CN103990150A - Aerogenesis capsule for barium meal radiography and preparation method thereof - Google Patents
Aerogenesis capsule for barium meal radiography and preparation method thereof Download PDFInfo
- Publication number
- CN103990150A CN103990150A CN201410192786.1A CN201410192786A CN103990150A CN 103990150 A CN103990150 A CN 103990150A CN 201410192786 A CN201410192786 A CN 201410192786A CN 103990150 A CN103990150 A CN 103990150A
- Authority
- CN
- China
- Prior art keywords
- capsule
- barium meal
- aerogenic
- powder
- gas producing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229910052788 barium Inorganic materials 0.000 title claims abstract description 30
- DSAJWYNOEDNPEQ-UHFFFAOYSA-N barium atom Chemical compound [Ba] DSAJWYNOEDNPEQ-UHFFFAOYSA-N 0.000 title claims abstract description 30
- 239000002775 capsule Substances 0.000 title claims abstract description 30
- 235000012054 meals Nutrition 0.000 title claims abstract description 30
- 238000002360 preparation method Methods 0.000 title claims abstract description 9
- 238000002601 radiography Methods 0.000 title abstract 5
- 239000000843 powder Substances 0.000 claims abstract description 28
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims abstract description 14
- URAYPUMNDPQOKB-UHFFFAOYSA-N triacetin Chemical compound CC(=O)OCC(OC(C)=O)COC(C)=O URAYPUMNDPQOKB-UHFFFAOYSA-N 0.000 claims abstract description 14
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 12
- 108010010803 Gelatin Proteins 0.000 claims abstract description 10
- 239000012153 distilled water Substances 0.000 claims abstract description 10
- 229920000159 gelatin Polymers 0.000 claims abstract description 10
- 239000008273 gelatin Substances 0.000 claims abstract description 10
- 235000019322 gelatine Nutrition 0.000 claims abstract description 10
- 235000011852 gelatine desserts Nutrition 0.000 claims abstract description 10
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 claims abstract description 7
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims abstract description 7
- 229930195725 Mannitol Natural products 0.000 claims abstract description 7
- 239000002202 Polyethylene glycol Substances 0.000 claims abstract description 7
- 229920002472 Starch Polymers 0.000 claims abstract description 7
- 229930003427 Vitamin E Natural products 0.000 claims abstract description 7
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims abstract description 7
- 239000000594 mannitol Substances 0.000 claims abstract description 7
- 235000010355 mannitol Nutrition 0.000 claims abstract description 7
- 229920001223 polyethylene glycol Polymers 0.000 claims abstract description 7
- 235000010413 sodium alginate Nutrition 0.000 claims abstract description 7
- 239000000661 sodium alginate Substances 0.000 claims abstract description 7
- 229940005550 sodium alginate Drugs 0.000 claims abstract description 7
- 239000008107 starch Substances 0.000 claims abstract description 7
- 235000019698 starch Nutrition 0.000 claims abstract description 7
- 229940046009 vitamin E Drugs 0.000 claims abstract description 7
- 235000019165 vitamin E Nutrition 0.000 claims abstract description 7
- 239000011709 vitamin E Substances 0.000 claims abstract description 7
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 claims abstract description 4
- 239000002994 raw material Substances 0.000 claims abstract description 4
- 239000003292 glue Substances 0.000 claims description 12
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims description 6
- 150000001875 compounds Chemical class 0.000 claims description 6
- 150000003904 phospholipids Chemical class 0.000 claims description 6
- 230000008020 evaporation Effects 0.000 claims description 3
- 238000001704 evaporation Methods 0.000 claims description 3
- 238000010438 heat treatment Methods 0.000 claims description 3
- 238000007654 immersion Methods 0.000 claims description 3
- 229910000030 sodium bicarbonate Inorganic materials 0.000 claims description 3
- 235000017557 sodium bicarbonate Nutrition 0.000 claims description 3
- 210000000214 mouth Anatomy 0.000 abstract description 7
- 230000009286 beneficial effect Effects 0.000 abstract description 2
- 239000001087 glyceryl triacetate Substances 0.000 abstract 1
- 235000013773 glyceryl triacetate Nutrition 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 231100000344 non-irritating Toxicity 0.000 abstract 1
- 229960002622 triacetin Drugs 0.000 abstract 1
- 238000005516 engineering process Methods 0.000 description 3
- 238000007689 inspection Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 2
- 210000003238 esophagus Anatomy 0.000 description 2
- 210000003800 pharynx Anatomy 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
- 206010011224 Cough Diseases 0.000 description 1
- 208000019505 Deglutition disease Diseases 0.000 description 1
- 241000167880 Hirundinidae Species 0.000 description 1
- 230000001079 digestive effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000002594 fluoroscopy Methods 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 210000004051 gastric juice Anatomy 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 210000002200 mouth mucosa Anatomy 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
Landscapes
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention discloses an aerogenesis capsule for barium meal radiography and a preparation method thereof. the aerogenesis capsule for barium meal radiography is prepared from raw materials as follows: 100g of aerogenesis powder and a capsule, wherein the capsule contains the following ingredients, 30g of gelatin, 20g of starch, 10g of mannitol, 1g of phosphatide, 1g of sodium alginate, 1g of sodium bicarbonate, 3g of vitamin E, 2g of glyceryl triacetate, 1g of polyethylene glycol and 30g of distilled water. The aerogenesis capsule for barium meal radiography is simple to prepare and convenient to use, is nonirritating to oral cavity, is very easy to dissolve in human body and is beneficial to barium meal radiography.
Description
Technical field
The present invention relates to a kind of Aerogenic capsule for Barium meal examination and preparation method thereof.
Background technology
In the time doing digestive canel barium meal contrast examination inspection, need meet with gas producing powder the inspection of gas barium double-contrast, when use, the gas producing powder of doses for subsequent use, pour in patient's mouth, go down with mixing in water for oral taking, after gas producing powder enters in Stomach in Patients, after seeing gastric juice, decompose generation gas, make the expansion of stomach organ, then remake barivm meal fluoroscopy (screem), to facilitate observation of use instrument, this shortcoming with mixing in water for oral taking gas producing powder is: gas producing powder is in the time entering patient oral cavity, oral mucosa is had to stronger stimulation, there is cough and choke phenomenon in patient, and dysphagia, patient agonizes, even cannot check, in addition, vertical gas powder is often trapped in oral cavity or is trapped in throat and esophagus, gas producing powder amount can not play one's part to the full, impact checks effect.
Summary of the invention
The technical problem to be solved in the present invention is to provide a kind of Aerogenic capsule for Barium meal examination and preparation method thereof.This is used for the Aerogenic capsule of Barium meal examination, not only makes simply, easy to use, swallows easily, and to oral cavity nonirritant, in human body, very easily dissolves, and is conducive to Barium meal examination.
For solving the problems of the technologies described above, the present invention adopts following technical scheme: the described Aerogenic capsule for Barium meal examination is made up of following raw material: gas producing powder and capsule, the parts by weight of described gas producing powder are: 100g gas producing powder, described capsule component and parts by weight proportioning are: 30g gelatin, 20g starch, 10g mannitol, 1g phospholipid, 1g sodium alginate, 1g sodium bicarbonate, 3g vitamin E, 2g triacetyl glycerine, 1g Polyethylene Glycol, 30g distilled water.
Another technical problem that the present invention will solve is to provide a kind of preparation method of the Aerogenic capsule for Barium meal examination.
For solving the problems of the technologies described above, the present invention adopts following technical scheme: comprise the following steps:
1) proportioning is extracted 20g starch, 10g mannitol, 1g phospholipid, 1g sodium alginate, 1g sodium bicarbonate grind into powder by weight, for subsequent use;
2) proportioning is extracted 30g gelatin, 30g distilled water by weight, 30g gelatin is put into the immersion of 30g distilled water its expansion is dissolved, and obtains half glue;
3) by step 1) powder and the step 2 of grinding) half glue prepared and 3g vitamin E, 2g triacetyl glycerine, 1g Polyethylene Glycol be together positioned in blender, is stirred to after being paste type object and stops, and obtains full glue;
4) take out the full glue preparing, be coated on smooth plate surface, make thickness even, then, with the temperature heating of 90 DEG C of left and right, make surface moisture evaporation, become and have certain toughness and elastic cushion compound;
5) by step 4) in cushion compound and 100g gas producing powder carry out manual compacting with pelleting mould, be pressed into the Aerogenic capsule of 100 parts of the present invention for Barium meal examination.
The beneficial effect of a kind of Aerogenic capsule for Barium meal examination of the present invention and preparation method thereof is: the sense of patient's no pain, under can disposable clothes, easy to operate, producing powder amount can all play a role, and all can not produce trapping phenomena in oral cavity, throat and esophagus.
Detailed description of the invention
For further understanding feature of the present invention, technological means and the specific purposes that reach, function, with detailed description of the invention, the present invention is described in further detail below.
Embodiment:
A kind of Aerogenic capsule for Barium meal examination of the present invention, the described Aerogenic capsule for Barium meal examination is made up of following raw material: gas producing powder and capsule, the parts by weight of described gas producing powder are: 100g gas producing powder, and described capsule component and parts by weight proportioning are: 30g gelatin, 20g starch, 10g mannitol, 1g phospholipid, 1g sodium alginate, 1g sodium bicarbonate, 3g vitamin E, 2g triacetyl glycerine, 1g Polyethylene Glycol, 30g distilled water;
The preparation method process of described a kind of Aerogenic capsule for Barium meal examination is as follows:
1) proportioning is extracted 20g starch, 10g mannitol, 1g phospholipid, 1g sodium alginate, 1g sodium bicarbonate grind into powder by weight, for subsequent use;
2) proportioning is extracted 30g gelatin, 30g distilled water by weight, 30g gelatin is put into the immersion of 30g distilled water its expansion is dissolved, and obtains half glue;
3) by step 1) powder and the step 2 of grinding) half glue prepared and 3g vitamin E, 2g triacetyl glycerine, 1g Polyethylene Glycol be together positioned in blender, is stirred to after being paste type object and stops, and obtains full glue;
4) take out the full glue preparing, be coated on smooth plate surface, make thickness even, then, with the temperature heating of 90 DEG C of left and right, make surface moisture evaporation, become and have certain toughness and elastic cushion compound;
5) by step 4) in cushion compound and 100g gas producing powder carry out manual compacting with pelleting mould, be pressed into the Aerogenic capsule of 100 parts of the present invention for Barium meal examination.
Experimental example:
Experimental subject: 100 have just been carried out the patient of canel barium meal contrast examination.
Experimental technique and time: 100 patients take respectively the present invention and carry out canel barium meal contrast examination for the second time for the Aerogenic capsule of Barium meal examination, record result, and contrast with primary canel barium meal contrast examination result.
Experimental result:
Wherein, sensation taste and mouthfeel have 100 people than general gas producing powder is acceptable, and have 57 manual inspections to find the minimal disease that does not check out for the first time.
After this patient of experimental group has been carried out to health investigation, do not found any side effect.
Experimental result is known thus, and the present invention, for the Aerogenic capsule of Barium meal examination, not only makes simply, easy to use, and to oral cavity nonirritant, in human body, very easily dissolves, and is conducive to Barium meal examination.
Below the present invention is described in detail, the above, be only the present invention's preferred embodiment, when not limiting the scope of the present invention, allly does impartial variation and modification according to the application's scope, all should still belong in covering scope of the present invention.
Claims (2)
1. the Aerogenic capsule for Barium meal examination, it is characterized in that: the described Aerogenic capsule for Barium meal examination is made up of following raw material: gas producing powder and capsule, the parts by weight of described gas producing powder are: 100g gas producing powder, described capsule component and parts by weight proportioning are: 30g gelatin, 20g starch, 10g mannitol, 1g phospholipid, 1g sodium alginate, 1g sodium bicarbonate, 3g vitamin E, 2g triacetyl glycerine, 1g Polyethylene Glycol, 30g distilled water.
2. a preparation method for the Aerogenic capsule for Barium meal examination as claimed in claim 1, is characterized in that: comprise the following steps:
1) proportioning is extracted 20g starch, 10g mannitol, 1g phospholipid, 1g sodium alginate, 1g sodium bicarbonate grind into powder by weight, for subsequent use;
2) proportioning is extracted 30g gelatin, 30g distilled water by weight, 30g gelatin is put into the immersion of 30g distilled water its expansion is dissolved, and obtains half glue;
3) by step 1) powder and the step 2 of grinding) half glue prepared and 3g vitamin E, 2g triacetyl glycerine, 1g Polyethylene Glycol be together positioned in blender, is stirred to after being paste type object and stops, and obtains full glue;
4) take out the full glue preparing, be coated on smooth plate surface, make thickness even, then, with the temperature heating of 90 DEG C of left and right, make surface moisture evaporation, become and have certain toughness and elastic cushion compound;
5) by step 4) in cushion compound and 100g gas producing powder carry out manual compacting with pelleting mould, be pressed into the Aerogenic capsule of 100 parts of the present invention for Barium meal examination.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410192786.1A CN103990150B (en) | 2014-05-08 | 2014-05-08 | A kind of Aerogenic capsule for Barium meal examination and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410192786.1A CN103990150B (en) | 2014-05-08 | 2014-05-08 | A kind of Aerogenic capsule for Barium meal examination and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103990150A true CN103990150A (en) | 2014-08-20 |
| CN103990150B CN103990150B (en) | 2016-06-22 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410192786.1A Active CN103990150B (en) | 2014-05-08 | 2014-05-08 | A kind of Aerogenic capsule for Barium meal examination and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103990150B (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1287861A (en) * | 2000-09-20 | 2001-03-21 | 温友信 | Aerogenic capsule for digestive canel barium meal contrast examination |
| CN103520727A (en) * | 2012-08-06 | 2014-01-22 | 济南圣泉唐和唐生物科技有限公司 | Capsule shell and preparation method thereof |
-
2014
- 2014-05-08 CN CN201410192786.1A patent/CN103990150B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1287861A (en) * | 2000-09-20 | 2001-03-21 | 温友信 | Aerogenic capsule for digestive canel barium meal contrast examination |
| CN103520727A (en) * | 2012-08-06 | 2014-01-22 | 济南圣泉唐和唐生物科技有限公司 | Capsule shell and preparation method thereof |
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| Publication number | Publication date |
|---|---|
| CN103990150B (en) | 2016-06-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C41 | Transfer of patent application or patent right or utility model | ||
| CB03 | Change of inventor or designer information |
Inventor after: Wang Qi Inventor after: Liu Guifang Inventor before: Wang Qi Inventor before: Han Jinhua Inventor before: Ren Zhenjie |
|
| COR | Change of bibliographic data | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20160513 Address after: Qingdao City, Shandong province 266000 four Road No. 127 Applicant after: Zhongxin Hospital, Qingdao Address before: Qingdao City, Shandong province 266000 four Road No. 127 Applicant before: Wang Qi |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20181112 Address after: 401120 3- 1, No. 11 Ring Road, Shuangfeng street, Yubei District, Chongqing. Patentee after: Chongqing Rongan Medical Equipment Co., Ltd. Address before: 266000 No. 127, four Liu Nan Road, Shibei District, Qingdao, Shandong Patentee before: Zhongxin Hospital, Qingdao |
|
| TR01 | Transfer of patent right | ||
| CP03 | Change of name, title or address |
Address after: 402760 No. 92 Donglin Avenue, Biquan Street, Bishan District, Chongqing (No. 52 Factory Building) Patentee after: Chongqing high tech Industry Research Institute Co., Ltd Address before: 401120 3- 1, No. 11 Ring Road, Shuangfeng street, Yubei District, Chongqing. Patentee before: CHONGQING RONGAN MEDICAL EQUIPMENT Co.,Ltd. |
|
| CP03 | Change of name, title or address |