CN105288565A - Traditional Chinese medicine composition for treating rheumatoid bone diseases - Google Patents
Traditional Chinese medicine composition for treating rheumatoid bone diseases Download PDFInfo
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- CN105288565A CN105288565A CN201510859126.9A CN201510859126A CN105288565A CN 105288565 A CN105288565 A CN 105288565A CN 201510859126 A CN201510859126 A CN 201510859126A CN 105288565 A CN105288565 A CN 105288565A
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Abstract
The invention relates to a traditional Chinese medicine composition for treating rheumatoid bone diseases. The composition is prepared from corn cervipantotrichum, the bark of eucommia, radix flemingiaes, panaxnotoginseng, ground beeltles, radix ginseng rubra, geranium wilfordiimaxim, human placenta, phrymaleptostachya, ganodermalucidum, ligusticum chuanxiong hort, dragon's blood, angelica sinensis, polygonatum sibiricum, the root of three-nerved spicebush, floscarthami, fructuskochiae, semen cassiae, dried radix rehmanniae, processed radix aconitilateralis, dried ginger, puerarin, towel gourd vegetable sponge, carapaxtrionycis, achyranthesbidentata and morning glory. The traditional Chinese medicine composition is good in synergistic effect, and while can quickly and effectively treat rheumatoid bone diseases, the relapse is not easy. A compound sustained-release capsule resolves the current problems and eliminates the root causes, while can quickly relieve swelling and pain, arthritis is radically cured, the human body functions can be adjusted, antibody formation is promoted, the immunity is improved, the capsule is conducive to the recovery of rheumatic arthritis, and the relapse is avoided.
Description
Technical field
The present invention relates to field of medicaments, relate in particular to a kind of Chinese medicine composition for the treatment of rheumatic osteopathia.
Background technology
Rheumatic arthritis belongs to allergic disease, it is one of main manifestations of rheumatic fever, mainly with febris acuta and arthralgia onset, typical performance is slight or moderate heating, migratory polyarthritis, affected joints mostly is knee joint, ankle, shoulder, elbow, the large joint such as wrist, commonly be transferred to another joint by a joint, pathological changes local presents red, swollen, scorching hot, severe pain, some patients also has several joint to fall ill simultaneously, atypical patient only has arthralgia and without other struvite performances, acute inflammation generally disappeared in 2 ~ 4 weeks, do not stay sequela, but normal recurrent exerbation.If active rheumatism affects heart, then can there is myocarditis, even leave over valve disorder.Common sympton is anemofrigid-damp arthralgia arthralgia, joint aches, the gonalgia, arthroncus, ankylosis, heating companion arthralgia, joint fluid ooze out, limbs or trunk numb.Rheumatic arthritis onset is more anxious, affected joints is based on large joint, start to invade and joint of the lower extremity person accounts for 85%, knee joint and ankle joint are the most common, are secondly shoulder, elbow and wrist, the Minor articulus of hands and foot is rare, can to occur together heat in arthritis patients during acute stage, pharyngalgia, nervous, erythrocyte sedimentation rate speed and C reactive protein such as to increase at the performance, can return to normal after sb.'s illness took a favorable turn.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine composition for the treatment of rheumatic osteopathia.
In order to realize object of the present invention, the invention provides a kind of Chinese medicine composition for the treatment of rheumatic osteopathia, it comprises the material of following weight portion: Cornu Cervi Pantotrichum 5-15 part, Cortex Eucommiae 9-15 part, Radix Flemingiae Philippinensis 10-30 part, Radix Notoginseng 5-15 part, Eupolyphaga Seu Steleophaga 10-15 part, Radix Ginseng Rubra 10-25 part, Herba Erodii 15-30 part, Placenta Hominis 10-25 part, Herba speranskiae tuberculatae 15-30 part, Ganoderma 10-15 part, Rhizoma Chuanxiong 10-20 part, Sanguis Draxonis 3-9 part, Radix Angelicae Sinensis 15-30 part, Rhizoma Polygonati 30-60 part, Radix Linderae 15-30 part, Flos Carthami 5-10 part, Fructus Kochiae 10-18 part, Semen Cassiae 5-15 part, Radix Rehmanniae 15-30 part, Radix Aconiti Lateralis Preparata 30-60 part, Rhizoma Zingiberis 5-10 part, Radix Puerariae 15-30 part, Retinervus Luffae Fructus 10-15 part, Carapax Trionycis 6-15 part, Radix Achyranthis Bidentatae 9-20 part and Semen Pharbitidis 5-10 part.
Preferably, the Chinese medicine composition for the treatment of rheumatic osteopathia of the present invention comprises the material of following weight portion: 10 parts, Cornu Cervi Pantotrichum, the Cortex Eucommiae 12 parts, Radix Flemingiae Philippinensis 20 parts, Radix Notoginseng 10 parts, Eupolyphaga Seu Steleophaga 12 parts, Radix Ginseng Rubra 20 parts, Herba Erodii 25 parts, Placenta Hominis 15 parts, Herba speranskiae tuberculatae 20 parts, Ganoderma 12 parts, Rhizoma Chuanxiong 15 parts, Sanguis Draxonis 5 parts, Radix Angelicae Sinensis 20 parts, Rhizoma Polygonati 40 parts, the Radix Linderae 20 parts, 8 parts, Flos Carthami, the Fructus Kochiae 15 parts, Semen Cassiae 10 parts, 20 parts, the Radix Rehmanniae, Radix Aconiti Lateralis Preparata 50 parts, Rhizoma Zingiberis 8 parts, Radix Puerariae 20 parts, Retinervus Luffae Fructus 12 parts, Carapax Trionycis 10 parts, Radix Achyranthis Bidentatae 15 parts and Semen Pharbitidis 8 parts.
More preferably, the Chinese medicine composition for the treatment of rheumatic osteopathia of the present invention also comprises the material of following weight portion: 2-(3,4,5-trimethoxy) benzoyl-5-(the 4-Liquid Crystal Compounds Intermediate p-Ethyl-phenylacetylene base) thiophene of 0.05 part.
Most preferably, described Chinese medicine composition can be tablet, dispersible tablet, capsule, pill or decoction.
The present invention also provides the purposes of 2-(3,4,5-trimethoxy) benzoyl-5-(4-Liquid Crystal Compounds Intermediate p-Ethyl-phenylacetylene base) thiophene in the medicine of preparation treatment rheumatic osteopathia, rheumatism antiinflammatory.
Chinese medicine composition synergistic action effect of the present invention is good, can be not easy recurrence while rapid, effective treatment rheumatic arthritis.This compound sustained release capsules treating both the principal and secondary aspects of a disease, can radical cure arthritis while reducing swelling and alleviating pain fast, and human body function enhancing antibody can be regulated to be formed, improve body immunity, the rehabilitation contributing to rheumatic arthritis is avoided recurring.
Detailed description of the invention
The present invention is further illustrated below by embodiment.It should be understood that embodiments of the invention are for illustration of the present invention instead of limitation of the present invention.Essence according to the present invention all belongs to the scope of protection of present invention to the simple modifications that the present invention carries out.Unless otherwise stated, the percent in the present invention is percetage by weight.
Embodiment
Take 10 grams, Cornu Cervi Pantotrichum, the Cortex Eucommiae 12 grams, Radix Flemingiae Philippinensis 20 grams, Radix Notoginseng 10 grams, Eupolyphaga Seu Steleophaga 12 grams, Radix Ginseng Rubra 20 grams, Herba Erodii 25 grams, Placenta Hominis 15 grams, Herba speranskiae tuberculatae 20 grams, Ganoderma 12 grams, Rhizoma Chuanxiong 15 grams, Sanguis Draxonis 5 grams, Radix Angelicae Sinensis 20 grams, Rhizoma Polygonati 40 grams, the Radix Linderae 20 grams, 8 grams, Flos Carthami, the Fructus Kochiae 15 grams, Semen Cassiae 10 grams, 20 grams, the Radix Rehmanniae, Radix Aconiti Lateralis Preparata 50 grams, Rhizoma Zingiberis 8 grams, Radix Puerariae 20 grams, Retinervus Luffae Fructus 12 grams, Carapax Trionycis 10 grams, Radix Achyranthis Bidentatae 15 grams and Semen Pharbitidis 8 grams, pulverize, cross 100 mesh sieves, mix homogeneously obtains powder.
Experimental example
On the impact of mice auricle swelling
Get the healthy Kunming mouse 50 of body weight 18-22g, male and female half and half, are divided into 5 groups at random: matched group, positive drug group, administration group 1, administration group 2, administration group 3.Often organize 10.Matched group gives normal saline gavage 1mL/1000g body weight; Positive drug group gives dexamethasone 0.5g and adds 1000mL normal saline and become suspension to give gavage 1mL/1000g body weight; Administration group 1, the powder 10g of embodiment adds 1000mL normal saline and becomes suspension, gives gavage 1mL/1000g body weight; 2-(3,4,5-trimethoxy) benzoyl-5-(the 4-Liquid Crystal Compounds Intermediate p-Ethyl-phenylacetylene base) thiophene of administration group 2,0.02g adds 1000mL normal saline and becomes suspension, gives gavage 1mL/1000g body weight; Administration group 3,2-(3,4,5-trimethoxy) benzoyl-5-(the 4-Liquid Crystal Compounds Intermediate p-Ethyl-phenylacetylene base) thiophene of powder 5g and 0.01g of embodiment adds 1000mL normal saline and becomes suspension, gives gavage 1mL/1000g body weight.1 times/day, successive administration 7 days.After last administration 30min, only every left auricle of mice is coated with equably dimethylbenzene 0.05ml/, after causing scorching 15min, mice is taken off cervical vertebra to put to death, with the card punch of diameter 6.5mm, ears are cut with position, weigh on electronic balance respectively, with the difference of left and right auricle weight for swelling, calculate each group of swelling rate, adopt t to check more each administration group and matched group difference condition.The results are shown in following table.(n=10
)
Group | Two auricle differences (mg) | Swelling rate (%) |
Matched group | 16.8±4.1 | 122.15±23.8 |
Positive drug group | 11.3±2.9 | 80.26±16.7* |
Administration group 1 | 15.1±4.3 | 98.25±9.9* |
Administration group 2 | 12.6±3.2 | 83.61±13.3* |
Administration group 3 | 13.8±3.5 | 90.05±10.2* |
Note: compare * P < 0.05 with matched group
Result shows, compares with matched group, and medicine of the present invention all can suppress the mice auricle swelling (p < 0.05) caused by dimethylbenzene, and stronger antiinflammatory action is described.
Claims (5)
1. treat the Chinese medicine composition of rheumatic osteopathia for one kind, it is characterized in that, it comprises the material of following weight portion: Cornu Cervi Pantotrichum 5-15 part, Cortex Eucommiae 9-15 part, Radix Flemingiae Philippinensis 10-30 part, Radix Notoginseng 5-15 part, Eupolyphaga Seu Steleophaga 10-15 part, Radix Ginseng Rubra 10-25 part, Herba Erodii 15-30 part, Placenta Hominis 10-25 part, Herba speranskiae tuberculatae 15-30 part, Ganoderma 10-15 part, Rhizoma Chuanxiong 10-20 part, Sanguis Draxonis 3-9 part, Radix Angelicae Sinensis 15-30 part, Rhizoma Polygonati 30-60 part, Radix Linderae 15-30 part, Flos Carthami 5-10 part, Fructus Kochiae 10-18 part, Semen Cassiae 5-15 part, Radix Rehmanniae 15-30 part, Radix Aconiti Lateralis Preparata 30-60 part, Rhizoma Zingiberis 5-10 part, Radix Puerariae 15-30 part, Retinervus Luffae Fructus 10-15 part, Carapax Trionycis 6-15 part, Radix Achyranthis Bidentatae 9-20 part and Semen Pharbitidis 5-10 part.
2. the Chinese medicine composition for the treatment of rheumatic osteopathia according to claim 1, it is characterized in that, it comprises the material of following weight portion: 10 parts, Cornu Cervi Pantotrichum, the Cortex Eucommiae 12 parts, Radix Flemingiae Philippinensis 20 parts, Radix Notoginseng 10 parts, Eupolyphaga Seu Steleophaga 12 parts, Radix Ginseng Rubra 20 parts, Herba Erodii 25 parts, Placenta Hominis 15 parts, Herba speranskiae tuberculatae 20 parts, Ganoderma 12 parts, Rhizoma Chuanxiong 15 parts, Sanguis Draxonis 5 parts, Radix Angelicae Sinensis 20 parts, Rhizoma Polygonati 40 parts, the Radix Linderae 20 parts, 8 parts, Flos Carthami, the Fructus Kochiae 15 parts, Semen Cassiae 10 parts, 20 parts, the Radix Rehmanniae, Radix Aconiti Lateralis Preparata 50 parts, Rhizoma Zingiberis 8 parts, Radix Puerariae 20 parts, Retinervus Luffae Fructus 12 parts, Carapax Trionycis 10 parts, Radix Achyranthis Bidentatae 15 parts and Semen Pharbitidis 8 parts.
3. the Chinese medicine composition for the treatment of rheumatic osteopathia according to claim 1 and 2; it is characterized in that; it also comprises the material of following weight portion: 2-(3,4,5-trimethoxy) benzoyl-5-(the 4-Liquid Crystal Compounds Intermediate p-Ethyl-phenylacetylene base) thiophene of 0.05 part.
4. the Chinese medicine composition for the treatment of rheumatic osteopathia according to claim 1 and 2, is characterized in that, described Chinese medicine composition can be tablet, dispersible tablet, capsule, pill or decoction.
The purposes of 5.2-(3,4,5-trimethoxy) benzoyl-5-(4-Liquid Crystal Compounds Intermediate p-Ethyl-phenylacetylene base) thiophene in the medicine of preparation treatment rheumatic osteopathia.
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105853737A (en) * | 2016-05-17 | 2016-08-17 | 范信 | Medicine for treating rheumatism and neck shoulder backleg pain |
CN106214892A (en) * | 2016-08-31 | 2016-12-14 | 李民功 | A kind of Chinese medicine treating osteoarthritis |
CN106390131A (en) * | 2016-11-30 | 2017-02-15 | 郑州仁宏医药科技有限公司 | Western medicine composition for treating rheumatic bone disease |
CN106389884A (en) * | 2016-10-21 | 2017-02-15 | 代立新 | Traditional Chinese medicine for treating rheumatic bone disease and preparation method |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN103251760A (en) * | 2013-03-01 | 2013-08-21 | 溧阳市天目湖保健品有限公司 | Traditional Chinese medicinal composition for treating rheumatism |
CN103263659A (en) * | 2013-06-17 | 2013-08-28 | 崔新明 | Traditional Chinese medicine composition for treating rheumatism bone diseases |
-
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- 2015-11-30 CN CN201510859126.9A patent/CN105288565A/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103251760A (en) * | 2013-03-01 | 2013-08-21 | 溧阳市天目湖保健品有限公司 | Traditional Chinese medicinal composition for treating rheumatism |
CN103263659A (en) * | 2013-06-17 | 2013-08-28 | 崔新明 | Traditional Chinese medicine composition for treating rheumatism bone diseases |
Non-Patent Citations (1)
Title |
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周萍: "《中医学概论》", 31 January 2003, 安徽科学技术出版社 * |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105853737A (en) * | 2016-05-17 | 2016-08-17 | 范信 | Medicine for treating rheumatism and neck shoulder backleg pain |
CN106214892A (en) * | 2016-08-31 | 2016-12-14 | 李民功 | A kind of Chinese medicine treating osteoarthritis |
CN106389884A (en) * | 2016-10-21 | 2017-02-15 | 代立新 | Traditional Chinese medicine for treating rheumatic bone disease and preparation method |
CN106390131A (en) * | 2016-11-30 | 2017-02-15 | 郑州仁宏医药科技有限公司 | Western medicine composition for treating rheumatic bone disease |
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