CN104435644A - Traditional Chinese medicine preparation for treating asthma as well as preparation method and application of traditional Chinese medicine preparation - Google Patents
Traditional Chinese medicine preparation for treating asthma as well as preparation method and application of traditional Chinese medicine preparation Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
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- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8966—Fritillaria, e.g. checker lily or mission bells
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating asthma. Each dose of traditional Chinese medicine preparation comprises the following components by weight: 10-20g of poria cocos, 5-9g of apricot kernels, 10-15g of schisandra chinensis, 20-24g of radix glehniae from Liaoning, 20-30g of raw gypsum, 8-10g of perillaseed, 10-12g of raw cortex mori radicis, 3-5g of liquorice, 5-8g of fritillaria cirrhosa and 10-15g of pericarpium citri reticulatae. Meanwhile, the invention also discloses a preparation method and an application of the traditional Chinese medicine preparation. Through medicinal value and compatibility effect of various components in the traditional Chinese medicine prescription, the asthma, qi obstruction and deficiency of lung and vital energy can be effectively treated; and the traditional Chinese medicine preparation has the advantages of being good in curative effect, low in cost and convenient to take.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation and preparation method thereof and application, especially belong to Chinese medicine preparation for the treatment of asthma and preparation method thereof and application, belong to Chinese medicine formula and applied technical field.
Background technology
Asthma is lung deficiency of defensive qi, functional activity of QI being not smooth, the disease of impairment of dispersing and descending function of the lung, is respiratory system common disease, dyspnea, even opening mouth and lifting shoulder due to dyspnea, and flaring of nares can not equal a kind of disease crouched as feature.The primary disease cause of disease is complicated, the easy antiperspirant of the common aversion to wind of symptom, spiritlessness and weakness, and cough is panted, cause is due to lung qi and painstaking effort mutual dependence for existence, and the operation of blood depends on the promotion of gas, therefore insufficiency of lung-QI, recurrent exerbation, does not heal year in year out, during outbreak to resume treatment with the after treatment in later stage be important.
Summary of the invention
In order to solve the problem, the object of the present invention is to provide that a kind of side effect is little, good effect, expense are low, therapeutic effect is Chinese medicine preparation being used for the treatment of asthma and preparation method thereof and application significantly.
For solving the problems of the technologies described above, technical scheme of the present invention is:
The Chinese medicine preparation for the treatment of asthma, is characterized in that, the formula composition of every agent Chinese medicine preparation comprises following component and the quality of each component is respectively: Poria 10-20g; Semen Armeniacae Amarum 5-9g; Fructus Schisandrae Chinensis 10-15g; RADIX GLEHNIAE from Liaoning of China 20-24g; Gypsum Fibrosum 20-30g; Fructus Perillae 8-10g; Raw Cortex Mori 10-12g; Radix Glycyrrhizae 3-5g; Bulbus Fritillariae Cirrhosae 5-8g; Pericarpium Citri Reticulatae 10-15g.
Further, the Chinese medicine preparation for the treatment of asthma is preferably, and the formula composition of every agent Chinese medicine preparation comprises following component and the quality of each component is respectively: Poria 20g; Semen Armeniacae Amarum 9g; Fructus Schisandrae Chinensis 10g; RADIX GLEHNIAE from Liaoning of China 20g; Gypsum Fibrosum 30g; Fructus Perillae 8g; Raw Cortex Mori 10g; Radix Glycyrrhizae 3g; Bulbus Fritillariae Cirrhosae 5g; Pericarpium Citri Reticulatae 5g.
In addition, the described Chinese medicine preparation being used for the treatment of asthma, also comprises Semen Ziziphi Spinosae 10-15g; Exocarpium Citri Rubrum 10-12g.
And further, the Chinese medicine preparation for the treatment of asthma is preferably: the formula composition of every agent Chinese medicine preparation comprises following component and the quality of each component is respectively: Poria 20g; Semen Armeniacae Amarum 9g; Fructus Schisandrae Chinensis 10g; RADIX GLEHNIAE from Liaoning of China 24g; Gypsum Fibrosum 30g; Fructus Perillae 8g; Raw Cortex Mori 12g; Radix Glycyrrhizae 3g; Bulbus Fritillariae Cirrhosae 5g; Pericarpium Citri Reticulatae 10g; Semen Ziziphi Spinosae 10g; Exocarpium Citri Rubrum 10g.
Be used for the treatment of the manufacture method of the Chinese medicine preparation of asthma, it is characterized in that, after the described quality proportioning being used for the treatment of each component in the Chinese medicine preparation of asthma is mixed, carry out pulverizing and grind to form fine powder, cross 80-100 mesh sieve, then the fine powder after sieving is dropped in mixing and blending machine and fully mix, and for subsequent use according to the metering, distributing, packaging of every agent.
And the application of above-mentioned Chinese medicine preparation on preparation treatment asthmatic medicament, concrete instructions of taking is: by fine powder every day of every agent Chinese medicine preparation at twice, take after mixing it with water in half an hour ante cibum with warm water.
Beneficial effect of the present invention is: the present invention is by the medical value of each component in Chinese medicine preparation, and compatibility effect each other, can effective relieving asthma, and lung deficiency of defensive qi, functional activity of QI being not smooth, impairment of dispersing and descending function of the lung, has good effect, cost is low, the advantage of taking convenience.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention will be described in detail.
As follows for the pharmacology analysis situation of component in Chinese medicine preparation of the present invention:
Main component:
Poria: sweet in the mouth, light is flat; Eliminating dampness and diuresis; There is invigorating the spleen and regulating the stomach; Mind tranquilizing and the heart calming;
Fructus Schisandrae Chinensis: bitter in the mouth, sweet, warm in nature, return spleen, stomach warp; There is invigorating the spleen and benefiting QI, effect of dampness diuretic;
Pericarpium Citri Reticulatae; Bitter in the mouth, pungent, warm; For regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm, fullness in the epigastrium and chest, lack of appetite and vomiting;
Gypsum Fibrosum: acrid in the mouth, warm in nature; There is stopping nausea and vomiting by lowering the adverse flow of QI, stomach in gentleness, drying dampness to eliminate phlegm, effect of dissolving lump and resolving mass;
RADIX GLEHNIAE from Liaoning of China: property and flavor of peppery and warm.There is regulating the flow of QI to ease the stomach, dry cold-damp, effect of lung heat clearing blood stasis dispelling.Disease such as lung-heat insufficiency of the spleen grade can be controlled;
Semen Ziziphi Spinosae: arduous, has effects such as falling lung-heat, regulate the flow of vital energy.
Side's justice is analyzed:
Medicinal Poria; Effect that Semen Armeniacae Amarum, Fructus Schisandrae Chinensis, RADIX GLEHNIAE from Liaoning of China, Gypsum Fibrosum have clearing away phlegm to regulate the flow of vital energy, adds alluvial in Fructus Perillae, raw Cortex Mori, Radix Glycyrrhizae, Bulbus Fritillariae Cirrhosae, Pericarpium Citri Reticulatae removing body; Add Semen Ziziphi Spinosae, deficiency-heat that lung falls in Exocarpium Citri Rubrum, also can regulate the flow of vital energy and fall heat.
embodiment 1:
The component be used for the treatment of in the Chinese medicine preparation of asthma by described: Poria 20g; Semen Armeniacae Amarum 9g; Fructus Schisandrae Chinensis 10g; RADIX GLEHNIAE from Liaoning of China 24g; Gypsum Fibrosum 30g; Fructus Perillae 8g; Raw Cortex Mori 12g; Radix Glycyrrhizae 3g; Bulbus Fritillariae Cirrhosae 8g; Pericarpium Citri Reticulatae 10g, carries out pulverizing and grinds to form fine powder, mistake, 80 mesh sieves, is then dropped in mixing and blending machine by the fine powder after sieving and fully mixes, by fine powder every day of every agent Chinese medicine preparation at twice, take after mixing it with water in half an hour ante cibum with warm water.
embodiment 2:
The component be used for the treatment of in the Chinese medicine preparation of asthma by described: Poria 20g; Semen Armeniacae Amarum 9g; Fructus Schisandrae Chinensis 10g; RADIX GLEHNIAE from Liaoning of China 24g; Gypsum Fibrosum 20g; Fructus Perillae 8g; Raw Cortex Mori 12g; Radix Glycyrrhizae 5g; Bulbus Fritillariae Cirrhosae 5g; Pericarpium Citri Reticulatae 15g.After mixing, carry out pulverizing and grind to form fine powder, cross 90 mesh sieves, then the fine powder after sieving is dropped in mixing and blending machine and fully mix, by fine powder every day of every agent Chinese medicine preparation at twice, take after mixing it with water in half an hour ante cibum with warm water.
embodiment 3:
The component be used for the treatment of in the Chinese medicine preparation of asthma by described: Poria 10g; Semen Armeniacae Amarum 9g; Fructus Schisandrae Chinensis 15g; RADIX GLEHNIAE from Liaoning of China 20g; Gypsum Fibrosum 25g; Fructus Perillae 8g; Raw Cortex Mori 12g; Radix Glycyrrhizae 3g; Bulbus Fritillariae Cirrhosae 5g; Pericarpium Citri Reticulatae 15g.After mixing, carry out pulverizing and grind to form fine powder, cross 100 mesh sieves, then the fine powder after sieving is dropped in mixing and blending machine and fully mix, by fine powder every day of every agent Chinese medicine preparation at twice, take after mixing it with water in half an hour ante cibum with warm water.
embodiment 4:
The component be used for the treatment of in the Chinese medicine preparation of asthma by described: Poria 10g; Semen Armeniacae Amarum 9g; Fructus Schisandrae Chinensis 10g; RADIX GLEHNIAE from Liaoning of China 24g; Gypsum Fibrosum 20g; Fructus Perillae 8g; Raw Cortex Mori 12g; Radix Glycyrrhizae 3g; Bulbus Fritillariae Cirrhosae 5g; Pericarpium Citri Reticulatae 10g; Semen Ziziphi Spinosae 10g; After Exocarpium Citri Rubrum 12g mixing, carry out pulverizing and grind to form fine powder, cross 85 mesh sieves, then the fine powder after sieving is dropped in mixing and blending machine and fully mix, by fine powder every day of every agent Chinese medicine preparation at twice, take after mixing it with water in half an hour ante cibum with warm water.
embodiment 5:
The component be used for the treatment of in the Chinese medicine preparation of asthma by described: Poria 20g; Semen Armeniacae Amarum 5g; Fructus Schisandrae Chinensis 10g; RADIX GLEHNIAE from Liaoning of China 20g; Gypsum Fibrosum 30g; Fructus Perillae 8g; Raw Cortex Mori 12g; Radix Glycyrrhizae 3g; Bulbus Fritillariae Cirrhosae 5g; Pericarpium Citri Reticulatae 10g; Semen Ziziphi Spinosae 15g; Exocarpium Citri Rubrum 10g, carries out pulverizing and grinds to form fine powder, crosses 80 mesh sieves, is then dropped in mixing and blending machine by the fine powder after sieving and fully mixes, by fine powder every day of every agent Chinese medicine preparation at twice, take after mixing it with water in half an hour ante cibum with warm water.
embodiment 6:
The component be used for the treatment of in the Chinese medicine preparation of asthma by described: Poria 15g; Semen Armeniacae Amarum 9g; Fructus Schisandrae Chinensis 10g; RADIX GLEHNIAE from Liaoning of China 24g; Gypsum Fibrosum 25g; Fructus Perillae 8g; Raw Cortex Mori 12g; Radix Glycyrrhizae 5g; Bulbus Fritillariae Cirrhosae 5g; Pericarpium Citri Reticulatae 10g; Semen Ziziphi Spinosae 12g; Exocarpium Citri Rubrum 10g, carries out pulverizing and grinds to form fine powder, crosses 100 mesh sieves, is then dropped in mixing and blending machine by the fine powder after sieving and fully mixes, by fine powder every day of every agent Chinese medicine preparation at twice, take after mixing it with water in half an hour ante cibum with warm water.
For verifying the clinical effectiveness of invention formulation, carry out clinical experiment.
1, case selection standard:
All have lung deficiency of defensive qi, functional activity of QI being not smooth clinically, the rapid breathing caused by impairment of dispersing and descending function of the lung, sensation of oppression over the chest with shortness of breath, opening mouth and lifting shoulder due to dyspnea, and resting on the bedstead to sleep can not put down sleeping recurrent exerbation, does not heal year in year out, waits symptom all as the standard selecting case.
2, diagnostic criteria
Rapid breathing, sensation of oppression over the chest with shortness of breath, opening mouth and lifting shoulder due to dyspnea, resting on the bedstead to sleep can not put down sleeping recurrent exerbation, does not heal year in year out, and expectoration does not go out, purplish complexion, and breast gastral cavity painful abdominal mass is vexed, and stringy pulse is rapid.
3, therapeutic scheme
Treatment group takes the Chinese medicine preparation described in the embodiment of the present invention 2, every day potion, every day twice 7 days is a course for the treatment of, takes 3-5 the course for the treatment of, and matched group takes thin lung ball.
4, the course for the treatment of evaluation criteria:
Recovery from illness: symptom disappears without recurrence completely, without any discomfort symptom;
Effective: transference cure, without recurrence within 1 year;
Effective: symptom obviously alleviates, or partial symptoms disappears, and needs continual cure;
Invalid: symptom does not have any improvement, even there is the trend increased the weight of.
5, physical data
72 routine patients are out-patient.Be divided into treatment group and matched group at random.Treatment group 36 example, wherein, male 21 example, women 15 example, 31 ~ 59 years old age, average 44 years old; Matched group 36 example, male 20 example, women 16 example, 32 ~ 60 years old age, average 46 years old.In two groups, the course of disease is the longest 10 years, the shortest 1 year, average out to 6 years.Through statistical analysis, two groups of case-data there was no significant differences (P<0.05).
6, therapeutic effect:
Treatment group cures 18 examples, effective 8 examples, effective 6 examples, invalid 4 examples, and total effective rate is 88.9%; Matched group cure 8 example, effective 8 example, effective 10 example, invalid 10 example, total effective rate is 72.2%, treatment group total effective rate apparently higher than matched group, specifically in table 1.
A table 1 liang group therapeutic effect compares
| Group | Number of cases | Cure | Effective | Effectively | Invalid | Total effective rate (%) |
| Treatment group | 36 | 18 | 8 | 6 | 4 | 88.9 |
| Matched group | 36 | 8 | 8 | 10 | 10 | 72.2 |
The present invention is by the medical value of each component in Chinese medicine formula, and compatibility effect each other, effectively can treat asthma, lung deficiency of defensive qi, functional activity of QI being not smooth, the rapid breathing caused by impairment of dispersing and descending function of the lung, have good effect, cost is low, the advantage of taking convenience.
Above detailed description of the invention does not limit the present invention in any form, and every technical scheme obtained in the mode of equivalent replacement or equivalent transformation, all drops in protection scope of the present invention.
Claims (6)
1. be used for the treatment of the Chinese medicine preparation of asthma, it is characterized in that, the formula composition of every agent Chinese medicine preparation comprises following component and the quality of each component is respectively:
Poria 10-20g;
Semen Armeniacae Amarum 5-9g;
Fructus Schisandrae Chinensis 10-15g;
RADIX GLEHNIAE from Liaoning of China 20-24g;
Gypsum Fibrosum 20-30g;
Fructus Perillae 8-10g;
Raw Cortex Mori 10-12g;
Radix Glycyrrhizae 3-5g;
Bulbus Fritillariae Cirrhosae 5-8g;
Pericarpium Citri Reticulatae 10-15g.
2. the Chinese medicine preparation being used for the treatment of asthma according to claim 1, is characterized in that, the formula composition of every agent Chinese medicine preparation comprises following component and the quality of each component is respectively: Poria 20g; Semen Armeniacae Amarum 9g; Fructus Schisandrae Chinensis 10g; RADIX GLEHNIAE from Liaoning of China 24g; Gypsum Fibrosum 30g; Fructus Perillae 8g; Raw Cortex Mori 12g; Radix Glycyrrhizae 3g; Bulbus Fritillariae Cirrhosae 5g; Pericarpium Citri Reticulatae 10g.
3. the Chinese medicine preparation being used for the treatment of asthma according to claim 1 and 2, is characterized in that, also comprises Semen Ziziphi Spinosae (parched) 10-15g; Exocarpium Citri Rubrum 10-12g.
4. the Chinese medicine preparation being used for the treatment of asthma according to claim 1 and 2, is characterized in that, the formula composition of every agent Chinese medicine preparation comprises following component and the quality of each component is respectively: Poria 20g; Semen Armeniacae Amarum 9g; Fructus Schisandrae Chinensis 10g; RADIX GLEHNIAE from Liaoning of China 24g; Gypsum Fibrosum 30g; Fructus Perillae 8g; Raw Cortex Mori 12g; Radix Glycyrrhizae 3g; Bulbus Fritillariae Cirrhosae 5g; Pericarpium Citri Reticulatae 10g; Semen Ziziphi Spinosae 10g; Exocarpium Citri Rubrum 10g.
5. be used for the treatment of the manufacture method of the Chinese medicine preparation of asthma, it is characterized in that, after the described quality proportioning being used for the treatment of each component in the Chinese medicine preparation of asthma is mixed, carry out pulverizing and grind to form fine powder, cross 80-100 mesh sieve, then the fine powder after sieving is dropped in mixing and blending machine and fully mix, and for subsequent use according to the metering, distributing, packaging of every agent.
6. the application of Chinese medicine preparation according to claim 5 on preparation treatment asthmatic medicament.
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| CN107496745A (en) * | 2017-09-20 | 2017-12-22 | 河南中医药大学 | A kind of Chinese medicine composition for treating heat asthma |
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| WO2018232739A1 (en) * | 2017-06-23 | 2018-12-27 | 禹州市天源生物科技有限公司 | Pill for cough relief and phlegm removal, and preparation method thereof |
| CN107496745A (en) * | 2017-09-20 | 2017-12-22 | 河南中医药大学 | A kind of Chinese medicine composition for treating heat asthma |
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