CN103957906A - 使用右美托咪定治疗儿科患者的方法 - Google Patents

使用右美托咪定治疗儿科患者的方法 Download PDF

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Publication number
CN103957906A
CN103957906A CN201280058634.1A CN201280058634A CN103957906A CN 103957906 A CN103957906 A CN 103957906A CN 201280058634 A CN201280058634 A CN 201280058634A CN 103957906 A CN103957906 A CN 103957906A
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China
Prior art keywords
dexmedetomidine
dose
infusion
subjects
group
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Pending
Application number
CN201280058634.1A
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English (en)
Chinese (zh)
Inventor
M·加西亚德罗查
W·威斯曼德勒
D·J·斯托克
E·库
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Hospira Inc
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Hospira Inc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47226666&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN103957906(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hospira Inc filed Critical Hospira Inc
Priority to CN201811538616.9A priority Critical patent/CN109700806A/zh
Publication of CN103957906A publication Critical patent/CN103957906A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN201280058634.1A 2011-10-14 2012-09-27 使用右美托咪定治疗儿科患者的方法 Pending CN103957906A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201811538616.9A CN109700806A (zh) 2011-10-14 2012-09-27 使用右美托咪定治疗儿科患者的方法

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201161547626P 2011-10-14 2011-10-14
US61/547.626 2011-10-14
US13/343,693 US20130096170A1 (en) 2011-10-14 2012-01-04 Methods of treating pediatric patients using dexmedetomidine
US13/343,693 2012-01-04
US13/471,403 2012-05-14
US13/471,403 US8324260B1 (en) 2011-10-14 2012-05-14 Methods of treating pediatric patients using dexmedetomidine
PCT/US2012/057652 WO2013055528A1 (en) 2011-10-14 2012-09-27 Methods of treating pediatric patients using dexmedetomidine

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201811538616.9A Division CN109700806A (zh) 2011-10-14 2012-09-27 使用右美托咪定治疗儿科患者的方法

Publications (1)

Publication Number Publication Date
CN103957906A true CN103957906A (zh) 2014-07-30

Family

ID=47226666

Family Applications (2)

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CN201280058634.1A Pending CN103957906A (zh) 2011-10-14 2012-09-27 使用右美托咪定治疗儿科患者的方法
CN201811538616.9A Pending CN109700806A (zh) 2011-10-14 2012-09-27 使用右美托咪定治疗儿科患者的方法

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CN201811538616.9A Pending CN109700806A (zh) 2011-10-14 2012-09-27 使用右美托咪定治疗儿科患者的方法

Country Status (23)

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US (8) US20130096170A1 (enExample)
EP (2) EP3446691A1 (enExample)
JP (5) JP6270727B2 (enExample)
KR (3) KR20200019791A (enExample)
CN (2) CN103957906A (enExample)
AU (3) AU2012321246C1 (enExample)
BR (1) BR112014008983A2 (enExample)
CA (2) CA2851780C (enExample)
CY (1) CY1121041T1 (enExample)
DK (1) DK2766014T3 (enExample)
ES (1) ES2685814T3 (enExample)
HK (1) HK1200333A1 (enExample)
HR (1) HRP20181378T1 (enExample)
HU (1) HUE039671T2 (enExample)
IL (2) IL232070A0 (enExample)
IN (1) IN2014KN00996A (enExample)
LT (1) LT2766014T (enExample)
MX (1) MX362626B (enExample)
PL (1) PL2766014T3 (enExample)
PT (1) PT2766014T (enExample)
RS (1) RS57660B1 (enExample)
SI (1) SI2766014T1 (enExample)
WO (1) WO2013055528A1 (enExample)

Cited By (4)

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CN105287519A (zh) * 2015-03-06 2016-02-03 北京大学第一医院 一种预防术后谵妄的药物组合物
CN106539778A (zh) * 2016-12-08 2017-03-29 武汉大学 一种小儿麻醉术前含服口腔泡腾片及其制备方法
CN108042533A (zh) * 2017-12-25 2018-05-18 陈锦辉 右美托米定在制备用于预防和/或抑制创伤性脑损伤后的神经元死亡的药物组合物中的用途
CN109793709A (zh) * 2019-02-22 2019-05-24 青岛农业大学 一种斑海豹用复方注射剂及其制备方法

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US8242158B1 (en) * 2012-01-04 2012-08-14 Hospira, Inc. Dexmedetomidine premix formulation
ES2855103T3 (es) * 2013-10-07 2021-09-23 Teikoku Pharma Usa Inc Dispositivo de suministro transdérmico para el control del dolor que comprende composiciones transdérmicas de dexmedetomidina
KR20180095732A (ko) 2013-10-07 2018-08-27 테이코쿠 팔마 유에스에이, 인코포레이티드 비진정량의 덱스메데토미딘의 경피 전달을 위한 방법 및 조성물
CA2924231C (en) 2013-10-07 2018-04-03 Teikoku Pharma Usa, Inc. Dexmedetomidine transdermal delivery devices and methods for using the same
CN106456561B (zh) 2013-10-07 2020-02-28 帝国制药美国公司 使用右旋美托咪啶经皮组合物治疗注意力缺陷多动症、焦虑症和失眠症的方法和组合物
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US9717796B1 (en) * 2016-04-20 2017-08-01 Slypharma, Llc Heat sterilizeable, premixed, ready to use dexmedetomidine solution packaged in a flexible plastic container
CA3038354C (en) * 2016-10-31 2021-08-17 Teikoku Pharma Usa, Inc. Methods of managing pain using dexmedetomidine transdermal delivery devices
EP3562486B1 (en) 2016-12-31 2024-03-13 Bioxcel Therapeutics, Inc. Use of sublingual dexmedetomidine for the treatment of agitation
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US20210267944A1 (en) * 2018-06-27 2021-09-02 Bioxcel Therapeutics, Inc. Methods for treating agitation using dexmedetomidine hydrochloride
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US20220054455A1 (en) * 2018-09-13 2022-02-24 Taiwan Liposome Co., Ltd. Sustained-release pharmaceutical compositions comprising of a sedative drug and uses thereof
US20220051802A1 (en) * 2018-12-13 2022-02-17 Dignity Health System and method for detection and monitoring of over sedation to prevent harm to patients
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US11000488B2 (en) * 2019-03-22 2021-05-11 Syntrix Biosystems Inc. Treating pain using desmetramadol
AU2020316013A1 (en) * 2019-07-19 2022-02-17 Arx, Llc Non-sedating dexmedetomidine treatment regimens
US20230165520A1 (en) * 2020-04-17 2023-06-01 Bioventures, Llc Methods and systems for predicting the effect of inhaled and infused anesthetics
KR102815903B1 (ko) 2021-12-21 2025-05-30 충남대학교산학협력단 감염 환자에서 반코마이신 최적 용량을 결정하는 방법
EP4386768A1 (en) * 2022-12-13 2024-06-19 Koninklijke Philips N.V. Active sleep apnea case finding and scheduling system and method of operation thereof
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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105287519A (zh) * 2015-03-06 2016-02-03 北京大学第一医院 一种预防术后谵妄的药物组合物
CN106539778A (zh) * 2016-12-08 2017-03-29 武汉大学 一种小儿麻醉术前含服口腔泡腾片及其制备方法
CN108042533A (zh) * 2017-12-25 2018-05-18 陈锦辉 右美托米定在制备用于预防和/或抑制创伤性脑损伤后的神经元死亡的药物组合物中的用途
WO2019129007A1 (zh) * 2017-12-25 2019-07-04 陈锦辉 右美托米定在制备用于预防和/或抑制创伤性脑损伤后的神经元死亡的药物组合物中的用途
CN108042533B (zh) * 2017-12-25 2020-11-13 苏州格兰科医药科技有限公司 右美托米定在制备用于预防和/或抑制创伤性脑损伤后的神经元死亡的药物组合物中的用途
CN109793709A (zh) * 2019-02-22 2019-05-24 青岛农业大学 一种斑海豹用复方注射剂及其制备方法

Also Published As

Publication number Publication date
AU2017206211B2 (en) 2019-02-28
JP2023179764A (ja) 2023-12-19
US8324260B1 (en) 2012-12-04
EP3446691A1 (en) 2019-02-27
US20190269657A1 (en) 2019-09-05
JP2014528474A (ja) 2014-10-27
CA2978258A1 (en) 2013-04-18
JP6270727B2 (ja) 2018-01-31
JP2020073529A (ja) 2020-05-14
ES2685814T3 (es) 2018-10-11
SI2766014T1 (sl) 2018-11-30
US20130096171A1 (en) 2013-04-18
US8507542B2 (en) 2013-08-13
IN2014KN00996A (enExample) 2015-09-04
US9314449B2 (en) 2016-04-19
CY1121041T1 (el) 2019-12-11
PL2766014T3 (pl) 2019-02-28
AU2019203564A1 (en) 2019-06-13
KR20200019791A (ko) 2020-02-24
KR20190029775A (ko) 2019-03-20
LT2766014T (lt) 2018-08-27
US20210137891A1 (en) 2021-05-13
US20130096172A1 (en) 2013-04-18
US20130096170A1 (en) 2013-04-18
EP2766014B1 (en) 2018-07-18
US20140005243A1 (en) 2014-01-02
DK2766014T3 (en) 2018-09-24
AU2012321246A1 (en) 2014-05-01
CA2851780C (en) 2017-11-28
BR112014008983A2 (pt) 2017-05-02
EP2766014A4 (en) 2015-06-24
CA2851780A1 (en) 2013-04-18
KR20140094539A (ko) 2014-07-30
IL249991A0 (en) 2017-03-30
AU2017206211A1 (en) 2017-08-03
MX362626B (es) 2019-01-28
WO2013055528A1 (en) 2013-04-18
AU2012321246B2 (en) 2017-05-04
HK1200333A1 (en) 2015-08-07
AU2012321246C1 (en) 2017-11-02
US20160067220A1 (en) 2016-03-10
RS57660B1 (sr) 2018-11-30
EP2766014A1 (en) 2014-08-20
JP2022008828A (ja) 2022-01-14
CN109700806A (zh) 2019-05-03
HUE039671T2 (hu) 2019-01-28
MX2014004548A (es) 2015-02-12
PT2766014T (pt) 2018-10-11
JP6640164B2 (ja) 2020-02-05
IL232070A0 (en) 2014-05-28
HRP20181378T1 (hr) 2018-10-19
JP2018027971A (ja) 2018-02-22

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