CN102949606A - Chinese medicinal composition for treating female climacteric syndrome - Google Patents
Chinese medicinal composition for treating female climacteric syndrome Download PDFInfo
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Abstract
The invention relates to a Chinese medicinal composition for treating female climacteric syndrome. The Chinese medicinal composition is developed by applying traditional Chinese medical basic theory, and comprises astragalus mongholicus, codonopsis pilosula, Chinese thorowax root, grassleaf sweelflag rhizome, Chinese angelica, white peony root, tree peony bark, hemlock parsley, wheat, liquorice and other Chinese medicinal bulk pharmaceutical chemicals. The Chinese medicinal composition is manufactured into various preparations by virtue of modern conventional preparation methods, and has the effects of replenishing qi to invigorate spleen, nourishing blood and promoting blood circulation, and soothing liver-qi stagnation, and is used for treating a series of climacteric syndromes, such as exhaust and fatigue, palpitation and insomnia and neurasthenia caused by blood and qi deficiency. The Chinese medicinal composition is clinically applied for years, and has a remarkable curative effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of female dimacteric syndrome, more specifically say a kind of have replenishing QI to invigorate the spleen, nourshing blood and promoting blood circulation, dispersing the stagnated live-QI to relieve the stagnation of QI, be used for a series of climacteric syndromes such as spiritlessness and weakness, palpitation and insomnia, neurasthenia due to the QI and blood deficiency.Belong to field of medicaments.
Background technology
Climacteric syndrome is the series of symptoms that is caused by decrease in estrogen.Climacteric women is because hypo-ovaria, hyperpituitarism, the promoting sexual gland hormone of supersecretion, cause the autonomic nervous dysfunction, thereby a series of symptoms in various degree that occur, as menstruation variation, flushed face, cardiopalmus, insomnia, weak, depressed, worry too much, emotional instability, emotional, attention is difficult to concentrate etc., is called " climacteric syndrome ".Most of women are because hypo-ovaria is slower, and body self-regulation and metabolism are enough to adapt to this variation, or light symptoms is only arranged.Minority women is because body can not very fast adaptation, symptom is apparent in view, but it is generally acknowledged, after the women enters into the climacteric period, the variation of family and social environment all can increase the weight of its body ﹠ mind burden, makes climacteric syndrome be easy to occur or makes original existing some sx↑.The unsettled women of some mental status own, climacteric syndrome is just more obvious, even being happy and angry uncertainly.Climacteric syndrome causes the comprehensive syndrome of the sings and symptoms of each tract.Because the aging of human longevity is the important development trend of modern society, so the control of the health care of climacteric women and disease is the vital task that modern medicine faces.
The Therapeutic Method of climacteric syndrome has at present: one, gonadotherapy, i.e. female/progestogen alternative medicine.The method is generally oral estrogen, nilestriol, methyl testosterone etc.But this therapy has very significantly gastrointestinal side effect.Two, pharmacotherapy is namely taken alpha-2 receptor agonist, Beta-3 adrenergic blocker, calmness-antianxiety drug and antidepressant etc.But these medicines only are to come dispenser for a certain symptom of climacteric syndrome, can't play regulating action to conditions of patients on the whole, and the side effect of more double Western medicine is larger, easily involutional women are caused other injury.
On the traditional Chinese medical science climacteric syndrome is belonged to " dirty dry " category, treatment should be to regulate QI and blood, dispersing the stagnated live-QI to relieve the stagnation of QI as main, hold concurrently be careful in one's diet, the partner treatments such as daily life, phychology adjusting.For many years, the traditional Chinese medical science has the medicine for the treatment of climacteric syndrome: climactero tablet, the peaceful ball of climacteric, Gengnianling Capsule, Gengnianshu, FUKANGNING PIAN, comfortable gods etc., great majority are take the kidney invigorating as main.In the market also not take vigorate qi and replenish the blood, dispersing the stagnated live-QI to relieve the stagnation of QI as treating the good medicine of rule.
The Chinese medicine document of relevant treatment climacteric syndrome is as follows in the prior art: 1, CN101099838 discloses a kind of Chinese medicine for the treatment of Women’s climacteric, and it is by Concha Margaritifera 30g, Huai wheat 30g, Radix Codonopsis 15g, Radix Astragali 15g, Radix Bupleuri 10g, Radix Scutellariae 10g, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 10g, Herba Epimedii 12g, Fructus Ligustri Lucidi 12g, Radix Glycyrrhizae Preparata 6g; 2, CN101040913 discloses a kind of health care oral liquid for climacteric syndrome and preparation method thereof, and the component of this health care oral liquid is: Semen sojae atricolor 10-40, Herba Epimedii 3-10, Radix Astragali 3-10, Radix Angelicae Sinensis 3-10, Fructus Mori 1-10, calcium gluconate 0.3-3, Mel 0.1-3; 3, CN101045151 discloses a kind of Chinese medicine composition for the treatment of climacteric syndrome, and take four things as monarch, invigorating the spleen for dissipating phlegm to be mending the day after tomorrow in the side, the LONGMU tranquillizing and allaying excitement, and the Bulbus Lilii Radix Curcumae is with dispersing the stagnated live-QI to relieve the stagnation of QI.Have no at present the relevant report of traditional Chinese medicine composition for treating female dimacteric syndrome of the present invention.
Medicine of the present invention take " replenishing QI to invigorate the spleen, nourshing blood and promoting blood circulation, dispersing the stagnated live-QI to relieve the stagnation of QI " as the Therapeutic Principle, through systematic study, science compatibility, has been developed a kind of Chinese medicine composition for the treatment of female dimacteric syndrome take Chinese medical theory as guidance.
Summary of the invention
Purpose of the present invention just provides a kind of Chinese medicine composition for the treatment of female dimacteric syndrome.
In order to realize purpose of the present invention, the invention provides a kind of Chinese medicine composition for the treatment of female dimacteric syndrome, it is the medicament of being made according to the weight portion meter by following raw materials according: Radix Astragali 10-20 part, Radix Codonopsis 15-25 part, Radix Bupleuri 20-30 part, Rhizoma Acori Graminei 20-30 part, Radix Angelicae Sinensis 10-20 part, Radix Paeoniae Alba 10-20 part, Cortex Moutan 5-15 part, Rhizoma Chuanxiong 10-20 part, Semen Tritici aestivi 15-25 part, Radix Glycyrrhizae 5-10 part.
Preferably, Chinese medicine composition of the present invention is the medicament of being made according to the weight portion meter by following raw materials according: 15 parts of the Radixs Astragali, 20 parts of Radix Codonopsis, 22 parts of Radix Bupleuri, 25 parts of Rhizoma Acori Graminei, 15 parts of Radix Angelicae Sinensis, 16 parts of the Radix Paeoniae Albas, 12 parts of Cortex Moutans, 15 parts of Rhizoma Chuanxiongs, 18 parts of Semen Tritici aestivis, 8 parts in Radix Glycyrrhizae.
Why the present invention selects above-mentioned medical material as raw material, is because they have following effect:
The Radix Astragali: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.It is weak to be used for the deficiency of vital energy, anorexia and loose stool, and sinking of QI of middle-JIAO, the chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, the exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle is difficult bursts, and burst for a long time and do not hold back, the blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.
Radix Codonopsis: invigorating the spleen and replenishing QI, the spleen invigorating lung benefiting is used for deficiency of the spleen and lung, the cardiopalmus of breathing hard, anorexia and loose stool, the dyspnea due to deficiency cough, interior-heat is quenched one's thirst.
Radix Bupleuri: evacuate and bring down a fever soothing liver-QI, yang invigorating.Be used for cold, fever, alternate attack of chill and fever, malaria, distending pain in the chest and hypochondrium, menoxenia, sub-official's prolapsus, proctoptosis.
Rhizoma Acori Graminei: removing dampness appetizing, the eliminating phlegm of having one's ideas straightened out, refreshment Fructus Alpiniae Oxyphyllae.It is not hungry to be used for the gastral cavity painful abdominal mass, mouthful dysentery of keeping silent, coma epilepsy, forgetful deafness.
Radix Angelicae Sinensis: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Be used for blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.
The Radix Paeoniae Alba: suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating.It is dizzy to be used for having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.
Cortex Moutan: clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.Be used for maculae caused by violent heat pathogen, hematemesis and epistaxis, night fever abating at dawn, lossless hectic fever due to YIN-deficiency, the amenorrhea dysmenorrhea, carbuncle sore tumefacting virus falls and pounces on the pain of injury.
Rhizoma Chuanxiong: blood-activating and qi-promoting, wind-expelling pain-stopping.Be used for menoxenia, amenorrhea dysmenorrhea, abdominal mass stomachache, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
Semen Tritici aestivi: nourish heart, kidney tonifying, heat extraction quenches the thirst.Control hysteria, dysphoria with smothery sensation disappears and takes off, and lets out profit, carbuncle, and traumatic hemorrhage is scalded.
Radix Glycyrrhizae: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Be used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Described pharmacy optimization is tablet, capsule, granule.When Chinese medicine composition of the present invention is made preparation, the conventional method production in the existing pharmaceutical field can be adopted, various pharmaceutically acceptable carriers can be added when needing.Described carrier comprises diluent, excipient, filler, binding agent, lubricant, disintegrating agent, promotion absorbent, surfactant of pharmaceutical field routine etc.Chinese medicine composition of the present invention is when making oral formulations, and selectable filler has: starch, Icing Sugar, dextrin, microcrystalline Cellulose, lactose, solubilization starch, mannitol etc.; Selectable binding agent has: sodium carboxymethyl cellulose, starch slurry, ethyl cellulose, gelling starch etc.; Selectable disintegrating agent has: dried starch, polyvinylpolypyrrolidone, cross-linking sodium carboxymethyl cellulose, carboxymethyl starch sodium, the low carboxy-propyl cellulose sodium etc. that replaces; Selectable lubricant has: magnesium stearate, Pulvis Talci, sodium lauryl sulphate, micropowder silica gel etc.
Chinese medicine composition provided by the invention has replenishing QI to invigorate the spleen, nourshing blood and promoting blood circulation, dispersing the stagnated live-QI to relieve the stagnation of QI, is used for a series of climacteric syndromes such as spiritlessness and weakness, palpitation and insomnia, neurasthenia due to the QI and blood deficiency.
The specific embodiment
Below with embodiment pharmaceutical composition of a kind for the treatment of of insomnia patients of the present invention and preparation method thereof is further described; this will help the present invention and effect thereof are further understood; embodiment does not limit protection scope of the present invention, and its protection domain is decided by claim.
The granule of embodiment 1 Chinese medicine composition of the present invention
Used crude drug is Radix Astragali 100g, Radix Codonopsis 150g, Radix Bupleuri 200g, Rhizoma Acori Graminei 200g, Radix Angelicae Sinensis 100g, Radix Paeoniae Alba 100g, Cortex Moutan 50g, Rhizoma Chuanxiong 10g, Semen Tritici aestivi 150g, Radix Glycyrrhizae 50g in the present embodiment;
Its preparation method is:
Get the Radix Astragali, Radix Codonopsis, Radix Bupleuri, Rhizoma Acori Graminei, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Cortex Moutan, Rhizoma Chuanxiong, Semen Tritici aestivi, Radix Glycyrrhizae and add 6 times of water gagings and decoct 2 times, each 2 hours, filter, merging filtrate is condensed into relative density and is 1.10 extractum; Add appropriate amount of starch and granulate, drying, sterilization, granulation 500g gets final product.
The tablet of embodiment 2 Chinese medicine compositions of the present invention
Used crude drug is Radix Astragali 200g, Radix Codonopsis 250g, Radix Bupleuri 300g, Rhizoma Acori Graminei 300g, Radix Angelicae Sinensis 200g, Radix Paeoniae Alba 200g, Cortex Moutan 150g, Rhizoma Chuanxiong 200g, Semen Tritici aestivi 250g, Radix Glycyrrhizae 100g in the present embodiment;
Its preparation method is:
Get the Radix Astragali, Radix Codonopsis, Radix Bupleuri, Rhizoma Acori Graminei, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Cortex Moutan, Rhizoma Chuanxiong, Semen Tritici aestivi, Radix Glycyrrhizae and add 10 times of water gagings and decoct 4 times, each 4 hours, filter, merging filtrate is condensed into relative density and is 1.15 extractum; Add the granulations such as an amount of dextrin, drying, sterilization, tabletting is made 1000, gets final product.
The capsule of embodiment 3 Chinese medicine compositions of the present invention
Used crude drug is Radix Astragali 150g, Radix Codonopsis 200g, Radix Bupleuri 220g, Rhizoma Acori Graminei 250g, Radix Angelicae Sinensis 150g, Radix Paeoniae Alba 160g, Cortex Moutan 120g, Rhizoma Chuanxiong 150g, Semen Tritici aestivi 180g, Radix Glycyrrhizae 80g in the present embodiment;
Its preparation method is:
Get the Radix Astragali, Radix Codonopsis, Radix Bupleuri, Rhizoma Acori Graminei, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Cortex Moutan, Rhizoma Chuanxiong, Semen Tritici aestivi, Radix Glycyrrhizae and add 8 times of water gagings and decoct 3 times, each 3 hours, filter, merging filtrate is condensed into relative density and is 1.12 extractum; Add appropriate amount of starch and granulate, drying, sterilization, filled capsules is made 1000, gets final product.
Chinese medicine composition of the present invention is to the therapeutic effect of female dimacteric syndrome:
Typical case 1: the female dimacteric syndrome patient, Lee, 50 years old, suffer from climacteric syndrome, and with thirsty, insomnia, hypertension, take the granule of embodiment 1, minutes 3 times are oral, and each 10g took 3 months, recovery from illness.
Typical case 2: the female dimacteric syndrome patient, poplar, 56 years old, suffer from climacteric syndrome, and with insomnia, anxiety symptom, take the tablet in the present embodiment 2,3 times on the one, each 4-6 sheet was taken 3 months, recovery from illness.
Typical case 3: the female dimacteric syndrome patient, the king so-and-so, 48 years old, suffer from climacteric syndrome, and with symptoms such as insomnia, thirsty, hypertension, take the capsule among the embodiment 3,3 times on the one, each 4-6 grain was taken 2 months, recovery from illness.
Claims (3)
1. Chinese medicine composition for the treatment of female dimacteric syndrome is characterized in that being prepared from by the crude drug processing of following weight parts:
Radix Astragali 10-20 part Radix Codonopsis 15-25 part Radix Bupleuri 20-30 part Rhizoma Acori Graminei 20-30 part
Radix Angelicae Sinensis 10-20 part Radix Paeoniae Alba 10-20 part Cortex Moutan 5-15 part Rhizoma Chuanxiong 10-20 part
Semen Tritici aestivi 15-25 part Radix Glycyrrhizae 5-10 part.
2. a kind of Chinese medicine composition for the treatment of female dimacteric syndrome according to claim 1 is characterized in that being prepared from by the crude drug processing of following weight parts:
25 parts of 22 parts of Rhizoma Acori Graminei of 20 parts of Radix Bupleuri of 15 parts of Radix Codonopsis of the Radix Astragali
15 parts of 12 parts of Rhizoma Chuanxiongs of 16 parts of Cortex Moutans of 15 portions of Radix Paeoniae Albas of Radix Angelicae Sinensis
8 parts in 18 portions of Radix Glycyrrhizaes of Semen Tritici aestivi.
3. the Chinese medicine composition of one of them described a kind of female dimacteric syndrome according to claim 1 and 2 is characterized in that preparation is capsule, tablet, granule.
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| CN 201110252997 CN102949606A (en) | 2011-08-30 | 2011-08-30 | Chinese medicinal composition for treating female climacteric syndrome |
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| CN 201110252997 CN102949606A (en) | 2011-08-30 | 2011-08-30 | Chinese medicinal composition for treating female climacteric syndrome |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106538787A (en) * | 2016-12-08 | 2017-03-29 | 临沂市源升和金生物科技有限公司 | A kind of Chinese medicinal healthcare tea of preventing and treating female dimacteric syndrome and preparation method thereof |
| CN112245522A (en) * | 2020-11-03 | 2021-01-22 | 平顶山学院 | Traditional Chinese medicine composition and application thereof in medicine for treating insomnia during female perimenopause |
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2011
- 2011-08-30 CN CN 201110252997 patent/CN102949606A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106538787A (en) * | 2016-12-08 | 2017-03-29 | 临沂市源升和金生物科技有限公司 | A kind of Chinese medicinal healthcare tea of preventing and treating female dimacteric syndrome and preparation method thereof |
| CN106538787B (en) * | 2016-12-08 | 2019-11-08 | 临沂市源升和金生物科技有限公司 | A kind of Chinese medicine composition and preparation method thereof for preventing and treating female dimacteric syndrome |
| CN112245522A (en) * | 2020-11-03 | 2021-01-22 | 平顶山学院 | Traditional Chinese medicine composition and application thereof in medicine for treating insomnia during female perimenopause |
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Application publication date: 20130306 |