CN104147215A - Compound traditional Chinese medicinal composition for treating mycoplasma pneumoniae of swine and preparation method thereof - Google Patents
Compound traditional Chinese medicinal composition for treating mycoplasma pneumoniae of swine and preparation method thereof Download PDFInfo
- Publication number
- CN104147215A CN104147215A CN201410444874.6A CN201410444874A CN104147215A CN 104147215 A CN104147215 A CN 104147215A CN 201410444874 A CN201410444874 A CN 201410444874A CN 104147215 A CN104147215 A CN 104147215A
- Authority
- CN
- China
- Prior art keywords
- parts
- mel
- herba houttuyniae
- swine
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention discloses a compound traditional Chinese medicinal composition for treating mycoplasma pneumoniae of a swine and a preparation method thereof. The compound traditional Chinese medicinal composition for treating mycoplasma pneumoniae of the swine is prepared from honey-fried aster, coltsfoot flower, dried tangerine or orange peel, ephedra, fresh cordate houttuynia, bitter almond, schisandra fruit, astragalus root and honey. Through clinical application, the compound traditional Chinese medicinal composition disclosed by the invention has the advantages of high recovery rate and significant effect in treatment.
Description
Technical field
The present invention relates to a kind of veterinary drug, is a kind of Chinese medicine composition that is used for the treatment of mycoplasmal pneumonia of swine exactly, with and preparation method thereof.
Background technology
Mycoplasmal pneumonia of swine (Mps) claim again mycoplasma pneumoniae of swine, epidemic swine pneumonia, that the one that caused by mycoplasma hyopneumoniae is chronic, contact respiratory infectious disease, main clinic symptoms is cough and asthma, cuts open the symmetry consolidation of examining the sharp leaf, lobus cardiacus and the lobus diaphragmaticus that are changed to lungs.According to incidence difference, be often divided into clinically acute, chronic, recessive three types.Acute is more common in newly-built pig farm and the new swinery infecting, common with piglet, in-pig and nursing sow.Suddenly, play is breathed heavily for affected pig morbidity, and spirit is depressed, and how absolutely useless appetite is, and body temperature is micro-high, and ventral breathing is obvious, and what have is sitting position of dog gesture, and cough number of times is few and low.Chronic type is many to be transformed by acute, is more common in feeder pig, growing and fattening pigs, the replacement gilt in old epidemic-stricken area.Clinical symptoms is long-term cough, when asthma, cough, is spastic, when temperature cataclysm and morning, evening and motion comparatively obvious after taking food, ventral breathing.Cause the resistance of body to decline during when feeding and management condition is bad, feed quality is inferior, in the situation of sombre humidity of pig house, improper ventilation, crowded and environmental condition cataclysm, cause mycoplasmal pneumonia of swine to occur or symptom is aggravated.This disease is worldwide widely current, and sickness rate is high, difficult to be eradicated, and causes the speed of growth of morbidity pig slow, and efficiency of feed utilization is low, and the feeding for fattening phase extends.
At present clinically the treatment of mycoplasmal pneumonia of swine is not also had to very good medicine, normal employing to boar and newborn piglet Pigs Inoculated mycoplasma pneumonia attenuated vaccine to improve Swinery immunity power clinically, but mycoplasma can change surface antigen and cause immunologic escape, a little less than causing immunity; In addition adopt the immunization route of thoracic cavity injection to be not easy to be accepted by general user, thereby be restricted on applying, so high infection rate kind pig farm is still taking western medicine as main, this sick the most frequently used Western medicine of current treatment is antibiotics, although therapeutic effect is obvious, application antibiotic therapy easily produces drug resistance, the drug residue time is long, expense is high, and has a strong impact on growth speed of pigs, causes raiser's economic loss.Therefore developing a kind of effective, residual low medicine for the treatment of mycoplasmal pneumonia of swine is the problem that this field scientific research technical staff needs solution badly.
Summary of the invention
The invention provides a kind of defect that overcomes prior art, for preventing and treating Chinese medicine composition of mycoplasmal pneumonia of swine and preparation method thereof.
The prescription of the herbal mixture compositions for the treatment of mycoplasmal pneumonia of swine of the present invention is:
Honey Radix Asteris 10-30 weight portion (as follows), Flos Farfarae 10-20 part, Pericarpium Citri Reticulatae 8-15 part, Herba Ephedrae 8-15 part, fresh Herba Houttuyniae (herb) 10-20 part, Semen Armeniacae Amarum 8-15 part, Fructus Schisandrae Chinensis 8-15 part, Radix Astragali 8-15 part, Mel 20-30 part.
The herbal mixture compositions best composition for the treatment of mycoplasmal pneumonia of swine of the present invention is: 20 parts of sweet Radix Asteriss, 15 parts of Flos Farfaraees, 10 parts of Pericarpium Citri Reticulataes, 10 parts, Herba Ephedrae, 15 parts of fresh Herba Houttuyniae (herb), 10 parts of Semen Armeniacae Amarums, 10 parts of Fructus Schisandrae Chinensis, 10 parts of the Radixs Astragali, 25 parts of Mel.
The preparation method of herbal mixture compositions of the present invention is:
A. take in proportion fresh Herba Houttuyniae, then pulverized evenly with pulverizer, make it to become the use such as even pasty state;
B. the each component decocting except Herba Houttuyniae, Mel taking is in proportion boiled, isolate the liquid after decoction;
C. under room temperature, isolated liquid is mixed homogeneously with pasty state Herba Houttuyniae and Mel.
The best preparation method of herbal mixture compositions of the present invention is that the each component except Herba Houttuyniae, Mel is decocted 2h by the water that adds 8 times of weight, retains filtrate; In medicinal residues, add again the decocting of 8 times of weight to boil 2h, merge twice decoction liquor, the medicinal liquid of the concentrated 1:1 of heating, 1kg Chinese medicine finally obtains 1L decoction liquor, then mixes with pasty state Herba Houttuyniae and Mel.
The pharmic function of this prescription feature and each component is as follows:
Honey Radix Asteris: pungent, bitter, sweet, tepor, enters lung meridian.There is nourishing the lung to keep the adverse QI downward, effect of preventing phlegm from forming and stopping coughing, for cough and asthma, chronic cough hemoptysis.Modern study shows that sweet Radix Asteris has resisting pathogenic microbes, eliminates the phlegm and antitumor action.
Flos Farfarae: acrid, sweet, warm, enter lung meridian.There is nourishing the lung to arrest cough, effect of the expectorant therapeutic method to keep the adverse QI flowing downwards.
Radix Asteris and Flos Farfarae are compatible, for clinical preventing phlegm from forming and stopping coughing to medicine.The pungent loose hardship of Radix Asteris is let out, and phlegm-dispelling functions is obvious, relatively preventing phlegm from forming and stopping coughing; The pungent temperature of Flos Farfarae, antitussive action is stronger, relatively lung qi dispersing cough-relieving, two medicine mutual reinforcements between are share, and can receive the merit of the expectorant therapeutic method to keep the adverse QI flowing downwards, the effect multiplication of cough-relieving.
Pericarpium Citri Reticulatae: the dry mature skin of rutaceae orange and variety thereof.Bitter, pungent, temperature, returns lung, spleen channel.There is regulating qi-flowing for strengthening spleen, the effect of drying dampness to eliminate phlegm, for fullness in the epigastrium and chest, lack of appetite and vomiting, the cards such as cough with copious phlegm.
Herba Ephedrae: pungent, micro-hardship, temperature, enters lung, urinary bladder channel.There is diaphoresis cold expelling, depressed lung-energy dispersing, effect of inducing diuresis to remove edema, for anemofrigid cold, uncomfortable in chest breathing with cough, cough and asthma, edema due to wind pathogen edema, the cards such as bronchial asthma.
Fresh Herba Houttuyniae: nature and flavor are pungent, cold, enter lung meridian.There is effect of heat-clearing and toxic substances removing, detumescence and apocenosis, antibacterial, antiviral, raising immunity of organisms.Research shows, Herba Houttuyniae fresh goods is compared with Herba Houttuyniae dry product, and the content of volatile oil is higher, and antiinflammatory, cough-relieving and antibacterial pharmacologically active are all better than dry product.Herba Houttuyniae fresh goods is squeezed the juice and has been avoided the reduction of traditional decocting process to its volatile oil content.
Semen Armeniacae Amarum: nature and flavor hardship, tepor, slightly poisonous, enter lung, large intestine channel.There is cloperastine and breathe heavily, effect of loosening bowel to relieve constipation.For cough and asthma, the cards such as dryness of the intestine constipation.
Fructus Schisandrae Chinensis: nature and flavor acid, temperature, enters lung, kidney, heart channel.There is the nourishing kidney of astringing the lung, the arresting sweating that promotes the production of body fluid, arresting seminal emission antidiarrheal, effect of mind tranquilizing and the heart calming.For chronic cough dyspnea due to deficiency, Tianjin wound is thirsty, spontaneous sweating, and emission due to deficiency of the kidney, spleen is suffered from a deficiency of the kidney and is rushed down, the cards such as palpitation and insomnia.
The Radix Astragali: nature and flavor are sweet, tepor, enters spleen, lung meridian.There is benefit and defend consolidating superficial resistance, tonifying Qi and lifting yang, promoting pus discharge and tissue regeneration strengthening, the effects such as inducing diuresis to remove edema.For weak, the anorexia and loose stool of the deficiency of vital energy, sinking of QI of middle-JIAO, deficiency of vital energy edema, the interior-heat card such as quench one's thirst.
Mel: nature and flavor are sweet, flat, return spleen, lung, large intestine channel.There is nourishing the lung to arrest cough, effect of loosening bowel to relieve constipation.For weakness of the spleen and stomach, cough due to deficiency of the lung, the cards such as cough caused by dryness dry pharynx.
Show that through clinical practice the present invention has advantages of that cure rate is high, evident in efficacy.
Detailed description of the invention
The present invention illustrates below in conjunction with embodiment.
In embodiments of the invention, the weight portion of ingredient used and each composition is:
20 parts of honey Radix Asteriss, 15 parts of Flos Farfaraees, 10 parts of Pericarpium Citri Reticulataes, 10 parts, Herba Ephedrae, 15 parts of fresh Herba Houttuyniae (herb), 10 parts of Semen Armeniacae Amarums, 10 parts of Fructus Schisandrae Chinensis, 10 parts of the Radixs Astragali, 25 parts of Mel.
Process for preparing medicine is:
1, accurately taking in proportion fresh Herba Houttuyniae, pulverized evenly with pulverizer, make it to become even pasty state, is A liquid.
2, accurately take in proportion each medicine except Herba Houttuyniae and Mel, be placed in container, add the water of 8 times of weight, decoct 2h, retain filtrate; In medicinal residues, add the decocting of 8 times of weight to boil 2h again, merge twice decoction liquor, the medicinal liquid (1kg Chinese medicine carries out concentration by the medicinal liquid obtaining after decocting, and finally obtains 1L decoction liquor) of the concentrated 1:1 of heating, puts to room temperature, is B liquid.
3, A, two kinds of solution of B and Mel are fully mixed, obtain the Chinese medicine composition of this invention.
The application of Chinese medicine composition of the present invention in preparation prevention and treatment mycoplasmal pneumonia of swine medicine
After having prepared according to described method with the medical material of aforementioned proportion, carry out following experiment:
491 of the piglets of individual raiser's natural occurrence, a stand a corner or dog shape sitting posture of sick pig breathed, and breathes, cough, and frequency of respiration increases severely, and is mainly and is ventral breathing, occurs that spasmodic cough even vomits seriously time.Disease pig spirit is depressed, is reluctant to walk about, and poor appetite, health is become thin, and slightly disorderly, happiness is sleeping is afraid of cold fur, and body temperature and appetite change not quite and growth retardation.Cuing open the visible lung of inspection has edema and edema due to disorder of QI in various degree, and the sharp leaf of two lungs and lobus cardiacus are symmetry, confluent bronchopneumonia pathological changes.Leading edge at sharp leaf, lobus cardiacus, middle leaf and the lobus diaphragmaticus of sick Pulmonis Sus domestica portion is meat sample or Macrobrachium nipponensis sample consolidation, and hilus pulumonis and the obvious enlargement of vertical phrenic lymph nodes, matter are hard, canescence, tangent plane succulence.By clinical symptoms, serodiagnosis, cut open the diagnostic methods such as inspection symptom, the inspection of x-ray fluoroscopy sheet and be diagnosed as the mycoplasma hyopneumoniae positive.Be divided at random three groups, use Drug therapy of the present invention for first group, by the administration of 1ml/ kg body weight drinking-water, 1 day 2 times, be used in conjunction 7, first group with control drug (ZHIKE SAN) treatment, by the administration of 1g/ kg body weight spice, 1 day 2 times, be used in conjunction 7, the 3rd group is blank group.
Result of use: sick pig cough, dyspneic symptom alleviate gradually, spirit takes a turn for the better, search for food, adopt water and also recover gradually normal, appetite obviously increases, after medication 7d, medicine group of the present invention is evident in efficacy to the mycoplasmal pneumonia of swine of natural occurrence, can alleviate rapidly the clinical symptoms of disease pig, has alleviated this symptom of dyspnea.Tested medicine is significant difference (P < 0.05) compared with control drug group curative effect.
Following table is the applicable cases contrast of medicine group of the present invention and medicine matched group (ZHIKE SAN) treatment mycoplasmal pneumonia of swine.
Show by result of the test: medicine of the present invention is suitable for the treatment of mycoplasmal pneumonia of swine.
Claims (4)
1. treat a herbal mixture compositions for mycoplasmal pneumonia of swine, it is characterized in that prescription is:
Honey Radix Asteris 10-30 weight portion (as follows), Flos Farfarae 10-20 part, Pericarpium Citri Reticulatae 8-15 part, Herba Ephedrae 8-15 part, fresh Herba Houttuyniae (herb) 10-20 part, Semen Armeniacae Amarum 8-15 part, Fructus Schisandrae Chinensis 8-15 part, Radix Astragali 8-15 part, Mel 20-30 part.
2. treat a herbal mixture compositions for mycoplasmal pneumonia of swine, it is characterized in that 20 parts of sweet Radix Asteriss, 15 parts of Flos Farfaraees, 10 parts of Pericarpium Citri Reticulataes, 10 parts, Herba Ephedrae, 15 parts of fresh Herba Houttuyniae (herb), 10 parts of Semen Armeniacae Amarums, 10 parts of Fructus Schisandrae Chinensis, 10 parts of the Radixs Astragali, 25 parts of Mel.
3. the preparation method of herbal mixture compositions described in claim 1 or 2, is characterized in that:
A. take in proportion fresh Herba Houttuyniae, then pulverized evenly with pulverizer, make it to become the use such as even pasty state;
B. the each component decocting except Herba Houttuyniae, Mel taking is in proportion boiled, isolate the liquid after decoction;
C. under room temperature, isolated liquid is mixed homogeneously with pasty state Herba Houttuyniae and Mel.
4. preparation method claimed in claim 3, is characterized in that: the each component except Herba Houttuyniae, Mel is decocted 2h by the water that adds 8 times of weight, retains filtrate; In medicinal residues, add again the decocting of 8 times of weight to boil 2h, merge twice decoction liquor, the medicinal liquid of the concentrated 1:1 of heating, then mix with pasty state Herba Houttuyniae and Mel.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410444874.6A CN104147215B (en) | 2014-09-03 | 2014-09-03 | A kind of herbal mixture composition and method of making the same for the treatment of porcine mycoplasmal pneumonia |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410444874.6A CN104147215B (en) | 2014-09-03 | 2014-09-03 | A kind of herbal mixture composition and method of making the same for the treatment of porcine mycoplasmal pneumonia |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104147215A true CN104147215A (en) | 2014-11-19 |
| CN104147215B CN104147215B (en) | 2016-05-11 |
Family
ID=51872979
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410444874.6A Expired - Fee Related CN104147215B (en) | 2014-09-03 | 2014-09-03 | A kind of herbal mixture composition and method of making the same for the treatment of porcine mycoplasmal pneumonia |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104147215B (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105031025A (en) * | 2015-09-09 | 2015-11-11 | 河南省帝一方生物制药有限公司 | Traditional Chinese medicine compound preparation for treating swine mycoplasmal pneumonia and preparation method thereof |
| CN105147802A (en) * | 2015-10-21 | 2015-12-16 | 大连民族大学 | Composition for treating swine mycoplasmal pneumonia and porcine contagious pleuropneumonia and preparation method |
| CN111686203A (en) * | 2020-06-23 | 2020-09-22 | 云南滇东猎人农林开发有限公司 | Composition for treating swine enzootic pneumonia and preparation method thereof |
-
2014
- 2014-09-03 CN CN201410444874.6A patent/CN104147215B/en not_active Expired - Fee Related
Non-Patent Citations (1)
| Title |
|---|
| 周军: "猪喘气病的中草药疗法", 《农村养殖技术》, no. 7, 15 April 2012 (2012-04-15), pages 35 * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105031025A (en) * | 2015-09-09 | 2015-11-11 | 河南省帝一方生物制药有限公司 | Traditional Chinese medicine compound preparation for treating swine mycoplasmal pneumonia and preparation method thereof |
| CN105031025B (en) * | 2015-09-09 | 2018-05-18 | 河南省帝一方生物制药有限公司 | Compound Chinese medicinal preparation for treating porcine mycoplasmal pneumonia and preparation method thereof |
| CN105147802A (en) * | 2015-10-21 | 2015-12-16 | 大连民族大学 | Composition for treating swine mycoplasmal pneumonia and porcine contagious pleuropneumonia and preparation method |
| CN105147802B (en) * | 2015-10-21 | 2018-10-02 | 大连民族大学 | Treat the composition and preparation method of porcine mycoplasmal, pig pleuropneumonia |
| CN111686203A (en) * | 2020-06-23 | 2020-09-22 | 云南滇东猎人农林开发有限公司 | Composition for treating swine enzootic pneumonia and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104147215B (en) | 2016-05-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103920051B (en) | A kind of medicine and preparation method for the treatment of infantile malnutrition | |
| CN102743657B (en) | Traditional Chinese medicine composition for preventing piglet dysentery and preparation method thereof | |
| CN104147215B (en) | A kind of herbal mixture composition and method of making the same for the treatment of porcine mycoplasmal pneumonia | |
| CN104027442A (en) | Traditional Chinese medicine preparation adopted in green and residual medicine free broiler cultivation, preparation method thereof and method for cultivating broilers by using traditional Chinese medicine preparation | |
| CN106822721A (en) | It is a kind of to treat traditional Chinese medicine compound oral liquid of swine enzootic pneumonia and preparation method thereof | |
| CN105148171A (en) | Weight-reducing medicine | |
| CN103989861A (en) | Chinese herbal medicine for swine enzootic pneumonia and production method thereof | |
| CN106668646A (en) | Traditional Chinese medicine for treating chicken egg yield reduction | |
| CN102836197B (en) | Lactation-promoting Chinese medicinal composition and preparation method thereof | |
| CN103638345B (en) | A kind of medicine for the treatment of insufficiency of lung-QI and preparation method thereof | |
| CN106511945A (en) | Medicine for treating insomnia and preparation method thereof | |
| CN101670009A (en) | Traditional Chinese medicine composite for treating pig inappetence and preparation method thereof | |
| CN104208328A (en) | Traditional Chinese medicine composition for preventing and treating infectious pleurisy of pigs and preparation method thereof | |
| CN104435644A (en) | Traditional Chinese medicine preparation for treating asthma as well as preparation method and application of traditional Chinese medicine preparation | |
| CN104274776A (en) | Traditional Chinese medicine for treatment of severe acne | |
| CN104083748A (en) | Traditional Chinese medicine formula for treating sour regurgitation caused by deficiency of gastric dynamics | |
| CN103656459B (en) | A kind of Chinese medicine for the treatment of deficiency of both lung and spleen syndrome cough | |
| CN104083490A (en) | Traditional Chinese medicine preparation for treating reflux esophagitis | |
| CN103784665A (en) | Chinese medicinal preparation for relieving irritable bowel syndrome and preparation method thereof | |
| CN103316302A (en) | Chinese medicine formula for treating angina pectoris | |
| CN103920078B (en) | A kind of medicine for the treatment of cough with asthma and preparation method thereof | |
| CN107375777A (en) | A kind of cough stopping oral liquor | |
| CN104353053A (en) | Traditional Chinese medicine composition for treating swine mycoplasmal pneumonia and preparation method thereof | |
| CN106620266A (en) | Traditional Chinese medicine composition for treating mycoplasmal pneumonia of swine | |
| CN106728645A (en) | A kind of Traditional Chinese medicine compound composition of domestic animal lactagogue |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160511 Termination date: 20200903 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |