CN101259206A

CN101259206A - Medicine for curing oral ulcer

Info

Publication number: CN101259206A
Application number: CNA2008100890756A
Authority: CN
Inventors: 张月云
Original assignee: Individual
Current assignee: Individual
Priority date: 2008-04-17
Filing date: 2008-04-17
Publication date: 2008-09-10
Anticipated expiration: 2028-04-17
Also published as: CN101259206B

Abstract

The present invention relates to a medicine for curing mouth ulcer. The present invention is made from the raw materials according to the following weight portions: 4 to 8 portions of milk veteh, 3 to 6 portions of angelica, 2 to 5 portions of radix bupleuri, 3 to 6 portions of corktree bark, 0.1 to 1 portions of borneol, 3 to 6 portions of honeysuckle, 2 to 6 portions of nantural oindigo, 1 to 4 portions of white alum, 3 to 7 portions of liquorice and 2 to 6 portions of dwarf lilyturf root. The present invention with simple preparation is obtained by totally grinding the materials and filtering through a 100-mesh screen. By adopting the stickiness of Chinese medicine, the present invention is directly attached to the afflicted part, so as to achieve the curing effect. The medicine for curing mouth ulcer provided by the present invention is a common Chinese medicine with simple prescription, low price, clear curing effect and strong patient adaptability, which is suitable for being widely promoted in clinics.

Description

A kind of medicine for the treatment of oral ulcer

Technical field

The present invention relates to field of medicaments, specifically, relate to a kind of medicine for the treatment of oral ulcer.

Background technology

Oral ulcer is a kind of common disease.Because the oral cavity is the starting point of human body alimentary canal, be subjected to various pathogenic bacterias, virus and mechanical external force infringement easily.Modal is exactly that oral mucosa is impaired, causes oral ulcer, festers, and the lighter influences normal digestive function, weight person even cause such as major diseases such as cancerations.Oral ulcer mainly shows as oral mucosa and isolated, circular or oval shallow-layer aphtha occur, but single-shot or multiple at any position of oral mucosa, and there is the violent sample pain of burning the part.Cold and hot stimulation such as sour-sweet makes all that the pain increased, and is agonizing, influences language, diet, and the course of disease is touching, sends out the author Ke Da several years repeatedly, even many decades, treats rather thornyly, has a strong impact on patient body health and work and study.This disease is the highest disease of diseases of oral mucosa sickness rate, sickness rate in general crowd is not less than 10%, in specific crowd, prevalence can reach 60%, and the women is a little more than the male, but sees so that between twenty and fifty, oral cavity is anterior more, morbidity just is many at 10～20 years old, the no seasonal difference of falling ill, the course of disease has self limiting, but spontaneous recovery in general about 10 days.

For recurrent oral ulceration, in clinical treatment, because of oral cavity state of an illness complexity, symptom different, the easy mistaken diagnosis treatment of patient, the waste that has also brought spiritual misery and financial resources, material resources simultaneously.The common method majority is an anti symptom treatment clinically at present, promptly adopts means such as antiinflammatory, pain relieving and promotion ulcer healing, methods such as control disease multiselect hormone, antibiotic therapy and immunosuppressant, cellulose dissolution.Hormones and antibiotics treatment oral ulcer have had very long history, still are widely used now.Hormone medicine commonly used has kenalog in Orabase, dexamethasone acetate oral cavity sticking tablet, generally is used for the long-term patient who does not more reach recurrence.Antibiotics can be eliminated local inflammation in clinical treatment, the control secondary infection is mainly used in the oral ulcer treatment of acute stage, and the effect of necessarily antibiotic, antiinflammatory and prevention secondary infection is arranged.Some contain hormone and antibiotic compound formulation is more extensive in clinical practice, as hospital preparation oral ulcer ointment, KOUQIANG KUIYANG MO and compound recipe chlortetracycline medicine film etc.But the common side effect of hormone medicine can appear in long-term topical application steroid hormone, as edema, hypertension, bring out and increase the weight of to infect etc.The antibiotics topical application is easy to produce drug resistance, and long-term topical application also can cause dysbacteriosis and fungal infection.As seen, at present unsatisfactory for the therapeutic effect of oral ulcer routine, side effect is bigger, and the relapse rate height often makes patient lose the confidence of treatment.In the weary art of western medical treatment, the traditional Chinese medical science is with its exclusive determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs thought, for the oral ulcer treatment provides sturdy theoretical basis and abundant clinical application data." back to nature ", " green remedy " are accepted by more people with its distinctive curative effect and safety.Therefore the medicine of developing a kind of determined curative effect, convenient and practical treatment oral ulcer is becoming inevitable.

Summary of the invention

The purpose of this invention is to provide a kind of medicine for the treatment of oral ulcer.

In order to realize purpose of the present invention, the invention provides a kind of medicine for the treatment of oral ulcer, it is the medicament of being made according to weight portion by following raw material medicaments: 2～6 parts of 4～8 parts of the Radixs Astragali, 3～6 parts of Radix Angelicae Sinensis, 2～5 parts of Radix Bupleuri, 3～6 parts of Cortex Phellodendris, 0.1～1 part of Borneolum Syntheticum, 3～6 parts of Flos Loniceraes, 2～6 parts of Indigo Naturaliss, 1～4 part of Alumen, 3～7 parts in Radix Glycyrrhizae and Radix Ophiopogonis.

Preferably, the medicine of treatment oral ulcer of the present invention is the medicament of being made according to weight portion by following raw material medicaments: 4 parts of 6 parts of the Radixs Astragali, 5 parts of Radix Angelicae Sinensis, 4 parts of Radix Bupleuri, 4 parts of Cortex Phellodendris, 0.5 part of Borneolum Syntheticum, 6 parts of Flos Loniceraes, 4 parts of Indigo Naturaliss, 2 parts of Alumens, 6 parts in Radix Glycyrrhizae and Radix Ophiopogonis.

Preferably, the medicine of treatment oral ulcer of the present invention is powder or patch.

The preparation of the medicine of treatment oral ulcer of the present invention is very simple, after for example these medicines can being pulverized, sieves and fully mixes, and adds acceptable accessories then and makes.During use, directly the medicine with treatment oral ulcer of the present invention spreads on the ulcer place, utilizes the viscosity of Chinese medicine directly to be bonded at the affected part, arrives the effect of treatment.

The drug prescription of treatment oral ulcer of the present invention is simple, is common Chinese medicine, low price, and curative effect is clear and definite, and patient adaptability is strong, is suitable for large-scale popularization clinically.

The specific embodiment

Below the invention will be further described for the description by the specific embodiment, but this is not to be limitation of the present invention, those skilled in the art are according to basic thought of the present invention, can make various modifications or improvement, but only otherwise break away from basic thought of the present invention, all within the scope of the present invention.

Embodiment 1

Get Radix Astragali 6g, Radix Angelicae Sinensis 5g, Radix Bupleuri 4g, Cortex Phellodendri 4g, Borneolum Syntheticum 0.5g, Flos Lonicerae 6g, Indigo Naturalis 4g, Alumen 2g, Radix Glycyrrhizae 6g and Radix Ophiopogonis 4g, pulverize fully, cross 100 mesh sieves, 10g fully mixes with Icing Sugar, makes the powder of medicine of the present invention.

Experimental example

Trial drug: the powder of the medicine of the present invention of experimental example 1

Using method: once a day, each 3 doses, evenly impose on the affected part, forbid drinking-water, 2 days courses of treatment, 3 courses of treatment half an hour after the medication.

Diagnostic criteria: 1, light-duty oral ulcer: the most common, account for 80%, general diameter 2-4mm, round or oval, clear on every side, isolated being dispersed in, number is few, and each 1～5 is not waited, good sending out in the relatively poor zone of keratinization degree, as lip cheek mucosa, the gum palatine that the keratinization degree is high is less, during outbreak ulcer have " recessed; red; Huang; feature bitterly ", i.e. ulcer concavity, substrate is not hard, periphery is with the congested blush band of about 1mm, and the surface is covered with light yellow pseudomembrane, and the causalgia sense is obvious, infecting serious time companion's submandibular lymph nodes swells and ache, heating generally continues 1-2 week, and the intermission is different in size, because of the thorn Severe Pain influences language, feed, mood, thus quality of life is had a negative impact; 2, heavy oral ulcer: ulcer is big and dark during outbreak, " like the crater " diameter 10-30mm, the dark tela submucosa that reaches is until the flesh layer, and periphery is red and swollen to swell, and the substrate of laying one's hand on is harder, but neat in edge is clear, normal single generation, stage of attack, can reach a month surplus even several months, and pain is heavier, more can stay cicatrix after, rare; 3, herpes sample oral ulcer: ulcer is little, and diameter 2mm can reach more than the dozens of and many, but symptoms such as companioned with headache, low grade fever, general malaise, regional nodes's enlargement are rare.

Criterion of therapeutical effect: pain disappears, the oral ulcer surface healing.

The present invention is through clinical observation case 102 examples, 102 routine oral ulcer patients are adopted outer be coated with drug powder of the present invention, wherein male 50 examples, 43 years old mean age, woman's 52 examples, 38 years old mean age, the result shows: wherein 8 patients cured in one day, and 32 patients cured in two days, 37 patients cured in three days, 16 patients cured in four days, and 9 patients cured total effective rate 100% in five days.Do not see obvious adverse reaction.

Claims

1. medicine for the treatment of oral ulcer is characterized in that it is the medicament of being made according to weight portion by following raw material medicaments: 2～6 parts of 4～8 parts of the Radixs Astragali, 3～6 parts of Radix Angelicae Sinensis, 2～5 parts of Radix Bupleuri, 3～6 parts of Cortex Phellodendris, 0.1～1 part of Borneolum Syntheticum, 3～6 parts of Flos Loniceraes, 2～6 parts of Indigo Naturaliss, 1～4 part of Alumen, 3～7 parts in Radix Glycyrrhizae and Radix Ophiopogonis.

2. the medicine of treatment oral ulcer according to claim 1 is characterized in that it is the medicament of being made according to weight portion by following raw material medicaments: 4 parts of 6 parts of the Radixs Astragali, 5 parts of Radix Angelicae Sinensis, 4 parts of Radix Bupleuri, 4 parts of Cortex Phellodendris, 0.5 part of Borneolum Syntheticum, 6 parts of Flos Loniceraes, 4 parts of Indigo Naturaliss, 2 parts of Alumens, 6 parts in Radix Glycyrrhizae and Radix Ophiopogonis.

3. the medicine of treatment oral ulcer according to claim 1 and 2 is characterized in that described medicament is powder or patch.