CN104857096A - Traditional Chinese medicine composition for treating cervicitis - Google Patents
Traditional Chinese medicine composition for treating cervicitis Download PDFInfo
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- CN104857096A CN104857096A CN201510276661.1A CN201510276661A CN104857096A CN 104857096 A CN104857096 A CN 104857096A CN 201510276661 A CN201510276661 A CN 201510276661A CN 104857096 A CN104857096 A CN 104857096A
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Abstract
The invention belongs to the field of traditional Chinese medicines, and provides a traditional Chinese medicine composition for treating cervicitis. The traditional Chinese medicine composition is prepared from the following raw materials: 20 parts of Chinese catalpa, 16 parts of thalictrum foliolosum, 20 parts of comanthosphace ningpoensis, 18 parts of java marsh pennywort, 14 parts of tiarella polyphylla, 16 parts of bidens tripartita roots, 20 parts of linearleaf vetchling and 18 parts of achnatherum inebrians. The traditional Chinese medicine composition can be used for treating cervicitis.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine preparation, be specifically related to a kind of Chinese medicine composition being used for the treatment of cervicitis and its preparation method and application.
Background technology
Cervicitis comprises vaginal part of cervix inflammation and cervical canal mucosal inflammation.Because cervical canal portio vaginalis squamous epithelial cancer continues mutually with vagina squamous, colpitis all can cause vaginal part of cervix inflammation.Because cervical canal mucosal epithelium is simple columnar epithelium, anti-infection ability is poor, easily infects.Because sickness rate is high, for this reason, be bursting to and develop the needs that more medicines for the treatment of cervicitis safely and effectively meet clinical treatment.
Summary of the invention
In order to solve the problem, the object of the present invention is to provide a kind of Chinese medicine preparation for the treatment of cervicitis disease.In order to reach this object, adopt following technical scheme:
Technical scheme: a kind of Chinese medicine composition being used for the treatment of cervicitis, the active component contained by it is extracted by following weight crude drug and is prepared from: Folium catalpae bungei 20 parts, leaf Radix et Rhizoma Thalictri 16 parts, Herba Elsholtziae Ciliatae 20 parts, Herba Hydrocotylis Chinensis 18 parts, Herba tiarellae polyphyllae 14 parts, Radix bidentis tripartitae 16 parts, Lathyrus palustris L. Var.linearifolius Ser. 20 parts, Herba oxytropis glabrae 18 parts.
The described Chinese medicine composition being used for the treatment of cervicitis, dosage form is pharmaceutically acceptable granule, tablet, capsule.
The described Chinese medicine composition being used for the treatment of cervicitis, preparation process is: get above-mentioned Chinese medicine, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add adjuvant and make granule, tablet, capsule.
The described application of Chinese medicine composition in preparation treatment cervicitis medicine being used for the treatment of cervicitis.
Folium catalpae bungei is Bignoniaceae plant Chinese catalpa moral blade.Dryopteris lacera (Thunb.) O. Ktze. is rhizome and the leaf of Dryopteridaceae plant narrow top shield-fern.Radix et Rhizoma Thalictri Faberi is the root and rhizome of ranunculaceae plant great Ye Thalictrum aquilegifolium L. var. sibiricum Regel.Herba Elsholtziae Ciliatae is the herb of labiate Herba Moslae.Herba Hydrocotylis Chinensis is the herb of samphire Herba Hydrocotylis Chinensis.Herba tiarellae polyphyllae is the herb of saxifragaceae plant Herba tiarellae polyphyllae.Radix bidentis tripartitae is the root of feverfew Herba Bidentis Tripartitae.Lathyrus palustris L. Var.linearifolius Ser. is the herb of leguminous plant spire Herba Lathyri pratensis.Herba oxytropis glabrae is the herb of leguminous plant glabrous crazyweed.
Beneficial effect: invigorating the spleen and replenishing QI of the present invention, heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, full side's treatment cervicitis successful.
Detailed description of the invention
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example, all technology realized based on foregoing of the present invention all belong to scope of the present invention.
1, the preparation of granule embodiment: get Folium catalpae bungei 20g, leaf Radix et Rhizoma Thalictri 16g, Herba Elsholtziae Ciliatae 20g, Herba Hydrocotylis Chinensis 18g, Herba tiarellae polyphyllae 14g, Radix bidentis tripartitae 16g, Lathyrus palustris L. Var.linearifolius Ser. 20g, Herba oxytropis glabrae 18g, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add starch 50g, granulate, make granule.
2, the preparation of Tablets Example: get Folium catalpae bungei 20g, leaf Radix et Rhizoma Thalictri 16g, Herba Elsholtziae Ciliatae 20g, Herba Hydrocotylis Chinensis 18g, Herba tiarellae polyphyllae 14g, Radix bidentis tripartitae 16g, Lathyrus palustris L. Var.linearifolius Ser. 20g, Herba oxytropis glabrae 18g, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add dextrin 50g, granulate, tabletting, make tablet.
3, the preparation of capsule embodiment: get Folium catalpae bungei 20g, leaf Radix et Rhizoma Thalictri 16g, Herba Elsholtziae Ciliatae 20g, Herba Hydrocotylis Chinensis 18g, Herba tiarellae polyphyllae 14g, Radix bidentis tripartitae 16g, Lathyrus palustris L. Var.linearifolius Ser. 20g, Herba oxytropis glabrae 18g, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add starch 50g, granulate, fill, make capsule.
4, traditional Chinese medicine composition for treating cervicitis of the present invention clinical research
Case selection: as the medicine for the treatment of cervicitis, select the routine clinical observation of virus in patients with cervicitis 50 of making a definite diagnosis, patient is divided into treatment group and matched group two groups at random, treatment group 25 example, 26 ~ 43 years old age, 35.8 years old mean age, the course of disease 1 ~ 2 year; Matched group women 25 example, 21 ~ 56 years old age, 37.8 years old mean age, the course of disease 1 ~ 2 year; The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
Diagnostic criteria: (one) clinical manifestation 1. vaginal secretions increases, many in mucus purulence, or be mixed with blood.2. pruritus vulvae and burning sensation, caused by how per vaginam secretions stimulates.(2) auxiliary examination 1. secretions white blood cell detection: Gram's staining made by cervical canal purulent secretion smear, neutrophilic granulocyte >30/HPF; Or vaginal secretions humidity strip checks, leukocyte >10/HPF, and get rid of colpitis.2. cervix uteri is drawn materials pathogen detection: should do gonococcus and chlamydial detection, and with or without the detection of bacterial vaginosis and trichomonal vaginitis.(1) detection method that gonococcus is conventional: 1. secretions smear Gram's staining: search in neutrophilic granulocyte with or without gram-negative diplococcus; 2. gonococcus is cultivated: for diagnosing the goldstandard of gonorrhea; 3. detection of nucleic acids: comprise nucleic acid hybridization and nucleic acid amplification.(2) detection method that chlamydia trachomatis is conventional: 1. cell culture: be diagnosis meeting standard, because its method is complicated, clinical less application; 2. elisa: detecting Chlamydia antigen, is clinical common method; 3. detection of nucleic acids: comprise nucleic acid hybridization and nucleic acid amplification, especially the latter detects responsive, the special method of chlamydia infection.
Medicament selection: the preparation method that treatment group takes above-mentioned granule embodiment prepares medicine of the present invention, oral, every day 3 times, each 1 time sooner or later, each 10g, after meal warm water delivery service; Within 15 days, be 1 course for the treatment of, 2 ~ 4 courses for the treatment of can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.Matched group takes moldin sheet, oral, every day 2 times, each 1 time sooner or later, each 2; Within 10 days, be 1 course for the treatment of, take 3 ~ 5 courses for the treatment of continuously, the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Efficacy determination: (1) cures: with transference cures such as the bloods streak in leucorrhoea grow in quantity, purulence and leucorrhea, physical distress malaise symptoms disappears.(2) effective: to alleviate to some extent with symptoms such as the bloods streak in leucorrhoea grow in quantity, purulence and leucorrhea, physical distress malaise symptoms alleviates.(3) invalid: clinical symptoms is without obvious change.
Therapeutic effect: in table 1.
Table 1 liang group comparitive study
| Group | n | Cure | Effectively | Invalid | Total effective rate (%) |
| Treatment group | 25 | 14 | 9 | 2 | 92 |
| Blank group | 25 | 0 | 1 | 24 | 4 |
Visible the present invention has good therapeutic effect to cervicitis, and toxic and side effects does not occur treatments period.
Claims (2)
1. one kind is used for the treatment of the Chinese medicine composition of cervicitis, it is characterized in that, the active component contained by it is extracted by following raw materials in part by weight medicine and is prepared from: Folium catalpae bungei 20 parts, leaf Radix et Rhizoma Thalictri 16 parts, Herba Elsholtziae Ciliatae 20 parts, Herba Hydrocotylis Chinensis 18 parts, Herba tiarellae polyphyllae 14 parts, Radix bidentis tripartitae 16 parts, Lathyrus palustris L. Var.linearifolius Ser. 20 parts, Herba oxytropis glabrae 18 parts.
2. be used for the treatment of the application of Chinese medicine composition in treatment cervicitis medicine of cervicitis according to claim 1.
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| CN201510276661.1A CN104857096A (en) | 2015-05-26 | 2015-05-26 | Traditional Chinese medicine composition for treating cervicitis |
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| CN201510276661.1A CN104857096A (en) | 2015-05-26 | 2015-05-26 | Traditional Chinese medicine composition for treating cervicitis |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106038913A (en) * | 2016-06-27 | 2016-10-26 | 上海中医药大学附属岳阳中西医结合医院 | Traditional Chinese medicine composition for treating gynecological cervicitis and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1631414A (en) * | 2004-11-15 | 2005-06-29 | 长春今来药业（集团）有限公司 | Medicinal capsule for treating gynecological inflammation and its preparation process |
| CN103977149A (en) * | 2014-06-01 | 2014-08-13 | 徐静 | Traditional Chinese medicinal preparation for treating cervicitis and preparation method |
-
2015
- 2015-05-26 CN CN201510276661.1A patent/CN104857096A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1631414A (en) * | 2004-11-15 | 2005-06-29 | 长春今来药业（集团）有限公司 | Medicinal capsule for treating gynecological inflammation and its preparation process |
| CN103977149A (en) * | 2014-06-01 | 2014-08-13 | 徐静 | Traditional Chinese medicinal preparation for treating cervicitis and preparation method |
Non-Patent Citations (2)
| Title |
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| 谢靳等: "《妇产科病奇难顽症特效疗法》", 30 June 2004, 科学技术文献出版社 * |
| 黄六平等: "自拟宫炎宁散治疗慢性宫颈炎临床疗效观察", 《亚太传统医药》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106038913A (en) * | 2016-06-27 | 2016-10-26 | 上海中医药大学附属岳阳中西医结合医院 | Traditional Chinese medicine composition for treating gynecological cervicitis and application thereof |
| CN106038913B (en) * | 2016-06-27 | 2019-05-07 | 上海中医药大学附属岳阳中西医结合医院 | A kind of Chinese medicine composition that treating Gynecological cervical inflammation and its application |
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