CN103919874B - A kind of Chinese powder medicine treating oral ulcer - Google Patents
A kind of Chinese powder medicine treating oral ulcer Download PDFInfo
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- CN103919874B CN103919874B CN201410150212.8A CN201410150212A CN103919874B CN 103919874 B CN103919874 B CN 103919874B CN 201410150212 A CN201410150212 A CN 201410150212A CN 103919874 B CN103919874 B CN 103919874B
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- radix
- oral ulcer
- alumen
- borneolum syntheticum
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Abstract
A kind of Chinese powder medicine treating oral ulcer, solving pain relieving that the medicine of existing treatment oral ulcer exists, convergence wound surface, antiinflammatory, the undesirable problem of effect of detumescence, its raw material basic composition is: Borneolum Syntheticum, Indigo Naturalis, Alumen, Radix Notoginseng, the Radix Astragali, Flos Lonicerae, Radix Isatidis, Radix Glycyrrhizae, Herba Menthae and Rhizoma Coptidis.Good analgesic effect during this powder treatment oral ulcer, stomatitis, wound surface convergence be fast, can quickly antiinflammatory, detumescence, treatment time is short, adds medicine to and gets final product pain relieving, effective percentage more than 98% for 12 times.
Description
Invention field
The present invention relates to a kind of Chinese powder medicine, be specifically related to a kind of Chinese powder medicine for treating oral ulcer.
Background of invention
Recurrent oral ulceration is modal disease in diseases of oral mucosa.Prevalence occupies the first place of diseases of oral mucosa.
Sircus (1975) investigates 1587 people, and prevalence is 20%；Stomatological Hospital of Beijing Medical Univ. investigates 9463 people, and prevalence is
18.3%.As can be seen here, oral ulcer patient is a colony the hugest.The cause of disease of recurrent oral ulceration is complicated, extremely
The present is the most indefinite, may infect with virus, antibacterial infect and the endocrine regulation of body, immune dysfunction etc. because have
Close.
Herpetic oral ulcer is the oral ulcer caused by herpesvirus, common for herpes simplex oral ulcer,
Though be not as common as recurrent ulcer, but being also the common type of oral ulcer.
The primary treatment measure of oral ulcer includes that local is treated and whole body therapeutic, due to local treatment toxic and side effects relatively
Low, therefore obtain the accreditation of people.The borax of local treatment use, Alumen, the oral cavity ulcer powder of Borneolum Syntheticum, although list in
In Ministry of Public Health standard (WS3-B-0017-89), it is used for treating recurrent oral ulceration, herpetic oral ulcer, determined curative effect, but
Due to reasons such as its mouthfeel, use and local irritations, the compliance of patient is poor, is the most really used widely.
At present, treatment oral ulcer, the drug main BINGPENG SAN to be had of stomatitis, watermelon crystal, KOUKUILING.Above-mentioned all medicines pass through
The clinical treatment of numerous patients, either pain relieving, convergence wound surface, antiinflammatory, detumescence effect the most unsatisfactory, particularly
There is medication repeatedly, the shortcoming of course of disease length.
Summary of the invention
The invention solves the problems that existing treatment oral ulcer, the pain relieving of medicine existence of stomatitis, convergence wound surface, disappear
The problem that effect scorching, detumescence is undesirable, it is provided that a kind of good analgesic effect, wound surface convergence are fast, can quick anti-inflammation detumescence, during treatment
Between short treatment oral ulcer, the Chinese powder medicine of stomatitis.
On the one hand, the present invention relates to a kind of Chinese powder medicine treating oral ulcer, wherein, raw material basic composition is:
Borneolum Syntheticum 2-10g Indigo Naturalis 2-5g Alumen 2-5g Radix Notoginseng 1-5g Radix Astragali 2-6g
Flos Lonicerae 3-6g Radix Isatidis 2-8g Radix Glycyrrhizae 1-5g Herba Menthae 1-3g Rhizoma Coptidis 1-3g.
Some embodiments wherein, the Chinese powder medicine for the treatment of oral ulcer of the present invention, wherein, raw material group substantially
Become:
Borneolum Syntheticum 8g Indigo Naturalis 2.5g Alumen 2.5g Radix Notoginseng 3g Radix Astragali 2g Flos Lonicerae 5g
Radix Isatidis 4g Radix Glycyrrhizae 1.5g Herba Menthae 1g Rhizoma Coptidis 1g
In other embodiments, the Chinese powder medicine for the treatment of oral ulcer of the present invention, wherein, raw material forms substantially
For:
Borneolum Syntheticum 10g Indigo Naturalis 2g Alumen 2g Radix Notoginseng 2g Radix Astragali 3g Flos Lonicerae 6g
Radix Isatidis 5g Radix Glycyrrhizae 1g
Herba Menthae 1g Rhizoma Coptidis 1g.
In other embodiments, the Chinese powder medicine for the treatment of oral ulcer of the present invention, wherein, raw material forms substantially
For:
Borneolum Syntheticum 5g Indigo Naturalis 5g Alumen 5g Radix Notoginseng 2g Radix Astragali 6g
Flos Lonicerae 3g Radix Isatidis 8g Radix Glycyrrhizae 5g Herba Menthae 1g Rhizoma Coptidis 3g.
On the other hand, the present invention relates to the preparation method of a kind of Chinese powder medicine of the present invention, it comprises the steps of:
Take Borneolum Syntheticum, Indigo Naturalis, Alumen are milled to powder；Take Radix Notoginseng, the Radix Astragali, Flos Lonicerae, Radix Isatidis, Radix Glycyrrhizae, Herba Menthae and Rhizoma Coptidis powder
Cross 200 mesh sieves after broken, then mix with the Borneolum Syntheticum grinding composition, Indigo Naturalis and Alumen, i.e. prepare powder, load watering can (dose 2
Gram).
Used in the present invention, herbal nature is as follows:
Borneolum Syntheticum: another name: Borneolum Syntheticum, Borneolum Syntheticum, brain, Borneolum Syntheticum, sheet brain, Borneolum Syntheticum brain, Flos Mume brain, natural Broneolum Syntheticum, old borneol, prunus mume (sieb.) sieb.et zucc.
Sheet.It is mainly composed of in the resin of Borneolum Syntheticum and volatile oil the crystallization obtained, is close to dextro Borneolum Syntheticum purely." book on Chinese herbal medicine guiding principle
Mesh ": " treatment sore throat, headache, nose, toothache, typhoid fever protrusion of the tongue, children's's pox fall into.Logical all keys, dissipate stagnated fire.
Indigo Naturalis: salty, cold.Heat-clearing and toxic substances removing, blood cooling and ecchymoses removing, purging liver-fire, arresting convulsion.For maculae caused by violent heat pathogen, heat in blood tells nosebleed, chest pain
Hemoptysis, aphtha, mumps, sore throat, pediatric epilepsy scared." book on Chinese herbal medicine covers bamboo fish trap ": eliminating pathogen in the liver, only spouting diarrhea, disappear postcibal vomiting phlegm-fire, drives epidemic disease headache, holds back
Typhoid fever also speckle, water is taken after mixing with liquid it.
Alumen: i.e. Potassium aluminum sulfate dodecahydrate, has bacteriostasis." Bencao Jingshu ": Alumen, sour in the mouth gas is cold and nontoxic, its property
Dry anxious astringent therapy, removing toxic substances heat extraction pendant is turbid.Lid cold and heat let out dysentery, the most damp and the hottest do, married woman Bai Wo, how by collapsing, puckery with anti-avulsion therefore also.Cloudy
Erosion malignant boil, the also wet fire of edge, ophthalmalgia is many by wind heat.Except solid heat in the marrow heavily fortified point tooth person, marrow is robbed then sky for heat, and therefore atrophic debility of bones tooth is floating,
Vitriol heat extraction to the marrow, therefore also lead it.Going polyp person in nose, the merit of sterilization heat extraction dampness is also.Alumen, " herbal classic " main cold and heat let out dysentery,
It is more than for a long time that this lid refers to let out dysentery, and lingering diarrhea of collapsing, because having a fever.Vitriol is the most puckery, puckery with anti-avulsion, therefore can master.Vehement in case damp and hot side, long-pending
Stagnant the most, misapply astringent therapy, cause harm and differ, careful it.Married woman Bai Woduo is by collapsing, therefore with astringent therapy with its mark solid, the most non-visits controlling of this.
Ophthalmalgia is not by bulbar conjunctiva polyp and has external oculopathy, the most non-preferably.Except solid heat in the marrow, only can provide it and guide, if calling, it is private, counter damages also.
The dry urgency of vitriol, and water can be robbed, therefore after unfavorable dentary, tooth person's bone therefore also.
Radix Notoginseng: " detailed outline ": hemostasis, dissipates blood, analgesic therapy.Gold sword arrow wound, falls and flutters flogging injury, and blood goes out more than person, chews rotten painting, or is end
Mixing it, its blood i.e. stops.The most main haematemesis, epistaxis, hematochezia, dysentery, metrorrhagia, incessant menorrhea, puerperal stagnant blood not under, blood transport, blood pain, red
Mesh, carbuncle, tiger stings, all diseases of snakebite.
The Radix Astragali: sweet, tepor." Bencao Jingshu ": " function reality table, person does not use pathogenic factor in the exterior；Can help gas, QI excess person does not use；In can
Plug, tonifying for the deficiency, chest and diaphragm is gas-tight asks, the intestines and stomach has stagnant person not use；Energy YANG invigorating, overabundance of YANG leading to deficiency of YIN person avoids it；Part of the body cavity above the diaphragm housing the heart and lungs intenseness of heat, part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels deficiency and coldness
Person avoids it.
Flos Lonicerae: Flos Lonicerae the most just medical value with it is extensive and famous.Its effect is mainly heat-clearing and toxic substances removing,
Cure mainly epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle furunculosis etc..Modern study proves, Flos Lonicerae contains the medicine such as chlorogenic acid, luteolin glycosides
Reason active component, has the various pathogens such as Hemolytic streptococcus, staphylococcus aureus and upper respiratory tract infection Causative virus etc.
Stronger restraint.
Radix Isatidis: bitter, cold, nontoxic.Antipyretic；Maculae caused by violent heat pathogen；High heat headache；Major part pestilence；Crimson tongue is purple dark, and rotten larynx is red
Acute diseases such as cholera and sunstroke；Erysipelas；Mumps；Sore throat；Skin ulcer is swollen, carbuncle；Chickenpox；Measles；Hepatitis；Influenza, epidemic encephalitis, encephalitis b, pneumonia, coma is told
Nosebleed, pharyngeal swelling, acute catarrhal conjunctivitis, skin ulcer rash；Epidemic encephalitis type B, acute, chronic hepatitis, mumps, osteomyelitis can be prevented and treated.
Radix Glycyrrhizae: sweet, flat.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach,
Fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, extremity contraction urgency pain, carbuncle sore tumefacting virus, cushion toxicity, strong.
Herba Menthae: pungent is cool.Reduce phlegm on Qing, sore-throat relieving diaphragm, control wind heat: Herba Menthae end refined honey ball, as Gorgon euryale is big, often hold in the mouth or the eyes a ball.White sand
Also may be used of sugar sum.Controlling scrofula and form a block, pain, wear routed, pus is without cease, disregards distance: Herba Menthae is a branch of as big (drying in the shade) in bowl, soap
Pod ten very (a long chi two cun not moth person, removes casting skin, is coated with vinegar, process make sallow).Smash to pieces, with wine one dry measure used in former times, soak through three places, take out and expose
Dry, more soak three places, so take wine to the greatest extent for spending, dry, it is scattered for smashing sieve, to cook and ball, as Semen Firmianae is big.Often before food, with Huang
20 balls under stilbene soup, children's halves and takes it.(Holy Benevolent Prescriptions Herba Menthae ball)
Rhizoma Coptidis: heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomit acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, heart-fire
High Sheng, dysphoria and insomnia, heat in blood tells nosebleed, conjunctival congestion, and toothache is quenched one's thirst, carbuncle furuncle；External treatment eczema, eczema, auditory meatus is suppurated.Rhizoma Coptidis (processed with wine)
The kind clear part of the body cavity above the diaphragm housing the heart and lungs is burning hot.For conjunctival congestion, aphtha.Prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach stomach function regulating preventing or arresting vomiting.Tying mutually for cold and heat, damp and hot middle resistance, feeling of fullness is vomitted.
Cornel Rhizoma Coptidis soothing liver-QI stomach function regulating preventing or arresting vomiting.For incoordination between the liver and stomach, vomit acid regurgitation.
Detailed description of the invention
The present invention is explained further below in conjunction with embodiment, but the present invention is not done any type of limit by embodiment
Fixed.
Embodiment 1
Drug prescription:
Borneolum Syntheticum 8g Indigo Naturalis 2.5g Alumen 2.5g Radix Notoginseng 3g Radix Astragali 2g Flos Lonicerae 5g
Radix Isatidis 4g Radix Glycyrrhizae 1.5g
Herba Menthae 1g Rhizoma Coptidis 1g.
Preparation method: take Borneolum Syntheticum, Indigo Naturalis, Alumen are milled to powder；Take Radix Notoginseng, the Radix Astragali, Flos Lonicerae, Radix Isatidis, Radix Glycyrrhizae, Herba Menthae
Cross 200 mesh sieves after pulverizing with Rhizoma Coptidis, then mix with the Borneolum Syntheticum grinding composition, Indigo Naturalis and Alumen, i.e. prepare powder, load watering can
(dose 2 grams).
Embodiment 2
Drug prescription:
Borneolum Syntheticum 10g Indigo Naturalis 2g Alumen 2g Radix Notoginseng 2g Radix Astragali 3g
Flos Lonicerae 6g Radix Isatidis 5g Radix Glycyrrhizae 1g
Herba Menthae 1g Rhizoma Coptidis 1g.
Preparation method: take Borneolum Syntheticum, Indigo Naturalis, Alumen are milled to powder；Take Radix Notoginseng, the Radix Astragali, Flos Lonicerae, Radix Isatidis,
Radix Glycyrrhizae, Herba Menthae and Rhizoma Coptidis cross 200 mesh sieves after pulverizing, and then mix with the Borneolum Syntheticum grinding composition, Indigo Naturalis and Alumen, i.e.
Prepare powder, load watering can (dose 2 grams).
Embodiment 3
Drug prescription:
Borneolum Syntheticum 5g Indigo Naturalis 5g Alumen 5g Radix Notoginseng 2g Radix Astragali 6g
Flos Lonicerae 3g Radix Isatidis 8g Radix Glycyrrhizae 5g
Herba Menthae 1g Rhizoma Coptidis 3g.
Preparation method: take Borneolum Syntheticum, Indigo Naturalis, Alumen are milled to powder；Take Radix Notoginseng, the Radix Astragali, Flos Lonicerae, Radix Isatidis,
Radix Glycyrrhizae, Herba Menthae and Rhizoma Coptidis cross 200 mesh sieves after pulverizing, and then mix with the Borneolum Syntheticum grinding composition, Indigo Naturalis and Alumen, i.e.
Prepare powder, load watering can (dose 2 grams).
Clinical trial
The present inventor in January, 2011 so far, 180 example oral ulcer patients are carried out clinical observation treatment.
Therapeutic Method: take after mixing it with water with Chinese powder medicine of the present invention (embodiment 1) boiled water, 3 days is a course for the treatment of, recovers according to the state of an illness
Speed is treated 3-9 days, and according to oral ulcer serious conditions, relatively the lighter, treatment time is the shortest, the state of an illness relatively severe one, treatment effect
The most relatively poor, treatment time is the longest.
Treatment judges:
(1) cure: ulcer heals completely.
(2) take a turn for the better: oral ulcer area reduces.
(3) invalid: symptom is unchanged.
Therapeutic effect: cure 151 examples, take a turn for the better 27 examples, invalid 2 examples, total effective rate more than 98%.
Powder in the embodiment of the present invention 1 compares Comparison of therapeutic such as following table with watermelon crystal:
Powder and watermelon crystal Comparison of therapeutic in table 1 embodiment 1
| Medicament | Case load | Analgesic time | Effectively case | Recovery from illness case | Recovery from illness natural law | Cure rate |
| Embodiment 1 | 180 | 1 day | 178 | 151 | 3 | 98.8% |
| Watermelon crystal | 180 | 3 days | 150 | 135 | 6 | 83.3% |
Model case is illustrated
Zhang, female, 45 years old, suffers from oral ulcer 5 years, is previously used BINGPENG SAN, watermelon crystal, poor effect, use this example
Within after middle powder 6 days, cure, do not recur；
Prunus mume (sieb.) sieb.et zucc., man, 58 years old, suffer from oral ulcer 3, pain is obvious, the most rubescent, uses BINGPENG SAN not take effect, and using should
Recovery from illness on the 2nd after powder in example；
Tang, man, 20 years old, suffers from oral ulcer 2, uses recovery from illness on the 1st after powder in this example；
Tan, female, 32 years old, suffer from oral ulcer 5, pain is obvious, local inflammation, uses watermelon crystal not take effect, uses
Recovery from illness on the 5th after powder in embodiment.
Claims (4)
1. treating a Chinese powder medicine for oral ulcer, wherein, raw material consists of:
Borneolum Syntheticum 2-10g Indigo Naturalis 2-5g Alumen 2-5g Radix Notoginseng 1-5g Radix Astragali 2-6g
Flos Lonicerae 3-6g Radix Isatidis 2-8g Radix Glycyrrhizae 1-5g Herba Menthae 1-3g Rhizoma Coptidis 1-3g.
2., according to the Chinese powder medicine of the treatment oral ulcer described in claim I, wherein, raw material consists of:
Borneolum Syntheticum 8g Indigo Naturalis 2.5g Alumen 2.5g Radix Notoginseng 3g Radix Astragali 2g Flos Lonicerae 5g
Radix Isatidis 4g Radix Glycyrrhizae 1.5g Herba Menthae 1g Rhizoma Coptidis 1g.
The Chinese powder medicine for the treatment of oral ulcer the most according to claim 1, wherein, raw material consists of:
Borneolum Syntheticum 10g Indigo Naturalis 2g Alumen 2g Radix Notoginseng 2g Radix Astragali 3g Flos Lonicerae 6g
Radix Isatidis 5g Radix Glycyrrhizae 1g Herba Menthae 1g Rhizoma Coptidis 1g.
The Chinese powder medicine for the treatment of oral ulcer the most according to claim 1, wherein, raw material consists of:
Borneolum Syntheticum 5g Indigo Naturalis 5g Alumen 5g Radix Notoginseng 2g Radix Astragali 6g Flos Lonicerae 3g
Radix Isatidis 8g Radix Glycyrrhizae 5g Herba Menthae 1g Rhizoma Coptidis 3g.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410150212.8A CN103919874B (en) | 2014-04-14 | 2014-04-14 | A kind of Chinese powder medicine treating oral ulcer |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410150212.8A CN103919874B (en) | 2014-04-14 | 2014-04-14 | A kind of Chinese powder medicine treating oral ulcer |
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| CN103919874A CN103919874A (en) | 2014-07-16 |
| CN103919874B true CN103919874B (en) | 2016-10-26 |
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104623069A (en) * | 2015-02-06 | 2015-05-20 | 苏州市天灵中药饮片有限公司 | Oral ulcer powder and preparation method of oral ulcer powder |
| CN104815040B (en) * | 2015-04-30 | 2017-10-03 | 吉林大学 | Treat the Chinese medicine of canker sore |
| CN106176908A (en) * | 2016-06-29 | 2016-12-07 | 胡剑 | A kind of the tasty and refreshing of oral ulcer for the treatment of dissipates |
| CN108420936A (en) * | 2017-04-19 | 2018-08-21 | 陈甲芳 | A kind of traditional Chinese powder medicine for treating canker sore |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101138622A (en) * | 2007-08-24 | 2008-03-12 | 济南市第三人民医院 | Prescription of mouth ulcer bilayer film and technique of preparing the same |
| CN101259206A (en) * | 2008-04-17 | 2008-09-10 | 张月云 | Medicine for curing oral ulcer |
| CN101822796A (en) * | 2010-03-17 | 2010-09-08 | 山西仟源制药有限公司 | Silver ice buccal tablet, and preparation method and application thereof |
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2014
- 2014-04-14 CN CN201410150212.8A patent/CN103919874B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101138622A (en) * | 2007-08-24 | 2008-03-12 | 济南市第三人民医院 | Prescription of mouth ulcer bilayer film and technique of preparing the same |
| CN101259206A (en) * | 2008-04-17 | 2008-09-10 | 张月云 | Medicine for curing oral ulcer |
| CN101822796A (en) * | 2010-03-17 | 2010-09-08 | 山西仟源制药有限公司 | Silver ice buccal tablet, and preparation method and application thereof |
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