CN104010656B - 使用免疫球蛋白和c1-抑制剂的联合疗法 - Google Patents
使用免疫球蛋白和c1-抑制剂的联合疗法 Download PDFInfo
- Publication number
- CN104010656B CN104010656B CN201280046349.8A CN201280046349A CN104010656B CN 104010656 B CN104010656 B CN 104010656B CN 201280046349 A CN201280046349 A CN 201280046349A CN 104010656 B CN104010656 B CN 104010656B
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- inh
- immunoglobulin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39516—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum from serum, plasma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161538832P | 2011-09-24 | 2011-09-24 | |
US61/538,832 | 2011-09-24 | ||
PCT/EP2012/068643 WO2013041677A1 (en) | 2011-09-24 | 2012-09-21 | Combination therapy using immunoglobulin and c1-inhibitor |
Publications (2)
Publication Number | Publication Date |
---|---|
CN104010656A CN104010656A (zh) | 2014-08-27 |
CN104010656B true CN104010656B (zh) | 2016-02-24 |
Family
ID=46881067
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201280046349.8A Active CN104010656B (zh) | 2011-09-24 | 2012-09-21 | 使用免疫球蛋白和c1-抑制剂的联合疗法 |
Country Status (11)
Country | Link |
---|---|
US (1) | US10471142B2 (ko) |
EP (1) | EP2758076B1 (ko) |
JP (1) | JP6190368B2 (ko) |
KR (1) | KR101956585B1 (ko) |
CN (1) | CN104010656B (ko) |
AU (1) | AU2012311483B2 (ko) |
CA (1) | CA2848510A1 (ko) |
DK (1) | DK2758076T3 (ko) |
ES (1) | ES2714999T3 (ko) |
HK (1) | HK1200334A1 (ko) |
WO (1) | WO2013041677A1 (ko) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL2683397T3 (pl) | 2011-03-09 | 2018-01-31 | Csl Behring Gmbh | Inhibitory czynnika XII do podawania w zabiegach medycznych obejmujących kontakt z powierzchniami sztucznymi |
JP6289511B2 (ja) * | 2013-02-28 | 2018-03-07 | ツェー・エス・エル・ベーリング・ゲー・エム・ベー・ハー | 羊水塞栓の治療剤 |
EP2964255B1 (en) * | 2013-03-08 | 2020-11-04 | CSL Behring GmbH | Treatment and prevention of remote ischemia-reperfusion injury |
CN111529708A (zh) | 2013-03-15 | 2020-08-14 | 夏尔维洛药品公司 | 用于预防和治疗与c1酯酶抑制剂缺乏相关的病症的c1-inh组合物和方法 |
WO2014182631A1 (en) * | 2013-05-06 | 2014-11-13 | Baxter International Inc. | Treatment of alzheimer's disease subpopulations with pooled immunoglobulin g |
CN111388655A (zh) * | 2013-11-22 | 2020-07-10 | 夏尔维洛药品公司 | 用c1-酯酶抑制剂治疗器官移植患者中的抗体介导的排斥的方法 |
US20180036394A1 (en) * | 2015-02-20 | 2018-02-08 | Csl Behring Gmbh | Pharmaceutical formulations of c1 esterase inhibitor |
CA2986957A1 (en) | 2015-06-03 | 2016-12-08 | Children's Hospital Medical Center | Compositions and methods for treating neonatal biliary atresia |
AU2017305856A1 (en) | 2016-08-05 | 2019-03-21 | Csl Behring Gmbh | Pharmaceutical formulations of C1 esterase inhibitor |
WO2022251654A1 (en) * | 2021-05-28 | 2022-12-01 | West Virginia University Board of Governors on behalf of West Virginia University | Mitoneet ligands for use in protection from tissue ischemic reperfusion injury |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1750844A (zh) * | 2003-02-21 | 2006-03-22 | 唐纳士公司 | 用于预防和治疗与局部缺血-再灌注损伤相关的组织损伤的方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2009158A (en) * | 1934-08-01 | 1935-07-23 | Ophthalmological Foundation In | Ophthalmic ergograph |
DE3228502A1 (de) | 1982-07-30 | 1984-02-02 | Behringwerke Ag, 3550 Marburg | Verfahren zur herstellung des c1-inaktivators und seine verwendung |
DE4222534A1 (de) | 1992-07-09 | 1994-01-13 | Behringwerke Ag | Verwendung von Komplement-Inhibitoren zur Herstellung eines Arzneimittels zur Prophylaxe und Therapie von entzündlichen Darm- und Hauterkrankungen sowie Purpura |
DE4227762A1 (de) | 1992-08-24 | 1994-03-03 | Behringwerke Ag | Verwendung eines Kallikrein-Inhibitors zur Herstellung eines Arzneimittels zur Prophylaxe und Therapie bestimmter Krankheiten |
US5827832A (en) | 1995-03-06 | 1998-10-27 | Interneuron Pharmaceuticals, Inc. | Method of protecting brain tissue from cerebral infarction subsequent to ischemia |
AU6083899A (en) | 1999-09-16 | 2001-04-17 | Aventis Behring Gmbh | Combination of c1-inh and lung surfactant for the treatment of respiratory disorders |
US8053569B2 (en) * | 2005-10-07 | 2011-11-08 | Armagen Technologies, Inc. | Nucleic acids encoding and methods of producing fusion proteins |
WO2007073186A2 (en) * | 2005-12-21 | 2007-06-28 | Pharming Intellectual Property Bv | Use of c1 inhibitor for the prevention of ischemia-reperfusion injury |
US20100143325A1 (en) * | 2008-12-09 | 2010-06-10 | Vascular Laboratory, Inc. | Composition And Methods Involving Thrombolytic Agents |
EP2233499A1 (en) * | 2009-03-26 | 2010-09-29 | CSL Behring AG | Antibody composition with altered Fab sialylation |
AR076607A1 (es) | 2009-05-27 | 2011-06-22 | Baxter Int | Composicion acuosa. metodo para producir una preparacion altamente concentrada de inmunoglobulina de uso subcutaneo |
-
2012
- 2012-09-21 ES ES12761739T patent/ES2714999T3/es active Active
- 2012-09-21 CA CA2848510A patent/CA2848510A1/en active Pending
- 2012-09-21 WO PCT/EP2012/068643 patent/WO2013041677A1/en active Application Filing
- 2012-09-21 KR KR1020147010605A patent/KR101956585B1/ko active IP Right Grant
- 2012-09-21 US US14/346,478 patent/US10471142B2/en active Active
- 2012-09-21 DK DK12761739.7T patent/DK2758076T3/en active
- 2012-09-21 JP JP2014531244A patent/JP6190368B2/ja active Active
- 2012-09-21 CN CN201280046349.8A patent/CN104010656B/zh active Active
- 2012-09-21 EP EP12761739.7A patent/EP2758076B1/en active Active
- 2012-09-21 AU AU2012311483A patent/AU2012311483B2/en active Active
-
2015
- 2015-01-23 HK HK15100811.0A patent/HK1200334A1/xx unknown
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1750844A (zh) * | 2003-02-21 | 2006-03-22 | 唐纳士公司 | 用于预防和治疗与局部缺血-再灌注损伤相关的组织损伤的方法 |
Non-Patent Citations (1)
Title |
---|
Neuroprotection in Stroke by Complement Inhibition and Immunoglobulin Therapy;Thiruma V. Arumugama et al.;《Neuroscience》;20090206;第158卷(第3期);1074-1089 * |
Also Published As
Publication number | Publication date |
---|---|
CN104010656A (zh) | 2014-08-27 |
KR101956585B1 (ko) | 2019-03-11 |
AU2012311483B2 (en) | 2016-03-10 |
AU2012311483A1 (en) | 2013-05-16 |
HK1200334A1 (en) | 2015-08-07 |
EP2758076A1 (en) | 2014-07-30 |
DK2758076T3 (en) | 2019-04-01 |
JP6190368B2 (ja) | 2017-08-30 |
ES2714999T3 (es) | 2019-05-31 |
CA2848510A1 (en) | 2013-03-28 |
KR20140075753A (ko) | 2014-06-19 |
EP2758076B1 (en) | 2018-12-12 |
US10471142B2 (en) | 2019-11-12 |
WO2013041677A1 (en) | 2013-03-28 |
US20140234293A1 (en) | 2014-08-21 |
JP2014526541A (ja) | 2014-10-06 |
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GR01 | Patent grant |