A kind of medicament for the treatment of diarrhoea
Technical field
The present invention relates to the digestion field, relate in particular to a kind of medicament for the treatment of diarrhoea.
Background technology
Diarrhoea is a kind of common sympton, refers to that defecation frequency obviously surpasses the frequency of custom on ordinary days, and excrement matter is thin, and moisture increases, and every day, feces volume surpassed 200g, or contains not digest food or pus and blood, mucus.Diarrhoea is often with symptoms such as defecation urgency sense, anus discomfort, incontinences.Diarrhoea is divided acute and chronic two classes.The acute diarrhea morbidity is rapid, and the course of disease is within 2~3 weeks.Chronic diarrhea refer to the course of disease more than two months or the recurrent of intermission in 2~4 weeks suffer from diarrhoea.。
Summary of the invention
The purpose of this invention is to provide a kind of medicament for the treatment of diarrhoea.
In order to realize purpose of the present invention, the invention provides a kind of medicament for the treatment of diarrhoea, it is to be made by following materials by weight: 2~6 parts of Rhizoma Cibotii 3-8 part, 4~8 parts of Pericarpium Citri Reticulataes, 3~6 parts of Semen Euryaless, 2~5 parts of Semen Plantaginiss, 3~6 parts of Herba Taraxacis, 1~10 part of Radix Bupleuri, 3~6 parts of Radix Puerariaes, 2~6 parts of Rhizoma Chuanxiongs, 1~4 part of Herba Houttuyniae, 3~7 parts in Radix Glycyrrhizae and Radix Paeoniae Rubra.
Preferably, the powder for the treatment of of the present invention diarrhoea is to be made by following materials by weight: 4 parts of 5 parts of Rhizoma Cibotiis, 6 parts of Pericarpium Citri Reticulataes, 5 parts of Semen Euryaless, 4 parts of Semen Plantaginiss, 4 parts of Herba Taraxacis, 5 parts of Radix Bupleuri, 6 parts of Radix Puerariaes, 4 parts of Rhizoma Chuanxiongs, 2 parts of Herba Houttuyniae, 6 parts in Radix Glycyrrhizae and Radix Paeoniae Rubra.
Preferably, described medicament can be made tablet, dispersible tablet, powder or capsule.Can adopt method well known to those skilled in the art to carry out medicaments preparation.As required, can add various pharmaceutically acceptable carriers.Described carrier comprises diluent, excipient, filler, binding agent, wetting agent, disintegrating agent, absorption enhancer, surfactant, absorption carrier, lubricant of pharmaceutical field routine etc.Medicament of the present invention in the preparation, selectable filler has: starch, Icing Sugar, calcium phosphate, dextrin, microcrystalline Cellulose, lactose, pregelatinized Starch, mannitol etc.; Selectable binding agent has: sodium carboxymethyl cellulose, PVP-K30, hydroxypropyl cellulose, starch slurry, methylcellulose, ethyl cellulose, hydroxypropyl emthylcellulose, gelling starch etc.; Selectable disintegrating agent has: dried starch, polyvinylpolypyrrolidone, cross-linking sodium carboxymethyl cellulose, carboxymethyl starch sodium, low-substituted hydroxypropyl cellulose etc.; Selectable lubricant has: magnesium stearate, Pulvis Talci, sodium lauryl sulphate, micropowder silica gel etc.
Component of the present invention is simple, with low cost, and therapeutic effect is more satisfactory, for diarrhoea apparent in view therapeutic effect is arranged.
The specific embodiment
Further specify the present invention below by embodiment.It should be understood that embodiments of the invention are for explanation the present invention rather than limitation of the present invention.Essence according to the present invention all belongs to the scope of protection of present invention to the simple modifications that the present invention carries out.
The preparation of embodiment 1 powder
Take by weighing Rhizoma Cibotii 50 grams, Pericarpium Citri Reticulatae 60 grams, Semen Euryales 50 grams, Semen Plantaginis 40 grams, Herba Taraxaci 40 grams, Radix Bupleuri 50 grams, Radix Puerariae 60 grams, Rhizoma Chuanxiong 40 grams, Herba Houttuyniae 20 grams, Radix Glycyrrhizae 60 grams and Radix Paeoniae Rubra 40 grams and fully mix, pulverize, cross 80 mesh sieves.Take by weighing Icing Sugar 250 grams then, cross 80 mesh sieves and above-mentioned raw materials and mix, namely.Gained powder is divided into 100 bags.
Experimental example
Diagnostic criteria
Determine the diagnostic criteria of diarrhea patient according to " internal medicine " (the 2nd edition, the People's Health Publisher publishes): the patient stool is increased, and day reaches 3-5 time, and is very more.The stool color is yellowish, is rare water or egg soup sample.The patient with feel sick, vomiting and in various degree dehydration and electrolyte disturbance.Close patient's 40 examples of the standard of stating of selector, male's 20 examples wherein, women's 20 examples, 23 years old mean age.
Use the powder of the present invention of embodiment 1 preparation to treat, every day twice, each 1 bag, 4 days is a course for the treatment of.
Diagnostic criteria
Produce effects: defecate below 3 times every day in the medication 48h, and that its character is recovered is normal, clinical symptoms and sign disappear.Effectively: defecate below 3 times every day in the medication 96h, and other clinical symptoms and sign alleviate.Invalid: the character of defecating behind the medication 96h, clinical symptoms and sign change not obvious.
Through the treatment of a course for the treatment of, all the patient all meets the standard of produce effects.And in therapeutic process, do not see obvious adverse reaction.