CN102552511A - Medicament for treating diarrhea - Google Patents
Medicament for treating diarrhea Download PDFInfo
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- CN102552511A CN102552511A CN2012100788129A CN201210078812A CN102552511A CN 102552511 A CN102552511 A CN 102552511A CN 2012100788129 A CN2012100788129 A CN 2012100788129A CN 201210078812 A CN201210078812 A CN 201210078812A CN 102552511 A CN102552511 A CN 102552511A
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- 206010012735 Diarrhoea Diseases 0.000 title abstract description 11
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- 239000000843 powder Substances 0.000 claims description 6
- UAJTZZNRJCKXJN-UHFFFAOYSA-M sodium;2-dodecoxy-2-oxoethanesulfonate Chemical compound [Na+].CCCCCCCCCCCCOC(=O)CS([O-])(=O)=O UAJTZZNRJCKXJN-UHFFFAOYSA-M 0.000 claims description 5
- 241000219780 Pueraria Species 0.000 claims description 4
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- 241000675108 Citrus tangerina Species 0.000 abstract 1
- 244000268590 Euryale ferox Species 0.000 abstract 1
- 235000013717 Houttuynia Nutrition 0.000 abstract 1
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- 240000001949 Taraxacum officinale Species 0.000 abstract 1
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- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 2
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- LNAZSHAWQACDHT-XIYTZBAFSA-N (2r,3r,4s,5r,6s)-4,5-dimethoxy-2-(methoxymethyl)-3-[(2s,3r,4s,5r,6r)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxy-6-[(2r,3r,4s,5r,6r)-4,5,6-trimethoxy-2-(methoxymethyl)oxan-3-yl]oxyoxane Chemical compound CO[C@@H]1[C@@H](OC)[C@H](OC)[C@@H](COC)O[C@H]1O[C@H]1[C@H](OC)[C@@H](OC)[C@H](O[C@H]2[C@@H]([C@@H](OC)[C@H](OC)O[C@@H]2COC)OC)O[C@@H]1COC LNAZSHAWQACDHT-XIYTZBAFSA-N 0.000 description 1
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- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 1
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- 241000600871 Euryale <brittle star> Species 0.000 description 1
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- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 206010021639 Incontinence Diseases 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 229930195725 Mannitol Natural products 0.000 description 1
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- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 description 1
- 229920003081 Povidone K 30 Polymers 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 1
- 239000004141 Sodium laurylsulphate Substances 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 201000009840 acute diarrhea Diseases 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
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- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000001506 calcium phosphate Substances 0.000 description 1
- 229910000389 calcium phosphate Inorganic materials 0.000 description 1
- 235000011010 calcium phosphates Nutrition 0.000 description 1
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 description 1
- 208000019902 chronic diarrheal disease Diseases 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 238000004132 cross linking Methods 0.000 description 1
- 230000013872 defecation Effects 0.000 description 1
- 230000018044 dehydration Effects 0.000 description 1
- 238000006297 dehydration reaction Methods 0.000 description 1
- 235000019425 dextrin Nutrition 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- FPAFDBFIGPHWGO-UHFFFAOYSA-N dioxosilane;oxomagnesium;hydrate Chemical compound O.[Mg]=O.[Mg]=O.[Mg]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O FPAFDBFIGPHWGO-UHFFFAOYSA-N 0.000 description 1
- 239000003937 drug carrier Substances 0.000 description 1
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- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 239000001253 polyvinylpolypyrrolidone Substances 0.000 description 1
- 229920000523 polyvinylpolypyrrolidone Polymers 0.000 description 1
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- 239000004094 surface-active agent Substances 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
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- 239000000080 wetting agent Substances 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a medicament for treating diarrhea. The medicament is prepared from the following Chinese herbal medicines in part by weight: 3 to 8 parts of cibotium root, 4 to 8 parts of tangerine peel, 3 to 6 parts of gordon euryale seed, 2 to 5 parts of plantain seed, 3 to 6 parts of mongolian dandelion herb, 1 to 10 parts of bupleurum, 3 to 6 parts of kudzuvine root, 2 to 6 parts of szechuan lovage rhizome, 1 to 4 parts of heartleaf houttuynia herb, 3 to 7 parts of liquoric root and 2 to 6 parts of red paeony root. The medicament is simple in components and low in cost, has an ideal treatment effect, and has an obvious treatment effect on diarrhea.
Description
Technical field
The present invention relates to the digestion field, relate in particular to a kind of treatment diarrheal medicament.
Background technology
Diarrhoea is a kind of common sympton, is meant that defecation frequency obviously surpasses the frequency of custom on ordinary days, and excrement matter is thin, and moisture increases, and every day, feces volume surpassed 200g, or contains not digest food or pus and blood, mucus.Diarrhoea is often with symptoms such as defecation urgency sense, anus discomfort, incontinences.Diarrhoea is divided acute and chronic two types.The acute diarrhea morbidity is rapid, and the course of disease is within 2～3 weeks.Chronic diarrhea refer to the course of disease more than two months or the recurrent of intermission in 2～4 weeks suffer from diarrhoea.。
Summary of the invention
The purpose of this invention is to provide a kind of treatment diarrheal medicament.
In order to realize the object of the invention; The present invention provides a kind of treatment diarrheal medicament, and it is to be processed by following materials by weight: 2～6 parts of Rhizoma Cibotii 3-8 part, 4～8 parts of Pericarpium Citri Reticulataes, 3～6 parts of Semen Euryaless, 2～5 parts of Semen Plantaginiss, 3～6 parts of Herba Taraxacis, 1～10 part of Radix Bupleuri, 3～6 parts of Radix Puerariaes, 2～6 parts of Rhizoma Chuanxiongs, 1～4 part of Herba Houttuyniae, 3～7 parts in Radix Glycyrrhizae and Radix Paeoniae Rubra.
Preferably, treatment diarrheal powder of the present invention is to be processed by following materials by weight: 4 parts of 5 parts of Rhizoma Cibotiis, 6 parts of Pericarpium Citri Reticulataes, 5 parts of Semen Euryaless, 4 parts of Semen Plantaginiss, 4 parts of Herba Taraxacis, 5 parts of Radix Bupleuri, 6 parts of Radix Puerariaes, 4 parts of Rhizoma Chuanxiongs, 2 parts of Herba Houttuyniae, 6 parts in Radix Glycyrrhizae and Radix Paeoniae Rubra.
Preferably, said medicament can be processed tablet, dispersible tablet, powder or capsule.Can adopt method well known to those skilled in the art to carry out preparation of medicaments.As required, can add various pharmaceutically acceptable carriers.Described carrier comprises the conventional diluent of pharmaceutical field, excipient, filler, binding agent, wetting agent, disintegrating agent, absorption enhancer, surfactant, absorption carrier, lubricant etc.Medicament of the present invention in the preparation, selectable filler has: starch, Icing Sugar, calcium phosphate, dextrin, microcrystalline Cellulose, lactose, pregelatinized Starch, mannitol etc.; Selectable binding agent has: sodium carboxymethyl cellulose, PVP-K30, hydroxypropyl cellulose, starch slurry, methylcellulose, ethyl cellulose, hydroxypropyl emthylcellulose, gelling starch etc.; Selectable disintegrating agent has: dried starch, polyvinylpolypyrrolidone, cross-linking sodium carboxymethyl cellulose, carboxymethyl starch sodium, low-substituted hydroxypropyl cellulose etc.; Selectable lubricant has: magnesium stearate, Pulvis Talci, sodium lauryl sulphate, micropowder silica gel etc.
Component of the present invention is simple, with low cost, and therapeutic effect is more satisfactory, for diarrhoea apparent in view therapeutic effect is arranged.
The specific embodiment
Further specify the present invention through embodiment below.It should be understood that embodiments of the invention are to be used to explain the present invention rather than limitation of the present invention.The simple modifications that essence according to the present invention is carried out the present invention all belongs to the present invention and requires the scope protected.
The preparation of embodiment 1 powder
Take by weighing Rhizoma Cibotii 50 grams, Pericarpium Citri Reticulatae 60 grams, Semen Euryales 50 grams, Semen Plantaginis 40 grams, Herba Taraxaci 40 grams, Radix Bupleuri 50 grams, Radix Puerariae 60 grams, Rhizoma Chuanxiong 40 grams, Herba Houttuyniae 20 grams, Radix Glycyrrhizae 60 grams and Radix Paeoniae Rubra 40 grams and fully mix, pulverize, cross 80 mesh sieves.Take by weighing Icing Sugar 250 grams then, cross 80 mesh sieves and above-mentioned raw materials and mix, promptly get.Gained powder is divided into 100 bags.
Experimental example
Diagnostic criteria
Confirm the diagnostic criteria of diarrhea patient according to " internal medicine " (the 2nd edition, the People's Health Publisher publishes): the patient stool is increased, and day reaches 3-5 time, and is very more.The stool color is yellowish, is rare water or egg soup sample.The patient with feel sick, vomiting and in various degree dehydration and electrolyte disturbance.Close patient's 40 examples of the standard of stating of selector, male's 20 examples wherein, women's 20 examples, 23 years old mean age.
Use the powder of the present invention of embodiment 1 preparation to treat, every day twice, each 1 bag, 4 days is a course of treatment.
Diagnostic criteria
Produce effects: defecate below 3 times every day in the medication 48h, and that its character is recovered is normal, clinical symptoms and sign disappear.Effectively: defecate below 3 times every day in the medication 96h, and other clinical symptoms and sign alleviate.Invalid: the character of defecating behind the medication 96h, clinical symptoms and sign change not obvious.
Through the treatment of a course of treatment, all the patient all meets the standard of produce effects.And in therapeutic process, do not see obvious adverse reaction.
Claims (3)
1. treat the diarrheal medicament for one kind; It is characterized in that it is to be processed by following materials by weight: 2～6 parts of Rhizoma Cibotii 3-8 part, 4～8 parts of Pericarpium Citri Reticulataes, 3～6 parts of Semen Euryaless, 2～5 parts of Semen Plantaginiss, 3～6 parts of Herba Taraxacis, 1～10 part of Radix Bupleuri, 3～6 parts of Radix Puerariaes, 2～6 parts of Rhizoma Chuanxiongs, 1～4 part of Herba Houttuyniae, 3～7 parts in Radix Glycyrrhizae and Radix Paeoniae Rubra.
2. treatment diarrheal medicament according to claim 1; It is characterized in that it is to be processed by following materials by weight: 4 parts of 5 parts of Rhizoma Cibotiis, 6 parts of Pericarpium Citri Reticulataes, 5 parts of Semen Euryaless, 4 parts of Semen Plantaginiss, 4 parts of Herba Taraxacis, 5 parts of Radix Bupleuri, 6 parts of Radix Puerariaes, 4 parts of Rhizoma Chuanxiongs, 2 parts of Herba Houttuyniae, 6 parts in Radix Glycyrrhizae and Radix Paeoniae Rubra.
3. treatment diarrheal medicament according to claim 1 and 2 is characterized in that said medicament can be processed tablet, dispersible tablet, powder or capsule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210078812 CN102552511B (en) | 2012-03-23 | 2012-03-23 | Medicament for treating diarrhea |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210078812 CN102552511B (en) | 2012-03-23 | 2012-03-23 | Medicament for treating diarrhea |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102552511A true CN102552511A (en) | 2012-07-11 |
| CN102552511B CN102552511B (en) | 2013-08-07 |
Family
ID=46399966
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201210078812 Active CN102552511B (en) | 2012-03-23 | 2012-03-23 | Medicament for treating diarrhea |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102552511B (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103157090A (en) * | 2013-03-22 | 2013-06-19 | 杨雪珍 | Medicament for treating diarrhea |
| CN103566241A (en) * | 2013-11-05 | 2014-02-12 | 安徽工贸职业技术学院 | Traditional Chinese medicinal composition for treating diarrhea |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1430999A (en) * | 2003-01-28 | 2003-07-23 | 南京师范大学 | Chinese herbal medicine combination for treating disease of disorder of bowels's function and its product |
| JP2009215276A (en) * | 2008-02-12 | 2009-09-24 | Fujifilm Corp | Oral administration composition containing plant belonging to genus salacia |
| KR20110125318A (en) * | 2010-05-13 | 2011-11-21 | 주식회사 대산 | Antibiotic composition comprising plants extract mixture |
| CN102370926A (en) * | 2010-08-20 | 2012-03-14 | 高英豪 | Chinese medicament for treating acute enteritis |
-
2012
- 2012-03-23 CN CN 201210078812 patent/CN102552511B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1430999A (en) * | 2003-01-28 | 2003-07-23 | 南京师范大学 | Chinese herbal medicine combination for treating disease of disorder of bowels's function and its product |
| JP2009215276A (en) * | 2008-02-12 | 2009-09-24 | Fujifilm Corp | Oral administration composition containing plant belonging to genus salacia |
| KR20110125318A (en) * | 2010-05-13 | 2011-11-21 | 주식회사 대산 | Antibiotic composition comprising plants extract mixture |
| CN102370926A (en) * | 2010-08-20 | 2012-03-14 | 高英豪 | Chinese medicament for treating acute enteritis |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103157090A (en) * | 2013-03-22 | 2013-06-19 | 杨雪珍 | Medicament for treating diarrhea |
| CN103566241A (en) * | 2013-11-05 | 2014-02-12 | 安徽工贸职业技术学院 | Traditional Chinese medicinal composition for treating diarrhea |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102552511B (en) | 2013-08-07 |
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Owner name: LIYANG SHANGHUANG HOSPITALS Free format text: FORMER OWNER: LIU JIE Effective date: 20131122 |
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Free format text: CORRECT: ADDRESS; FROM: 272100 JINING, SHANDONG PROVINCE TO: 213314 CHANGZHOU, JIANGSU PROVINCE |
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Effective date of registration: 20131122 Address after: 213314, Huang Zhen Town, Liyang, Jiangsu, Changzhou Patentee after: Liyang Huang Zhen Town Health Center Address before: 272100 Department of Gastroenterology, the first people's Hospital of Jining, 6 health Road, Shandong City, Jining Province, China Patentee before: Liu Jie |