CN103965302B - 一种重组超抗原seb突变体,其制备方法及应用 - Google Patents
一种重组超抗原seb突变体,其制备方法及应用 Download PDFInfo
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- CN103965302B CN103965302B CN201310031999.1A CN201310031999A CN103965302B CN 103965302 B CN103965302 B CN 103965302B CN 201310031999 A CN201310031999 A CN 201310031999A CN 103965302 B CN103965302 B CN 103965302B
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
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- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Description
Claims (7)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201310031999.1A CN103965302B (zh) | 2013-01-29 | 2013-01-29 | 一种重组超抗原seb突变体,其制备方法及应用 |
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CN201310031999.1A CN103965302B (zh) | 2013-01-29 | 2013-01-29 | 一种重组超抗原seb突变体,其制备方法及应用 |
Publications (2)
Publication Number | Publication Date |
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CN103965302A CN103965302A (zh) | 2014-08-06 |
CN103965302B true CN103965302B (zh) | 2019-05-28 |
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CN201310031999.1A Active CN103965302B (zh) | 2013-01-29 | 2013-01-29 | 一种重组超抗原seb突变体,其制备方法及应用 |
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Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN107312781B (zh) * | 2017-08-31 | 2020-04-21 | 曾庆明 | 重组金黄色葡萄球菌b型肠毒素蛋白及其制备方法与应用 |
KR20220132641A (ko) * | 2020-12-18 | 2022-09-30 | 비오메디찌니쉐 포르슝 운트 바이오-프로듀테 아게 | 보호성 스타필로코커스 외독소 백신 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5601830A (en) * | 1995-03-31 | 1997-02-11 | Wisconsin Alumni Research Foundation | Staphylococcus aureus enterotoxin H and methods of use |
CN1332804A (zh) * | 1998-06-24 | 2002-01-23 | 病毒科学公司 | 监控核苷类逆转录酶抑制剂抗逆转录病毒治疗和在治疗hiv/aids中指导治疗决定的途径与方法 |
CN1522156A (zh) * | 2001-06-28 | 2004-08-18 | ��Ծ���\������˾ | 用于人类治疗的新的工程化超抗原 |
EP1980254A1 (en) * | 2007-04-13 | 2008-10-15 | Rijksuniversiteit te Groningen | Means and methods for counteracting protein aggregation |
CN102516392A (zh) * | 2011-11-25 | 2012-06-27 | 孙嘉琳 | 一种癌靶向超抗原融合蛋白及制备方法及用途 |
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2013
- 2013-01-29 CN CN201310031999.1A patent/CN103965302B/zh active Active
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5601830A (en) * | 1995-03-31 | 1997-02-11 | Wisconsin Alumni Research Foundation | Staphylococcus aureus enterotoxin H and methods of use |
CN1332804A (zh) * | 1998-06-24 | 2002-01-23 | 病毒科学公司 | 监控核苷类逆转录酶抑制剂抗逆转录病毒治疗和在治疗hiv/aids中指导治疗决定的途径与方法 |
CN1522156A (zh) * | 2001-06-28 | 2004-08-18 | ��Ծ���\������˾ | 用于人类治疗的新的工程化超抗原 |
EP1980254A1 (en) * | 2007-04-13 | 2008-10-15 | Rijksuniversiteit te Groningen | Means and methods for counteracting protein aggregation |
CN102516392A (zh) * | 2011-11-25 | 2012-06-27 | 孙嘉琳 | 一种癌靶向超抗原融合蛋白及制备方法及用途 |
Non-Patent Citations (2)
Title |
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A DNA Spiegelmer to staphylococcal enterotoxin B;Purschke WG 等;《Nucleic Acids Res》;20030615;第31卷(第12期);第3027-3032页 * |
葡萄球菌肠毒素B突变体的构建及其抗肿瘤活性分析;郑欣 等;《生物技术通讯》;20121130;第23卷(第6期);第772-776页 * |
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Address after: 100071 Beijing Fengtai District, East Street, No. 20, Five Rooms and One Room Applicant after: Institute of Microbial Epidemiology, Military Medical Research Institute, Academy of Military Sciences Address before: 100071 No. 20 East Main Street, Beijing, Fengtai District Applicant before: Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, PR China |
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Inventor after: Zheng Yuling Inventor after: Jiang Hua Inventor after: Jiang Yongqiang Inventor after: Gu Liwei Inventor after: Zheng Xin Inventor after: Wang Jun Inventor after: Wang Yanzi Inventor before: Jiang Yongqiang Inventor before: Jiang Hua Inventor before: Zheng Yuling Inventor before: Gu Liwei Inventor before: Zheng Xin Inventor before: Wang Jun Inventor before: Wang Yanzi |
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