CN103919874A - Traditional Chinese medicine powder for treating dental ulcer - Google Patents
Traditional Chinese medicine powder for treating dental ulcer Download PDFInfo
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- CN103919874A CN103919874A CN201410150212.8A CN201410150212A CN103919874A CN 103919874 A CN103919874 A CN 103919874A CN 201410150212 A CN201410150212 A CN 201410150212A CN 103919874 A CN103919874 A CN 103919874A
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- radix
- alumen
- borneolum syntheticum
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- indigo naturalis
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Abstract
The invention discloses a traditional Chinese medicine powder for treating dental ulcer, aims at solving the problems of poor effects in stopping pain, astringing wound surface and diminishing inflammation and swelling of an existing medicament for treating dental ulcer. The traditional Chinese medicine powder comprises the basic raw materials as follows: borneol, indigo naturalis, alum, pseudo-ginseng, astragalus root, honeysuckle, radix isatidis, liquorice, mint and coptis chinensis. The powder has a good effect of treating dental ulcer and stomatitis, is quick in wound astringency, capable of quickly diminishing inflammation and swelling, short in treatment time, capable of stopping pain after application of the powder once or twice, and high in effective rate up to over 98%.
Description
Invention field
The present invention relates to a kind of Chinese powder medicine, be specifically related to a kind of Chinese powder medicine that is used for the treatment of oral ulcer.
Background of invention
Recurrent oral ulceration is modal disease in diseases of oral mucosa.Prevalence occupies the first place of diseases of oral mucosa.Sircus (1975) investigates 1587 people, and prevalence is 20%; 9463 people investigate in Stomatological Hospital of Beijing Medical Univ., and prevalence is 18.3%.As can be seen here, oral ulcer patient is a very huge colony.The cause of disease complexity of recurrent oral ulceration, still indefinite so far, may be relevant with the factor such as endocrine regulation, immune dysfunction of viral infection, antibacterial infection and body.
Herpetic oral ulcer is the oral ulcer being caused by herpesvirus, and common is herpes simplex oral ulcer, though common not as recurrent ulcer, be also a common type of oral ulcer.
The primary treatment measure of oral ulcer comprises topical therapeutic and whole body therapeutic, because topical therapeutic toxic and side effects is lower, has therefore obtained people's accreditation.Borax, the Alumen that topical therapeutic uses, the oral cavity ulcer powder of Borneolum Syntheticum, although listed in Ministry of Public Health standard (WS3-B-0017-89), be used for the treatment of recurrent oral ulceration, herpetic oral ulcer, determined curative effect, but due to reasons such as its mouthfeel, use and local irritations, patient's compliance is poor, is not therefore really used widely.
At present, the medicine for the treatment of oral ulcer, stomatitis mainly contains BINGPENG SAN, watermelon crystal, KOUKUILING.Above-mentioned all medicines, through numerous patients' clinical treatment, are that the effect of pain relieving, convergence wound surface, antiinflammatory, detumescence is all unsatisfactory, particularly exist the shortcoming of medication repeatedly, course of disease length.
Summary of the invention
The present invention will solve the undesirable problem of effect of pain relieving that the medicine of existing treatment oral ulcer, stomatitis exists, convergence wound surface, antiinflammatory, detumescence, provide a kind of good analgesic effect, wound surface convergence fast, anti-inflammation detumescence fast, treatment time short treatment oral ulcer, the Chinese powder medicine of stomatitis.
On the one hand, the present invention relates to a kind of Chinese powder medicine for the treatment of oral ulcer, wherein, raw material basic composition is:
Borneolum Syntheticum 2-10g Indigo Naturalis 2-5g Alumen 2-5g Radix Notoginseng 1-5g Radix Astragali 2-6g gold
Flos Lonicerae 3-6g Radix Isatidis 2-8g Radix Glycyrrhizae 1-5g Herba Menthae 1-3g Rhizoma Coptidis 1-3g.
Some embodiments therein, the Chinese powder medicine for the treatment of oral ulcer of the present invention, wherein, raw material basic composition is:
Borneolum Syntheticum 8g Indigo Naturalis 2.5g Alumen 2.5g Radix Notoginseng 3g Radix Astragali 2g Flos Lonicerae 5g
Radix Isatidis 4g Radix Glycyrrhizae 1.5g Herba Menthae 1g Rhizoma Coptidis 1g
In other embodiments, the Chinese powder medicine for the treatment of oral ulcer of the present invention, wherein, raw material basic composition is:
Borneolum Syntheticum 10g Indigo Naturalis 2g Alumen 2g Radix Notoginseng 2g Radix Astragali 3g Flos Lonicerae 6g
Radix Isatidis 5g Radix Glycyrrhizae 1g
Herba Menthae 1g Rhizoma Coptidis 1g.
In other embodiments, the Chinese powder medicine for the treatment of oral ulcer of the present invention, wherein, raw material basic composition is:
Borneolum Syntheticum 5g Indigo Naturalis 5g Alumen 5g Radix Notoginseng 2g Radix Astragali 6g Flos Lonicerae 3g Radix Isatidis 8g Radix Glycyrrhizae 5g Herba Menthae 1g Rhizoma Coptidis 3g.
On the other hand, the present invention relates to a kind of preparation method of Chinese powder medicine of the present invention, it comprises following steps:
Get Borneolum Syntheticum, Indigo Naturalis, Alumen and be milled to powder; Get after Radix Notoginseng, the Radix Astragali, Flos Lonicerae, Radix Isatidis, Radix Glycyrrhizae, Herba Menthae and Rhizoma Coptidis are pulverized and cross 200 mesh sieves, then mix with the Borneolum Syntheticum, Indigo Naturalis and the Alumen that grind composition, make powder, pack watering can (2 grams of doses) into.
In the present invention the herbal nature that uses as follows:
Borneolum Syntheticum: another name: Borneolum Syntheticum, Borneolum Syntheticum, brain, Borneolum Syntheticum, sheet brain, Borneolum Syntheticum brain, Flos Mume brain, natural Broneolum Syntheticum, old borneol, borneol.Main component is the crystallization obtaining in the resin of Borneolum Syntheticum and volatile oil, is to approach pure dextro Borneolum Syntheticum.Compendium of Material Medica: " treatment sore throat, headache, nose Xi, toothache, typhoid fever protrusion of the tongue, children's's pox fall into.Logical all keys, loose stagnated fire.
Indigo Naturalis: salty, cold.Heat-clearing and toxic substances removing, blood cooling and ecchymoses removing, purging liver-fire, arresting convulsion.For maculae caused by violent heat pathogen, heat in blood is told nosebleed, chest pain hemoptysis, aphtha, mumps, sore throat, pediatric epilepsy scared." book on Chinese herbal medicine covers bamboo fish trap ": eliminating pathogen in the liver, only spouting diarrhea, the postcibal vomiting phlegm-fire that disappears, drives epidemic disease headache, holds back also speckle of typhoid fever, and water is taken after mixing with liquid it.
Alumen: i.e. Potassium aluminum sulfate dodecahydrate, has bacteriostasis." Bencao Jingshu ": Alumen, sour in the mouth gas is cold and nontoxic, the dry anxious astringent therapy of its property, removing toxic substances heat extraction pendant is turbid.Lid cold and heat let out dysentery, all damp and hot doing, married woman Bai Wo, how by collapsing, thus puckery with anti-avulsion also.Erosion of the vulva malignant boil, the also wet fire of edge, ophthalmalgia is many by wind heat.Remove the hard tooth person of heat in the marrow admittedly, marrow is that heat is robbed sky, therefore and atrophic debility of bones tooth floats, and vitriol heat extraction to the marrow, therefore also lead it.Go polyp person in nose, the merit of sterilization heat extraction dampness also.Alumen, " herbal classic " main cold and heat are let out dysentery, and it is more than for a long time that this lid refers to let out dysentery, and collapse lingering diarrhea, because having a fever.Vitriol is excessively puckery, puckery with anti-avulsion, therefore can master.Vehement in case damp and hot side, stagnant just many, misuse astringent therapy, causes harm and differs, careful it.Married woman Bai Woduo is by collapsing, thus with astringent therapy with solid its mark, the controlling of eventually non-spys.Ophthalmalgia be can't help bulbar conjunctiva polyp and have external oculopathy, and also non-institute is suitable.Except solid heat in the marrow, only can provide its guiding, if call, it is private, counter damaging also.The dry urgency of vitriol, and can rob water, thus unfavorable dentary, therefore after tooth person bone also.
Radix Notoginseng: " detailed outline ": hemostasis, loose blood, analgesic therapy.Gold sword arrow wound, falls and flutters flogging injury, and blood goes out more than person, chews rotten painting, or for mixing it in end, its blood stop.Also main haematemesis, epistaxis, hematochezia, dysentery, metrorrhagia, incessant menorrhea, puerperal stagnant blood not under, blood fortune, blood pain, Akamu, carbuncle, tiger stings, all diseases of snakebite.
The Radix Astragali: sweet, tepor." Bencao Jingshu ": " the real table of function, person does not use pathogenic factor in the exterior; Can help gas, QI excess person does not use; Can interiorly fill in, tonifying for the deficiency, chest and diaphragm is gas-tight asks, the intestines and stomach has stagnant person not use; Energy YANG invigorating, overabundance of YANG leading to deficiency of YIN person avoids it; Part of the body cavity above the diaphragm housing the heart and lungs intenseness of heat, part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels deficiency and coldness person avoids it.
Flos Lonicerae: Flos Lonicerae is just extensive and famous with its medical value since ancient times.Its effect is mainly heat-clearing and toxic substances removing, cures mainly epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle furunculosis etc.Modern study proves, Flos Lonicerae contains the pharmacological component such as chlorogenic acid, luteolin glycosides, and the various pathogens such as Hemolytic streptococcus, staphylococcus aureus and upper respiratory tract infection Causative virus etc. are had to stronger restraint.
Radix Isatidis: hardship, cold, nontoxic.Antipyretic; Maculae caused by violent heat pathogen; High heat headache; Major part pestilence; Crimson tongue is purple dark, scarlet fever; Erysipelas; Mumps; Sore throat; Skin ulcer is swollen, carbuncle; Chickenpox; Measles; Hepatitis; Influenza, epidemic encephalitis, encephalitis b, pneumonia, coma is told nosebleed, pharyngeal swelling, acute catarrhal conjunctivitis, skin ulcer rash; Can prevent and treat epidemic encephalitis type B, acute, chronic hepatitis, mumps, osteomyelitis.
Radix Glycyrrhizae: sweet, flat.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Herba Menthae: pungent, cool.On clear, reduce phlegm, sore-throat relieving diaphragm, control wind heat: Herba Menthae end refined honey ball, as Gorgon euryale is large, often hold in the mouth or the eyes a ball.White sugar and also can.Control scrofula and form a piece, pain, wears routedly, and pus is without cease, disregards distance: a branch of as bowl large (drying in the shade) of Herba Menthae, Fructus Gleditsia ten very (not moth person of two cun of long chis, de-black skin, is coated with vinegar, process make sallow).Smash to pieces, with wine one dry measure used in former times, soak through three places, take out exposed in the sun to drying, more soak three places, so get wine to the greatest extent for degree, dry, smash sieve for loose, to cook and ball, as large in Semen Firmianae.Often, before food, with 20 balls under astragali seu Hedysari Decoction, children's reduces by half and takes it.(Holy Benevolent Prescriptions Herba Menthae ball)
Rhizoma Coptidis: heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood is told nosebleed, conjunctival congestion, toothache, quenches one's thirst, carbuncle furuncle; External treatment eczema, eczema, auditory meatus is suppurated.The kind clear part of the body cavity above the diaphragm housing the heart and lungs of Rhizoma Coptidis (processed with wine) is burning hot.For conjunctival congestion, aphtha.Prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach stomach function regulating preventing or arresting vomiting.Tie mutually damp and hot middle resistance, feeling of fullness vomiting for cold and heat.Cornel Rhizoma Coptidis soothing liver-QI stomach function regulating preventing or arresting vomiting.For incoordination between the liver and stomach, vomiting acid regurgitation.
Detailed description of the invention
Further explain the present invention below in conjunction with embodiment, but embodiment does not limit in any form to the present invention.
Embodiment 1
Drug prescription:
Borneolum Syntheticum 8g Indigo Naturalis 2.5g Alumen 2.5g Radix Notoginseng 3g Radix Astragali 2g Flos Lonicerae 5g
Radix Isatidis 4g Radix Glycyrrhizae 1.5g
Herba Menthae 1g Rhizoma Coptidis 1g.
Preparation method: get Borneolum Syntheticum, Indigo Naturalis, Alumen and be milled to powder; Get after Radix Notoginseng, the Radix Astragali, Flos Lonicerae, Radix Isatidis, Radix Glycyrrhizae, Herba Menthae and Rhizoma Coptidis are pulverized and cross 200 mesh sieves, then mix with the Borneolum Syntheticum, Indigo Naturalis and the Alumen that grind composition, make powder, pack watering can (2 grams of doses) into.
Embodiment 2
Drug prescription:
Borneolum Syntheticum 10g Indigo Naturalis 2g Alumen 2g Radix Notoginseng 2g Radix Astragali 3g Flos Lonicerae 6g Radix Isatidis 5g Radix Glycyrrhizae 1g
Herba Menthae 1g Rhizoma Coptidis 1g.
Preparation method: get Borneolum Syntheticum, Indigo Naturalis, Alumen and be milled to powder; Get Radix Notoginseng, the Radix Astragali, Flos Lonicerae, Radix Isatidis,
Radix Glycyrrhizae, Herba Menthae and Rhizoma Coptidis cross 200 mesh sieves after pulverizing, and then mix with the Borneolum Syntheticum, Indigo Naturalis and the Alumen that grind composition, make powder, pack watering can (2 grams of doses) into.
Embodiment 3
Drug prescription:
Borneolum Syntheticum 5g Indigo Naturalis 5g Alumen 5g Radix Notoginseng 2g Radix Astragali 6g Flos Lonicerae 3g Radix Isatidis 8g Radix Glycyrrhizae 5g
Herba Menthae 1g Rhizoma Coptidis 3g.
Preparation method: get Borneolum Syntheticum, Indigo Naturalis, Alumen and be milled to powder; Get Radix Notoginseng, the Radix Astragali, Flos Lonicerae, Radix Isatidis,
Radix Glycyrrhizae, Herba Menthae and Rhizoma Coptidis cross 200 mesh sieves after pulverizing, and then mix with the Borneolum Syntheticum, Indigo Naturalis and the Alumen that grind composition, make powder, pack watering can (2 grams of doses) into.
Clinical trial
The inventor in January, 2011 so far, 180 routine oral ulcer patients are carried out to clinical observation treatment.
Therapeutic Method: taking after mixing it with water with Chinese powder medicine of the present invention (embodiment 1) boiled water, 3 days is a course for the treatment of, does not recover speed treatment 3-9 days not etc. according to the state of an illness, according to the serious situation of oral ulcer, compared with the lighter, treatment time is shorter, the state of an illness is compared with severe one, and therapeutic effect is relatively poor, and treatment time is longer.
Treatment judgement:
(1) cure: ulcer heals completely.
(2) take a turn for the better: oral ulcer area reduces.
(3) invalid: symptom is unchanged.
Therapeutic effect: cure 151 examples, 27 examples that take a turn for the better, invalid 2 examples, total effective rate is more than 98%.
Powder in the embodiment of the present invention 1 contrasts Comparison of therapeutic as following table with watermelon crystal:
Powder and watermelon crystal Comparison of therapeutic in table 1 embodiment 1
| Medicament | Case load | Analgesic time | Effectively case | Recovery from illness case | Recovery from illness natural law | Cure rate |
| Embodiment 1 | 180 | 1 day | 178 | 151 | 3 | 98.8% |
| Watermelon crystal | 180 | 3 days | 150 | 135 | 6 | 83.3% |
Model case for example
Zhang, female, 45 years old, suffer from oral ulcer 5 years, used in the past BINGPENG SAN, watermelon crystal, poor effect, is used within this example after powder 6 days, cure, not recurrence;
Prunus mume (sieb.) sieb.et zucc., man, 58 years old, suffer from oral ulcer 3, pain is obvious, local rubescent, uses BINGPENG SAN not take effect, and uses recovery from illness on the 2nd after powder in this example;
Tang, man, 20 years old, suffer from oral ulcer 2, use recovery from illness on the 1st after powder in this example;
Tan, female, 32 years old, suffer from oral ulcer 5, pain is obvious, and local inflammation is used watermelon crystal not take effect, and uses recovery from illness on the 5th after powder in embodiment.
Claims (4)
1. treat a Chinese powder medicine for oral ulcer, wherein, raw material basic composition is:
Borneolum Syntheticum 2-10g Indigo Naturalis 2-5g Alumen 2-5g Radix Notoginseng 1-5g Radix Astragali 2-6g
Flos Lonicerae 3-6g Radix Isatidis 2-8g Radix Glycyrrhizae 1-5g Herba Menthae 1-3g Rhizoma Coptidis 1-3g.
2. according to the Chinese powder medicine of the treatment oral ulcer described in claim I, wherein, raw material basic composition is:
Borneolum Syntheticum 8g Indigo Naturalis 2.5g Alumen 2.5g Radix Notoginseng 3g Radix Astragali 2g Flos Lonicerae 5g
Radix Isatidis 4g Radix Glycyrrhizae 1.5g Herba Menthae 1g Rhizoma Coptidis 1g.
3. the Chinese powder medicine for the treatment of oral ulcer according to claim 1, wherein, raw material basic composition is:
Borneolum Syntheticum 10g Indigo Naturalis 2g Alumen 2g Radix Notoginseng 2g Radix Astragali 3g Flos Lonicerae 6g
Radix Isatidis 5g Radix Glycyrrhizae 1g Herba Menthae 1g Rhizoma Coptidis 1g.
4. the Chinese powder medicine for the treatment of oral ulcer according to claim 1, wherein, raw material basic composition is:
Borneolum Syntheticum 5g Indigo Naturalis 5g Alumen 5g Radix Notoginseng 2g Radix Astragali 6g Flos Lonicerae 3g
Radix Isatidis 8g Radix Glycyrrhizae 5g Herba Menthae 1g Rhizoma Coptidis 3g.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410150212.8A CN103919874B (en) | 2014-04-14 | 2014-04-14 | A kind of Chinese powder medicine treating oral ulcer |
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| CN201410150212.8A CN103919874B (en) | 2014-04-14 | 2014-04-14 | A kind of Chinese powder medicine treating oral ulcer |
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| CN103919874B CN103919874B (en) | 2016-10-26 |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104623069A (en) * | 2015-02-06 | 2015-05-20 | 苏州市天灵中药饮片有限公司 | Oral ulcer powder and preparation method of oral ulcer powder |
| CN104815040A (en) * | 2015-04-30 | 2015-08-05 | 王英英 | Traditional Chinese medicine for treating dental ulcer |
| CN106176908A (en) * | 2016-06-29 | 2016-12-07 | 胡剑 | A kind of the tasty and refreshing of oral ulcer for the treatment of dissipates |
| CN108420936A (en) * | 2017-04-19 | 2018-08-21 | 陈甲芳 | A kind of traditional Chinese powder medicine for treating canker sore |
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| CN101138622A (en) * | 2007-08-24 | 2008-03-12 | 济南市第三人民医院 | Prescription of mouth ulcer bilayer film and technique of preparing the same |
| CN101259206A (en) * | 2008-04-17 | 2008-09-10 | 张月云 | Medicine for curing oral ulcer |
| CN101822796A (en) * | 2010-03-17 | 2010-09-08 | 山西仟源制药有限公司 | Silver ice buccal tablet, and preparation method and application thereof |
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2014
- 2014-04-14 CN CN201410150212.8A patent/CN103919874B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101138622A (en) * | 2007-08-24 | 2008-03-12 | 济南市第三人民医院 | Prescription of mouth ulcer bilayer film and technique of preparing the same |
| CN101259206A (en) * | 2008-04-17 | 2008-09-10 | 张月云 | Medicine for curing oral ulcer |
| CN101822796A (en) * | 2010-03-17 | 2010-09-08 | 山西仟源制药有限公司 | Silver ice buccal tablet, and preparation method and application thereof |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104623069A (en) * | 2015-02-06 | 2015-05-20 | 苏州市天灵中药饮片有限公司 | Oral ulcer powder and preparation method of oral ulcer powder |
| CN104815040A (en) * | 2015-04-30 | 2015-08-05 | 王英英 | Traditional Chinese medicine for treating dental ulcer |
| CN104815040B (en) * | 2015-04-30 | 2017-10-03 | 吉林大学 | Treat the Chinese medicine of canker sore |
| CN106176908A (en) * | 2016-06-29 | 2016-12-07 | 胡剑 | A kind of the tasty and refreshing of oral ulcer for the treatment of dissipates |
| CN108420936A (en) * | 2017-04-19 | 2018-08-21 | 陈甲芳 | A kind of traditional Chinese powder medicine for treating canker sore |
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| CN103919874B (en) | 2016-10-26 |
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