CN102266482B - Medicament for treating mania - Google Patents
Medicament for treating mania Download PDFInfo
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- CN102266482B CN102266482B CN2011102062761A CN201110206276A CN102266482B CN 102266482 B CN102266482 B CN 102266482B CN 2011102062761 A CN2011102062761 A CN 2011102062761A CN 201110206276 A CN201110206276 A CN 201110206276A CN 102266482 B CN102266482 B CN 102266482B
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Abstract
The invention relates to a medicament for treating mania. The medicament is prepared from the following materials: honeysuckle flower, dwarf lilyturf tuber, rehmannia root, common selfheal fruit-spike, mint, baical skullcap root, Chinese wolfberry, platycodon root, common anemarrhena rhizome, tuckahoe, bryozoatum, liquoric root, lily, arisaema root, red paeony root and grassleaf sweelflag rhizome. The medicament for treating the mania adopts natural materials, is high in safety, and is suitable to be popularized clinically in large scale.
Description
Technical field
The present invention relates to field of medicaments, relate in particular to a kind of medicament of treating mania.
Background technology
Mania is the name of disease on the western medicine, be meant with mental state remarkable and persistent surging be basic clinical, and with corresponding thinking and dystropic one type of mental sickness.The main clinic symptoms of manic state is that mental state is surging, and flight of thought and psychomotor excitement are main.It belongs to the mania syndrome the demented card on traditional Chinese medical science angle.
Clinically at present chemicalses such as lithium carbonate that adopt are treated more, but since the toxic and side effects of chemicals proofread relatively because on therapeutic effect, there are some problems.
Summary of the invention
The purpose of this invention is to provide a kind of medicament of treating mania.
In order to realize the object of the invention; The present invention provides a kind of medicament of treating mania, and it is to be processed by following materials by weight: Flos Lonicerae 3-5 part, Radix Ophiopogonis 1-3 part, Radix Rehmanniae 1-3 part, Spica Prunellae 2-5 part, Herba Menthae 0.1-0.5 part, Radix Scutellariae 1-3 part, Fructus Lycii 2-5 part, Radix Platycodonis 1-3 part, Rhizoma Anemarrhenae 3-5 part, Poria 3-5 part, Pumex 1-3 part, Radix Glycyrrhizae 5-8 part, Bulbus Lilii 1-3 part, Arisaema Cum Bile 1-3 part, Radix Paeoniae Rubra 3-5 part and Rhizoma Acori Graminei 1-3 part.
Preferably, the medicament of treatment mania of the present invention is to be processed by following materials by weight: 1 part of 3 parts of Flos Loniceraes, 2 parts of Radix Ophiopogonis, 3 parts of Radix Rehmanniae, 2 parts of Spica Prunellaes, 0.3 part of Herba Menthae, 2 parts of Radix Scutellariaes, 4 parts of Fructus Lyciis, 2 parts of Radix Platycodoniss, 4 parts of the Rhizoma Anemarrhenaes, 3 parts in Poria, 2 parts of Pumexs, 6 parts in Radix Glycyrrhizae, 2 parts of Bulbus Liliies, 2 parts of Arisaema Cum Bile, 4 parts of Radix Paeoniae Rubra and Rhizoma Acori Graminei.
Preferably, medicament of the present invention can be tablet, dispersible tablet, capsule or decoction.Can adopt method well known to those skilled in the art to carry out preparation of medicaments.As required, can add various pharmaceutically acceptable carriers.Described carrier comprises the conventional diluent of pharmaceutical field, excipient, filler, binding agent, wetting agent, disintegrating agent, absorption enhancer, surfactant, absorption carrier, lubricant etc.Medicament of the present invention in the preparation, selectable filler has: starch, Icing Sugar, calcium phosphate, dextrin, microcrystalline Cellulose, lactose, pregelatinized Starch, mannitol etc.; Selectable binding agent has: sodium carboxymethyl cellulose, PVP-K30, hydroxypropyl cellulose, starch slurry, methylcellulose, ethyl cellulose, hydroxypropyl emthylcellulose, gelling starch etc.; Selectable disintegrating agent has: dried starch, polyvinylpolypyrrolidone, cross-linking sodium carboxymethyl cellulose, carboxymethyl starch sodium, low-substituted hydroxypropyl cellulose etc.; Selectable lubricant has: magnesium stearate, Pulvis Talci, sodium lauryl sulphate, micropowder silica gel etc.
Whole compositions of the medicament of treatment mania of the present invention all are natural materials, and safety is better, are suitable for large-scale promotion clinically.
The specific embodiment
Further specify the present invention through embodiment below.It should be understood that embodiments of the invention are to be used to explain the present invention rather than limitation of the present invention.The simple modifications that essence according to the present invention is carried out the present invention all belongs to the present invention and requires the scope protected.Except as otherwise noted, otherwise the percent among the present invention is percetage by weight.
Embodiment
Take by weighing Flos Lonicerae 30 gram, Radix Ophiopogonis 20 gram, Radix Rehmanniae 30 grams, Spica Prunellae 20 grams, Herba Menthae 3 grams, Radix Scutellariae 20 grams, Fructus Lycii 40 grams, Radix Platycodonis 20 grams, the Rhizoma Anemarrhenae 40 grams, Poria 30 grams, Pumex 20 grams, Radix Glycyrrhizae 60 grams, Bulbus Lilii 20 grams, Arisaema Cum Bile 20 grams, Radix Paeoniae Rubra 40 grams and Rhizoma Acori Graminei 10 grams; Pulverize, cross 80 mesh sieves.Take by weighing Icing Sugar 30 grams then, cross 80 mesh sieves and above-mentioned raw materials and mix.HPMC aqueous solution with 3 weight % is made binding agent system soft material, and granulate (granulating two times) with 16 order nylon mesh, dry 2-3 is individual hour under 60 ℃, with 16 purpose nylon mesh granulate.Add the magnesium stearate of the carboxymethyl starch sodium and 1 gram of 20 grams again, mixing is with 100 of the drift tablettings of diameter 14mm.
Experimental example
One, patient's data
The patient is totally 50 examples, wherein male 25 examples, women 25 examples, 39 years old mean age, average course of disease 2.5 years.Meet Chinese mental sickness classification schemes and diagnostic criteria third edition maniac access diagnostic criteria (classification of Chinese mental disorder is compiled with psychiatric department association of diagnostic criteria CCMD-3 Chinese Medical Association. the 1st edition. Shandong science tech publishing house, 2001; 4 (1): 83-84), manic scale (BRMS) (Zhang Mingyuan chief editor psychiatric department rating scale handbook. the 1st edition. Changsha: Hunan science tech publishing house, 1993:117; 120) scoring is＞18 minutes; There are not serious physical disease, ethanol and substance depilatory, non-anemia of pregnant woman, suckling person.Lab testing blood, routine urinalysis, liver function, electrocardiogram, head CT and the equal Non Apparent Abnormality of X line rabat.
Two, Therapeutic Method
The preparation tablet is treated for above-mentioned patient among the use embodiment, and one day twice, each a slice.With seven days be a course of treatment, carry out two courses of treatment continuously.
Three, efficacy assessment standard (referring to Shen fishing Estate. psychiatry [M]. the 4th edition. Beijing: the People's Health Publisher, 2003.4.)
Recovery from illness: the complete obiteration of psychotic disease symptom, thinking is more normal, is emotionally stable, and it is normal that social function is recovered.Produce effects: manic symptoms is most of to disappear, and thinking is more normal, is emotionally stable, and social function is obviously recovered, and insight partly recovers.Effectively: manic symptoms partly disappears, and thinking is more random, and emotion is stable slightly, and insight partly recovers.Invalid: symptom does not have improvement, no insight.
Four, result
50 routine patients all meet the recovery from illness standard after treating.
Five, untoward reaction
In therapeutic process, carry out tracing observation for 50 routine patients, do not find tangible untoward reaction.
Claims (2)
1. medicament of treating mania; It is characterized in that it is to be processed by following materials by weight: Flos Lonicerae 3-5 part, Radix Ophiopogonis 1-3 part, Radix Rehmanniae 1-3 part, Spica Prunellae 2-5 part, Herba Menthae 0.1-0.5 part, Radix Scutellariae 1-3 part, Fructus Lycii 2-5 part, Radix Platycodonis 1-3 part, Rhizoma Anemarrhenae 3-5 part, Poria 3-5 part, Pumex 1-3 part, Radix Glycyrrhizae 5-8 part, Bulbus Lilii 1-3 part, Arisaema Cum Bile 1-3 part, Radix Paeoniae Rubra 3-5 part and Rhizoma Acori Graminei 1-3 part.
2. the medicament of treatment mania according to claim 1; It is characterized in that it is to be processed by following materials by weight: 1 part of 3 parts of Flos Loniceraes, 2 parts of Radix Ophiopogonis, 3 parts of Radix Rehmanniae, 2 parts of Spica Prunellaes, 0.3 part of Herba Menthae, 2 parts of Radix Scutellariaes, 4 parts of Fructus Lyciis, 2 parts of Radix Platycodoniss, 4 parts of the Rhizoma Anemarrhenaes, 3 parts in Poria, 2 parts of Pumexs, 6 parts in Radix Glycyrrhizae, 2 parts of Bulbus Liliies, 2 parts of Arisaema Cum Bile, 4 parts of Radix Paeoniae Rubra and Rhizoma Acori Graminei.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011102062761A CN102266482B (en) | 2011-07-22 | 2011-07-22 | Medicament for treating mania |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011102062761A CN102266482B (en) | 2011-07-22 | 2011-07-22 | Medicament for treating mania |
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| CN102266482A CN102266482A (en) | 2011-12-07 |
| CN102266482B true CN102266482B (en) | 2012-08-22 |
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| CN2011102062761A Expired - Fee Related CN102266482B (en) | 2011-07-22 | 2011-07-22 | Medicament for treating mania |
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| CN105535447A (en) * | 2016-03-05 | 2016-05-04 | 宁波高新区苗姑养生科技有限公司 | Healthcare pillow capable of preventing and treating heart-liver-kidney deficiency type mania |
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| CN101947285B (en) * | 2010-08-30 | 2012-01-04 | 刘利霞 | Buccal tablet for treating chronic pharyngitis |
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Non-Patent Citations (6)
| Title |
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| 丁德正.涤痰化瘀理神汤在精神疾病治疗中的运用.《河北中医》.1998,第20卷(第03期),157-158. |
| 中西医结合治疗抑郁症;李清亚等;《现代中西医结合杂志》;20070920;第16卷(第27期);4090-4092 * |
| 中西医结合治疗神经症65 例;李根起;《河北中医》;20000831;第22卷(第8期);618-619 * |
| 李根起.中西医结合治疗神经症65 例.《河北中医》.2000,第22卷(第8期),618-619. |
| 李清亚等.中西医结合治疗抑郁症.《现代中西医结合杂志》.2007,第16卷(第27期),4090-4092. |
| 涤痰化瘀理神汤在精神疾病治疗中的运用;丁德正;《河北中医》;19980515;第20卷(第03期);157-158 * |
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| CN102266482A (en) | 2011-12-07 |
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