CN103957720B - 肠内菌群改善用营养组合物 - Google Patents
肠内菌群改善用营养组合物 Download PDFInfo
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- CN103957720B CN103957720B CN201280059104.9A CN201280059104A CN103957720B CN 103957720 B CN103957720 B CN 103957720B CN 201280059104 A CN201280059104 A CN 201280059104A CN 103957720 B CN103957720 B CN 103957720B
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/19—Dairy proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C19/00—Cheese; Cheese preparations; Making thereof
- A23C19/06—Treating cheese curd after whey separation; Products obtained thereby
- A23C19/068—Particular types of cheese
- A23C19/076—Soft unripened cheese, e.g. cottage or cream cheese
- A23C19/0765—Addition to the curd of additives other than acidifying agents, dairy products, proteins except gelatine, fats, enzymes, microorganisms, NaCl, CaCl2 or KCl; Foamed fresh cheese products
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Polymers & Plastics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2011-262715 | 2011-11-30 | ||
JP2011262715 | 2011-11-30 | ||
PCT/JP2012/080450 WO2013080911A1 (fr) | 2011-11-30 | 2012-11-26 | Composition nutritionnelle pour améliorer la flore intestinale |
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HK (1) | HK1197795A1 (fr) |
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JP6259209B2 (ja) * | 2013-06-17 | 2018-01-10 | 雪印メグミルク株式会社 | コラーゲン産生促進剤 |
JP6259208B2 (ja) * | 2013-06-17 | 2018-01-10 | 雪印メグミルク株式会社 | ヒアルロン酸産生促進剤 |
JP6259207B2 (ja) * | 2013-06-17 | 2018-01-10 | 雪印メグミルク株式会社 | エラスチン産生促進剤 |
CN105705037A (zh) * | 2013-07-31 | 2016-06-22 | 株式会社明治 | 用于抑制肿瘤生长的营养组合物 |
SG11201607600TA (en) | 2014-03-13 | 2016-10-28 | Singapore Ze&Z Internat Pte Ltd | Vaginal composition and use thereof |
JP5816760B1 (ja) * | 2014-06-27 | 2015-11-18 | 花王株式会社 | 固形状組成物 |
SG11201610547WA (en) | 2014-06-27 | 2017-01-27 | Kao Corp | Solid composition |
JP6484975B2 (ja) * | 2014-09-24 | 2019-03-20 | 日油株式会社 | グリセロリン脂質含有粉末および健康食品 |
AR103531A1 (es) * | 2015-01-26 | 2017-05-17 | Int Dehydrated Foods Inc | Composiciones de caldo y su uso como prebióticos |
JP7300243B2 (ja) * | 2015-12-03 | 2023-06-29 | 株式会社明治 | 栄養組成物 |
TW201735942A (zh) * | 2016-01-22 | 2017-10-16 | Meiji Co Ltd | 內毒素之血中移行抑制用組成物 |
JP6325036B2 (ja) * | 2016-08-19 | 2018-05-16 | 株式会社明治 | 抗がん剤に起因する末梢神経障害を改善するための組成物 |
US11925197B2 (en) * | 2016-09-30 | 2024-03-12 | The A2 Milk Company Limited | Beta-caseins and gut microbiota |
CN107095885A (zh) * | 2017-04-28 | 2017-08-29 | 青岛东海药业有限公司 | 酪酸梭菌在制备预防或治疗慢性阻塞性肺疾病制剂中的应用 |
CN109837219B (zh) * | 2017-11-24 | 2020-09-04 | 江南大学 | 一种水解牛乳过敏源β-乳球蛋白蛋白酶的分离纯化及应用 |
JP7209085B2 (ja) * | 2019-06-05 | 2023-01-19 | 森永乳業株式会社 | 組成物 |
CN110897166B (zh) * | 2019-09-30 | 2023-05-09 | 内蒙古伊利实业集团股份有限公司 | 具有促消化功效的含益生菌与酪蛋白磷酸肽的食用组合物 |
KR20230152127A (ko) * | 2021-03-02 | 2023-11-02 | 아를라 푸즈 에이엠비에이 | 알레르기성이 감소된 면역원성 단백질 가수분해물 |
CN115053929B (zh) * | 2022-05-23 | 2024-04-23 | 江西人之初乳品营养有限公司 | 一种适合脂肪肝人群的配方奶粉及其制备 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1044659A (zh) * | 1988-12-23 | 1990-08-15 | 古斯塔夫·鲍诺恩 | 乳清蛋白质组合物,其生产方法及乳清蛋白质组合物的应用 |
CN1858227A (zh) * | 2006-03-17 | 2006-11-08 | 华南理工大学 | 一种促进乳酸菌增殖及发酵产酸的生物活性肽的制备方法 |
CN100393243C (zh) * | 2002-11-22 | 2008-06-11 | 明治乳业株式会社 | 营养组合物 |
WO2011065552A1 (fr) * | 2009-11-30 | 2011-06-03 | 明治乳業株式会社 | Composition nutritionnelle bénéfique pour l'intestin grêle |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2582092B2 (ja) * | 1987-10-09 | 1997-02-19 | 明治乳業株式会社 | 家畜、家禽用飼料組成物 |
JP4375761B2 (ja) * | 1999-08-03 | 2009-12-02 | 雪印乳業株式会社 | ビフィズス菌増殖促進用組成物 |
WO2002045732A1 (fr) * | 2000-12-05 | 2002-06-13 | Kabushiki Kaisha Yakult Honsha | Promoteurs de proliferation pour bifidobacteries intestinales |
EP1281325A1 (fr) * | 2001-07-30 | 2003-02-05 | Societe Des Produits Nestle S.A. | Composition nutritionnelle utilisée dans la prévention de la prolifération bactérienne |
EP1972208A1 (fr) * | 2007-03-16 | 2008-09-24 | Kirin Holdings Kabushiki Kaisha | Composition pour améliorer la flore microbienne intestinale |
JP2011157335A (ja) * | 2010-02-02 | 2011-08-18 | Snowden Co Ltd | 腸内環境改善組成物 |
-
2012
- 2012-11-26 WO PCT/JP2012/080450 patent/WO2013080911A1/fr active Application Filing
- 2012-11-26 CN CN201280059104.9A patent/CN103957720B/zh active Active
- 2012-11-26 JP JP2013547137A patent/JP6234227B2/ja active Active
- 2012-11-26 SG SG11201402693VA patent/SG11201402693VA/en unknown
- 2012-11-26 IN IN3449DEN2014 patent/IN2014DN03449A/en unknown
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Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1044659A (zh) * | 1988-12-23 | 1990-08-15 | 古斯塔夫·鲍诺恩 | 乳清蛋白质组合物,其生产方法及乳清蛋白质组合物的应用 |
CN100393243C (zh) * | 2002-11-22 | 2008-06-11 | 明治乳业株式会社 | 营养组合物 |
CN1858227A (zh) * | 2006-03-17 | 2006-11-08 | 华南理工大学 | 一种促进乳酸菌增殖及发酵产酸的生物活性肽的制备方法 |
WO2011065552A1 (fr) * | 2009-11-30 | 2011-06-03 | 明治乳業株式会社 | Composition nutritionnelle bénéfique pour l'intestin grêle |
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JP6234227B2 (ja) | 2017-11-22 |
CN103957720A (zh) | 2014-07-30 |
IN2014DN03449A (fr) | 2015-06-05 |
JPWO2013080911A1 (ja) | 2015-04-27 |
WO2013080911A1 (fr) | 2013-06-06 |
SG11201402693VA (en) | 2014-09-26 |
HK1197795A1 (zh) | 2015-02-18 |
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