CN103933180A - Medicine for treating ulcerative colitis and preparation method thereof - Google Patents

Abstract

A medicine for treating ulcerative colitis is characterized by being prepared from the following raw materials by weight: 4-12 g of phellodendron, 4-12 g of coptis, 10-30 g of radix astragali, 10-30 g of atractylodes macrocephala, 10-30 g of sophora japonica L., 10-30 g of radix paeoniae alba, 10-30 g of radix glycyrrhizae, 15-25 g of poria cocos, 10-20 g of sanguisorba officinalis, and 4-12 g of banksia rose. The medicine is prepared by cleaning, drying, grinding into powders, screening, refining honey, preparing into a medicine, preparing into medicine pills and the like. The medicine has the advantages of being simple in preparation, convenient to take, substantial in treatment effect, free of toxic and side effects, and low in price, and is especially suitable for treating ulcerative colitis.

Description

A kind of medicine for the treatment of ulcerative colitis and preparation method thereof

Technical field:

The present invention relates to a kind of medicine for the treatment of colitis and preparation method thereof, particularly a kind of medicine for the treatment of ulcerative colitis and preparation method thereof.

Background technology:

Ulcerative colitis is a kind of idiopathic enteritis disease, take chronic, repeatedly recurrence be its feature, be mucous membrane of colon layer and tela submucosa seriality inflammation, pathological changes is first involved rectum conventionally, spreads gradually to total colectomy.Clinical manifestation is diarrhoea, mucopurulent bloody stool, stomachache.Primary disease can betide any age, is more common in 20～40 years old, is also found in child or old age, men and women's sickness rate no significant difference.Primary disease is more American-European rare in China, and the state of an illness is generally lighter, but prevalence is significantly increased in recent years, and serious symptom also often has report.Treating clinically primary disease common medicine is aminosallcylic acid preparation and glucocorticoid, and prolonged and repeated application all has side effect in various degree, and expensive.

Summary of the invention:

Object of the present invention be exactly to provide a kind of make simple, taking convenience, evident in efficacy, have no side effect, the medicine of cheap treatment ulcerative colitis and preparation method thereof.

The object of the present invention is achieved like this: a kind of medicine for the treatment of ulcerative colitis and preparation method thereof, is characterized in that it is the medicine of being made by the raw material of following weight proportioning: Cortex Phellodendri 4～12g, Rhizoma Coptidis 4～12g, the Radix Astragali 10～30g, the Rhizoma Atractylodis Macrocephalae 10～30g, the Flos Sophorae Immaturus 10～30g, the Radix Paeoniae Alba 10～30g, Radix Glycyrrhizae 10～30g, Poria 15～25g, Radix Sanguisorbae 10～20g, the Radix Aucklandiae 4～12g.

Preparation method of the present invention comprises the following steps:

1), clean: by formula claimed in claim 1, raw material is mixed, with clear water, clean up;

2), oven dry is ground into powder and is sieved: cleaned raw material is put into drying baker and dry, then grind into powder, then with 100 object sieves, raw material is sieved, the medicamental pulverata that granule is little filters out, for future use, what granule was large grinds into powder and sieves again, finally reaches the object of sieving;

3), refining Mel: Mel is put into low baking temperature refining for pot, solidifying as maltosemalt sugar shape, not order Jiao who stirs, the addition of Mel is raw-material weight 1 times;

4), make pill: refined honey is mixed and is rubbed by evenly with above-mentioned medicamental pulverata, place about half an hour, again rub by, make the honeyed pill of 6 grams of left and right;

5), make decoction: cleaned raw material is put into drug-decocting appliance (marmite, crock or aluminum pot all can), then add the clean water that meets drinking water standard, amount of water was advisable to soak powder 2～3cm; Enter to decoct front first by drug immersion half an hour, fully fried in order to medicine juice; Then, boil with high heat and use again slow fire instead and decoct, when decocting (decocting into 250～300ml with every dose is as the criterion) about 20 minutes, stop, removing medicinal residues, get decoction.

This invention also can be made into medicamental pulverata electuary, capsule.

Ulcerative colitis is because some the triggering factor in environment may cause that a series of reaction finally causes the generation of this disease.No matter be any reason, the immune system of its meeting human activin, immune system is invaded to external world material and is hit, and this is the beginning of inflammation.Unfortunately, immune system can not closed, and result continues inflammation, or the immune system of body attacks as enemy the related symptoms of then destroying mucous membrane of colon and causing ulcerative colitis by the intestinal mucosa of oneself repeatedly.

The major function of each component of the present invention:

Cortex Phellodendri: heat clearing and damp drying, eliminating fire and detoxication, except hectic fever due to YIN-deficiency clearind deficient heat.For damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity is warded off, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus.

Rhizoma Coptidis: heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood is told nosebleed, conjunctival congestion, toothache, quenches one's thirst, carbuncle furuncle.

The Radix Astragali: benefiting QI for strengthening the superficies, arresting sweating is admittedly de-, holder skin ulcer granulation promoting, inducing diuresis to remove edema.Be used for the treatment of the deficiency of vital energy weak, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, carbuncle is difficult bursts, and burst and do not hold back for a long time, blood deficiency and yellow complexion, interior-heat is quenched one's thirst.

The Rhizoma Atractylodis Macrocephalae: spleen reinforcing, stomach reinforcing, dampness, and in, antiabortive.Control deficient QI of the spleen and stomach, anorexia, asthenia weak breath, deficiency-distension, has loose bowels, phlegm retention, edema, jaundice, arthralgia chiefly caused by damp pathogen, dysuria, dizziness, spontaneous perspiration, nausea is uneasy.

The Flos Sophorae Immaturus: cooling blood for hemostasis, purging liver-fire.Be used for having blood in stool, hemorrhoidal bleeding, dysentery, metrorrhagia, spits blood, epistaxis, liver-heat conjunctival congestion, has a headache dizzy.

The Radix Paeoniae Alba: nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing is received antiperspirant.Cure mainly the breast abdomen pain over the hypochondriac region, dysentery stomachache, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.

Radix Glycyrrhizae: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.

Poria: eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming.Cure mainly dysuria, edema distension, phlegm retention cough with dyspnea, vomiting, malignant histocytosis, has loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful disease such as grade.

Radix Sanguisorbae: cooling blood for hemostasis, eliminating fire and detoxication.Cure mainly hematemesis and epistaxis, hematuria is had blood in stool, metrorrhagia, and hemorrhoidal hamorrhage dysentery, anal fistula, leucorrhea with red and white discharge, carbuncle skin ulcer swells and ache, eczema pudendal pruritus, burn due to hot liquid or fire, worm venom.

The Radix Aucklandiae: warming middle-JIAO to promote flow of QI pain relieving, strengthening the spleen to promote digestion intestinal stasis relieving.Cure mainly feeling of stuffiness in chest hypochondriac pain, abdominal distention, heavy after dysentery, accumulation of food in the stomach and intes tine due to indigestion, vomiting is had loose bowels, colic of cold type stomachache, edema, beriberi.

The invention has the beneficial effects as follows: make simple, taking convenience, evident in efficacy, have no side effect, cheap, there is good antiinflammatory, pain relieving, hemostasis, antipyretic effect.After most of patients takes this medicine, therapeutic effect is obvious, illustrates:

The specific embodiment:

Embodiment 1: take and manufacture pill as example, get Cortex Phellodendri 4g, Rhizoma Coptidis 4g, Radix Astragali 10g, Rhizoma Atractylodis Macrocephalae 10g, Flos Sophorae Immaturus 10g, Radix Paeoniae Alba 10g, Radix Glycyrrhizae 10g, Poria 15g, Radix Sanguisorbae 10g, Radix Aucklandiae 4g; First above-mentioned raw material is mixed, clean up; Again cleaned raw material is put into drying baker and dry, then grind to form graininess, then with 100 object sieves, ground raw material is sieved, the medicine that granule is little filters out, for future use, what granule was large grinds into powder and sieves again, finally reaches the object of sieving; Then 87 grams of Mel are put into low baking temperature refining for pot, solidifying as maltosemalt sugar shape, the not order of stirring is burnt; Finally refined honey is mixed and is rubbed by evenly with above-mentioned medicamental pulverata, place about half an hour, again rub by, make the honeyed pill of 6 grams of left and right.

Embodiment 2: take and manufacture medicamental pulverata electuary as example, get Cortex Phellodendri 8g, Rhizoma Coptidis 8g, Radix Astragali 20g, Rhizoma Atractylodis Macrocephalae 20g, Flos Sophorae Immaturus 20g, Radix Paeoniae Alba 20g, Radix Glycyrrhizae 20g, Poria 20g, Radix Sanguisorbae 15g, Radix Aucklandiae 10g; First above-mentioned raw material is mixed, clean up; Again cleaned raw material being put into drying baker dries, then grind to form graininess, with 100 object sieves, ground raw material is sieved again, the medicine that granule is little filters out, for future use, what granule was large grinds into powder and sieves again, finally reaches the object of sieving, the pack of last Yi6gWei unit.

Embodiment 3: take and manufacture decoction as example, get Cortex Phellodendri 10g, Rhizoma Coptidis 10g, Radix Astragali 25g, Rhizoma Atractylodis Macrocephalae 25g, Flos Sophorae Immaturus 25g, Radix Paeoniae Alba 25g, Radix Glycyrrhizae 25g, Poria 20g, Radix Sanguisorbae 17g, Radix Aucklandiae 10g; First above-mentioned raw material is mixed, clean up; Cleaned raw material is put into drug-decocting appliance (marmite, crock or aluminum pot all can) again, then added the clean water that meets drinking water standard, amount of water was advisable to soak powder 23cm; Enter to decoct front first by drug immersion half an hour, fully fried in order to medicine juice; Then, boil with high heat and use again slow fire instead and decoct, when decocting (decocting into 250～300ml with every dose is as the criterion) about 20 minutes, stop, removing medicinal residues, get decoction.

Embodiment 4: take and manufacture capsule as example, get Cortex Phellodendri 12g, Rhizoma Coptidis 12g, Radix Astragali 30g, Rhizoma Atractylodis Macrocephalae 30g, Flos Sophorae Immaturus 30g, Radix Paeoniae Alba 30g, Radix Glycyrrhizae 30g, Poria 25g, Radix Sanguisorbae 20g, Radix Aucklandiae 12g; First above-mentioned raw material is mixed, clean up; Again cleaned raw material is put into drying baker and dry, then grind to form graininess, then with 100 object sieves, ground raw material is sieved, the medicine that granule is little filters out, for future use, what granule was large grinds into powder and sieves again, finally with 0.5g, incapsulates.

Claims (2)

1. treat medicine of ulcerative colitis and preparation method thereof for one kind, it is characterized in that it is the medicine of being made by the raw material of following weight proportioning: Cortex Phellodendri 4～12g, Rhizoma Coptidis 4～12g, the Radix Astragali 10～30g, the Rhizoma Atractylodis Macrocephalae 10～30g, the Flos Sophorae Immaturus 10～30g, the Radix Paeoniae Alba 10～30g, Radix Glycyrrhizae 10～30g, Poria 15～25g, Radix Sanguisorbae 10～20g, the Radix Aucklandiae 4～12g.

2. treat medicine of ulcerative colitis and preparation method thereof for one kind, it is characterized in that it comprises the following steps:

1), clean: by formula claimed in claim 1, raw material is mixed, with clear water, clean up;

2), oven dry is ground into powder and is sieved: cleaned raw material is put into drying baker and dry, then grind into powder, then with 100 object sieves, raw material is sieved, the medicamental pulverata that granule is little filters out, for future use, what granule was large grinds into powder and sieves again, finally reaches the object of sieving;

3), refining Mel: Mel is put into low baking temperature refining for pot, solidifying as maltosemalt sugar shape, not order Jiao who stirs, the addition of Mel is raw-material weight 1 times;

4), make pill: refined honey is mixed and is rubbed by evenly with above-mentioned medicamental pulverata, place about half an hour, again rub by, make the honeyed pill of 6 grams of left and right;

5), make decoction: cleaned raw material is put into drug-decocting appliance (marmite, crock or aluminum pot all can), then add the clean water that meets drinking water standard, amount of water was advisable to soak powder 2～3cm; Enter to decoct front first by drug immersion half an hour, fully fried in order to medicine juice; Then, boil with high heat and use again slow fire instead and decoct, when decocting (decocting into 250～300ml with every dose is as the criterion) about 20 minutes, stop, removing medicinal residues, get decoction.