CN106511584A - Drug for treating postpartum fever - Google Patents

Drug for treating postpartum fever Download PDF

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Publication number
CN106511584A
CN106511584A CN201611069678.0A CN201611069678A CN106511584A CN 106511584 A CN106511584 A CN 106511584A CN 201611069678 A CN201611069678 A CN 201611069678A CN 106511584 A CN106511584 A CN 106511584A
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parts
radix
medicine
raw material
angelicae sinensis
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黄俊源
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/35—Caprifoliaceae (Honeysuckle family)
    • A61K36/355—Lonicera (honeysuckle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236—Ligusticum (licorice-root)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287—Chrysanthemum, e.g. daisy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288—Taraxacum (dandelion)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634—Forsythia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708—Rheum (rhubarb)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/78—Saururaceae (Lizard's-tail family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
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  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
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  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention provides a drug for treating postpartum fever. The drug is prepared from the following raw materials in parts by weight: 10-20 parts of lonicera japonica, 10-20 parts of herba taraxaci, 10-20 parts of flos chrysanthemi indici, 5-15 parts of rhizome chuanxiong, 10-30 parts of radix angelicae sinensis, 5-10 parts of peach seeds, 5-10 parts of radix paeoniae rubra, 5-10 parts of fructus aurantii, 5-10 parts of radix glycyrrhizae preparata, 5-10 parts of rhubarb, 10-20 parts of fructus forsythia and 10-20 parts of herba houttuyniae. The drug for treating the postpartum fever is cheap and good in treatment effect and has few toxic and side effects.

Description

The medicine for the treatment of puerperal fever
Technical field
The present invention relates to a kind of medicine for treating puerperal fever, belongs to technical field of Chinese medicines.
Background technology
Puerperal fever, be in term, puerpera's hyperpyrexia shiver with cold or generate heat it is persistent, and with causes such as other symptoms, Which is one of obstetric condition, because the wound surface of reproductive tract is by infecting for causing a disease, causes inflammatory activity locally or systemically, and severe patient can Cause septicemia, toxic shock, while renal dysfunction, jeopardizes puerpera's life.People only make to disappear with general Western medicine at ordinary times Hot always rare healing, and the expensive acceptance that mustn't go to patient.
The content of the invention
The technical problem to be solved in the present invention：There is provided the treatment that a kind of low price, therapeutic effect are good, have no toxic side effect to produce The medicine for generating heat afterwards.
To solve above-mentioned technical problem, the present invention is employed the following technical solutions：
The medicine for the treatment of puerperal fever, is obtained by the raw material of following weight parts：Flos Lonicerae 10-20 parts, Herba Taraxaci 10-20 Part, Flos Chrysanthemi Indici 10-20 parts, Rhizoma Chuanxiong 5-15 parts, Radix Angelicae Sinensis 10-30 parts, Semen Persicae 5-10 parts, also Radix Paeoniae 5-10 parts, Fructus Aurantii 5-10 parts, process Radix Glycyrrhizae 5-10 parts, Radix Et Rhizoma Rhei 5-10 parts, Fructus Forsythiae 10-20 parts, Herba Houttuyniae 10-20 parts.
As preferred, a specific formula is provided here, the weight portion of the raw material is：10 parts of Flos Lonicerae, Pu Gong 10 parts of English, 10 parts of Flos Chrysanthemi Indici, 5 parts of Rhizoma Chuanxiong, 10 parts of Radix Angelicae Sinensis, also 5 parts of Semen Persicae, 5 parts of Radix Paeoniae, 5 parts of Fructus Aurantii, 5 parts of Radix Glycyrrhizae Preparata, Radix Et Rhizoma Rhei 5 Part, 10 parts of Fructus Forsythiae, 10 parts of Herba Houttuyniae.
As preferred, two specific formula are provided here, the weight portion of the raw material is：20 parts of Flos Lonicerae, Pu Gong 20 parts of English, 20 parts of Flos Chrysanthemi Indici, 15 parts of Rhizoma Chuanxiong, 30 parts of Radix Angelicae Sinensis, 10 parts of Semen Persicae, also 10 parts of Radix Paeoniae, 10 parts of Fructus Aurantii, 10 parts of Radix Glycyrrhizae Preparata, 10 parts of Radix Et Rhizoma Rhei, 20 parts of Fructus Forsythiae, 20 parts of Herba Houttuyniae.
As preferred, three specific formula are provided here, the weight portion of the raw material is：15 parts of Flos Lonicerae, Pu Gong 15 parts of English, 15 parts of Flos Chrysanthemi Indici, 10 parts of Rhizoma Chuanxiong, 20 parts of Radix Angelicae Sinensis, also 8 parts of Semen Persicae, 8 parts of Radix Paeoniae, 8 parts of Fructus Aurantii, 8 parts of Radix Glycyrrhizae Preparata, Radix Et Rhizoma Rhei 8 Part, 15 parts of Fructus Forsythiae, 15 parts of Herba Houttuyniae.
The present invention also provides above-mentioned technical method, and which the following is suddenly：The raw material for possessing is put in marmite and is added suitably Ask water, can obtain the medicine with being cooked by slow fire 10 minutes.
The using method of the medicine is：400-500 milliliters are each taken, 3 times is taken within one day.
The invention has the beneficial effects as follows：The raw material of the present invention is often Chinese herbal medicine, wide material sources, low price；Pharmaceutical formulation Scientific and reasonable, synergism between each component can heat-clearing and toxic substances removing, regulating qi-flowing for activating stagnancy, blood stasis dispelling, the work(only suffered from abdominal pain, can remove fever with chills Energy.
Specific embodiment
The present invention is further illustrated by the following examples, but the invention is not restricted to these embodiments.
Embodiment 1
The medicine for the treatment of puerperal fever, is obtained by the raw material of following weight parts：10 parts of Flos Lonicerae, 10 parts of Herba Taraxaci, Herba Dendranthematis indici Spend 10 parts, 5 parts of Rhizoma Chuanxiong, 10 parts of Radix Angelicae Sinensis, 5 parts of Semen Persicae, also 5 parts of Radix Paeoniae, 5 parts of Fructus Aurantii, 5 parts of Radix Glycyrrhizae Preparata, 5 parts of Radix Et Rhizoma Rhei, 10 parts of Fructus Forsythiae, 10 parts of Herba Houttuyniae.
The preparation method of medicine is：The raw material for possessing is put in marmite add it is appropriate ask water, with being cooked by slow fire 10 Minute can obtain the medicine.
Embodiment 2
The medicine for the treatment of puerperal fever, is obtained by the raw material of following weight parts：20 parts of Flos Lonicerae, 20 parts of Herba Taraxaci, Herba Dendranthematis indici Spend 20 parts, 15 parts of Rhizoma Chuanxiong, 30 parts of Radix Angelicae Sinensis, 10 parts of Semen Persicae, also 10 parts of Radix Paeoniae, 10 parts of Fructus Aurantii, 10 parts of Radix Glycyrrhizae Preparata, 10 parts of Radix Et Rhizoma Rhei, even Stick up 20 parts, 20 parts of Herba Houttuyniae.
The preparation method of medicine is：The raw material for possessing is put in marmite add it is appropriate ask water, with being cooked by slow fire 10 Minute can obtain the medicine.
Embodiment 3
The medicine for the treatment of puerperal fever, is obtained by the raw material of following weight parts：15 parts of Flos Lonicerae, 15 parts of Herba Taraxaci, Herba Dendranthematis indici Spend 15 parts, 10 parts of Rhizoma Chuanxiong, 20 parts of Radix Angelicae Sinensis, 8 parts of Semen Persicae, also 8 parts of Radix Paeoniae, 8 parts of Fructus Aurantii, 8 parts of Radix Glycyrrhizae Preparata, 8 parts of Radix Et Rhizoma Rhei, Fructus Forsythiae 15 Part, 15 parts of Herba Houttuyniae.
The preparation method of medicine is：The raw material for possessing is put in marmite add it is appropriate ask water, with being cooked by slow fire 10 Minute can obtain the medicine.
Toxicity formula is tested
Medicine during test drug in the embodiment of the present invention 1.Experimental animal is ICR kind white mice, and body weight 20-25 gram is female Male half and half, totally 40 test method(s)s are, after fasting 15 hours, to give mice lavage 4 months, long term toxicity test by daily 20 milliliters As a result show that white mice body weight, liver function, renal function, hemogram etc. and matched group no significant difference show the safety of the medicine Greatly, belong to nontoxic rank.
Therapeutic effect
Proof test, average cure rate are carried out to 140 women for respectively suffering from puerperal fever using medicine obtained in embodiment 1 Up to 85%.Wherein：All fully recover in 10 people less than 18 years old；28 people recovery from illness in the people of 18-20 year, wherein 1 people is because taking other It is invalid that medicine is discontinued；27 people recovery from illness in 30 people of 20-25 year, wherein 2 people are invalid because taking other drugs；30 people of 25-30 year In 25 people recovery from illness, wherein 1 people because take other drugs drug withdrawal it is invalid；23 people recovery from illness in 30 people of 30-35 year, wherein 3 people are because of clothes It is discontinued with other drugs；In 10 people of more than 35 years old, 6 people fully recover from an illness, wherein 1 people is discontinued because taking other drugs.

Claims (5)

1. the medicine of puerperal fever is treated, it is characterised in that be obtained by the raw material of following weight parts：Flos Lonicerae 10-20 parts, Pu Gong English 10-20 parts, Flos Chrysanthemi Indici 10-20 parts, Rhizoma Chuanxiong 5-15 parts, Radix Angelicae Sinensis 10-30 parts, also Semen Persicae 5-10 parts, Radix Paeoniae 5-10 parts, Fructus Aurantii 5-10 parts, Radix Glycyrrhizae Preparata 5-10 parts, Radix Et Rhizoma Rhei 5-10 parts, Fructus Forsythiae 10-20 parts, Herba Houttuyniae 10-20 parts.
2. medicine according to claim 1, it is characterised in that the weight portion of the raw material is：10 parts of Flos Lonicerae, Herba Taraxaci 10 parts, 10 parts of Flos Chrysanthemi Indici, 5 parts of Rhizoma Chuanxiong, 10 parts of Radix Angelicae Sinensis, 5 parts of Semen Persicae, also 5 parts of Radix Paeoniae, 5 parts of Fructus Aurantii, 5 parts of Radix Glycyrrhizae Preparata, 5 parts of Radix Et Rhizoma Rhei, 10 parts of Fructus Forsythiae, 10 parts of Herba Houttuyniae.
3. medicine according to claim 1, it is characterised in that the weight portion of the raw material is：20 parts of Flos Lonicerae, Herba Taraxaci 20 parts, 20 parts of Flos Chrysanthemi Indici, 15 parts of Rhizoma Chuanxiong, 30 parts of Radix Angelicae Sinensis, 10 parts of Semen Persicae, also 10 parts of Radix Paeoniae, 10 parts of Fructus Aurantii, 10 parts of Radix Glycyrrhizae Preparata, big Yellow 10 parts, 20 parts of Fructus Forsythiae, 20 parts of Herba Houttuyniae.
4. medicine according to claim 1, it is characterised in that the weight portion of the raw material is：15 parts of Flos Lonicerae, Herba Taraxaci 15 parts, 15 parts of Flos Chrysanthemi Indici, 10 parts of Rhizoma Chuanxiong, 20 parts of Radix Angelicae Sinensis, 8 parts of Semen Persicae, also 8 parts of Radix Paeoniae, 8 parts of Fructus Aurantii, 8 parts of Radix Glycyrrhizae Preparata, Radix Et Rhizoma Rhei 8 Part, 15 parts of Fructus Forsythiae, 15 parts of Herba Houttuyniae.
5. the medicine according to any one of claim 1-4, it is characterised in that the preparation method of medicine will be possessed Raw material be put in marmite add it is appropriate ask water, can obtain the medicine with being cooked by slow fire 10 minutes.
CN201611069678.0A 2016-11-16 2016-11-16 Drug for treating postpartum fever Pending CN106511584A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106389926A (en) * 2016-11-16 2017-02-15 黄俊源 Medicine for treating kidney deficiency and yin deficiency
CN108498638A (en) * 2017-11-21 2018-09-07 张祖玲 A kind of Chinese medicine and its preparation method and application for treating post gynecologic operation low fever

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102085302A (en) * 2009-12-04 2011-06-08 赵廷壁 Traditional Chinese medicine composition for treating puerperal fever

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102085302A (en) * 2009-12-04 2011-06-08 赵廷壁 Traditional Chinese medicine composition for treating puerperal fever

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
肇丽群: "产褥感染的诊治", 《中国实用乡村医生杂志》 *
赵艳玲等: "《国家标准中医临床诊疗术语 证治要览》", 30 April 1999 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106389926A (en) * 2016-11-16 2017-02-15 黄俊源 Medicine for treating kidney deficiency and yin deficiency
CN108498638A (en) * 2017-11-21 2018-09-07 张祖玲 A kind of Chinese medicine and its preparation method and application for treating post gynecologic operation low fever

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