CN105267466A - Traditional Chinese medicine composition for treating retinitis - Google Patents
Traditional Chinese medicine composition for treating retinitis Download PDFInfo
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- CN105267466A CN105267466A CN201510731725.2A CN201510731725A CN105267466A CN 105267466 A CN105267466 A CN 105267466A CN 201510731725 A CN201510731725 A CN 201510731725A CN 105267466 A CN105267466 A CN 105267466A
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Abstract
A traditional Chinese medicine composition for treating retinitis is made from following components by weight: mulberry fruit 20 g, Chinese Angelica root 15 g, Chinese honeylocust spine 15 g, tuckahoe 15 g, Rhizoma Ligustici Wallichii 9 g, Herba Siegesbeckiae 9 g, flastem milkvetch seed 12 g, white tea 10 g, Semen Plantaginis 10 g, Herba Lycopodii 10 g, Cortex Acanthopanacis 5 g, hawthorn fruit 10 g, Cortex Albiziae 5 g, prepared liquorice root 10 g, white peony root 5 g, sesame leaf 15 g, Radix Platycodi 10 g, Radix Ampelopsis 10 g, and honeysuckle flower 5 g. The traditional Chinese medicine composition is effective in invigorating spleen to eliminate dampness, nourishing liver and kidney, tonifying qi to improve eyesight and activating blood and removing stasis, has exact effect, high acting speed and short treatment course and has no adverse effect.
Description
Technical field
The present invention relates to medical art, be specifically related to a kind of Chinese medicine composition being used for the treatment of central serous chorioretinopathy.
Background technology
Central serous chorioretinopathy or title central serous chorioretinopathy.Primary disease is the isolated exudative chorioretinopathy occurring in macula area, with subretinal Neovascularization and hemorrhage.Primary disease be more common in 20-40 year between twenty and fifty, asexuality difference, how simple eye morbidity.Due to seepage, hemorrhage, the machine of new vessels, finally form cicatrix, make central vision permanent lesion.Cause the reason of primary disease more, many cases may be relevant with tuberculosis, viral infection.At present give antibiotic or sulfa drugs and multivitamin mainly for general disease, in conjunction with vasodilation medicine to remove arteriolospasm, improve microcirculation, improve the toleration organized anoxia.Conventional medicine has rutin, vitamin C, vitamin B complex etc., but the course for the treatment of is long, easily recurs after drug withdrawal, and curative effect is not obvious.
Summary of the invention
It is simple that technical problem to be solved by this invention is to provide a kind of combination, the eutherapeutic Chinese medicine composition being used for the treatment of retinitis.
Technical problem to be solved by this invention realizes by the following technical solutions:
Be used for the treatment of a Chinese medicine composition for retinitis, be made up of the component of following weight: Fructus Mori 20 grams, Radix Angelicae Sinensis 15 grams, Spina Gleditsiae 15 grams, 15 grams, Poria, Rhizoma Chuanxiong 9 Ke, Herba Siegesbeckiae 9 grams, Tong Fructus Tribuli 12 grams, Ramulus et Folium Mussaendae Pubescentis 10 grams, Semen Plantaginis 10 grams, Herba Lycopodii 10g, Cortex Acanthopancis 5g, Fructus Crataegi 10g, Cortex Albiziae 5g, Radix Glycyrrhizae Preparata 10g, Radix Paeoniae Alba 5g, Folium Sesami 15g, Radix Platycodonis 10g, Radix Ampelopsis 10g, Flos Lonicerae 5g.
During preparation, container is put in above-mentioned each component drug mixing, and add water 1000 grams, boil rear little fire and boil 30 minutes again, control out medicinal liquid, clothes with proper temp use, every day 1 dose, sooner or later taking for 2 times points, 15 days is 1 course for the treatment of, generally needs to cure 3 courses for the treatment of.
Fructus Mori: sweet in the mouth, acid, cold in nature; Return liver, kidney channel; Function nourishing YIN and benefiting blood, promote the production of body fluid, intestine moistening.Cure mainly having a dizzy spell of deficiency of the liver and kindey and blood deficiency damage of essence; Soreness of waist tinnitus; Early whitening of beard and hair; Insomnia and dreamful sleep; Tianjin wound is thirsty; Quench one's thirst; Dryness of the intestine constipation.
Radix Angelicae Sinensis: taste sweet, acrid, warm; Return liver, the heart, spleen channel; Function is enriched blood and is invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.
Poria: sweet in the mouth, light is flat; GUIXIN, lung, spleen, kidney channel; Function promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.
Rhizoma Chuanxiong: acrid in the mouth, temperature; Return liver, gallbladder, pericardium channel; Function blood-activating and qi-promoting, wind-expelling pain-stopping.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
Tong Fructus Tribuli: acrid in the mouth, hardship, tepor; Slightly poisonous; Return Liver Channel; Function suppressing the hyperactive liver resolving depression, promoting blood circulation by removing wind, improving eyesight, antipruritic.Dizzy for having a headache, distending pain in the chest and hypochondrium, breast closes acute mastitis, cataract, rubella pruritus.
Semen Plantaginis: sweet in the mouth, cold; Return kidney, urinary bladder channel; Function diuretic, heat clearing away, tomorrow, eliminates the phlegm.Control urinary obstruction, stranguria with turbid discharge, leukorrhagia, hematuria, heat-damp in summer dysentery, cough ant phlegm, arthralgia chiefly caused by damp pathogen, conjunctival congestion is hidden from view.
Central serous chorioretinopathy, Chinese medicine think many and wet hot phlegm turbid in accumulate, the unfavorable or Liver and kidney essence and blood loss in stagnation of QI blood stagnation, profound mansion, heart temper insufficiency of blood is relevant.We have the stagnant effect of row of enriching blood.According to the principle of " normal vision relying on sufficiency of liver-blood ", be incorporated in the treatment atrophy cicatrix that arrives because of blood supply insufficiency of retina and visual disorder comparatively proper.Fructus Mori, Tong Fructus Tribuli are all nourishing essence-blood medicine and enter Liver and kidney.Poria has the effect that QI invigorating is allayed excitement, drying dampness to eliminate phlegm is regulated the flow of vital energy in spleen invigorating, the filth of oozing out so as to reinforcement spleen lung fortune sending up the lucid YANG and excretion absorption macula area and the power of machine compound.The effect of tonify without causing stagnation, unimpeded blood vessels can be played with function with many hematonic, thus reach and improve the object that amphiblestroid microcirculation maintains retina normal physiological function.Semen Plantaginis enters Liver and kidney, can diuretic clearing away heat to improve acuity of vision.Associate with all medicines and dredge drain water and to wet the function of filthy road.
The present composition has carried out a large amount of clinical trials of a large amount of animal acute toxicity tests, long-term toxicity test for animals and disease therapy, drops into the use link of disease therapy provide science and objective foundation to this medicine.Its test method and result of the test are distinguished as follows:
1) animal acute toxicity test is carried out to decoction prepared by the present invention:
Medicine: the crude drug used by the present invention is bought from common Chinese shop and obtained, and its specification meets national Chinese crude drug standard.
Experimental animal: white mice, body weight is at about 50g, and male and female Stochastic choice, is bought by market.
Method and result: get white mice 10, hungry 20 hours, fill with for 5 times by every only every natural gift and feed 50ml, feed one week continuously, observe 10 days, mice is movable normal, non-toxic reaction, without dead.Show that oral liquid is without acute toxicity, clinical medicine dose safety.
2) long-term toxicity test for animals is carried out to decoction prepared by the present invention:
Experimental animal: rat, body weight is at 120-130g, and male and female Stochastic choice, is bought by market.
Method and result: get rat 20, be divided into 2 groups, often organize 10, wherein the 1st group as administration group, feed by filling with for 2 times every every day, each 5-10ml is not etc., 2nd group of diet as a control group, once a day, continuous irrigation is fed 90 days, survey body weight, 24 hours sacrificed by decapitation after last administration, survey blood, routine urinalysis, liver function, renal function, core, the internal organs such as kidney, the change of tissues observed form, observe the effect of dosage, observe diet, movable change, experiment proves that administration group compares without significant change with matched group, equal non-toxic reaction, a kind of safe drugs.
The invention has the beneficial effects as follows: the present invention has effect of invigorating the spleen for eliminating dampness, nourishing the liver and kidney, QI invigorating improving eyesight, blood circulation promoting and blood stasis dispelling, and determined curative effect, instant effect, short treating period, have no adverse reaction.
Detailed description of the invention
The technological means realized to make the present invention, creation characteristic, reaching object and effect is easy to understand, below in conjunction with specific embodiment, setting forth the present invention further.
Embodiment 1
Be used for the treatment of a Chinese medicine composition for retinitis, be made up of the component of following weight: Fructus Mori 20 grams, Radix Angelicae Sinensis 15 grams, Spina Gleditsiae 15 grams, 15 grams, Poria, Rhizoma Chuanxiong 9 Ke, Herba Siegesbeckiae 9 grams, Tong Fructus Tribuli 12 grams, Ramulus et Folium Mussaendae Pubescentis 10 grams, Semen Plantaginis 10 grams, Herba Lycopodii 10g, Cortex Acanthopancis 5g, Fructus Crataegi 10g, Cortex Albiziae 5g, Radix Glycyrrhizae Preparata 10g, Radix Paeoniae Alba 5g, Folium Sesami 15g, Radix Platycodonis 10g, Radix Ampelopsis 10g, Flos Lonicerae 5g.
During preparation, container is put in above-mentioned each component drug mixing, and add water 1000 grams, boil rear little fire and boil 30 minutes again, control out medicinal liquid, clothes with proper temp use, every day 1 dose, sooner or later taking for 2 times points, 15 days is 1 course for the treatment of, generally needs to cure 3 courses for the treatment of.
Treatment standard and therapeutic outcome:
In order to verify clinical efficacy, the routine patient of this prescription random selecting 100, the Chinese medicine preparation of the oral embodiment of the present invention 1, every day potion, decocting divides sooner or later to be taken for twice.Within 15 days, be 1 course for the treatment of, all take 3 courses for the treatment of.
Efficacy determination:
When vision exceedes first visit more than 3 row, reach 1.0-1.5, retina machine compound absorbs, cicatrix unfolds absorption, macula lutea center reflective spot reverts to healing.When vision exceedes first visit 1-5 capable more than, reach about 1.0, retinal exudates absorbs, part cicatrix do not unfold completely, in the non-complete set of center reflective spot, reflective person is effective.1 row when vision exceedes first visit, optical fundus focus has no obvious changer for invalid.
Therapeutic outcome:
This is organized in 100 routine cases and cures 90 examples, effective 7 examples, invalid 3 examples, total effective rate 97%.
Liu so-and-so, female, 25 years old, people from Shou County, Anhui Province.Patient is slight visual deterioration, metamorphopsia, diminishes and accompanies colour vision to change; See light grey muddy in serous detachment district.Take the embodiment of the present invention 1 medicine effective for latter two course for the treatment of, continue to take lasting effects, take again rehabilitation after 3 courses for the treatment of.
Zhang, man, 26 years old, patient is slight visual deterioration, center or paracentral scotoma; Contrast sensitivity reduces.After taking the embodiment of the present invention 1 medicine, a course for the treatment of is effective, continues to take lasting effects, takes again rehabilitation after three courses for the treatment of.
More than show and describe ultimate principle of the present invention and principal character and advantage of the present invention.The technical staff of the industry should understand; the present invention is not restricted to the described embodiments; what describe in above-described embodiment and description just illustrates principle of the present invention; without departing from the spirit and scope of the present invention; the present invention also has various changes and modifications, and these changes and improvements all fall in the claimed scope of the invention.Application claims protection domain is defined by appending claims and equivalent thereof.
Claims (1)
1. be used for the treatment of a Chinese medicine composition for retinitis, be made up of the component of following weight: Fructus Mori 20 grams, Radix Angelicae Sinensis 15 grams, Spina Gleditsiae 15 grams, 15 grams, Poria, Rhizoma Chuanxiong 9 grams, Herba Siegesbeckiae 9 grams, Tong Fructus Tribuli 12 grams, Ramulus et Folium Mussaendae Pubescentis 10 grams, Semen Plantaginis 10 grams, Herba Lycopodii 10g, Cortex Acanthopancis 5g, Fructus Crataegi 10g, Cortex Albiziae 5g, Radix Glycyrrhizae Preparata 10g, Radix Paeoniae Alba 5g, Folium Sesami 15g, Radix Platycodonis 10g, Radix Ampelopsis 10g, Flos Lonicerae 5g.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510731725.2A CN105267466A (en) | 2015-10-30 | 2015-10-30 | Traditional Chinese medicine composition for treating retinitis |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510731725.2A CN105267466A (en) | 2015-10-30 | 2015-10-30 | Traditional Chinese medicine composition for treating retinitis |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101664508A (en) * | 2009-09-18 | 2010-03-10 | 袁宝华 | Drug combination for treating centrality serous chorioretinitis |
| CN102973745A (en) * | 2012-11-30 | 2013-03-20 | 邢强强 | Traditional Chinese medicine composition for treating central retinitis and preparation method thereof |
| CN103919935A (en) * | 2014-03-21 | 2014-07-16 | 西安乐健生物科技有限公司 | Compound traditional Chinese medicine preparation capable of improving eyesight and preparation method thereof |
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2015
- 2015-10-30 CN CN201510731725.2A patent/CN105267466A/en not_active Withdrawn
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101664508A (en) * | 2009-09-18 | 2010-03-10 | 袁宝华 | Drug combination for treating centrality serous chorioretinitis |
| CN102973745A (en) * | 2012-11-30 | 2013-03-20 | 邢强强 | Traditional Chinese medicine composition for treating central retinitis and preparation method thereof |
| CN103919935A (en) * | 2014-03-21 | 2014-07-16 | 西安乐健生物科技有限公司 | Compound traditional Chinese medicine preparation capable of improving eyesight and preparation method thereof |
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Application publication date: 20160127 |