CN103977149A

CN103977149A - Traditional Chinese medicinal preparation for treating cervicitis and preparation method

Info

Publication number: CN103977149A
Application number: CN201410240112.4A
Authority: CN
Inventors: 徐静
Original assignee: 徐静
Priority date: 2014-06-01
Filing date: 2014-06-01
Publication date: 2014-08-13

Abstract

The invention discloses a traditional Chinese medicinal preparation for treating cervicitis and a preparation method, and belongs to the field of a traditional Chinese medicine. Active ingredients of the traditional Chinese medicinal preparation contain the following raw materials: polygala root, chickweed, codonopsis lanceolata root, pyropolyporus formentarius teng, broadleaf holly leaves, dlichos sinensis, nakedflower beautyberry branchlet and leaves, tarella polyphylla, omosia henryi, sophora flower buds, Chinese juniper leaves, cortex albiziae, manaplant alhagi sweet secretion, mrinda officinalis, melastoma dodecandrum and wintercreeper. The traditional Chinese medicinal preparation disclosed by the invention, in which the medicinal materials selected are combined properly, is consistent with traditional Chinese medicine and modern medicine theories; moreover, the traditional Chinese medicinal preparation has functions of stimulating menstrual flow and checking vaginal discharge, clearing damp and expelling toxin, eliminating stagnation, dispelling wind and arresting itching; the traditional Chinese medicinal preparation has a significant curative effect on treating cervicitis, and is short in treatment course, rapid to take effect, convenient to take, low in cost, safe and reliable, free from any toxic and side effect, and free from recurrence after curing; the traditional Chinese medicinal preparation can achieve a purpose of treating both manifestation and root cause of disease, and is worthy of widely popularizing and using.

Description

A kind of Chinese medicine preparation and preparation method for the treatment of cervicitis

Affiliated technical field

The present invention relates to the field of Chinese medicines, relate in particular to a kind of Chinese medicine preparation and preparation method for the treatment of cervicitis.

Background technology

Cervicitis is the women of child-bearing age's commonly encountered diseases, has acute and chronic two kinds.Normal and the acute endometritis of acute cervicitis or acute vaginitis exist simultaneously, but common with chronic cervicitis, main manifestations is leucorrhoea grow in quantity, be sticky mucus or purulence mucus, sometimes can or accompany the blood streak with the blood streak, long-term chronic mechanical irritation is the main inducing that causes cervicitis, childbirth and artificial abortion etc. can damage cervix uteri, cause bacteria attack and form inflammation, or due to the direct infection of suppuration bacterium, or the acidity of high concentration or alkaline solution washing vagina, or intravaginal is placed or leaves over due to foreign body rejection; Chronic cervicitis more than childbirth, miscarriage or surgical injury cervix uteri after, pathogen is invaded and is caused infection, chronic cervicitis has multiple performance, as cervical erosion, cervical hypertrophy, cervical polyp, Naboth's cysts, endocervicitis etc., wherein common with cervical erosion.

Cervicitis is a kind of common gynaecopathia, and this disease mainly betides with it the women of childbearing age, and some people can go to seek medical advice less than hospital because fearing disease, but do like this, may cause more serious consequence.A lot of friends women have suffered from cervical polyp, but the last because deterioration of the state of an illness, harm and die.The function that cervicitis impact is bred mainly will be seen the order of severity of cervicitis, and slight cervicitis does not have too much influence to fertility, if treat not in time, serious is the generation that very likely causes female acyesis.Cervicitis, except meeting has influence on women's pregnancy, also may cause women to miscarry.

The Western medicine for the treatment of cervicitis is a lot of at present, but most drug therapeutic effect is poor, and also has the shortcomings such as treatment cost is high, side effect is large, all cannot fundamentally treat, and curative effect is general, has certain side effect, cannot reach the object for the treatment of both the principal and secondary aspects of a disease, when serious, even affect patient health.

Summary of the invention

The invention provides a kind of Chinese medicine preparation and preparation method for the treatment of cervicitis; The selected medical material compatibility of Chinese medicine preparation of the present invention is suitable, meets Chinese medicine and pharmacy and modern medicine theory, and has the effect of the leukorrhagia stopping of stimulating the menstrual flow, eliminating dampness and expelling toxin, repercussive eliminating stagnation, dispelling wind for relieving itching, treatment cervicitis is had to significant curative effect, short treating period, instant effect, taking convenience, with low cost, safe and reliable, without any side effects, non-relapse after healing, can reach the object for the treatment of both the principal and secondary aspects of a disease, application should be widely promoted.

For achieving the above object, technical scheme of the present invention is implemented as follows:

Treat a Chinese medicine preparation for cervicitis, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:

Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:

Treat a preparation method for the Chinese medicine preparation of cervicitis, comprise following processing step:

(1) Radix polygalae arillatae, Fomes Fomentarius, Folium Ilicis, Semen vignae sinensis, Folium et cacumen sabinae chinensis, Cortex Albiziae, Mel Alhagi, Radix Morindae Officinalis and Herba Melastomatis Dodecandri are cleaned, put into container, add the distilled water of 8～10 times of amounts, soak after 5～6 hours, boil 3～4 hours, extract; Again add 6～8 times of amount distilled water, boil 2～3 hours, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, be condensed into the thick paste that at 60 ℃, relative density is 1.10～1.13, standby;

(2) Herba stellariae mediae is cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice standby;

(3) wheel blade Radix Codonopsis root, Folium et Ramulus Callicarpae nudiflorae, Herba tiarellae polyphyllae, Lignum pterocarpi indici and Caulis Seu Folium Euonymi Fortunei are cleaned, immersed 80% the alcohol solution dipping 1～2 hour of 5 times of amounts, heating extraction 3 hours, reclaim ethanol, filter, obtain filtrate, the thick paste that at 65 ℃ of simmer down tos, relative density is 1.12～1.16, standby;

(4) by Flos Sophorae Immaturus decontamination, put into pot, slow fire is fried to micro-yellow, and taking-up cools, and is placed in mortar and grinds into powder, crosses 200 order fine powders, standby;

(5) above-mentioned steps (1)～(4) prepared thick paste, juice and fine powder are mixed, make capsule, obtain the Chinese medicine preparation for the treatment of cervicitis of the present invention.

The property of medicine of the present invention's Chinese medicine used is as follows:

Radix polygalae arillatae: sweet in the mouth, warm in nature.Inrigorating qi and promoting blood circulation, expelling wind and removing dampness.For pulmonary tuberculosis, puerperal asthenia, menoxenia, leucorrhea, uterine prolapse, hepatitis, rheumatalgia, traumatic injury.

Herba stellariae mediae: sweet in the mouth, acid, cool in nature.Heat-clearing and toxic substances removing, blood-activating analgetic, lactogenic.For enteritis, dysentery, hepatitis, appendicitis, postnatal blood stasis stomachache, uterine contraction pain, toothache, early whitening of hair, agalactia, mastitis, traumatic injury, sore swollen toxin.< < Bencao Tujing > > carries: " wipe tooth a surname and reveal, dry work is not useful.”

Wheel blade Radix Codonopsis root: sweet in the mouth, pungent, property is flat; Return lung, liver, spleen, large intestine channel.Tonify deficiency profit, lactogenesis evacuation of pus, detoxification sore treatment.Cure mainly physical weakness, hypogalactia, pulmonary abscess, mastitis, the diseases such as lymphoid tuberculosis.< < Zhiwu Mingshi Tukao > > carries: " suppurative mastitis juice, tonifying YANG road.”

Fomes Fomentarius: mildly bitter flavor, property is flat.Removing food stagnancy, blood stasis dispelling, anticancer.Cure mainly food stagnation, the esophageal carcinoma, gastric cancer, uterus carcinoma.Pharmacological evaluation shows, Fomes Fomentarius can significantly improve the tolerance of experiment mice hypobaric hypoxia, extends its time-to-live, has the effect of resisting fatigue, high temperature resistance; And flow velocity, the fluidised form that can affect anoxia body Mesentery microcirculation, have improvement effect to microcirculation.

Folium Ilicis: sweet in the mouth, hardship; Enter liver, lung, stomach warp.Loose wind heat, refresh oneself, relieving thirst and restlessness.Control headache, toothache, conjunctival congestion, Ting ear, calentura excessive thirst, dysentery.< < Chinese medicine voluminous dictionary > > carries: " loose liver-wind, refresh oneself, controls tinnitus, deafness, Ting discharging ear, the arteries and veins of invigorating blood circulation, cool uterus.”

Semen vignae sinensis: sweet in the mouth, property is flat; Enter spleen, kidney channel.Strengthening spleen, tonifying kidney.Cure mainly weakness of the spleen and stomach, dysentery, tells contraryly, quench one's thirst, and seminal emission, leucorrhea, nebulousurine, frequent micturition.< < detailed outline > > carries: " QI invigorating in reason, tonifying kidney and promoting digestion, and the five internal organs adjust battalion to defend, spermatogenesis marrow.Only quench one's thirst, tell contraryly, let out dysentery, frequent micturition, separates the big poison of Mus.”

Folium et Ramulus Callicarpae nudiflorae: micro-hardship, property is flat.Hemostasis and anti-inflammation, stasis-dispelling and pain-killing.Control hemorrhage that pneumorrhagia type leptospirosis, pulmonary tuberculosis, lung abscess, lobar pneumonia etc. cause, the upper gastrointestinal hemorrhage that Peptic Ulcers etc. cause, thrombocytopenic purpura, hematuria, wound hemorrhage, influenza, burn, suppurative skin ulcer, cervical erosion, traumatic injury, rheumatalgia.The < < record > > that gathers medicinal herbs in the south of the Five Ridges carries: " decoct washing traumatic injury wound, can eliminating blood stasis to promote regeneration of blood.As swelling due to wind, leaf is decocted to washing, get its stalk and lean pork decoction, can wind dispelling detumescence.”

Herba tiarellae polyphyllae: bitter in the mouth, cold in nature, nontoxic; Return lung meridian.Heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain.Main furuncle, nameless gall, cough, asthma, hepatitis, traumatic injury.< < Sichuan WuLong's medicine is planted figure will > > and is carried: " control deafness, asthma.”

Lignum pterocarpi indici: acrid in the mouth, warm in nature, poisonous.Blood circulation promoting and blood stasis dispelling, the detumescence of dispeling the wind.For traumatic injury, lumbar muscle strain, rheumatic arthritis, puerperal blood stasis pain, leucorrhea, mumps, filaricide, fracture is controlled in root bark external, burn and scald is controlled in leaf external.

The Flos Sophorae Immaturus: sweet in the mouth, flat, cold; Enter liver, large intestine channel.Cooling blood for hemostasis, liver heat removing pathogenic fire reducing.Cure mainly discharging fresh blood stool, hemorrhoidal bleeding, hematuria, stranguria with blood, metrorrhagia, blood, dysentery with red and white feces, conjunctival congestion, sore, the diseases such as hypertension.< < detailed outline > > carries, and " fries fragrant frequently chewing, controls aphonia and sore throat.Treat and spit blood again, nosebleed, metrorrhagia and metrostaxis ".

Folium et cacumen sabinae chinensis: acrid in the mouth, hardship, warm in nature, mild toxicity.Expelling wind and cold, promoting blood circulation and detoxication.Control anemofrigid cold, rheumatic arthritis, urticaria, toxic swelling from the beginning of.< < Fujian traditional herbal medicine > > carries: " parasite killing dirt eliminating, powder detoxifcation.Control urticaria, scleroma toxic swelling from the beginning of.”

Cortex Albiziae: sweet in the mouth, property is flat; GUIXIN, liver, lung meridian.Resolving stagnation for tranquilization, promoting blood circulation and detumescence.For irritability, melancholy insomnia, lung abscess skin ulcer is swollen, falls and flutters the pain of injury.< < conventional Chinese herbal medicine handbook > > in Nanchuan carries: " control that the motive is restless, insomnia and clonic spasm of the muscle.”

Mel Alhagi: sweet in the mouth, acid, property is flat; GUIXIN, lung, spleen, small intestinal, kidney channel.Convergence, astringing intestine to stop diarrhea, pain relieving.Main dysentery, diarrhoea, abdominal distention, hectic fever due to YIN-deficiency excessive thirst, headache, toothache.< < Bencao Shiyi > > carries: " main bone heat, phlegmatic cough, the sudden and violent hematochezia of dysentery, appetizing, quenches the thirst, relieving restlessness.”

Radix Morindae Officinalis: sweet in the mouth, pungent, slightly warm in nature; Return kidney, Liver Channel.Kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.For impotence and seminal emission, cold womb is infertile, menoxenia, and few abdomen cold type of pain, rheumatic arthralgia, muscles and bones flaccidity is soft.

Herba Melastomatis Dodecandri: sweet in the mouth, puckery, property is flat; Enter liver,kidney,spleen, lung four warps.Heat-clearing and toxic substances removing, expelling wind and removing dampness, tonifying blood and arresting bleeding.Be used for preventing epidemic cerebrospinal meningitis, enteritis, dysentery, lung abscess, pelvic inflammatory disease, metrorrhagia, anemia, leucorrhea, lumbago and skelalgia, rheumatic ostalgia, traumatic hemorrhage, venom.

Caulis Seu Folium Euonymi Fortunei: bitter in the mouth, sweet, warm in nature.Dissipating blood stasis hemostasis, relaxing muscles and tendons and activating QI and blood in the collateral.For spitting of blood, menoxenia, dysfunctional uterine hemorrhage, rheumatic arthralgia; Traumatic injury is controlled in external, fracture, wound hemorrhage.< < Tianmu Mountains of Zhejiang Province medicine is planted will > > and is carried: " promoting flow of QI and blood.Control lumbocrural pain, joint aches.”

The present invention compared with prior art, has following beneficial effect:

The selected medical material compatibility of Chinese medicine preparation of the present invention is suitable, meets Chinese medicine and pharmacy and modern medicine theory, and has the effect of the leukorrhagia stopping of stimulating the menstrual flow, eliminating dampness and expelling toxin, repercussive eliminating stagnation, dispelling wind for relieving itching, treatment cervicitis is had to significant curative effect, short treating period, instant effect, taking convenience, with low cost, safe and reliable, without any side effects, non-relapse after healing, can reach the object for the treatment of both the principal and secondary aspects of a disease, application should be widely promoted.

The specific embodiment

Below in conjunction with specific embodiment, the present invention is further elaborated.

Embodiment 1

The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:

Usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 2 (every 0.5g), after meal warm water delivery services; Within 6 days, be 1 course for the treatment of, can fully recover 2～3 courses for the treatment of, and the person of being in a bad way follows the doctor's advice and drinks the amount of adding.

Embodiment 2

Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.

Embodiment 3

6

Embodiment 4

Embodiment 5

Clinical data:

1, case selection:

As the Chinese medicine preparation for the treatment of cervicitis, select the routine clinical observation of virus in patients with cervicitis 862 make a definite diagnosis, patient to be divided at random two groups for the treatment of group and matched groups, treatment group 431 examples, 25～54 years old age, 39.5 years old mean age, average course of disease 1～6 year; Matched group 431 examples, 26～53 years old age, 39.5 years old mean age, average course of disease 1～5 year.

The course of disease, the degrees of symptoms for the treatment of group and two groups of cases of matched group are basically identical, without significant difference, have comparability.

2, medicament selection:

Treatment group is taken Chinese medicine preparation of the present invention, oral, every day 2 times, each 1 time sooner or later, each 2 (every 0.5g), after meal warm water delivery services; Within 6 days, be 1 course for the treatment of, can fully recover 2～3 courses for the treatment of, and the person of being in a bad way follows the doctor's advice and drinks the amount of adding.

7

Matched group is taken primordial QI reinforcing capsule, oral, one time 4,2 times on the one, the course for the treatment of is depending on the state of an illness.

3, efficacy determination:

(1) cure: above-mentioned symptom all disappears, and physical recovery is normal.

(2) effective: above-mentioned symptom obviously alleviates, health takes a turn for the better to some extent.

(3) effective: above-mentioned symptom alleviates to some extent, and health is clearly better.

(4) invalid: by treating rear above-mentioned symptom without alleviating or increasing the weight of.

4, result:

Above result demonstration, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.

Model case is given an example:

1, turn round and look at certain, female, 26 years old, people from Chongwen District, Beijing.Patient has the symptoms such as leucorrhea abnormal, pudendal pruritus, menoxenia at ordinary times, significantly not uncomfortable, finds to suffer from cervicitis when doing gynecologial examination, uses several different methods treatment, has no improvement.Take Chinese medicine preparation treatment of the present invention, take after 1 course for the treatment of, symptom disappears to some extent; Take after 1 course for the treatment of, symptom obviously disappears, and leucorrhea is normal; Continue to take after 1 course for the treatment of, through examination in hospital cervicitis, fully recover.

2, marquis, female, 30 years old, people from Hebei District, Tianjin.Patient is uncomfortable because of lower abdomen, removes hospital admission, finds on inspection intrauterine inflammation, and doctor recommends to take Chinese medicine preparation treatment of the present invention, takes after 1 course for the treatment of, checks, inflammation disappears substantially, takes after the 2nd course for the treatment of, checks that inflammation disappears, and follows up a case by regular visits to so far not recurrence.

3, Shao, female, 28 years old, people from Yu Zhong district, Chongqing.Patient suffers from cervicitis 1 year, through many hospitalizes, does not heal, rear to our hospital, takes Chinese medicine preparation treatment of the present invention, takes after 1 course for the treatment of, and symptom disappears to some extent, takes after 2 courses for the treatment of, cures, and follows up a case by regular visits to without recurrence after half a year.

4, the Meng, female, 34 years old, people from Liaoyuan, Jilin.Patient suffers from cervicitis, goes to too much home's hospitalize, all has no improvement, through friend, introduces, rear to our hospital, gives Chinese medicine preparation treatment of the present invention, takes after 1 course for the treatment of, and inflammation is clearly better, and takes after the 2nd course for the treatment of, cure, 1 year afterwards check do not recur.

5, dragon certain, female, 42 years old, Distributions in Liaocheng of Shandong Province people.Patient suffers from cervicitis, and leucorrhea is many especially, and summer is trousers wet through and through usually, that stench taste also always be can't get rid of, used multiple Drug therapy, therapeutic effect is general, rear to our hospital, take Chinese medicine preparation treatment of the present invention, take after 1 course for the treatment of, symptom takes a turn for the better to some extent, continues to take Chinese medicine preparation of the present invention after 1 course for the treatment of, recovery from illness, follows up a case by regular visits to after half a year without recurrence.

6, ten thousand certain, female, 48 years old, people from Wuhu.The conscious waist and sacrum pain of patient, the sense of hypogastric region falling inflation, increases the weight of during sexual life and has hemorrhage on a small quantity, the leucorrhea mucus shape that is creamy white, goes local gynaecologic hospital inspection, and cloudy super visible cervix uteri has erosion in various degree, hypertrophy, cervix uteri mouth has a large amount of purulent secretions, is diagnosed as cervicitis, through taking Chinese medicine preparation treatment of the present invention, take after 1 course for the treatment of pain relief, leucorrhea reduces, take after 2 courses for the treatment of, the further consultation of Zai Qu hospital, cloudy super inspection, cervicitis are fully recovered.

Claims

1. a Chinese medicine preparation for the treatment of cervicitis, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:

19～43 parts of 19～43 parts of Fomes Fomentarius of 20～44 parts of wheel blade Radix Codonopsis roots of 22～46 parts of Herba stellariae mediaes of Radix polygalae arillatae

16～40 parts of 17～41 parts of Herba tiarellae polyphyllaes of 17～41 parts of Folium et Ramulus Callicarpae nudiflorae of 18～42 portions of Semen vignae sinensiss of Folium Ilicis

13～37 parts of 13～37 portions of Cortex Albiziaes of 14～38 parts of Folium et cacumen sabinae chinensis of 16～40 portions of Flos Sophorae Immaturus of Lignum pterocarpi indici

7～31 parts of 10～34 portions of Caulis Seu Folium Euonymi Fortuneis of 10～34 parts of Herba Melastomatis Dodecandri of 11～35 parts of Radix Morindae Officinaliss of Mel Alhagi.

2. a kind of Chinese medicine preparation for the treatment of cervicitis according to claim 1, is characterized in that: the raw material of making described Chinese medicine preparation effective ingredient forms and parts by weight are:

23～39 parts of 23～39 parts of Fomes Fomentarius of 24～40 parts of wheel blade Radix Codonopsis roots of 26～42 parts of Herba stellariae mediaes of Radix polygalae arillatae

20～36 parts of 21～37 parts of Herba tiarellae polyphyllaes of 21～37 parts of Folium et Ramulus Callicarpae nudiflorae of 22～38 portions of Semen vignae sinensiss of Folium Ilicis

17～33 parts of 17～33 portions of Cortex Albiziaes of 18～34 parts of Folium et cacumen sabinae chinensis of 20～36 portions of Flos Sophorae Immaturus of Lignum pterocarpi indici

11～27 parts of 14～30 portions of Caulis Seu Folium Euonymi Fortuneis of 14～30 parts of Herba Melastomatis Dodecandri of 15～31 parts of Radix Morindae Officinaliss of Mel Alhagi.

3. a kind of Chinese medicine preparation for the treatment of cervicitis according to claim 1, is characterized in that: the raw material of making described Chinese medicine preparation effective ingredient forms and parts by weight are:

27～35 parts of 27～35 parts of Fomes Fomentarius of 28～36 parts of wheel blade Radix Codonopsis roots of 30～38 parts of Herba stellariae mediaes of Radix polygalae arillatae

24～32 parts of 25～33 parts of Herba tiarellae polyphyllaes of 25～33 parts of Folium et Ramulus Callicarpae nudiflorae of 26～34 portions of Semen vignae sinensiss of Folium Ilicis

21～29 parts of 21～29 portions of Cortex Albiziaes of 22～30 parts of Folium et cacumen sabinae chinensis of 24～32 portions of Flos Sophorae Immaturus of Lignum pterocarpi indici

15～23 parts of 18～26 portions of Caulis Seu Folium Euonymi Fortuneis of 18～26 parts of Herba Melastomatis Dodecandri of 19～27 parts of Radix Morindae Officinaliss of Mel Alhagi.

4. a kind of Chinese medicine preparation for the treatment of cervicitis according to claim 1, is characterized in that: the raw material of making described Chinese medicine preparation effective ingredient forms and parts by weight are:

31 parts of 31 parts of Fomes Fomentarius of 32 parts of wheel blade Radix Codonopsis roots of 34 parts of Herba stellariae mediaes of Radix polygalae arillatae

28 parts of 29 parts of Herba tiarellae polyphyllaes of 29 parts of Folium et Ramulus Callicarpae nudiflorae of 30 portions of Semen vignae sinensiss of Folium Ilicis

25 parts of 25 portions of Cortex Albiziaes of 26 parts of Folium et cacumen sabinae chinensis of 28 portions of Flos Sophorae Immaturus of Lignum pterocarpi indici

19 parts of 22 portions of Caulis Seu Folium Euonymi Fortuneis of 22 parts of Herba Melastomatis Dodecandri of 23 parts of Radix Morindae Officinaliss of Mel Alhagi.

5. as described in claim 1～4 any one, treat a preparation method for the Chinese medicine preparation of cervicitis, it is characterized in that: comprise following processing step: