CN103919935A - Compound traditional Chinese medicine preparation capable of improving eyesight and preparation method thereof - Google Patents
Compound traditional Chinese medicine preparation capable of improving eyesight and preparation method thereof Download PDFInfo
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- CN103919935A CN103919935A CN201410106047.6A CN201410106047A CN103919935A CN 103919935 A CN103919935 A CN 103919935A CN 201410106047 A CN201410106047 A CN 201410106047A CN 103919935 A CN103919935 A CN 103919935A
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Abstract
The invention discloses a compound traditional Chinese medicine preparation capable of improving eyesight and a preparation method, and relates to a compound traditional Chinese medicine preparation used for treating diminution of vision, which belongs to the traditional Chinese medicine composition field. The composition comprises the following raw materials by weight: 115-125g of American ginseng, 115-125g of radix astragali, 15-25g of leech, 35-45g of stigma croci, 82-92g of glutinous rehmannia, 12-22g of pearl, 82-92g of loofah sponge, 82-92g of Chinese angelica, 115-125g of matrimony vine, 82-92g of cassia seed, 115-125g of radix puerariae and 15-25g of cassia twig. The compound traditional Chinese medicine preparation has the beneficial effects of tonifying Qi and activating blood, and nourishing liver and kidney; traditional Chinese medicines for relaxing vein and improving eyesight enable proper compatibility to reach the effect for treating retinitis, the traditional Chinese medicine preparation has the advantages of strengthening resistance and invigorating spleen, supplementing qi and generating body fluid, nourishing yin, liver and kidney, invigorating energy and invigorate blood circulation, and can treat spleen deficiency, liver and kidney insufficiency and heart-nutriment deficiency. The compound traditional Chinese medicine preparation has the advantages of promoting blood circulation to remove blood stasis, freeing channels, dissipating binds, stimulate blood circulation, clearing liver and removing slight corneal opacity, nourishing yin and clearing heat, enriching blood and activating blood, resisting inflammation and relieving pain; can obviously improve qi deficiency and blood stasis, accelerate blood microcirculation of eyeground retina, improve the blood supply of eyeground retina and eye part, and has the effects of anti-inflammation and analgesia.
Description
Technical field
The present invention relates to a kind of Chinese traditional compound medicine that is used for the treatment of visual deterioration, belong to Chinese prescription field, specifically a kind of compound eyesight-improving Chinese medicine preparation and preparation method.
Background technology
Optic atrophy, is that the factors such as optic nerve fiber ischemia, anoxia cause optical fundus optic nerve fiber degeneration and conduction function obstacle oculopathy, take optical fundus pallor papillae as clinical foundation.Belong to motherland's medical science " optic atrohic blindness " category, head sees < < Dragon Lord book on Chinese herbal medicine through > >, and < < proves criterion seven apertures door > > this disease has been done to extremely detailed discussion thereafter.
Optic atrohic blindness (optic atrophy) is often because of both liver and kidney deficiency, and deficiency of both the heart and spleen causes liver blood to lose supporting, and God Light is gradually lost or because being in a very depressed state, stagnation of QI-blood, the visual deterioration that internal organs closing cause sering stasis blocking to occur, modern clinical often with damp-retention due to hypofunction of the spleen, blood stasis due to qi deficiency and so on deficiency syndrome mingling with excess syndrome card is for common.
Because the modern electronic technology products such as TV, computer, mobile phone, multimedia become indispensable instrument in family life and office appliance, in addition diet is meticulous, the greasy few cellulose of heavy wool is taken in, causing a lot of healths must take in element and be difficult to from food normally picked-up, cause bodily fuctions's disequilibrium, there is abnormal clinical pictures such as subhealth state, cause visual deterioration, even blind.
Summary of the invention
The present invention proposes a kind of compound eyesight-improving Chinese medicine preparation and preparation method, and the factor such as it can prophylactic treatment optic nerve fiber ischemia, anoxia causes optical fundus optic nerve fiber degeneration and conduction function obstacle oculopathy.
For achieving the above object, a kind of compound eyesight-improving Chinese medicine preparation of the present invention, is made by the raw material of following weight: Radix Panacis Quinquefolii 115～125g, the Radix Astragali 115～125g, Hirudo 15～25g, Stigma Croci 35～45g, Radix Rehmanniae 82～92g, Margarita 12～22g, Retinervus Luffae Fructus 82～92g, Radix Angelicae Sinensis 82～92g, Fructus Lycii 115～125g, Semen Cassiae 82～92g, Radix Puerariae 115～125g, Ramulus Cinnamomi 15～25g, Flos Chrysanthemi 13～23g.
Described a kind of compound eyesight-improving Chinese medicine preparation, is made by the raw material of following weight: Radix Panacis Quinquefolii 116～124g, the Radix Astragali 116～124g, Hirudo 16～24g, Stigma Croci 36～44g, Radix Rehmanniae 83～91g, Margarita 13～21g, Retinervus Luffae Fructus 83～91g, Radix Angelicae Sinensis 82～91g, Fructus Lycii 116～124g, Semen Cassiae 83～91g, Radix Puerariae 116～124g, Ramulus Cinnamomi 16～24g, Flos Chrysanthemi 14～22g.
Described a kind of compound eyesight-improving Chinese medicine preparation, is made by the raw material of following weight: Radix Panacis Quinquefolii 120g, Radix Astragali 120g, Hirudo 20g, Stigma Croci 40g, Radix Rehmanniae 87g, Margarita 17g, Retinervus Luffae Fructus 87g, Radix Angelicae Sinensis 87g, Fructus Lycii 120g, Semen Cassiae 87g, Radix Puerariae 120g, Ramulus Cinnamomi 20g, Flos Chrysanthemi 18g.
The preparation method of a kind of compound eyesight-improving Chinese medicine preparation of the present invention is as follows;
1. take raw material, Margarita is ground into separately to fine powder, the Radix Astragali of Radix Panacis Quinquefolii, 1/2 weight, Stigma Croci, Hirudo are dried and pulverize, and cross 100 mesh sieves, collect fine powder and Margarita powder and mix, and coarse powder is standby;
2. the Radix Astragali, Fructus Lycii, Radix Rehmanniae, Radix Angelicae Sinensis, Semen Cassiae, Retinervus Luffae Fructus, Ramulus Cinnamomi eight tastes that remain Radix Puerariae, 1/2 weight decoct with water and extract two to four times, add for the first time 10 times of water gagings and decoct 2h, liang respectively adds 6 times of weight decoctings to four times and boils 1h, merging filtrate, is concentrated into relative density 1.2～1.5(60 ℃) thick paste;
3. the fine powders such as Radix Panacis Quinquefolii and thick paste are mixed, are dried, pulverize, are filled capsule and make altogether 1000, obtain.
The Radix Astragali, Fructus Lycii, Radix Rehmanniae, Radix Angelicae Sinensis, Semen Cassiae, Retinervus Luffae Fructus, Ramulus Cinnamomi eight tastes that 2. described step remains Radix Puerariae, 1/2 weight decoct with water extraction three times.
In described concentration step: merging filtrate, preferably concentrated relative density is 1.4(60 ℃) thick paste.
A kind of compound eyesight-improving Chinese medicine preparation of the present invention and preparation method, the causes of disease such as with Radix Panacis Quinquefolii, Radix Astragali righting spleen invigorating, supplementing QI for promoting the production of body fluid, YIN nourishing Liver and kidney, inrigorating qi and promoting blood circulation is deficient with treatment taste, deficiency of the liver and kindey, the heart-nutriment virtual loss are originally; With ministerial drug Hirudo, Flos Carthami blood circulation promoting and blood stasis dispelling, the eliminating stagnation of stimulating the menstrual flow; With adjuvant drug Semen Cassiae, Retinervus Luffae Fructus, Margarita, the Radix Rehmanniae, Radix Angelicae Sinensis, Fructus Lycii, Radix Puerariae dredge the meridian passage, liver heat removing removing nebula, nourishing YIN and clearing away heat, enrich blood invigorate blood circulation, anti-inflammatory analgesic; So that medicine Ramulus Cinnamomi temperature is led to muscle arteries and veins, activating YANG and prormoting functioning of QI, is drawn the capable beniol warp of all medicines; Monarch, plays the same tune on different musical instruments, and plays altogether strengthening vital QI to eliminate pathogenic factors, blood circulation promoting and blood stasis dispelling, liver heat removing and eyesight improving, promoting the flow of QI-blood by warming the meridian, anti-inflammatory analgesic.
Radix Puerariae, Radix Panacis Quinquefolii, the Radix Astragali, Hirudo blood vessel dilating, can increase organic blood flow volume, and Internal carotid artery injection Radix Puerariae total flavones 0.1～5.0mg/kg can make anesthetized dog cerebrovascular obviously expand, and resistance declines, and blood flow increases, and the larger effect of dosage is more obvious.
Ramulus Cinnamomi contains cinnamic aldehyde, has maincenter and periphery vasorelaxation action, can strengthen blood circulation, and cinnamic aldehyde can make the vasodilation of frog foot web, and Ramulus Cinnamomi can obviously increase coronary flow, improves coronary circulation.
Stigma Croci has the obstructive action of the Peripheral Microcirculation of improvement, and blood flow acceleration, the open number increase of capillary network and hemocyte aggregation extent are alleviated.
Radix Rehmanniae has the effect that promotes liver function recovery; Margarita has liver heat removing except the effect of nebula improving eyesight.
Retinervus Luffae Fructus can enter meridians and have the effect of separating pathogenic heat; Radix Angelicae Sinensis has hematosis.
Semen Cassiae aqueous extract, has certain curative effect to myopia, and effective percentage can reach 80% left and right, and its curative effect is relevant with former vision, former vision 0.1～0.3 cure rate 45.9% and former vision 0.7～0.9 cure rate can reach 93.4%.
A kind of compound eyesight-improving Chinese medicine preparation of the present invention and preparation method, its beneficial effect is: benefiting QI for activating blood circulation, enriching yin and nourishing kidney; Suitably the medicine of compatibility dredging collateral improving eyesight to be to reach the effect for the treatment of retinitis, and righting spleen invigorating, supplementing QI for promoting the production of body fluid, YIN nourishing Liver and kidney, inrigorating qi and promoting blood circulation; Deficient, the deficiency of the liver and kindey for the treatment of taste, the heart-nutriment virtual loss etc.; Blood circulation promoting and blood stasis dispelling, the eliminating stagnation of stimulating the menstrual flow dredge the meridian passage, liver heat removing removing nebula, nourishing YIN and clearing away heat, enrich blood invigorate blood circulation, anti-inflammatory analgesic; Can obviously improve blood stasis due to qi deficiency, accelerate to burst into gorgeous bloom Bulbar conjunctiva microcirculation blood flow, improve ocular blood supply; Also there is antiinflammatory, analgesic effect.
The specific embodiment
Below in conjunction with the technical scheme in the embodiment of the present invention, be clearly and completely described, obviously, described embodiment is only one of them embodiment of the present invention, rather than whole embodiment.Embodiment based in the present invention, those of ordinary skills, not making the every other embodiment obtaining under creative work prerequisite, belong to the scope of protection of the invention.
Embodiment 1
Take Radix Panacis Quinquefolii 115g, Radix Astragali 115g, Hirudo 15g, Stigma Croci 35g, Radix Rehmanniae 82g, Margarita 12g, Retinervus Luffae Fructus 82g, Radix Angelicae Sinensis 82g, Fructus Lycii 115g, Semen Cassiae 82g, Radix Puerariae 115g, Ramulus Cinnamomi 15g, Flos Chrysanthemi 18g, Margarita is ground into separately to fine powder, the Radix Astragali of Radix Panacis Quinquefolii, 1/2 weight, Stigma Croci, Hirudo are dried and pulverize, cross 100 mesh sieves, collect fine powder and Margarita powder and mix, coarse powder is standby; Residue Radix Puerariae, the Radix Astragali of 1/2 weight, Fructus Lycii, Radix Rehmanniae, Radix Angelicae Sinensis, Semen Cassiae, Retinervus Luffae Fructus, Ramulus Cinnamomi eight tastes will decoct with water and extract three times, add for the first time 10 times of water gagings and decoct 2h, second and third time respectively adds 6 times of weight decoctings and boils 1h, merge three times filtrate, be concentrated into relative density 1.2(60 ℃) thick paste; The fine powders such as Radix Panacis Quinquefolii and thick paste are mixed, are dried, pulverize, fill capsule and make altogether 1000, obtain.
Embodiment 2
Take Radix Panacis Quinquefolii 125g, Radix Astragali 125g, Hirudo 25g, Stigma Croci 45g, Radix Rehmanniae 92g, Margarita 22g, Retinervus Luffae Fructus 92g, Radix Angelicae Sinensis 92g, Fructus Lycii 125g, Semen Cassiae 92g, Radix Puerariae 125g, Ramulus Cinnamomi 25g, Flos Chrysanthemi 14g; Preparation method is as embodiment 1.
Embodiment 3
Take Radix Panacis Quinquefolii 120g, Radix Astragali 120g, Hirudo 20g, Stigma Croci 40g, Radix Rehmanniae 87g, Margarita 17g, Retinervus Luffae Fructus 87g, Radix Angelicae Sinensis 87g, Fructus Lycii 120g, Semen Cassiae 87g, Radix Puerariae 120g, Ramulus Cinnamomi 20g, Flos Chrysanthemi 22g; Preparation method is as embodiment 1.
The clinical observation for the treatment of optic atrophy:
1. clinical data:
Physical data: optic atrophy 156 examples, all from outpatient.Be divided at random treatment group and matched group, treatment group 106 examples wherein, 141; Man's 52 examples, female's 54 examples, 31～68 years old age, average 40.9 ± 5.3 years old.Two groups at aspects such as sex, age, the courses of disease, all has comparability.
2. diagnostic criteria: in, Western medicine diagnose standard all adopts the guideline of clinical investigations > > required standard of Ministry of Public Health < < new Chinese medicine treatment optic atrophy.
Standards of Chinese Medical Syndrome Differentiation:
Type of deficiency of both the heart and spleen, disease is seen blurring of vision, and there is optic atrophy pathological changes on optical fundus, and dizziness and blurred vision is unable depending on eyelash, lusterless complexion, mood fidgets due to deficiency, lack of appetite Mental fatigue, light red tongue, thready and rapid pulse.
Liver-kidney yin deficiency, disease is seen blurring of vision, and there is optic atrophy pathological changes on optical fundus, and eyes are dry and astringent, have a dizzy spell, tinnitus and soreness of loins, vexed dreaminess, flushed cheeks night sweat, the few tongue of red tongue, thready and rapid pulse.
Liver qi stagnation type, disease is seen blurring of vision, there is optic atrophy pathological changes on optical fundus, depressed irritated, have a dizzy spell, hypochondriac pain poor appetite, menoxenia or dysmenorrhea, red tongue, white and thin fur, thready and rapid pulse.
3. Therapeutic Method: treatment group product of the present invention, one time 4～5, three times on the one; SHIHUYEGUANG WAN for matched group (honest pharmaceutical factory, Xi'an produces), oral, a 6g, a twice-daily.All take three months as a course for the treatment of for two groups.
4. criterion of therapeutical effect: the standard with reference to the clinical guidance principle > > defined of Ministry of Public Health < < new Chinese medicine treatment optic atrophy is carried out.
Clinical recovery: vision >=1.0, the visual field is normal, or has P-VEP to improve, and simultaneous phenomenon disappears.
Effective-vision progress >=4 row, or the visual field expands >=15 °; If during visual debility 0.1, start at the moment to increase to more than 0.04, primary symptom, inferior disease disappears.
Effectively-vision progress >=2 row, or the visual field expands >=5 °; If during visual debility 0.1, start at the moment to increase to more than 0.02, primary symptom, inferior disease disappears.
Invalid-vision progress less than 2 row, simultaneous phenomenon is unchanged.
5. efficacy result: product of the present invention is treated 106 examples, 141,25 of clinical cures, effective 52, effective 48, total effective rate 100%; Matched group 50 examples, 88,8 of clinical cures, effective 20, effective 16, invalid 44.Two groups of curative effect significant differences.
The foregoing is only preferred embodiment of the present invention, in order to limit the present invention, within the spirit and principles in the present invention not all, any modification of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.
Claims (6)
1. a compound eyesight-improving Chinese medicine preparation, is characterized in that: the raw material by following weight is made: Radix Panacis Quinquefolii 115～125g, the Radix Astragali 115～125g, Hirudo 15～25g, Stigma Croci 35～45g, Radix Rehmanniae 82～92g, Margarita 12～22g, Retinervus Luffae Fructus 82～92g, Radix Angelicae Sinensis 82～92g, Fructus Lycii 115～125g, Semen Cassiae 82～92g, Radix Puerariae 115～125g, Ramulus Cinnamomi 15～25g, Flos Chrysanthemi 13～23g.
2. a kind of compound eyesight-improving Chinese medicine preparation as claimed in claim 1, is characterized in that: the raw material by following weight is made: Radix Panacis Quinquefolii 116～124g, the Radix Astragali 116～124g, Hirudo 16～24g, Stigma Croci 36～44g, Radix Rehmanniae 83～91g, Margarita 13～21g, Retinervus Luffae Fructus 83～91g, Radix Angelicae Sinensis 82～91g, Fructus Lycii 116～124g, Semen Cassiae 83～91g, Radix Puerariae 116～124g, Ramulus Cinnamomi 16～24g, Flos Chrysanthemi 14～22g.
3. a kind of compound eyesight-improving Chinese medicine preparation as claimed in claim 1, is characterized in that: the raw material by following weight is made: Radix Panacis Quinquefolii 120g, Radix Astragali 120g, Hirudo 20g, Stigma Croci 40g, Radix Rehmanniae 87g, Margarita 17g, Retinervus Luffae Fructus 87g, Radix Angelicae Sinensis 87g, Fructus Lycii 120g, Semen Cassiae 87g, Radix Puerariae 120g, Ramulus Cinnamomi 20g, Flos Chrysanthemi 18g.
4. a kind of preparation method of compound eyesight-improving Chinese medicine preparation as described in claims 1 to 3, is characterized in that:
1. take raw material, Margarita is ground into separately to fine powder, the Radix Astragali of Radix Panacis Quinquefolii, 1/2 weight, Stigma Croci, Hirudo are dried and pulverize, and cross 100 mesh sieves, collect fine powder and Margarita powder and mix, and coarse powder is standby;
2. the Radix Astragali, Fructus Lycii, Radix Rehmanniae, Radix Angelicae Sinensis, Semen Cassiae, Retinervus Luffae Fructus, Ramulus Cinnamomi eight tastes that remain Radix Puerariae, 1/2 weight decoct with water and extract two to four times, add for the first time 10 times of water gagings and decoct 2h, liang respectively adds 6 times of weight decoctings to four times and boils 1h, merging filtrate, is concentrated into relative density 1.2～1.5(60 ℃) thick paste;
3. the fine powders such as Radix Panacis Quinquefolii and thick paste are mixed, are dried, pulverize, are filled capsule and make altogether 1000, obtain.
5. a kind of preparation method of compound eyesight-improving Chinese medicine preparation as claimed in claim 4, is characterized in that: the Radix Astragali, Fructus Lycii, Radix Rehmanniae, Radix Angelicae Sinensis, Semen Cassiae, Retinervus Luffae Fructus, Ramulus Cinnamomi eight tastes that 2. described step remains Radix Puerariae, 1/2 weight decoct with water and extract three times.
6. a kind of preparation method of compound eyesight-improving Chinese medicine preparation as claimed in claim 4, is characterized in that: in described concentration step: merging filtrate, preferably concentrated relative density is 1.4(60 ℃) thick paste.
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105267466A (en) * | 2015-10-30 | 2016-01-27 | 方心淳 | Traditional Chinese medicine composition for treating retinitis |
| CN106074899A (en) * | 2016-07-12 | 2016-11-09 | 张明科 | A kind of Chinese medicine composition treating oculopathy and preparation method thereof |
| CN106310094A (en) * | 2016-08-30 | 2017-01-11 | 林海燕 | Pharmaceutical composition for eye treatment |
| CN107669750A (en) * | 2017-11-02 | 2018-02-09 | 韩哲夫 | A kind of formula and preparation method of thousand primary bright eyes cream |
| CN110302191A (en) * | 2019-07-09 | 2019-10-08 | 西安乐健生物科技有限公司 | A kind of pharmaceutical composition based on diplopia ' Yanming ' capsules for clearing and its application in treatment diabetic eye diseases |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1136442A (en) * | 1995-05-24 | 1996-11-27 | 程庆民 | Medicine for improving eyesight |
| CN101601828A (en) * | 2009-03-25 | 2009-12-16 | 夏德昭 | The Chinese medicine of recovering lost eyesight of treatment optic neuritis, optic atrophy |
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2014
- 2014-03-21 CN CN201410106047.6A patent/CN103919935A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1136442A (en) * | 1995-05-24 | 1996-11-27 | 程庆民 | Medicine for improving eyesight |
| CN101601828A (en) * | 2009-03-25 | 2009-12-16 | 夏德昭 | The Chinese medicine of recovering lost eyesight of treatment optic neuritis, optic atrophy |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105267466A (en) * | 2015-10-30 | 2016-01-27 | 方心淳 | Traditional Chinese medicine composition for treating retinitis |
| CN106074899A (en) * | 2016-07-12 | 2016-11-09 | 张明科 | A kind of Chinese medicine composition treating oculopathy and preparation method thereof |
| CN106310094A (en) * | 2016-08-30 | 2017-01-11 | 林海燕 | Pharmaceutical composition for eye treatment |
| CN107669750A (en) * | 2017-11-02 | 2018-02-09 | 韩哲夫 | A kind of formula and preparation method of thousand primary bright eyes cream |
| CN110302191A (en) * | 2019-07-09 | 2019-10-08 | 西安乐健生物科技有限公司 | A kind of pharmaceutical composition based on diplopia ' Yanming ' capsules for clearing and its application in treatment diabetic eye diseases |
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