% KOH solution is added to adjust the pH value of the whey to 7.0-7.2.
Further, the homogenization conditions are as follows: the temperature is controlled to be 50-60 ℃, the pressure is 16-20 MPa, and the homogenized material is cooled to 10-20 ℃ in time.
Further, the sterilization and concentration process comprises the following steps: the homogenizing temperature is controlled to be 50-60 ℃, the pressure is 16-20 MPa, and the homogenized material is cooled to 10-20 ℃ in time.
Further, the spray drying process comprises the following steps: feeding the concentrated milk into a spray drying tower, adjusting the pressure of a high-pressure pump to be more than 15MPa when the exhaust temperature reaches 90 ℃ and the intake temperature is more than 130 ℃, starting spray drying, and cooling by a fluidized bed to obtain the milk powder.
Compared with the existing infant formula milk powder on the market, the infant formula milk powder has the advantages that: by adding soybean phospholipid, yolk phospholipid and milk phospholipid and adjusting the proportion, the content and the composition of phospholipid in the formula are close to those of breast milk, and the advantages of DHA & ARA, dietary fiber, probiotics, lutein and other raw materials are combined, so that the formula is closer to the breast milk, rich in nutrition and reasonable in component proportion, the intestinal health and intelligence development are promoted, the cognitive ability of infants is improved, the metabolism is improved, and the growth and development requirements of the infants are met. Wherein, the composition of the composition is close to that of phospholipid in breast milk, and the composition comprises 10-30mg of Phosphatidylinositol (PI), 20-40mg of Phosphatidylserine (PS), 60-150mg of Phosphatidylethanolamine (PE), 20-60mg of Phosphatidylcholine (PC) and 60-100mg of Sphingomyelin (SM).
Detailed Description
The invention will now be further illustrated by reference to the following examples, which are provided by way of illustration only and are not intended to limit the scope of the invention. The "parts" in the following examples each refer to a mass fraction.
The cow/sheep buttermilk powder used in the following examples has a total phospholipid content of 1-3%, and comprises the following components in percentage by weight: 8-12% of Phosphatidylinositol (PI), 12-16% of Phosphatidylserine (PS), 22-36% of Phosphatidylethanolamine (PE), 26-32% of Phosphatidylcholine (PC) and 20-24% of Sphingomyelin (SM).
The total phospholipid content of the egg yolk phospholipids used in the following examples is more than 30g/100g, and the specific compositions are as follows: phosphatidylinositol (PI)0.4g/100g, Phosphatidylethanolamine (PE)5g/100g, Phosphatidylcholine (PC)27g/100g, Lysophosphatidylcholine (LPC)0.8g/100g, Lysophosphatidylethanolamine (LPE)0.3g/100g, Sphingomyelin (SPH)1g/100 g.
The soybean phospholipids used in the following examples had a phospholipid composition of: 36.2% of Phosphatidylcholine (PC), 21.4% of Phosphatidylethanolamine (PE), 15.2% of Phosphatidylinositol (PI), 16.1% of Phosphatidylglycerol (PG) and 3.6% of Phosphatidylserine (PS).
In the following examples, DHA and ARA powders were each a 10% content powder.
The desalted whey powder in the following examples was D90.
The 1, 3-dioleoyl-2-palmitate is present in the following examples at a level of 40%.
The addition amount of Bifidobacterium animalis Bb-12 in the following examples should be not less than 1.2 × 106CFU/g。
Example 1:
an infant formula goat milk powder added with yolk phospholipid, soybean phospholipid and milk phospholipid comprises the following raw materials in parts by weight: 50 parts of raw goat milk, 400 parts of desalted goat whey powder, 80 parts of partially hydrolyzed whey protein powder, 30 parts of sheep buttermilk powder, 80 parts of 1, 3-dioleate-2-palmitic acid triglyceride, 70 parts of soybean oil, 30 parts of olive oil, 25 parts of goat cream, 40 parts of fructo-oligosaccharide powder, 6 parts of galacto-oligosaccharide, 2.5 parts of compound vitamin, 1 part of compound mineral, 3 parts of calcium hydrophosphate, 4 parts of calcium carbonate, 3 parts of sodium citrate, 0.5 part of potassium chloride, 5 parts of potassium carbonate, 1 part of tricalcium phosphate, 2 parts of egg yolk phospholipid, 1 part of soybean phospholipid, 2 parts of choline chloride, 0.1 part of L-carnitine, 0.2 part of inositol, 3 parts of mono-diglycerol fatty acid ester, 10 parts of DHA powder, 12 parts of ARA powder, 1 part of vitamin C, 0.5 part of lutein and 120.3 parts of bifidobacterium animalis Bb.
The composition of each gram of the compound vitamin is as follows: 2000-2700 mu gRE of vitamin A, 68-92 mu g of vitamin D, 45-61 mg of alpha-TE of vitamin E and K of vitamin K1300-500 mug of vitamin B13000-4060 μ g, vitamin B22000-2700 ug, vitamin B62100-2800 μ g of vitamin B122-4 μ g, 38-52 μ g biotin, 16000-22000 μ g nicotinamide, 450-610 μ g folic acid, 13000-18000 μ g pantothenic acid, 400-550 μ g vitamin C.
The composition of each gram of the composite mineral is as follows: copper: 3000-4100 mu g, 40-54 mg of iron, 40-54 mg of zinc, 200-280 mu g of manganese, 500-680 mu g of iodine and 200-270 mu g of selenium.
Example 2:
an infant formula milk powder added with yolk phospholipid, soybean phospholipid and milk phospholipid comprises the following raw materials in parts by weight: 50 parts of raw milk, 320 parts of desalted whey powder, 80 parts of partially hydrolyzed whey protein powder, 30 parts of cow buttermilk powder, 80 parts of 1, 3-dioleate-2-palmitic acid triglyceride, 70 parts of soybean oil, 30 parts of olive oil, 25 parts of anhydrous cream, 40 parts of fructo-oligosaccharide powder, 6 parts of galacto-oligosaccharide, 2.5 parts of compound vitamin, 1 part of compound mineral substance, 3 parts of calcium hydrophosphate, 4 parts of calcium carbonate, 3 parts of sodium citrate, 0.5 part of potassium chloride, 5 parts of potassium carbonate, 1 part of tricalcium phosphate, 2 parts of egg yolk phospholipid, 1 part of soybean phospholipid, 2 parts of choline chloride, 0.1 part of L-carnitine, 0.2 part of inositol, 3 parts of mono-diglycerol ester, 10 parts of DHA powder, 12 parts of ARA powder, 1 part of vitamin C, 0.5 part of lutein and 120.3 parts of bifidobacterium animalis Bb.
The composition of each gram of the compound vitamin is as follows: 2000-2700 mu gRE of vitamin A, 68-92 mu g of vitamin D, 45-61 mg of alpha-TE of vitamin E and K of vitamin K1300-500 mug of vitamin B13000-4060 μ g, vitamin B22000-2700 ug, vitamin B62100-2800 μ g of vitamin B122-4 μ g, 38-52 μ g biotin, 16000-22000 μ g nicotinamide, 450-610 μ g folic acid, 13000-18000 μ g pantothenic acid, 400 ℃550μg。
The composition of each gram of the composite mineral is as follows: copper: 3000-4100 mu g, 40-54 mg of iron, 40-54 mg of zinc, 200-280 mu g of manganese, 500-680 mu g of iodine and 200-270 mu g of selenium.
Example 3
The preparation process of the embodiment 1-2 includes the following steps:
(1) preparing materials: after checking the relevant information, the raw and auxiliary materials are accurately metered into a shear mixing tank filled with hot water according to the formula for mixing. The proportioning procedure is that 50-60 ℃ (temperature can be adjusted according to seasons) proportioning water is added into a proportioning tank, shearing and stirring are started, whey powder, milk powder and other powdery raw materials are added, then oil is added, finally, dissolved mineral salt and other raw materials are slowly added into a mixing tank, and the mixture is stirred for about 10 minutes and then is added into a tank to be homogenized.
(2) Homogenizing and sterilizing: the materials are positioned before homogenization, water quantity is replenished in a mixing tank, different concentrations are prepared according to different varieties, the materials are uniformly mixed, and the materials enter a homogenizer for homogenization. After the material pump is opened, the homogenizing pressure is slowly adjusted to be (16-20) MPa, and after the homogenization, the material liquid is cooled and pumped into a temporary storage tank for temporary storage after short-time sterilization at the temperature of 110 ℃ and 120 ℃ (about 6 seconds). Before homogenization is completed, the foam in the mixing cylinder is flushed with warm water, and the fat floats into lumps.
(3) Cooling and storing materials: cooling the homogenized and sterilized materials to 10-20 ℃ in time, cooling by cold air discharge according to the actual production condition, adding the dissolved vitamins, and uniformly stirring. The temporary storage time should not exceed 2 hours, and the temporary storage tank needs to be added with stirring.
(4) Sterilization and concentration: when the pressure of the boiler reaches 0.8MPa, the pressure of the compressed air reaches over 0.4MPa, the temperature of the sterilizer reaches 92-98 ℃, and the evaporation temperature meets the process requirements, the feed valve is opened, and the reflux valve is closed to feed materials to the thick milk tank. The pressure of the triple effect cylinder is more than or equal to 0.8MPa, and the pressure of the hot-pressing pump is 0.3-0.8 MPa. The sterilization temperature is 92-98 ℃ for about 15 s. The primary evaporation temperature is 68-75 ℃, the secondary evaporation temperature is 54-60 ℃, the tertiary evaporation temperature is 46-54 ℃, and the cooling water discharge temperature is less than or equal to 40 ℃. The vacuum of the first-effect separator is-0.065-0.071 MPa, the vacuum of the second-effect separator is-0.081-0.084 MPa, and the vacuum of the third-effect separator is-0.084-0.091 MPa.
(5) Spray drying: feeding the concentrated milk into a spray drying tower, adjusting the pressure of a high-pressure pump to be more than 15MPa when the exhaust temperature reaches 90 ℃ and the intake temperature is more than 130 ℃, starting spray drying, and cooling by a fluidized bed to obtain the milk powder.
Comparative example 4
EXAMPLE 2 phospholipid content and composition in one infant formula supplemented with egg yolk phospholipids, soya phospholipids and milk phospholipids and three commercially available infant formulas compared to breast milk
4.1 formula of three commercially available infant formula milk powders is as follows:
wherein the commercial milk powder a only contains soybean phospholipid, the commercial milk powder b contains milk fat globule membrane (namely milk phospholipid), and the commercial milk powder c contains soybean phospholipid.
4.1.1 commercial milk powder a ingredient table: raw milk, desalted whey powder, refined vegetable oil, lactose, galacto-oligosaccharide, concentrated whey protein powder, skimmed milk powder, arachidonic acid, docosahexaenoic acid, fructo-oligosaccharide, lactoferrin, calcium carbonate, calcium hydrogen phosphate, magnesium chloride, potassium chloride, dipotassium hydrogen phosphate, sodium citrate, sodium chloride, potassium iodide, sodium selenite, ferric pyrophosphate, zinc sulfate, copper sulfate, manganese sulfate, vitamin C, vitamin A, vitamin D, vitamin E, vitamin K, vitamin B1Vitamin B2Vitamin B6Vitamin B12Nicotinic acid, pantothenic acid, folic acid, biotin, inositol, taurine, choline, L-carnitine, nucleotide and phospholipid.
4.1.2 commercial milk powder b ingredient table: skimmed milk powder, desalted whey powder, lactose, 1, 3-dioleate-2-palmitic acid triglyceride, whey protein powder, soybean oil, sunflower seed oil, corn oil, casein, anhydrous cream, galacto-oligosaccharide, fructo-oligosaccharide, taurine, nucleotide, docosahexaenoic acid, arachidonic acid, Bifidobacterium lactis HN019, Bifidobacterium animalis Bb-12, vitamin C, vitamin A, vitamin D, vitamin E, vitamin K, vitamin B1Vitamin B2Vitamin B6Vitamin B12Nicotinic acid, nicotinic acid,Pantothenic acid, folic acid, biotin, choline chloride, calcium carbonate, ferrous sulfate, zinc sulfate, copper sulfate and potassium iodide.
4.1.3 commercial milk powder c ingredient table: skimmed milk powder, vegetable oil, lactose, white sugar, galacto-oligosaccharide, calcium carbonate, sodium citrate, potassium citrate, tricalcium phosphate, ferrous sulfate, zinc sulfate, copper sulfate, manganese sulfate, potassium iodide, sodium selenite, L-sodium ascorbate, choline bitartrate, choline chloride, ascorbyl palmitate, mixed tocopherol concentrate, vitamin C, vitamin A, vitamin D, vitamin E, vitamin K, and vitamin B1Vitamin B2Vitamin B6Vitamin B12Nicotinic acid, pantothenic acid, folic acid, biotin, bifidobacterium animalis Bb-12, nucleotide, phospholipid, lutein, docosahexaenoic acid and arachidonic acid.
4.1.4 the contents of various phospholipids in the four infant formula milk powders and breast milk are as follows:
from the above table, it can be seen that: the phospholipid composition and content of the infant formula milk powder described in formula example 2 are the closest to those of breast milk, while the phospholipid content of the commercial milk powder a and c is not much different from that of the formula due to the addition of soybean phospholipid, but the phospholipid composition is greatly different from that of the breast milk. The commercial milk powder b has the lowest phospholipid content, but the phospholipid composition is closer to that of breast milk.
Claims (9)
1. An infant formula milk powder added with yolk phospholipid, soybean phospholipid and milk phospholipid is characterized by comprising the following raw materials in parts by weight: 50-200 parts of raw milk or raw goat milk, 250-400 parts of desalted whey powder, 50-100 parts of partially hydrolyzed whey protein powder, 20-50 parts of buttermilk powder, 50-100 parts of 1, 3-dioleate-2-palmitic acid triglyceride, 30-100 parts of soybean oil, 20-40 parts of olive oil, 10-50 parts of anhydrous cream, 20-50 parts of fructo-oligosaccharide powder, 5-10 parts of galacto-oligosaccharide, 1-5 parts of compound vitamin, 1-3 parts of compound mineral substance, 1-5 parts of calcium hydrophosphate, 1-5 parts of calcium carbonate, 0-5 parts of sodium citrate, 0-5 parts of potassium chloride, 1-6 parts of potassium carbonate, 0-3 parts of tricalcium phosphate, 1-3 parts of lecithin, 1-3 parts of soybean lecithin, 1-3 parts of choline chloride, 0-1 part of L-carnitine, 0-1 part of inositol, 1-5 parts of mono-diglycerol fatty acid ester, 5-10 parts of DHA powder and 5-15 parts of ARA powder, 0-2 parts of vitamin C, 0-3 parts of lutein and 120-2 parts of animal bifidobacterium Bb-120.
2. The infant formula milk powder of claim 1, wherein the infant formula milk powder comprises the following raw materials in parts by weight: 50 parts of raw milk/raw goat milk, 320 parts of desalted whey powder, 80 parts of partially hydrolyzed whey protein powder, 30 parts of buttermilk powder, 80 parts of 1, 3-dioleate-2-palmitic acid triglyceride, 70 parts of soybean oil, 30 parts of olive oil, 25 parts of anhydrous cream, 40 parts of fructo-oligosaccharide powder, 6 parts of galacto-oligosaccharide, 2.5 parts of compound vitamin, 1 part of compound mineral, 3 parts of calcium hydrophosphate, 4 parts of calcium carbonate, 3 parts of sodium citrate, 0.5 part of potassium chloride, 5 parts of potassium carbonate, 1 part of tricalcium phosphate, 2 parts of lecithin, 1 part of soybean lecithin, 2 parts of choline chloride, 0.1 part of L-carnitine, 0.2 part of inositol, 3 parts of mono-diglycerol fatty acid ester, 10 parts of DHA powder, 12 parts of ARA powder, 1 parts of vitamin C, 0.5 part of lutein and 120.3 parts of animal bifidobacterium Bb.
3. The infant formula of claim 1, wherein: the composition of the compound vitamin per gram is as follows: 2000-2700 mu gRE of vitamin A, 68-92 mu g of vitamin D, 45-61 mg alpha-TE of vitamin E, 1300-500 mu g of vitamin K, 13000-4060 mu g of vitamin B, 22000-2700 mu g of vitamin B, 62100-2800 mu g of vitamin B, 122-4 mu g of vitamin B, 38-52 mu g of biotin, 16000-22000 mu g of nicotinamide, 450-610 mu g of folic acid, 13000-18000 mu g of pantothenic acid and 400-550 mu g of vitamin C.
4. The infant formula of claim 1, wherein: the composition of each gram of compound mineral is as follows: copper: 3000-4100 mu g, 40-54 mg of iron, 40-54 mg of zinc, 200-280 mu g of manganese, 500-680 mu g of iodine and 200-270 mu g of selenium.
5. The infant formula of claim 1, wherein: the buttermilk powder contains 1-3% of total phospholipid, and comprises the following components in percentage by weight: 8-12% of Phosphatidylinositol (PI), 12-16% of Phosphatidylserine (PS), 22-36% of Phosphatidylethanolamine (PE), 26-32% of Phosphatidylcholine (PC) and 20-24% of Sphingomyelin (SM).
6. The infant formula of claim 1, wherein: the egg yolk phospholipid is Akonino ELIP3020, the total phospholipid content is more than 30g/100g, and the egg yolk phospholipid specifically comprises the following components: phosphatidylinositol (PI)0.4g/100g, Phosphatidylethanolamine (PE)5g/100g, Phosphatidylcholine (PC)27g/100g, Lysophosphatidylcholine (LPC)0.8g/100g, Lysophosphatidylethanolamine (LPE)0.3g/100g, Sphingomyelin (SPH)1g/100 g.
7. The infant formula of claim 1, wherein: the soybean phospholipid contains 65-70% of phospholipid, and the phospholipid comprises the following components: 36.2% of Phosphatidylcholine (PC), 21.4% of Phosphatidylethanolamine (PE), 15.2% of Phosphatidylinositol (PI), 16.1% of Phosphatidylglycerol (PG) and 3.6% of Phosphatidylserine (PS).
8. A process for the production of an infant formula according to claim 1, characterized in that it comprises the following steps: (1) preparing materials: checking fresh milk and other raw and auxiliary materials, adding into a shearing mixing tank containing 50-60 deg.C hot water, sequentially mixing desalted goat whey powder, concocted goat whey powder, fructo-oligosaccharide powder, etc., adding raw goat milk, adding compound oils, and slowly pouring vitamin and mineral salt into the mixing tank, wherein vitamins and microelements should be dissolved respectively; (2) homogenizing: the homogenizing temperature is controlled to be 50-60 ℃, the pressure is 16-20 MPa, and the homogenized material is cooled to 10-20 ℃ in time; (3) sterilization and concentration: the sterilization temperature is 92-98 ℃, the sterilized milk enters a triple-effect evaporator for concentration, and the amount of the concentrated dry matter is about 40-55%; (4) spray drying: feeding the concentrated milk into a spray drying tower, adjusting the pressure of a high-pressure pump to be more than 15MPa when the exhaust temperature reaches 90 ℃ and the intake temperature is more than 130 ℃, starting spray drying, and cooling by a fluidized bed to obtain the milk powder.
9. The process for producing an infant formula according to claim 8, wherein: wherein, the hydrolysis process of the partially hydrolyzed whey protein powder is as follows: adding 10% KOH solution into the homogenizing tank, and adjusting the pH value of the feed liquid to 6.8-7.0; dissolving enzyme with a small barrel in advance, adding the dissolved trypsin and neutral protease into a tank to be homogenized, stirring, starting recording enzymolysis time, and controlling the enzymolysis time for 50min at the temperature of 53-55 ℃; after the enzymolysis is finished, a proper amount of 10% KOH solution is added to adjust the pH value of the whey to 7.0-7.2.
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