CN101085306B - Oral administration medicament for treating depression - Google Patents

Oral administration medicament for treating depression Download PDF

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Publication number
CN101085306B
CN101085306B CN2007100161037A CN200710016103A CN101085306B CN 101085306 B CN101085306 B CN 101085306B CN 2007100161037 A CN2007100161037 A CN 2007100161037A CN 200710016103 A CN200710016103 A CN 200710016103A CN 101085306 B CN101085306 B CN 101085306B
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radix
rhizoma
depression
treatment
root
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CN101085306A (en
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王芬
王海锋
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Wang Fen
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Abstract

The invention discloses an oral administration medicament for treating depression, which is prepared from Bupleurum root, hooked uncaria, gastrodia tuber, wild jujuba seeds, poria cocos, root of red rooted saliva, Ligusticum wallichii, cyperus tuber, licorice root, curcuma aromatica, banksia rose, Chinese angelica root, dried orange peel, pinellia tuber, rhizoma corydalis and mongloian snakegourdby a predetermined proportions. The medicament should be decocted in water for the oral dose.

Description

A kind of oral medicine for the treatment of depression
Technical field
The present invention relates to a kind of oral medicine for the treatment of depression, belong to the field of Chinese medicines.
Background technology
Depression claims the melancholia again, is to be a class mental illness of principal character with depressed, and the light-duty patient's appearance of its clinical manifestation is as usual, and heart has painful experience.Slightly Chong people can show as depressed, have a worried look, moan and groan, feel oneself inferior etc., some patient is usually with the neurosis symptom, as: absent minded, hypomnesis, delay of response and, symptom such as insomnia and dreamful sleep.That heavy patients with depression can occur is pessimistic and worldweary, desperate, oneself crime of self-accusation, hallucination vain hope, inappetence, body weight fall sharply, hypofunction and with serious suicidal attempt, even suicide.Human health is constituted a serious threat, therefore must pay much attention to, in time treatment.
The melancholia is a kind of disease that is easy to treat.Almost 80 percent melancholiac can recover normal, happy life through after the appropriate treatment.Therapeutic Method commonly used has: Drug therapy, psychotherapy, sunlight and motion and the living habit formed etc.At present the Drug therapy for depression can adopt medicines such as resist melancholy agent, tranquilizer, sleeping pill, psychosis, but toxic and side effects is big, has certain dependency and costs an arm and a leg.
Summary of the invention
The objective of the invention is to overcome the deficiency of existing treatment, and a kind of oral medicine for the treatment of depression is provided, all select natural Chinese medicinal herb for use, be equipped with suitable psychotherapy and can effectively treat depression.
Technical scheme of the present invention is: the oral medicine of this kind treatment depression, it is characterized in that, make the raw materials of effective components medicine and be: Radix Bupleuri 10~17, Ramulus Uncariae Cum Uncis 15~18, Rhizoma Gastrodiae 10~15, Semen Ziziphi Spinosae 10~15, Poria 10~15, Radix Salviae Miltiorrhizae 15~20, Rhizoma Chuanxiong 9~13, Rhizoma Cyperi 8~15, Radix Glycyrrhizae 5~10, Radix Curcumae 10~20, the Radix Aucklandiae 5~10, Radix Angelicae Sinensis 10~20, Pericarpium Citri Reticulatae 10~15, the Rhizoma Pinelliae 5~10, Rhizoma Corydalis 12~20, Pericarpium Trichosanthis 5~15 by following weight portion.
Preparation and instructions of taking: 1 dose of every day, decocting is mixed well for 2 times, sub-service sooner or later, and serveing on ten days was 1 course of treatment.
Further technical scheme of the present invention is: the oral medicine of this kind treatment depression, it is characterized in that, make the raw materials of effective components medicine and be: Radix Bupleuri 15, Ramulus Uncariae Cum Uncis 18, Rhizoma Gastrodiae 12, Semen Ziziphi Spinosae 12, Poria 12, Radix Salviae Miltiorrhizae 18, Rhizoma Chuanxiong 12, Rhizoma Cyperi 12, Radix Glycyrrhizae 8, Radix Curcumae 15, the Radix Aucklandiae 6, Radix Angelicae Sinensis 15, Pericarpium Citri Reticulatae 12, the Rhizoma Pinelliae 8, Rhizoma Corydalis 15, Pericarpium Trichosanthis 10 by following weight portion.
Preparation and instructions of taking: 1 dose of every day, decocting is mixed well for 2 times, sub-service sooner or later, and serveing on ten days was 1 course of treatment.
Pharmacological action:
Ramulus Uncariae Cum Uncis: heat clearing away suppressing the hyperactive liver, dispelling wind and relieving convulsion.Dizzy, dysphoric cold, diarrhea induced by fright tic, pregnant sub-dysentery, vascular hypertension are used to have a headache.
Radix Bupleuri: hardship is slightly cold.Return liver, gallbladder meridian.Evacuation is brought down a fever, soothing liver-QI, yang invigorating.Be used for cold, fever, alternate attack of chill and fever, malaria, distending pain in the chest and hypochondrium, menoxenia, sub-official's prolapsus, proctoptosis.
Rhizoma Gastrodiae: suppressing the hyperactive liver to relieve the wind syndrome relieving convulsion.It is dizzy to be used to have a headache, numb limbs and tense tendons, infantile convulsion, epilepsy clonus, tetanus.
Semen Ziziphi Spinosae: effects such as nourishing the liver, mind tranquilizing and the heart calming, arresting sweating are arranged.
Poria: sweet, light, flat.GUIXIN, lung, spleen, kidney channel.Promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming, strong lean marrow.Be used for the edema oliguria, the phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in the loose stool, irritability, palpitation with fear insomnia.
Radix Salviae Miltiorrhizae: stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, relieving restlessness clears away heart-fire.Be used for that menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection are swollen and ache, hepatosplenomegaly, angina pectoris.
Rhizoma Chuanxiong: air to open is strongly fragrant, dispeiling pathogenic wind and removing dampness, promoting blood circulation and stopping pain.Control air-cooled headache, revolve dizzyly, the hypochondriac pain abdomen is painful, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation piece pain, ulcer sores.
Rhizoma Cyperi: hot, little hardship, sweet, flat.Return liver, tri-jiao channel.Soothing the liver QI invigorating, promoting blood flow to regulate menstruation.
Radix Glycyrrhizae: and middle emergency, lung moistening, detoxifcation, coordinating the actions of various ingredients in a prescription.Control weakness of the spleen and stomach, lack of appetite, the stomachache loose stool, the overstrain heating, the consumptive lung disease cough, cardiopalmus is fainted from fear.
Radix Curcumae: hot, bitter, cold.Return liver, the heart, lung meridian.Regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice.Be used for the amenorrhea dysmenorrhea, chest and abdomen swelling and pain, twinge, the calentura coma, epilepsy is gone mad, the jaundice dark coloured urine.
The Radix Aucklandiae: hot, bitter, temperature.Return spleen, stomach, large intestine, three warmers, gallbladder meridian.Promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion.Be used for breast gastral cavity distending pain, heavy behind the dysentery, food stagnation does not disappear, anorexia.
Radix Angelicae Sinensis: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Be used for blood deficiency beach wormwood Huang, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.
Pericarpium Citri Reticulatae: bitter, hot, temperature.Return lung, spleen channel.Regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.Be used for fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.
The Rhizoma Pinelliae: drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.
Rhizoma Corydalis: acrid in the mouth, hardship, warm in nature.Promoting blood circulation to remove blood stasis is arranged, promoting the circulation of QI analgesic function.
Pericarpium Trichosanthis: Qinghua heat-phlegm, promoting the circulation of QI the chest stuffiness relieving.Control phlegm-heat cough, costalgia uncomfortable in chest.
The present invention selects the natural Chinese medicines raw material for use, and each reasonable mixture ratio of components is utilized the comprehensive function of the Chinese medicine of respectively distinguishing the flavor of, and depression is had the effect of curing and suppressing, and does not have chemical sweeting agent, and is nontoxic to human body.The oral medicine of this kind treatment depression is selected case through clinical observation for many years, and total effective rate is 96%.Medicine of the present invention can be widely used in the clinical treatment depression.
Model case:
Case one: Song, man, 31 years old, the patient is since in March, 2000, on physiology and occurred some problems mentally, the anxiety of having a sleepless night regularly, sometimes headache, often somehow or other is feared, sees the child place of climbing, will associate him can or can not fall, and can think vividly unexpectedly sometimes, and oneself all can have cold feet at once, the family members gos out, always think the situation that some are bad, in a word, anything all has been imagined as tragedy.The doctor is diagnosed as suffers from depression.Take the medicine of oral medicine course of treatment of this kind treatment depression, just feel that mood is much better significantly after 5 days, sleep also is greatly improved, continue to take 20 days after, just had a headache never again, sleep is all very steady and sure every day, health is also energetically.After adhering to having taken two courses of treatment, all symptoms have all disappeared.
Case two: Chen, the woman, 49 years old, originally the insomnia that the patient occurred since 2004 was not sleep well every several days, a continuous sometimes week all can't fall asleep the whole night afterwards.Eaten 7,8 days sleeping pill, but medicine is once stopping and the person that sleeps not.More and more like flying into a rage, often depressed, be sorely distressed, often expect committing suiside.Seen a lot of doctors depression of all saying so, opened Chinese medicine, but do not had effect.In February, 2006, the classmate has recommended the oral medicine of this kind treatment depression to it, and in the 3rd day evening after the medication, the patient has just slept more than 5 hour, and sensation spirit was much better in second day.Sleep later on all has improvement every day, and after the course of treatment, the patient sleeps and recovered normal, also not irritated, again after treatment drug withdrawal after course of treatment, do not recur.
The specific embodiment
Example one: a kind of oral medicine for the treatment of depression, make the raw materials of effective components medicine and be (unit, gram): Radix Bupleuri 10, Ramulus Uncariae Cum Uncis 15, Rhizoma Gastrodiae 10, Semen Ziziphi Spinosae 10, Poria 10, Radix Salviae Miltiorrhizae 15, Rhizoma Chuanxiong 9, Rhizoma Cyperi 8, Radix Glycyrrhizae 5, Radix Curcumae 10, the Radix Aucklandiae 5, Radix Angelicae Sinensis 10, Pericarpium Citri Reticulatae 10, the Rhizoma Pinelliae 5, Rhizoma Corydalis 12, Pericarpium Trichosanthis 5 by following weight.
Preparation and instructions of taking: 1 dose of every day, decocting is mixed well for 2 times, sub-service sooner or later, and serveing on ten days was 1 course of treatment.
Example two: a kind of oral medicine for the treatment of depression, make the raw materials of effective components medicine and be (unit, gram): Radix Bupleuri 17, Ramulus Uncariae Cum Uncis 18, Rhizoma Gastrodiae 15, Semen Ziziphi Spinosae 15, Poria 15, Radix Salviae Miltiorrhizae 20, Rhizoma Chuanxiong 13, Rhizoma Cyperi 15, Radix Glycyrrhizae 10, Radix Curcumae 20, the Radix Aucklandiae 10, Radix Angelicae Sinensis 20, Pericarpium Citri Reticulatae 15, the Rhizoma Pinelliae 10, Rhizoma Corydalis 20, Pericarpium Trichosanthis 15 by following weight.
Preparation and instructions of taking: with example one.
Example three: a kind of oral medicine for the treatment of depression, make the raw materials of effective components medicine and be (unit, gram): Radix Bupleuri 12, Ramulus Uncariae Cum Uncis 17, Rhizoma Gastrodiae 14, Semen Ziziphi Spinosae 13, Poria 13, Radix Salviae Miltiorrhizae 17, Rhizoma Chuanxiong 12, Rhizoma Cyperi 10, Radix Glycyrrhizae 6, Radix Curcumae 14, the Radix Aucklandiae 8, Radix Angelicae Sinensis 15, Pericarpium Citri Reticulatae 13, the Rhizoma Pinelliae 7, Rhizoma Corydalis 15, Pericarpium Trichosanthis 10 by following weight.
Preparation and instructions of taking: with example one.
Example four: a kind of oral medicine for the treatment of depression, make the raw materials of effective components medicine and be (unit, gram): Radix Bupleuri 17, Ramulus Uncariae Cum Uncis 15, Rhizoma Gastrodiae 10, Semen Ziziphi Spinosae 13, Poria 11, Radix Salviae Miltiorrhizae 20, Rhizoma Chuanxiong 10, Rhizoma Cyperi 8, Radix Glycyrrhizae 9, Radix Curcumae 12, the Radix Aucklandiae 6, Radix Angelicae Sinensis 20, Pericarpium Citri Reticulatae 13, the Rhizoma Pinelliae 8, Rhizoma Corydalis 17, Pericarpium Trichosanthis 14 by following weight.
Preparation and instructions of taking: with example one.
Example five: a kind of oral medicine for the treatment of depression, make the raw materials of effective components medicine and be (unit, gram): Radix Bupleuri 11, Ramulus Uncariae Cum Uncis 18, Rhizoma Gastrodiae 15, Semen Ziziphi Spinosae 15, Poria 12, Radix Salviae Miltiorrhizae 18, Rhizoma Chuanxiong 12, Rhizoma Cyperi 15, Radix Glycyrrhizae 10, Radix Curcumae 12, the Radix Aucklandiae 8, Radix Angelicae Sinensis 17, Pericarpium Citri Reticulatae 13, the Rhizoma Pinelliae 8, Rhizoma Corydalis 12, Pericarpium Trichosanthis 15 by following weight.
Preparation and instructions of taking: with example one.
Example six: a kind of oral medicine for the treatment of depression, make the raw materials of effective components medicine and be (unit, gram): Radix Bupleuri 11, Ramulus Uncariae Cum Uncis 15, Rhizoma Gastrodiae 15, Semen Ziziphi Spinosae 15, Poria 15, Radix Salviae Miltiorrhizae 15, Rhizoma Chuanxiong 10, Rhizoma Cyperi 10, Radix Glycyrrhizae 10, Radix Curcumae 10, the Radix Aucklandiae 10, Radix Angelicae Sinensis 10, Pericarpium Citri Reticulatae 10, the Rhizoma Pinelliae 10, Rhizoma Corydalis 15, Pericarpium Trichosanthis 10 by following weight.
Preparation and instructions of taking: with example one.
Example seven: a kind of oral medicine for the treatment of depression, make the raw materials of effective components medicine and be (unit, gram): Radix Bupleuri 15, Ramulus Uncariae Cum Uncis 18, Rhizoma Gastrodiae 12, Semen Ziziphi Spinosae 12, Poria 12, Radix Salviae Miltiorrhizae 18, Rhizoma Chuanxiong 12, Rhizoma Cyperi 12, Radix Glycyrrhizae 8, Radix Curcumae 15, the Radix Aucklandiae 6, Radix Angelicae Sinensis 15, Pericarpium Citri Reticulatae 12, the Rhizoma Pinelliae 8, Rhizoma Corydalis 15, Pericarpium Trichosanthis 10 by following weight.
Preparation and instructions of taking: with example one.

Claims (2)

1. the Chinese medicine composition of an orally taken for curing depression, it is characterized in that, make the raw materials of effective components medicine and be: Radix Bupleuri 10~17, Ramulus Uncariae Cum Uncis 15~18, Rhizoma Gastrodiae 10~15, Semen Ziziphi Spinosae 10~15, Poria 10~15, Radix Salviae Miltiorrhizae 15~20, Rhizoma Chuanxiong 9~13, Rhizoma Cyperi 8~15, Radix Glycyrrhizae 5~10, Radix Curcumae 10~20, the Radix Aucklandiae 5~10, Radix Angelicae Sinensis 10~20, Pericarpium Citri Reticulatae 10~15, the Rhizoma Pinelliae 5~10, Rhizoma Corydalis 12~20, Pericarpium Trichosanthis 5~15 by following weight portion.
2. the Chinese medicine composition of a kind of orally taken for curing depression according to claim 1, it is characterized in that, make the raw materials of effective components medicine and be: Radix Bupleuri 15, Ramulus Uncariae Cum Uncis 18, Rhizoma Gastrodiae 12, Semen Ziziphi Spinosae 12, Poria 12, Radix Salviae Miltiorrhizae 18, Rhizoma Chuanxiong 12, Rhizoma Cyperi 12, Radix Glycyrrhizae 8, Radix Curcumae 15, the Radix Aucklandiae 6, Radix Angelicae Sinensis 15, Pericarpium Citri Reticulatae 12, the Rhizoma Pinelliae 8, Rhizoma Corydalis 15, Pericarpium Trichosanthis 10 by following weight portion.
CN2007100161037A 2007-06-29 2007-06-29 Oral administration medicament for treating depression Expired - Fee Related CN101085306B (en)

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Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104306678A (en) * 2014-11-07 2015-01-28 韩乃枝 Traditional Chinese medicine preparation for treating postpartum depression and preparation method of traditional Chinese medicine preparation
CN104383440A (en) * 2014-11-11 2015-03-04 李桂亮 Orally-taken pharmaceutical preparation for treating tristimania
CN104435428A (en) * 2014-11-29 2015-03-25 黄根强 Traditional Chinese medicine composition for treating depression
CN105999078A (en) * 2016-06-28 2016-10-12 邓子永 Traditional Chinese medicine preparation for treating depression, capsule and preparation method thereof
CN114796297A (en) * 2022-05-09 2022-07-29 南通大学 Application of elecampane and radix bupleuri composition in preparation of antidepressant
CN115645462A (en) * 2022-11-23 2023-01-31 上海扶岳特生物科技有限公司 Traditional Chinese medicine composition for improving sleep and resisting depression, preparation method and application

Non-Patent Citations (2)

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Title
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李宝玲.抑郁症的中医药研究进展.中医杂志46 9.2001,46(9),566-567. *

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