CN105031025B - Compound Chinese medicinal preparation for treating porcine mycoplasmal pneumonia and preparation method thereof - Google Patents
Compound Chinese medicinal preparation for treating porcine mycoplasmal pneumonia and preparation method thereof Download PDFInfo
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Abstract
The invention belongs to a kind of for treating compound Chinese medicinal preparation of porcine mycoplasmal pneumonia and preparation method thereof, which is made of the raw material of following portions by weight：Windproof 10 20 parts, 5 15 parts of Radix Astragali, 5 10 parts of aster, 10 15 parts of coltsfoot, 10 15 parts of radix scrophulariae, 5 15 parts of moutan bark, 5 10 parts of Radix Glycyrrhizae, 10 15 parts of Asian puccoon, 10 20 parts of mulberry leaf, 10 20 parts of chrysanthemum.For treating the raw materials used abundance of compound Chinese medicinal preparation of porcine mycoplasmal pneumonia in the present invention, production technology is easy, into body after easily absorbed, and clinical administration is convenient, is suitble to group's administration, uses manpower and material resources sparingly；Compound Chinese medicinal preparation of the invention uses the combination principle of Chinese medicine monarch, and medicament contg is clear and definite, administration is accurate, quality controllable, carries out Chinese medicine treatment for porcine mycoplasmal pneumonia, safe and effective, noresidue has no drug resistance.
Description
Technical field
The invention belongs to field of traditional Chinese, and in particular to a kind of compound Chinese medicinal preparation for being used to treat porcine mycoplasmal pneumonia
And preparation method thereof.
Background technology
Porcine mycoplasmal pneumonia (Mycoplasmal pneumonia of Swine, MPS) is also known as swine enzootic pneumonia or pig place
Popular pneumonia is a kind of chronic, contact, the respiratory disease of non-lethality.The disease is popular in all over the world, to pig raising
Industry causes serious economic loss.The cardinal symptom of MPS is chronic no phlegm dry cough, pig growth retardation and feed conversion rate
It is low.In the case of not immune, MPS can infect the pig of all age group, including sucking pig and boar.At present, it is main both at home and abroad
Will be based on antibiotics, however as the lengthening of administration time, mycoplasma generates drug resistance to antibiotic.
The content of the invention
Easily is absorbed the object of the present invention is to provide one kind, convenient drug administration, safe and effective, and noresidue has no drug resistance
Compound Chinese medicinal preparation for treating porcine mycoplasmal pneumonia and preparation method thereof.
To achieve the above object, the technical solution adopted by the present invention is a kind of Chinese medicine for being used to treat porcine mycoplasmal pneumonia
Compound preparation is made of the raw material of following portions by weight：10-20 parts windproof, 5-15 parts of Radix Astragali, 5-10 parts of aster, coltsfoot 10-15
Part, 10-15 parts of radix scrophulariae, 5-15 parts of moutan bark, 5-10 parts of Radix Glycyrrhizae, 10-15 parts of Asian puccoon, 10-20 parts of mulberry leaf, 10-20 parts of chrysanthemum.
It is described to be made for treating the compound Chinese medicinal preparation of porcine mycoplasmal pneumonia using following methods：Each original is taken in proportion
Material, mixing are used to treat the compound Chinese medicinal preparation of porcine mycoplasmal pneumonia to obtain the final product.
It is windproof, acrid flavour, sweet, slightly warm in nature.Return bladder, lung, spleen, Liver Channel.With antipyretic, analgesia, antibacterial, anti-inflammatory, Hemorrhagic shock,
Enhancing is immunized, is calm, protecting stomach lining and have relexation to bronchial smooth muscle and generate the effect of relievining asthma.
Radix Astragali, the sweet temperature of property is distributed in lung channel, there is tonifying Qi and lifting yang, the function of invigorating qi for consolidating superficies.Modern medicine study shows that Radix Astragali has
Enhance body's immunity, liver protection, diuresis, anti-aging, resisting stress, decompression and wide antibacterial action, improve immune function.
To cough and asthma with the passing of time, shortness of breath and tired spirit, phlegm harmony have good effect in the powerless person of bringing up of lung.Chang Peiwu asters, coltsfoot etc., warm lung is fixed
The product of lung qi are good in asthma.Spleen gives birth to phlegm, and lung storage phlegm, so strong lunar with eliminating the phlegm, Radix Astragali tonifying Qi is so outstanding be apt to control the deficiency of vital energy.
Aster, composite family Aster, property is bitter, temperature.Warm lung, lower gas, dissolving phlegm, cough-relieving.With following pharmacological action：（1）Eliminating the phlegm
Effect；（2）Antibacterial action：Aster is in vitro to Escherichia coli, shigella dysenteriae, mycetozoan, typhoid bacillus, paratyphosum Bacterium, green
7 kinds of Gram-negative enteral pathogenic bacteria such as purulence bacillus and comma bacillus have certain inhibitory action；And there is confrontation pathogenic fungus
Effect；（3）Antivirus action：Infected by influenza has apparent inhibitory action；（4）Function of tumor inhibition.
Coltsfoot is the bud of composite family coltsfoot, and property and flavor of peppery and warm has moistening lung to lower qi, and resolving sputum stops the effect coughed.To respiratory system
Make apparatus cough-relieving, slightly eliminating the phlegm and antiasthmatic effect.《Drugization justice》：Coltsfoot, the main drop of bitter, gas is fragrant main to be dissipated, an object and it is dual-purpose
Have both.Therefore with entering lung, along the gas in lung, and the blood in clearing lung-heat.Cough with dyspnea specially is controlled, dysphoria with smothery sensation syndrome characterized by dyspnea, sputum is sticky, tears saliva raw meat
It is smelly, agent is wanted for all cards, the deficiency syndrome of the lung of such as coughing long is outstanding indispensable.
Radix scrophulariae（Classification system：Scrophularia ningpoensis Hemsl.）For Scrophulariaceae herbaceous plant.Heat-clearing is cool
Blood；Nourishing yin and lessening fire；Detoxicating and resolving a mass.Main warm heat disease heat and ying blood；Body heat；Polydipsia；Tongue is deep red；Send out spot；Hectic fever due to yin labor is coughed；Dysphoria not awake；
Tianjin hinder constipation；Mesh is puckery dim-sighted；Abscess of throat；Scrofula subcutaneous nodule；Skin sore.With analgesia, anti-inflammatory, antibacterial, immune-enhancing activity,
Antioxidation.
Moutan bark, it is bitter, pungent, it is slightly cold.The thoughts of returning home, liver and kidney channel.Clearing heat and cooling blood, it is promoting blood circulation and removing blood stasis.Modern study, contained paeonol
And its glucosides constituents in addition have anti-inflammatory effect；The methanolic extract of moutan bark has inhibition Platelet；Paeonol has
The effects that central inhibitory actions such as calmness, cooling, antipyretic, analgesia, spasmolysis and antiatherosclerosis, diuresis, antiulcer.
Radix Glycyrrhizae, gas is micro-, sweet and special.Sweet and neutral.The thoughts of returning home, spleen, lung, stomach.It invigorates the spleen and benefits qi, moistens the lung and relieve the cough, heat-clearing solution
Poison alleviates analgesic, mitigates pharmacological property.In weakness of the spleen and the stomach, shortness of breath and fatigue, palpitation and severe palpitation, cough phlegm is few, pathopyretic ulcer, medicine food poisoning,
Gastral cavity abdomen shoot, four limbs contraction pain.It is applied alone or can be used for asthma and cough with other medicines compatible use, it can also be used to reconcile some drugs
It is strong.Licoflavone, extract of licorice root and enoxolone have apparent antitussive effect；Phlegm-dispelling functions are also more significant.Radix Glycyrrhizae is also
There are anti-inflammatory, anti-allergic effects, the throat and tunica mucosa tracheae of inflammation can be protected.
Asian puccoon is Boraginaceae puccoon, bitter, cold.Enter percardium, Liver Channel.Cool blood, promoting blood circulation, heat-clearing, removing toxic substances.Control temperature
Hot spot rash, jaundice with damp-heat pathogen, purpura spit, are defeated in battle, hematuria, stranguria with turbid discharge, constipation with heat retention, burn, eczema, erysipelas, large carbuncle.With antibacterial,
Anti-inflammatory effect and it is antipyretic the effects that.
Mulberry leaf, it is bitter, sweet, it trembles with fear.Return lung, Liver Channel.Dispelling wind and heat from the body is clear liver and improved vision.For syndrome of superficies attacked by wind-heat, warm disease is from the beginning of scorching
Cough, red eye, swell pain, mesh are secretly dim-sighted etc..Chinese medicine mulberry leaf are gently evacuated clearly, and clearing lung-heat heat.Still there is cooling blood and hemostasis effect.
Chrysanthemum, pungent, sweet, bitter, micro- Huang.Return lung, Liver Channel.Dispelling wind and heat from the body is clear liver and improved vision.For syndrome of superficies attacked by wind-heat, warm disease from the beginning of,
Red eye, swell pain, mesh is secretly dim-sighted, vertigo.With resisting pathogenic microbes effect, refrigeration function, enhance body's hypoxia tolerance
Effect.
The beneficial effect comprise that：It is used to treat used in the compound Chinese medicinal preparation of porcine mycoplasmal pneumonia in the present invention
Raw material sources enrich, and production technology is easy, into body after easily absorbed, and clinical administration is convenient, is suitble to group's administration, section
Human-saving material resources；The compound Chinese medicinal preparation of the present invention uses the combination principle of Chinese medicine monarch, and medicament contg is clear and definite, administration is accurate
Really, it is quality controllable, Chinese medicine treatment is carried out for porcine mycoplasmal pneumonia, safe and effective, noresidue has no drug resistance.
Specific embodiment
With reference to specific embodiment, the invention will be further described, but protection scope of the present invention is without being limited thereto.
Embodiment 1
A kind of compound Chinese medicinal preparation for being used to treat porcine mycoplasmal pneumonia, is made of the raw material of following portions by weight：It is windproof
10 parts, 5 parts of Radix Astragali, 10 parts of aster, 15 parts of coltsfoot, 10 parts of radix scrophulariae, 5 parts of moutan bark, 5 parts of Radix Glycyrrhizae, 10 parts of Asian puccoon, 20 parts of mulberry leaf,
10 parts of chrysanthemum.
It is described to be made for treating the compound Chinese medicinal preparation of porcine mycoplasmal pneumonia using following methods：Each original is taken in proportion
Material, mixing are used to treat the compound Chinese medicinal preparation of porcine mycoplasmal pneumonia to obtain the final product.
Embodiment 2
A kind of compound Chinese medicinal preparation for being used to treat porcine mycoplasmal pneumonia, is made of the raw material of following portions by weight：It is windproof
20 parts, 15 parts of Radix Astragali, 5 parts of aster, 10 parts of coltsfoot, 15 parts of radix scrophulariae, 15 parts of moutan bark, 10 parts of Radix Glycyrrhizae, 15 parts of Asian puccoon, mulberry leaf 10
Part, 20 parts of chrysanthemum.
It is described to be made for treating the compound Chinese medicinal preparation of porcine mycoplasmal pneumonia using following methods：Each original is taken in proportion
Material, mixing are used to treat the compound Chinese medicinal preparation of porcine mycoplasmal pneumonia to obtain the final product.
Embodiment 3
A kind of compound Chinese medicinal preparation for being used to treat porcine mycoplasmal pneumonia, is made of the raw material of following portions by weight：It is windproof
15 parts, 10 parts of Radix Astragali, 8 parts of aster, 12 parts of coltsfoot, 13 parts of radix scrophulariae, 10 parts of moutan bark, 7 parts of Radix Glycyrrhizae, 12 parts of Asian puccoon, 15 parts of mulberry leaf,
16 parts of chrysanthemum.
It is described to be made for treating the compound Chinese medicinal preparation of porcine mycoplasmal pneumonia using following methods：Each original is taken in proportion
Material, mixing are used to treat the compound Chinese medicinal preparation of porcine mycoplasmal pneumonia to obtain the final product.
Application test
Selection is given treatment to during in May, -2015 in June, 2014 in the fattening of the doubtful porcine mycoplasmal pneumonia in Zhongmou County pig farm
The respondent of pig 50 as this time research topic, 50 growing and fattening pigs show spiritual depressed, loss of appetite, cough and asthma,
It is short of breath, there is bubble in auscultation lung.50 sick pigs row X-ray examination and Serological testing to this group, make a definite diagnosis 50 diseases
Pig meets the diagnostic criteria of porcine mycoplasmal pneumonia.According to measurement, the weight of 50 sick pigs of this group differs between 50~70kg,
The average weight of sick pig is（58.5±5.7）kg.50 pigs of this group are equally divided by test group and right using random manner
According to group, 2 groups of sick pig numbers are 25.
Control group treats 25 sick pigs of control group by the way of western medicine, how western gives 10% hydrochloric acid
Ring element soluble powder（Nanjing Longma animal pharmaceutical estate Co., Ltd）With 10% tylosin tartrate soluble powder（Jiangsu beast green for a long time
Medicine Co., Ltd）It is treated.Specifically usage and dosage is：Free water is administered, and adds doxycycline hydrochloride soluble per 1L water
Powder 0.5g and tylosin tartrate soluble powder 1g, continuous use 4 days.
Test group uses 25 diseases of the compound Chinese medicinal preparation to test group for being used to treat porcine mycoplasmal pneumonia of embodiment 1
Pig is treated, and specific usage and dosage is mixed feeding, per 1000g compound Chinese medicinal preparation spice 300kg, is used in conjunction 4 days.
The breath state of growing and fattening pigs, the clinical settings such as breathe, cough during observation treatment.After medication sick pig cough, asthma,
The symptoms such as abdominal respiration completely disappear, and the recoveries such as spirit, appetite are normal, and recidivist is not recovery from illness after drug withdrawal；Sick pig spirit, appetite
Recover normal, the substantially reduced symptoms such as cough, asthma are effective；Morbid pig clinical symptoms without significant change or even add after administration
Weight is dead, is invalid.The comparison of the therapeutic effect of control group and test group such as following table：
| Group | Number of cases | Recovery from illness | Effectively | It is invalid | Total effective rate |
| Test group | 25 | 16 | 8 | 1 | 96% |
| Control group | 25 | 10 | 7 | 8 | 68% |
As seen from the above table, two groups of sick pigs are after receiving to treat, and clinical symptoms and sign are improved and controlled, test group
The total effective rate of the treatment of sick pig（Recovery from illness+effectively）For 96%, the total effective rate of the treatment of control group sick pig is 68%, between two groups
Significant difference.Illustrate the present invention has porcine mycoplasmal pneumonia substantially for the compound Chinese medicinal preparation for the treatment of porcine mycoplasmal pneumonia
Effect.
Claims (2)
1. a kind of compound Chinese medicinal preparation for being used to treat porcine mycoplasmal pneumonia, which is characterized in that by the raw material of following portions by weight
Composition：10-20 parts windproof, 5-15 parts of Radix Astragali, 5-10 parts of aster, 10-15 parts of coltsfoot, 10-15 parts of radix scrophulariae, 5-15 parts of moutan bark,
5-10 parts of Radix Glycyrrhizae, 10-15 parts of Asian puccoon, 10-20 parts of mulberry leaf, 10-20 parts of chrysanthemum.
2. it is used to treat the preparation method of the compound Chinese medicinal preparation of porcine mycoplasmal pneumonia as described in claim 1, which is characterized in that
Comprise the following steps：Each raw material is taken in proportion, and mixing is used to treat the compound Chinese medicinal preparation of porcine mycoplasmal pneumonia to obtain the final product.
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Citations (3)
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|---|---|---|---|---|
| CN1108128A (en) * | 1994-09-29 | 1995-09-13 | 韦创新 | Chinese herbal medicine prepn. for curing pneumonia |
| CN104127558A (en) * | 2013-06-09 | 2014-11-05 | 河南金尔康动物药业有限公司 | Heat-clearing and detoxifying traditional Chinese medicine composition for livestock, and preparation method and application thereof |
| CN104147215A (en) * | 2014-09-03 | 2014-11-19 | 中国农业科学院兰州畜牧与兽药研究所 | Compound traditional Chinese medicinal composition for treating mycoplasma pneumoniae of swine and preparation method thereof |
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2015
- 2015-09-09 CN CN201510568986.7A patent/CN105031025B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1108128A (en) * | 1994-09-29 | 1995-09-13 | 韦创新 | Chinese herbal medicine prepn. for curing pneumonia |
| CN104127558A (en) * | 2013-06-09 | 2014-11-05 | 河南金尔康动物药业有限公司 | Heat-clearing and detoxifying traditional Chinese medicine composition for livestock, and preparation method and application thereof |
| CN104147215A (en) * | 2014-09-03 | 2014-11-19 | 中国农业科学院兰州畜牧与兽药研究所 | Compound traditional Chinese medicinal composition for treating mycoplasma pneumoniae of swine and preparation method thereof |
Non-Patent Citations (1)
| Title |
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| 浅谈猪支原体肺炎病的防治;安志民;《黑龙江畜牧兽医》;20100430;第100页 * |
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