IL232070A0 - Methods of treating pediatric patients using dexmedetomidine - Google Patents
Methods of treating pediatric patients using dexmedetomidineInfo
- Publication number
- IL232070A0 IL232070A0 IL232070A IL23207014A IL232070A0 IL 232070 A0 IL232070 A0 IL 232070A0 IL 232070 A IL232070 A IL 232070A IL 23207014 A IL23207014 A IL 23207014A IL 232070 A0 IL232070 A0 IL 232070A0
- Authority
- IL
- Israel
- Prior art keywords
- dexmedetomidine
- methods
- sick children
- treating sick
- treating
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161547626P | 2011-10-14 | 2011-10-14 | |
| US13/343,693 US20130096170A1 (en) | 2011-10-14 | 2012-01-04 | Methods of treating pediatric patients using dexmedetomidine |
| US13/471,403 US8324260B1 (en) | 2011-10-14 | 2012-05-14 | Methods of treating pediatric patients using dexmedetomidine |
| PCT/US2012/057652 WO2013055528A1 (en) | 2011-10-14 | 2012-09-27 | Methods of treating pediatric patients using dexmedetomidine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL232070A0 true IL232070A0 (en) | 2014-05-28 |
Family
ID=47226666
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL232070A IL232070A0 (en) | 2011-10-14 | 2014-04-10 | Methods of treating pediatric patients using dexmedetomidine |
| IL249991A IL249991A0 (en) | 2011-10-14 | 2017-01-09 | Methods of treating pediatric patients using dexmedetomidine |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL249991A IL249991A0 (en) | 2011-10-14 | 2017-01-09 | Methods of treating pediatric patients using dexmedetomidine |
Country Status (23)
| Country | Link |
|---|---|
| US (8) | US20130096170A1 (enExample) |
| EP (2) | EP2766014B1 (enExample) |
| JP (5) | JP6270727B2 (enExample) |
| KR (3) | KR20140094539A (enExample) |
| CN (2) | CN103957906A (enExample) |
| AU (3) | AU2012321246C1 (enExample) |
| BR (1) | BR112014008983A2 (enExample) |
| CA (2) | CA2978258A1 (enExample) |
| CY (1) | CY1121041T1 (enExample) |
| DK (1) | DK2766014T3 (enExample) |
| ES (1) | ES2685814T3 (enExample) |
| HK (1) | HK1200333A1 (enExample) |
| HR (1) | HRP20181378T1 (enExample) |
| HU (1) | HUE039671T2 (enExample) |
| IL (2) | IL232070A0 (enExample) |
| IN (1) | IN2014KN00996A (enExample) |
| LT (1) | LT2766014T (enExample) |
| MX (1) | MX362626B (enExample) |
| PL (1) | PL2766014T3 (enExample) |
| PT (1) | PT2766014T (enExample) |
| RS (1) | RS57660B1 (enExample) |
| SI (1) | SI2766014T1 (enExample) |
| WO (1) | WO2013055528A1 (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130096170A1 (en) * | 2011-10-14 | 2013-04-18 | Hospira, Inc. | Methods of treating pediatric patients using dexmedetomidine |
| US8242158B1 (en) * | 2012-01-04 | 2012-08-14 | Hospira, Inc. | Dexmedetomidine premix formulation |
| RU2018105761A (ru) | 2013-10-07 | 2019-02-26 | ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК. | Устройства для трансдермальной доставки дексмедетомидина и способы их применения |
| RU2648449C2 (ru) * | 2013-10-07 | 2018-03-26 | ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК. | Способы и композиции для трансдермальной доставки неседативного количества дексмедетомидина |
| CN110604728A (zh) * | 2013-10-07 | 2019-12-24 | 帝国制药美国公司 | 用于管理疼痛的包含右旋美托咪啶经皮组合物的方法及组合物 |
| TWI709417B (zh) | 2013-10-07 | 2020-11-11 | 美商帝國製藥美國股份有限公司 | 使用右美托咪啶經皮組成物用於治療注意力不足過動症、焦慮及失眠的方法及組成物 |
| US11017330B2 (en) * | 2014-05-20 | 2021-05-25 | Elasticsearch B.V. | Method and system for analysing data |
| AU2015306075C1 (en) * | 2014-08-18 | 2021-08-26 | Electronic Pain Assessment Technologies (epat) Pty Ltd | A pain assessment method and system |
| CN104784174A (zh) * | 2015-03-06 | 2015-07-22 | 北京大学第一医院 | 右美托咪定的药物新用途 |
| US9717796B1 (en) * | 2016-04-20 | 2017-08-01 | Slypharma, Llc | Heat sterilizeable, premixed, ready to use dexmedetomidine solution packaged in a flexible plastic container |
| KR20210113439A (ko) * | 2016-10-31 | 2021-09-15 | 테이코쿠 팔마 유에스에이, 인코포레이티드 | 덱스메데토미딘 경피 전달 장치를 이용한 통증을 관리하는 방법 |
| CN106539778A (zh) * | 2016-12-08 | 2017-03-29 | 武汉大学 | 一种小儿麻醉术前含服口腔泡腾片及其制备方法 |
| SG10202107367SA (en) | 2016-12-31 | 2021-08-30 | Bioxcel Therapeutics Inc | Use of sublingual dexmedetomidine for the treatment of agitation |
| US11621969B2 (en) | 2017-04-26 | 2023-04-04 | Elasticsearch B.V. | Clustering and outlier detection in anomaly and causation detection for computing environments |
| US11783046B2 (en) | 2017-04-26 | 2023-10-10 | Elasticsearch B.V. | Anomaly and causation detection in computing environments |
| CN108042533B (zh) * | 2017-12-25 | 2020-11-13 | 苏州格兰科医药科技有限公司 | 右美托米定在制备用于预防和/或抑制创伤性脑损伤后的神经元死亡的药物组合物中的用途 |
| US20210267944A1 (en) * | 2018-06-27 | 2021-09-02 | Bioxcel Therapeutics, Inc. | Methods for treating agitation using dexmedetomidine hydrochloride |
| ES3004544T3 (en) | 2018-06-27 | 2025-03-12 | Bioxcel Therapeutics Inc | Film formulations containing dexmedetomidine and methods of producing them |
| KR102899320B1 (ko) | 2018-09-12 | 2025-12-12 | 호 이어 인스티튜트 | 인공 와우 수술에 따른 난청의 치료 방법 |
| WO2020056102A1 (en) * | 2018-09-13 | 2020-03-19 | Taiwan Liposome Co., Ltd. | Sustained-release pharmaceutical compositions comprising of a sedative drug and uses thereof |
| US20220051802A1 (en) * | 2018-12-13 | 2022-02-17 | Dignity Health | System and method for detection and monitoring of over sedation to prevent harm to patients |
| US10817669B2 (en) | 2019-01-14 | 2020-10-27 | International Business Machines Corporation | Automatic classification of adverse event text fragments |
| CN109793709A (zh) * | 2019-02-22 | 2019-05-24 | 青岛农业大学 | 一种斑海豹用复方注射剂及其制备方法 |
| US11000488B2 (en) * | 2019-03-22 | 2021-05-11 | Syntrix Biosystems Inc. | Treating pain using desmetramadol |
| US20240024288A1 (en) | 2019-07-19 | 2024-01-25 | Bioxcel Therapeutics, Inc. | Non-sedating dexmedetomidine treatment regimens |
| WO2021211507A1 (en) * | 2020-04-17 | 2021-10-21 | Bioventures, Llc | Methods and systems for predicting the effect of inhaled and infused anesthetics |
| KR102815903B1 (ko) | 2021-12-21 | 2025-05-30 | 충남대학교산학협력단 | 감염 환자에서 반코마이신 최적 용량을 결정하는 방법 |
| EP4386768A1 (en) * | 2022-12-13 | 2024-06-19 | Koninklijke Philips N.V. | Active sleep apnea case finding and scheduling system and method of operation thereof |
| US11806334B1 (en) | 2023-01-12 | 2023-11-07 | Bioxcel Therapeutics, Inc. | Non-sedating dexmedetomidine treatment regimens |
| WO2025176701A1 (en) * | 2024-02-19 | 2025-08-28 | Rigshospitalet | Novel pediatric composition of nasal dexmedetomidine |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4407957A (en) | 1981-03-13 | 1983-10-04 | Damon Corporation | Reversible microencapsulation of a core material |
| JPS6058890A (ja) | 1983-09-13 | 1985-04-05 | Mizusawa Ind Chem Ltd | 感熱記録紙用填剤 |
| FI844786A0 (fi) | 1984-12-04 | 1984-12-04 | Farmos Oy | Terapeutiskt utnyttjbar foerening. |
| GB2206880B (en) | 1987-07-16 | 1991-04-24 | Farmos Oy | Optical isomers of an imidazole derivative |
| US5344840A (en) | 1988-02-29 | 1994-09-06 | Orion-Yhtyma Oy | 4-substituted imidazole derivatives useful in perioperative care |
| US5217718A (en) | 1989-08-18 | 1993-06-08 | Cygnus Therapeutic Systems | Method and device for administering dexmedetomidine transdermally |
| US5124157A (en) | 1989-08-18 | 1992-06-23 | Cygnus Therapeutic Systems | Method and device for administering dexmedetomidine transdermally |
| FI894911A0 (fi) | 1989-10-17 | 1989-10-17 | Farmos Oy | En terapeutiskt vaerdefull foerening. |
| US5304569A (en) | 1989-11-13 | 1994-04-19 | Orion-Yhtyma Oy | Compositions and their use in lowering intraocular pressure |
| SG47470A1 (en) | 1991-04-25 | 1998-04-17 | Univ Brown Res Found | Implantable biocompatible immunoisolatory vehicle for delivery of a selected therapeutic products |
| US5383851A (en) | 1992-07-24 | 1995-01-24 | Bioject Inc. | Needleless hypodermic injection device |
| US5569189A (en) | 1992-09-28 | 1996-10-29 | Equidyne Systems, Inc. | hypodermic jet injector |
| ATE220327T1 (de) | 1992-09-29 | 2002-07-15 | Inhale Therapeutic Syst | Pulmonale abgabe von aktiven fragmenten des parathormons |
| GB2281206A (en) | 1993-08-25 | 1995-03-01 | Orion Yhtymae Oy | Use of dexmedetomidine |
| FR2718357B1 (fr) | 1994-04-06 | 1997-10-03 | Defarges Alain Moreau | Perfectionnements apportés à un dispositif d'injection par jet sans aiguille. |
| JP3547755B2 (ja) | 1994-08-08 | 2004-07-28 | デビオファーム・エス・アー | オキサリプラティヌムの医薬的に安定な製剤 |
| US5599302A (en) | 1995-01-09 | 1997-02-04 | Medi-Ject Corporation | Medical injection system and method, gas spring thereof and launching device using gas spring |
| US5780014A (en) | 1995-04-14 | 1998-07-14 | Inhale Therapeutic Systems | Method and apparatus for pulmonary administration of dry powder alpha 1-antitrypsin |
| US5654007A (en) | 1995-06-07 | 1997-08-05 | Inhale Therapeutic Systems | Methods and system for processing dispersible fine powders |
| DE19749724A1 (de) | 1997-11-11 | 1999-06-10 | Gruenenthal Gmbh | Verwendung einer Kombination aus Opioid und alpha-adrenergem Agonisten in Schmerzmitteln |
| US6716867B1 (en) * | 1998-04-01 | 2004-04-06 | Orion Corporation | Use of dexmedetomidine for ICU sedation |
| AR015744A1 (es) * | 1998-04-01 | 2001-05-16 | Orion Corp | Uso de dexmedetomidina para sedacion en terapia intensiva |
| PE20001396A1 (es) | 1999-01-18 | 2000-12-23 | Gruenenthal Chemie | Formulaciones medicamentosas retardadas que contienen una combinacion de un opioide o una sal fisiologicamente tolerables del mismo, un o-agonista |
| GB9913677D0 (en) | 1999-06-11 | 1999-08-11 | Imperial College | Formulation |
| US6806291B1 (en) | 2003-10-09 | 2004-10-19 | The Foundation For The Lsu Health Sciences Center | Analgesic compounds, their synthesis and pharmaceutical compositions containing them |
| US20080308444A1 (en) | 2007-06-13 | 2008-12-18 | Baxter International Inc. | Packaging system and method of alerting a practitioner |
| US20100197694A1 (en) | 2008-08-01 | 2010-08-05 | Gerald Horn | Compositions and methods for treatment of diseases and conditions with increased vascular permeability |
| EP2165706A1 (en) | 2008-09-18 | 2010-03-24 | BioAlliance Pharma | Treating Inflammatory Pain in Mucosa of the Oral Cavity Using Mucosal Prolonged Release Bioadhesive Therapeutic Carriers. |
| US7896843B2 (en) * | 2008-10-15 | 2011-03-01 | Bioquiddity, Inc. | Special purpose fluid dispenser |
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| JP5536661B2 (ja) | 2008-10-30 | 2014-07-02 | 国立大学法人 岡山大学 | 局所麻酔用組成物 |
| EP3305281A1 (en) | 2009-05-15 | 2018-04-11 | Recro Pharma, Inc. | Sublingual dexmedetomidine compositions and methods of use thereof |
| US8410140B2 (en) | 2009-06-01 | 2013-04-02 | The Regents Of The University Of Michigan | Anesthetic methods and compositions |
| WO2011075621A1 (en) | 2009-12-17 | 2011-06-23 | Alpha Synergy Development, Inc. | Compositions and methods for ophthalmic delivery of nasal decongestants |
| FR2959414B1 (fr) | 2010-04-30 | 2016-01-08 | Luc Quintin | Combinaison de molecules aux fins de traitement d'hypotension survenant au cours du choc septique, cardiogenique, ou anaphylactique refractaire, ou hemorragique terminal, apres correction de la volemie et de l'etat de mal asthmatique refractaire |
| US20130096170A1 (en) | 2011-10-14 | 2013-04-18 | Hospira, Inc. | Methods of treating pediatric patients using dexmedetomidine |
| US8242158B1 (en) | 2012-01-04 | 2012-08-14 | Hospira, Inc. | Dexmedetomidine premix formulation |
-
2012
- 2012-01-04 US US13/343,693 patent/US20130096170A1/en not_active Abandoned
- 2012-05-14 US US13/471,403 patent/US8324260B1/en active Active
- 2012-09-27 EP EP12840033.0A patent/EP2766014B1/en not_active Revoked
- 2012-09-27 MX MX2014004548A patent/MX362626B/es active IP Right Grant
- 2012-09-27 WO PCT/US2012/057652 patent/WO2013055528A1/en not_active Ceased
- 2012-09-27 EP EP18181747.9A patent/EP3446691A1/en not_active Withdrawn
- 2012-09-27 BR BR112014008983A patent/BR112014008983A2/pt not_active Application Discontinuation
- 2012-09-27 RS RS20181048A patent/RS57660B1/sr unknown
- 2012-09-27 KR KR1020147012837A patent/KR20140094539A/ko not_active Ceased
- 2012-09-27 LT LTEP12840033.0T patent/LT2766014T/lt unknown
- 2012-09-27 KR KR1020207004550A patent/KR20200019791A/ko not_active Ceased
- 2012-09-27 CA CA2978258A patent/CA2978258A1/en not_active Abandoned
- 2012-09-27 CN CN201280058634.1A patent/CN103957906A/zh active Pending
- 2012-09-27 ES ES12840033.0T patent/ES2685814T3/es active Active
- 2012-09-27 PL PL12840033T patent/PL2766014T3/pl unknown
- 2012-09-27 SI SI201231349T patent/SI2766014T1/sl unknown
- 2012-09-27 CN CN201811538616.9A patent/CN109700806A/zh active Pending
- 2012-09-27 CA CA2851780A patent/CA2851780C/en not_active Expired - Fee Related
- 2012-09-27 KR KR1020197007143A patent/KR20190029775A/ko not_active Ceased
- 2012-09-27 HU HUE12840033A patent/HUE039671T2/hu unknown
- 2012-09-27 DK DK12840033.0T patent/DK2766014T3/en active
- 2012-09-27 AU AU2012321246A patent/AU2012321246C1/en not_active Ceased
- 2012-09-27 JP JP2014535738A patent/JP6270727B2/ja active Active
- 2012-09-27 PT PT12840033T patent/PT2766014T/pt unknown
- 2012-09-27 IN IN996KON2014 patent/IN2014KN00996A/en unknown
- 2012-09-27 HK HK15100803.0A patent/HK1200333A1/xx unknown
- 2012-09-27 HR HRP20181378TT patent/HRP20181378T1/hr unknown
- 2012-12-24 US US13/726,479 patent/US8507542B2/en active Active
- 2012-12-24 US US13/726,496 patent/US9314449B2/en active Active
-
2013
- 2013-08-09 US US13/963,885 patent/US20140005243A1/en not_active Abandoned
-
2014
- 2014-04-10 IL IL232070A patent/IL232070A0/en unknown
-
2015
- 2015-11-16 US US14/942,880 patent/US20160067220A1/en not_active Abandoned
-
2017
- 2017-01-09 IL IL249991A patent/IL249991A0/en unknown
- 2017-07-20 AU AU2017206211A patent/AU2017206211B2/en not_active Ceased
- 2017-09-29 JP JP2017189989A patent/JP6640164B2/ja active Active
-
2018
- 2018-09-04 CY CY181100916T patent/CY1121041T1/el unknown
-
2019
- 2019-05-21 US US16/418,754 patent/US20190269657A1/en not_active Abandoned
- 2019-05-21 AU AU2019203564A patent/AU2019203564A1/en not_active Abandoned
- 2019-12-25 JP JP2019234042A patent/JP2020073529A/ja active Pending
-
2020
- 2020-11-11 US US17/095,391 patent/US20210137891A1/en not_active Abandoned
-
2021
- 2021-10-04 JP JP2021163378A patent/JP2022008828A/ja not_active Withdrawn
-
2023
- 2023-10-23 JP JP2023181585A patent/JP7818561B2/ja active Active
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