CN101732425B - Externally-applied medicine composite for psoriasis - Google Patents

Externally-applied medicine composite for psoriasis Download PDF

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Publication number
CN101732425B
CN101732425B CN2010100229474A CN201010022947A CN101732425B CN 101732425 B CN101732425 B CN 101732425B CN 2010100229474 A CN2010100229474 A CN 2010100229474A CN 201010022947 A CN201010022947 A CN 201010022947A CN 101732425 B CN101732425 B CN 101732425B
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parts
radix
psoriasis
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externally applied
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CN101732425A (en
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高欣
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Sanlin Gaoxin Dermatology Clinic Shanghai Pudong Xinqu
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Sanlin Gaoxin Dermatology Clinic Shanghai Pudong Xinqu
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Abstract

The invention relates to an externally-applied medicine composite for psoriasis. The components of the composite comprise the alcohol extracts of the following raw materials in parts by weight: 10-20 parts of orpiment, 5-10 parts of indigo, 10-20 parts of rhubarb, 5-10 parts of redroot gromwell root, 10-15 parts of licorice, 10-20 parts of radix salviae miltiorrhizae, 10-20 parts of asarum, 10-20 parts of nutgall and 5-10 parts of cinnamon. The externally-applied medicine composite for the psoriasis, which is provided by the invention, adopts a prescription of treating both the principal and secondary aspects of diseases for lessening the virulence of any pathogenic organism, removing heat from the blood, reducing fever, moistening dryness, drawing out poison and killing bacteria, can cure refractory psoriasis and is not easy to cause relapse after curing.

Description

A kind of externally applied agent for treating psoriasis compositions
Technical field
The present invention relates to a kind of herbal composite, particularly, relate to the psoriasic externally-applied medicine composite of a kind of treatment intractable.
Background technology
The doctor trained in Western medicine theory of psoriasis (also claiming psoriasis) thinks by heredity virus, due to the bacterial infection, direct stimulation, hypoimmunity.Theory of Chinese medical science is thought wind, wet, hot invasion skin histology reduces Abwehrkraft des Koepers, wind syndrome due to blood-deficiency, and noxious dampness is given birth to heat, due to the skin mistake is supported.More accurate fixed theory is still indeterminate so far.Psoriasis is mainly in incidence, extremity, and be symmetrical distribution; Clinical manifestation is for being syringe needle shape or grain of rice shape pimple at first, then increases gradually, and epidermis thickens, and is dry and take off white scales in a large number, and skin lesion place pruritus unbearably.The medical circle common method of treatment is to adopt dexamethasone at present, prednisone, and the treatment of hormonal medicaments such as De Baosong, effect is undesirable, and side effect is big, and drug dependence is strong, easily recurrence.Also having a lot of Chinese herbal and crude drugs preparationses is Main Ingredients and Appearance with Cortex Moutan, Radix Rubiae, Flos Lonicerae, Cortex Dictamni, Spina Gleditsiae, the Fructus Kochiae, Radix Paeoniae Rubra, Poria etc., and pharmacology lacks the effect of hard masses softening and resolving, detoxicating and killing parasites based on detoxifcation, dandruff-removing itching-relieve.In addition, also have some medicine for external use or ointment, though external can be played sterilizing and itch-relieving, lubricated skin, the dry and cracked effect of control, curative effect does not very significantly reach the purpose of radical cure yet.
Summary of the invention
The objective of the invention is to propose a kind ofly can cure the intractable psoriasis, and cure the Chinese herbal medicine medicine for external use that the back is difficult for recurrence, be characterized in instant effect, short treating period, the cure rate height is difficult for recurrence.
For achieving the above object, the invention provides a kind of externally applied agent for treating psoriasis compositions, the component of said composition is the alcoholic extract of following raw materials in part by weight:
Figure GSB00000474381600011
Figure GSB00000474381600021
Further, the component of externally applied agent for treating psoriasis compositions provided by the invention is the alcoholic extract of following raw materials in part by weight:
Figure GSB00000474381600022
Further, the weight portion proportioning of the raw material of the optimum formula of externally applied agent for treating psoriasis compositions of the present invention is:
Figure GSB00000474381600023
Externally applied agent for treating psoriasis compositions of the present invention is to adopt the ethanol of 75% concentration that described raw material is flooded to extract to form.
Medicine for external use of the present invention is according to the Chinese medical discrimination theory, and cold because the human body wind-engaging, wet, heat is invaded skin, causes energy and blood of human body not smooth, qi depression to blood stasis, and burning hot turbid damp, failure of skin and muscle to be nourished, intense heat bringing about wind syndrome, wind is contained dryness-transformation, and vim and vigour viscous move not freely, with the passing of time is void.Must adopt the detoxifcation removing heat from blood so cure primary disease, clearing heat and moistening dryness, the side of germ-resistant treating both the principal and secondary aspects of a disease that draws out pus by applying a plaster to the affected part just can reach the radical cure effect for the treatment of both the principal and secondary aspects of a disease.Each medicine pharmacology side of this medicine composition separate and monarch as follows:
Monarch drug:
Realgar: the detoxifcation parasite killing, damp eliminating is dry;
Galla Chinensis: removing dampness is held back skin ulcer, the pathogenic fire reducing of astringing the lung.
Ministerial drug:
Herba Asari: dispel the wind, cold expelling, row water is had one's ideas straightened out;
Radix Glycyrrhizae: heat-clearing and toxic substances removing, coordinating the actions of various ingredients in a prescription;
Radix Salviae Miltiorrhizae: blood circulation promoting and blood stasis dispelling, opening becomes silted up leads to.
Adjuvant drug:
Cortex Cinnamomi: disinfection, relieving the exterior syndrome by diaphoresis, promoting blood circulation by removing blood stasis;
Radix Et Rhizoma Rhei: removing pathogenic heat from blood and toxic substance from the body, stimulate the menstrual flow by becoming silted up.
Messenger drug:
Radix Arnebiae (Radix Lithospermi): removing heat from blood and promoting blood circulation, detoxifcation rash;
Indigo Naturalis: heat-clearing and toxic substances removing, removing heat from blood dehumidifying.
The present invention adopts the detoxifcation removing heat from blood according to the Chinese medical discrimination theory, clearing heat and moistening dryness, and the side of germ-resistant treating both the principal and secondary aspects of a disease that draws out pus by applying a plaster to the affected part, in 3 years, the inventor uses the treatment of this medicine to 188 routine patients and observes in the past, wherein male 142 examples, women 42 examples, the age is 15 years old to 65 years old.After the medication, 176 examples are cured, and cure rate reaches 93.6%; Effective 188 examples of medication, effective percentage is 100%.
The specific embodiment
Below in conjunction with embodiment technical scheme of the present invention is further described:
Embodiment 1
Raw material with following parts by weight:
Figure GSB00000474381600031
Pulverize with pulverizer, cross 120 mesh sieves after, put into the container mix homogeneously, in container, pour 3000 milliliters of the ethanol of 75% concentration then into, stir; With seal of vessel, place the storage of shady and cool place and got final product in 10 days then.During use, its supernatant is poured in the bottle, use to get final product.
Embodiment 2
Raw material with following parts by weight:
Figure GSB00000474381600032
Pulverize with pulverizer, cross 120 mesh sieves after, put into the container mix homogeneously, in container, pour 3000 milliliters of the ethanol of 75% concentration then into, stir; With seal of vessel, place the storage of shady and cool place and got final product in 10 days then.During use, its supernatant is poured in the bottle, use to get final product.
Embodiment 3
Raw material with following parts by weight:
Figure GSB00000474381600041
Pulverize with pulverizer, cross 120 mesh sieves after, put into the container mix homogeneously, in container, pour 3000 milliliters of the ethanol of 75% concentration then into, stir; With seal of vessel, place the storage of shady and cool place and got final product in 10 days then.During use, its supernatant is poured in the bottle, use to get final product.
Embodiment 4
Raw material with following parts by weight:
Figure GSB00000474381600042
Pulverize with pulverizer, cross 120 mesh sieves after, put into the container mix homogeneously, in container, pour 3000 milliliters of the ethanol of 75% concentration then into, stir; With seal of vessel, place the storage of shady and cool place and got final product in 10 days then.During use, its supernatant is poured in the bottle, use to get final product.
Embodiment 5
Raw material with following parts by weight:
Figure GSB00000474381600043
Pulverize with pulverizer, cross 120 mesh sieves after, put into the container mix homogeneously, in container, pour 3000 milliliters of the ethanol of 75% concentration then into, stir; With seal of vessel, place the storage of shady and cool place and got final product in 10 days then.During use, its supernatant is poured in the bottle, use to get final product.
The using method of externally applied agent for treating psoriasis of the present invention: get this medicine and embrocate in the skin lesion place, four times a day, early, middle and late and sleep before.Use the basic recovery process of each stage disease of this medicine:
1. use first week of this medicine back:
The thick bits attenuation of whole body psoriasis pathological changes place's epidermis, scurf reduces, and surface sclerosis skin limbers up, and skin pruritus obviously reduces.
2. use second week of this medicine back:
Skin lesion thickened section position, surface thinning of skin, the red rash color dodge, the surface does not have newborn squama, and skin lesion place skin is obviously soft.
3. use the 3rd week of this medicine back:
Former skin lesion peony erythra becomes pale red, surperficial chipless, and the skin gradual change of former desquamation place is smooth, and scratchiness disappears substantially.
4. after using around this medicine:
The skin lesion place becomes pale pink, the basic chipless in surface, and nothing is itched, and does not have newborn erythra.
5. use the 6th week of this medicine back:
Epidermis reverts to normal color substantially, and chipless is smooth, and the calm speckle of a small amount of protochrome is arranged, and nothing is itched.The pigmentation spots at former psoriasis place needs a period of time to recover naturally.
The inventor uses the treatment of this medicine to 188 routine patients and observes, wherein male 142 examples, and women 42 examples, the age is 15 years old to 65 years old.After the medication, 176 examples are cured, and cure rate reaches 93.6%; Effective 188 examples of medication, effective percentage is 100%.
Embodiment 6
The patient's name: Cai XX, the man, 24 years old, people from Shanghai City, the civil servant suffered from psoriasis 5 years.The red macule of burst right lower extremity in 2004, the multiple thick crust in surface is scratched the back and is formed white squama, a large amount of white decortications, the hyperemia of basilar part skin point-like is diagnosed as psoriasis (psoriasis).Its mother accompanies him to remove many famous large hospitals over 5 years, and Western medicine hormone therapy 3 years is invalid, the oral traditional Chinese medical science decoction treatment in back 2 years, the state of an illness is more and more heavier, and diffusion from the crown to instep, general of whole body large tracts of land is the map shape and distributes.The patient is depressed, loses treatment confidence, can't operate as normal.After coming the court to use Drug therapy of the present invention, face and whole body dermatosis take a turn for the better rapidly, and after 4 weeks of medication, General Symptoms disappears, and follows up a case by regular visits to so far and does not recur.
Embodiment 7
The patient's name: the XX of the Qin, the man, 29 years old, people from Shanghai City, the IT manager suffered from psoriasis 6 years.Happened suddenly in 2003 in the red macule of women's head-ornaments portion, violent pruritus is accompanied in a large amount of decortications; Be diagnosed as psoriasis in specialist hospital, after the treatment of Western medicine hormones, the state of an illness does not take a turn for the better, and spreads to whole body, and extremity are in a bad way, to such an extent as to can't wear short sweater and pants summer, have a strong impact on work and life.After coming the court to use Drug therapy of the present invention, facial skin is sick to take a turn for the better rapidly, and after 5 weeks of medication, General Symptoms disappears, and follows up a case by regular visits to so far and does not recur.
Embodiment 8
The patient's name: yellow XX, the man, 40 years old, people from Jiangsu, the workman suffered from psoriasis 15 years.Before 15 years, after suffering from cold because of drenching with rain, the whole body red macule of dashing forward, the multiple thick crust in surface is scratched the back and is formed white squama, a large amount of white decortications, the hyperemia of basilar part skin point-like is psoriasis (psoriasis) at a local hospital diagnosis.The patient went to a doctor in many famous hospitals always in 15 years, adopted western medicines in treatment, and all invalid, the state of an illness is more and more heavier, to facial, reached general of extremity large tracts of land from the crown, and face is in a bad way, and almost disfeatures.Patient's emotion is extremely low, loses treatment confidence, can't operate as normal, also bring immense pressure economically.After coming the court to use Drug therapy of the present invention, face and whole body dermatosis take a turn for the better rapidly, and after 6 weeks of medication, General Symptoms disappears, and follows up a case by regular visits to so far and does not recur.
The present invention is according to the Chinese medical discrimination theory, adopt the detoxifcation removing heat from blood, clearing heat and moistening dryness, the side of germ-resistant treating both the principal and secondary aspects of a disease that draws out pus by applying a plaster to the affected part is a monarch drug with Realgar and Galla Chinensis, and Herba Asari, Radix Glycyrrhizae, Radix Salviae Miltiorrhizae are ministerial drug, Cortex Cinnamomi, Radix Et Rhizoma Rhei are adjuvant drug, Radix Arnebiae (Radix Lithospermi), Indigo Naturalis are the pharmaceutical composition of messenger drug, and this pharmaceutical composition can be cured the intractable psoriasis, and cure the difficult recurrence in back.
Although content of the present invention has been done detailed introduction by above preferred embodiment, will be appreciated that above-mentioned description should not be considered to limitation of the present invention.After those skilled in the art have read foregoing, for multiple modification of the present invention with to substitute all will be conspicuous.Therefore, protection scope of the present invention should be limited to the appended claims.

Claims (4)

1. an externally applied agent for treating psoriasis compositions is characterized in that, the component of said composition is the alcoholic extract of following raw materials in part by weight:
5~10 parts of 10~20 parts of Indigo Naturaliss of Realgar
5~10 parts of 10~20 portions of Radix Arnebiae (Radix Lithospermi)s of Radix Et Rhizoma Rhei
10~20 parts of 10~15 parts of Radix Salviae Miltiorrhizaes of Radix Glycyrrhizae
10~20 parts of 10~20 parts of Galla Chinensiss of Herba Asari
5~10 parts of Cortex Cinnamomis.
2. externally applied agent for treating psoriasis compositions as claimed in claim 1 is characterized in that, the weight portion proportioning of described raw material is:
7~8 parts of 14~18 parts of Indigo Naturaliss of Realgar
6~9 parts of 12~16 portions of Radix Arnebiae (Radix Lithospermi)s of Radix Et Rhizoma Rhei
12~16 parts of 12~14 parts of Radix Salviae Miltiorrhizaes of Radix Glycyrrhizae
12~16 parts of 14~18 parts of Galla Chinensiss of Herba Asari
6~9 parts of Cortex Cinnamomis.
3. externally applied agent for treating psoriasis compositions as claimed in claim 2 is characterized in that, the weight portion proportioning of described raw material is:
7 parts of 14 parts of Indigo Naturaliss of Realgar
6 parts of 15 portions of Radix Arnebiae (Radix Lithospermi)s of Radix Et Rhizoma Rhei
14 parts of 14 parts of Radix Salviae Miltiorrhizaes of Radix Glycyrrhizae
16 parts of 14 parts of Galla Chinensiss of Herba Asari
6 parts of Cortex Cinnamomis.
4. as any described externally applied agent for treating psoriasis compositions of claim 1~3, it is characterized in that described alcohol concentration is 75%.
CN2010100229474A 2010-01-19 2010-01-19 Externally-applied medicine composite for psoriasis Expired - Fee Related CN101732425B (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104958358A (en) * 2015-07-24 2015-10-07 王玉生 Traditional Chinese medicinal composition for treating psoriasis and preparation method thereof
CN107320609A (en) * 2017-07-17 2017-11-07 王永君 One kind decomposes the psoriasic skin imbibition reduction cream of recurrent and preparation method

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1319422A (en) * 2001-01-11 2001-10-31 厉建仁 Medicine for treating psoriasis
CN101468070A (en) * 2007-12-27 2009-07-01 天津天阜康生物技术发展有限公司 Medicinal composition for treating acne and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1319422A (en) * 2001-01-11 2001-10-31 厉建仁 Medicine for treating psoriasis
CN101468070A (en) * 2007-12-27 2009-07-01 天津天阜康生物技术发展有限公司 Medicinal composition for treating acne and preparation method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
宋兆友等."皮肤病中药内用制剂研究进展".《皮肤病与性病》.2007,第29卷(第3期),27-29.
李萍."银屑病中医治疗近况".《光明中医》.2002,第17卷(第98期),46-49.

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