CN102526643B - Chinese herbal medicine buccal tablet for treating dental ulcer - Google Patents

Chinese herbal medicine buccal tablet for treating dental ulcer Download PDF

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CN102526643B
CN102526643B CN 201210077003 CN201210077003A CN102526643B CN 102526643 B CN102526643 B CN 102526643B CN 201210077003 CN201210077003 CN 201210077003 CN 201210077003 A CN201210077003 A CN 201210077003A CN 102526643 B CN102526643 B CN 102526643B
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herba
radix
herbal medicine
ulcer
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CN102526643A (en
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吴健
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GUANGXI WUZHOU 3HE PHARMACEUTICAL CO., LTD.
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CHANGSHU YUSHAN GREEN TEA Co Ltd
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Abstract

The invention discloses a Chinese herbal medicine buccal tablet for treating dental ulcer, which is prepared through repeated verification of years' clinic experiments and is prepared by chorion ovi, calomel, minium, lithargite, red halloysite, mentha haplocalyx, dandelion, catechu, honeysuckle, Siraitia grosvenorii root, mosla dianthera, aloe, loranthus parasiticus, lowigite, curcuma aromatica, radix rhapontied, no name, alone leave hyacinth bletilla, rosa multiflora leaves, radix astragali, anemone hupehensis, ophioglossum vulgatum and ball cactus. The Chinese medicine matching accords witha traditional Chinese medicine theory, a prescription adopts Chinese medicines as raw materials, required components are prepared through dipping, decoction, crushing, pressing and the like, and drugs, tablets, capsules and the like are prepared through formulation. The Chinese herbal medicine buccal tablet for treating dental ulcer starts from removing corrosion and fast removing deformed mucosa, and diminishes inflammation and stops pain for dental ulcer so as to promote ulcer to heal.

Description

A kind of Chinese herbal medicine buccal tablet for the treatment of oral ulcer
Technical field
The invention belongs to the field of Chinese medicines, specifically a kind of Chinese herbal medicine buccal tablet for the treatment of oral ulcer.
Background technology
The inflammation in oral cavity can be by infection, and systemic disease or physical agent cause, form stomatitis when expansion is come, by the caused all kinds of pharyngitis of pathogenic bacterium such as anaerobe, antibacterial, laryngitis, oral ulcer, aphtha, halitosis, periodontitis, gingivitis.
Oral ulcer, aphtha be a kind of be the oral mucosa limitation ulcer infringement of characteristics with outbreak periodically repeatedly, can spontaneous recovery, can betide any position of oral mucosa, see that with lip, cheek, tongue severe patient can involve pharyngeal mucosa more.Much patients are along with the prolongation of the course of disease, and the ulcer area increases, and number increases, and pain increases the weight of, and healing stage prolongs, and shorten interval etc., and influence is eaten and spoken.Though the Therapeutic Method to stomatitis, oral ulcer, pharyngitis, laryngitis, aphtha, halitosis, periodontitis, gingivitis is a lot, but all be symptomatic treatment basically, purpose mainly is to ease the pain or reduce recurrent number, but can not control recurrence fully, so the prevention primary disease is particularly important.
Though a lot of to the Therapeutic Method of oral ulcer, purpose mainly is to ease the pain or reduce recurrent number, can not control recurrence fully, so the prevention primary disease is particularly important.
Summary of the invention
The present invention provides a kind of Chinese herbal medicine buccal tablet for the treatment of oral ulcer in order to solve the deficiencies in the prior art part.
A kind of Chinese herbal medicine buccal tablet for the treatment of oral ulcer of the present invention forms by clinic tests and repeated verification for many years configuration, meets the theory of Chinese medicine.Prescription is to be raw material with the Chinese herbal medicine, through soaking, stay up late, pulverize and flow process such as compacting being made required composition, makes medicament, tablet, capsule again after composite.The present invention repairs the distortion mucosa fast and starts with from putrefaction-removing granulation-promoting, oral ulcer is carried out antiinflammatory, thereby pain relieving promotes ulcer healing.
A kind of Chinese herbal medicine buccal tablet for the treatment of oral ulcer is characterized in that, is to be made by following weight portion raw material:
Membrana Follicularis ovi 10-20 part, Calomelas 10-20 part, Plumbum preparatium 10-20 part, Lithargyrum 10-20 part, Halloysitum Rubrum 10-20 part, Herba Menthae 10-20 part, Herba Taraxaci 8-18 part, catechu 8-18 part, Flos Lonicerae 8-18 part, Momordica grosvenori root 8-18 part, Mosla dianthera 8-18 part, Aloe 8-18 part, Herba Taxilli 5-16 part, fibroferritum 5-16 part, Radix Curcumae 5-16 part, Radix Rhapontici 5-16 part, Fructus Pistaciae Verae 5-16 part, Rhizoma Pleiones Yunnanensis 5-16 part, Folium rosae multiflorae 1-10 part, Radix Astragali 1-10 part, Herba Anemones Hupehensis 1-10 part, Herba Ophioglossi 1-10 part, Caulis Echinopsis Multiplicis 1-10 part;
Preparation method:
(1) it is standby by formula proportion the decocting of two times of Membrana Follicularis ovis, Herba Menthae, Herba Taraxaci, catechu, Flos Lonicerae, Momordica grosvenori root, Mosla dianthera, Aloe, Herba Taxilli, Radix Curcumae, Radix Rhapontici, Fructus Pistaciae Verae, Rhizoma Pleiones Yunnanensis, Folium rosae multiflorae, the Radix Astragali, Anemone hupehensi, Herba Ophioglossi, Caulis Echinopsis Multiplicis to be boiled into medicinal liquid;
(2) it is standby by formula proportion Calomelas, Plumbum preparatium, Lithargyrum, Halloysitum Rubrum, fibroferritum to be crushed to 300-400 order fine powder;
(3) concentrating add pulverizing the standby fine powder in the back concentrator that stirs → pour into then in the standby medicinal liquid by formula proportion, namely obtaining the semi-finished product runny plaste, semi-finished product runny plaste → make tablet according to common film-making pressing process, can obtain finished product again.
A kind of Chinese herbal medicine buccal tablet for the treatment of oral ulcer is characterized in that, is to be made by following weight portion raw material:
Membrana Follicularis ovi 11-19 part, Calomelas 11-19 part, Plumbum preparatium 11-19 part, Lithargyrum 11-19 part, Halloysitum Rubrum 11-19 part, Herba Menthae 11-19 part, Herba Taraxaci 9-17 part, catechu 9-17 part, Flos Lonicerae 9-17 part, Momordica grosvenori root 9-17 part, Mosla dianthera 9-17 part, Aloe 9-17 part, Herba Taxilli 6-15 part, fibroferritum 6-15 part, Radix Curcumae 6-15 part, Radix Rhapontici 6-15 part, Fructus Pistaciae Verae 6-15 part, Rhizoma Pleiones Yunnanensis 6-15 part, Folium rosae multiflorae 2-8 part, Radix Astragali 2-8 part, Herba Anemones Hupehensis 2-8 part, Herba Ophioglossi 2-8 part, Caulis Echinopsis Multiplicis 2-8 part;
A kind of Chinese herbal medicine buccal tablet for the treatment of oral ulcer is characterized in that, is to be made by following weight portion raw material:
17 parts of Membrana Follicularis ovis, 17 parts of Calomelass, 17 parts of Plumbum preparatiums, 17 parts of Lithargyrums, 17 parts of Halloysitum Rubrums, 17 parts of Herba Menthaes, 15 parts of Herba Taraxacis, 15 parts in catechu, 15 parts of Flos Loniceraes, 15 parts of Momordica grosvenori roots, 15 parts of Mosla diantheras, 15 parts of Aloes, 10 parts of Herba Taxillis, 10 parts of fibroferritum, 10 parts of Radix Curcumaes, 10 parts of Radix Rhapontici, 10 parts of Fructus Pistaciae Veraies, 10 parts of Rhizoma Pleiones Yunnanensiss, 5 parts of Folium rosae multifloraes, 5 parts of the Radixs Astragali, 5 parts of Herba Anemones Hupehensiss, 5 parts of Herba Ophioglossis, 5 parts of Caulis Echinopsis Multipliciss;
The present invention relates to raw material of Chinese medicine pharmacology and the property of medicine:
Membrana Follicularis ovi:
[meridian distribution of property and flavor] be " decoction pieces is newly joined " 1.: " light, flat." 2. " Sichuan Chinese medicinal herbal ": " warm in nature, sweet in the mouth is nontoxic." go into lung, spleen, stomach warp.1. " can cure mirror approximately ": " go into lung." 2. " Sichuan Chinese medicinal herbal ": " go into spleen, stomach, lung three warps.”
[curing mainly] controls chronic cough, pharyngalgia aphonia, scrofula tuberculosis, ulcer being unable to heal.
Calomelas:
[nature and flavor] suffering, cold, poisonous.1. " the good book on Chinese herbal medicine of helping ": " suffering, cold, nontoxic." 2. " Elementary Medicine ": " is poisonous." 3. " Bencao Congxin ": " is hot cold and dry, poisonous."
[return through] goes into liver, kidney channel.1. " beautiful Chinese catalpa medicine solution ": " go into kidney meridian, liver channel of foot-Jueyin." 2. " book on Chinese herbal medicine is new again ": go into liver, lung two warps.
[function] parasite killing, counteracting toxic substances, diuretic, relieving constipation.Control scabies, scrofula, syphilis, primary sore, skin ulcer, edema, tympanites, defecation is closed.1. supplement to the Herbal: " logical large intestine changes children's's infantile malnutrition and scrofula, kills wine acne on skin ulcer copperworm and the nose, wind skin ulcer pruritus." 2. amplification on Canon of Materia Medica: " saliva medicine and children's's saliva tide, Chi Zong down used more." 3. Zhang Yuansu: " promoting diuresis to alleviate water retention goes in the bladder dirt greasy." 4. " Elementary Medicine ": " consumer edema, hemostasis dysentery is told wind saliva.It is stagnant that " 5. " detailed outline ": " controls sputum, edema tympanites, skin infection." 6. " book on Chinese herbal medicine just ": " controls all skin infection of scrofula, removing the necrotic tissue meat, tissue regeneration promoting meat.
The Plumbum preparatium:
[meridian distribution of property and flavor] acrid in the mouth, little salty, little puckery is gone into the heart, spleen, Liver Channel;
[effect] detoxifcation, granulation promoting, eliminating phlegm down to arrest convulsion.Control carbuncle, ulcer, incised wound is hemorrhage, aphtha, and corneal nebula, the soup fire , Jing Epilepsy of burning is demented, malaria, dysentery is told converse stomach.
The Lithargyrum:
[meridian distribution of property and flavor] property is salty, hot, flat, poisonous; Go into liver, spleen channel.
[effect] detumescence, parasite killing, convergence are anticorrosion, eliminating phlegm down to arrest convulsion, through test to multiple pathogenic dermatophytes, inhibitory action is in various degree arranged, can shrink the blood vessel at mucosa and ulcer place, secretion is reduced, and effect such as protecting from infection of antiinflammatory is arranged.
Halloysitum Rubrum:
[nature and flavor] are sweet; Puckery; Acid; Temperature; Nontoxic.  
[effect] astringing intestine to stop diarrhea; Astringing to arrest bleeding; Removing dampness is held back skin ulcer; Granulation promoting. 
[curing mainly] chronic diarrhea; Chronic dysentery; Have blood in stool; Proctoptosis; Seminal emission; Metrorrhagia; Leukorrhagia; Ulcer being unable to heal; Eczema; Traumatic hemorrhage.
Herba Menthae:
[meridian distribution of property and flavor] cool in nature, acrid in the mouth;
The effect of [function] irritation causes trachea to produce new secretion, and makes the mucus of stiff be easy to get rid of, so the effect of eliminating the phlegm, sterilizing is arranged.
Herba Taraxaci:
[nature and flavor] are sweet, and little hardship is cold.
[curing mainly] heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, upper respiratory tract infection, eye conjunctivitis, mumps, acute mastitis swells and ache, gastritis, dysentery, hepatitis, gallbladder is assisted inflammation, acute appendicitis, urinary system infection, pelvic inflammatory disease, carbuncle furuncle furuncle, pharyngitis is controlled acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, urinary tract infection.
Catechu:
[meridian distribution of property and flavor] is bitter, puckery, is slightly cold.Return lung meridian.
[function cures mainly] removing dampness promoting tissue regeneration and ulcer healing is used for ulcer being unable to heal, eczema, aphtha, traumatic pain, traumatic hemorrhage.
Flos Lonicerae:
[nature and flavor] property is sweet, cold;
[function] has heat clearing away, detoxifcation, antiinflammatory, antibiotic effect.Compendium of Material Medica is carried " Flos Lonicerae is good at removing toxic substances, so control carbuncle, toxic swelling, skin ulcer tinea ... ".Since ancient times, Flos Lonicerae is usually used in heat-clearing and toxic substances removing, the heating for the treatment of epidemic febrile disease, and toxic-heat and blood stasis, diseases such as carbuncle and ulcer also are used for anemopyretic cold, diseases such as bronchitis.Modern pharmacological research shows, that Flos Lonicerae has is antibacterial, antiviral, antiinflammatory, analgesic, regulate effect such as immunity.
Momordica grosvenori root:
[nature and flavor] are sweet, cool, go into lung;
The root of the Fructus Momordicae that [function] smashed to pieces spreads on the affected part and can control stubborn dermatitis, and pain is swollen, furuncle etc.
Mosla dianthera:
[nature and flavor] suffering, temperature. 
[effect] dispeled the wind and delivered, and dampness removing is antipruritic.Be used for headache due to common cold, tonsillitis, heatstroke, Peptic Ulcers, dysentery; Eczema is controlled in external, miliaria, skin pruritus, furuncle, centipete bite.
Aloe: the Pharmacopoeia of the People's Republic of China (version was an one in 2000) is said nature and flavor in this way and returned through hardship, and is cold; Return liver, stomach, large intestine channel; Function with cure mainly: removing heat from the liver, relieving constipation; Be used for constipation, infantile malnutrition, infantile convulsion; The external treatment exudative dermatitis.Compendium of Material Medica is said nature and flavor in this way: hardship, and cold, nontoxic; Cure mainly: the hot blast unhappiness, steam between septum pectorale, the relieving palpitation that makes eye bright, the children epilepsy infantile convulsion is treated five kinds of child malnutrition, kills the sick skin ulcer fistula of three worms and hemorrhoid, separates the Fructus Crotonis poison." China's book on Chinese herbal medicine " says that in this way " China's book on Chinese herbal medicine " of the great achievement of concentrating herbal medicine is summarised as the health care of aloe: ⑴ lets out down, namely relaxes bowel; ⑵ adjusting immunity of human body; ⑶ tumor resistance; ⑷ protect liver; ⑸ anti-gastric injury; ⑹ antibiotic; ⑺ repair tissue damage; ⑻ the protective effect to skin.Hardship, cold.Return liver, stomach, large intestine channel.Function with cure mainly: let out down, namely relax bowel; Adjusting immunity of human body; tumor resistance; The protection liver; Anti-gastric injury; Antibiotic; The repair tissue damage; Protective effect to skin.
Herba Taxilli:
[nature and flavor] are bitter, sweet, and are flat.
[return through] returns liver, kidney channel.
[function cures mainly] invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling, antiabortive unit.Be used for rheumatic arthralgia, soreness of the waist and knees, muscles and bones is unable, and the metrorrhagia warp is many, blood leaking in gestation, frequent fetal movement; Hypertension.
Fibroferritum:
[nature and flavor] acid; Puckery; Salty; Cold; Poisonous
[return through] liver; Large intestine channel
[function cures mainly] detoxifcation parasite killing; Hold back skin ulcer.Main hemorrhoid complicated by anal fistula; Malignant boil; Scabies; The Ting ear comes to a head
Radix Curcumae:
[meridian distribution of property and flavor] is hot, bitter, and be cold; GUIXIN, lung, Liver Channel.
[effect] promoting blood circulation and stopping pain, dispersing the stagnated live-QI to relieve the stagnation of QI, removing heat from blood clears away heart-fire, promoting the function of the gallbladder to alleviate jaundice.
Radix Rhapontici:
[nature and flavor] " herbal classic ": " bitter in the mouth is salty, and is cold." " not Lu ": " Great Cold, nontoxic." " book on Chinese herbal medicine is just ": " it is little salty, cold in nature, slightly poisonous to distinguish the flavor of.”?  
[return through] goes into stomach, large intestine channel.  
[function] heat-clearing and toxic substances removing, eliminating carbuncle, stimulating milk secretion, Shujin is promoted blood circulation.  
[curing mainly] is used for acute mastitis and swells and ache carbuncle carbuncle on the back, scrofula sore, galactostasis, arthralgia chiefly caused by damp pathogen contracture, arthralgia, toxic-heat and blood stasis, bleeding hemorrhoids.
Fructus Pistaciae Verae:
[nature and flavor] supplement to the Herbal: acrid in the mouth, warm, puckery, nontoxic.  
The effect of Fructus Pistaciae Verae [function cures mainly-] the kidney warming, warm spleen.It is cold to control the waist of suffering from a deficiency of the kidney, sexual impotence, insufficiency of the spleen cold-dysentery.1. supplement to the Herbal: main all dysentery, remove cold air, make us fertile strong.2. " Haiyao Bencao, Oversea Materia Medica ": main waist is cold, a little less than the moon is suffered from a deficiency of the kidney, gets water perfume (or spice), Fructus Corni is good.3. " detailed outline is picked up any lost article from the road ": dysentery relieving, warming the kidney, appetizing is amassed except intestinal is dirty; Get the Radix Aucklandiae, mountain cornel energy Xing Yang.
Rhizoma Pleiones Yunnanensis:
[nature and flavor] " Yunnan Chinese herbal medicine ": hardship, flat.
[function cures mainly] tonifying the lung, relieving cough and resolving phlegm, hemostasia and promoting granulation.Control pneumosilicosis, pulmonary tuberculosis, pertussis, trachea, digestive tract hemorrhage, carbuncle, traumatic hemorrhage.1. " Yunnan Chinese herbal medicine ": relieving cough and resolving phlegm, tonifying the lung granulation promoting.2. " the Guizhou medicine is planted catalogue ": heat-clearing and toxic substances removing, cough-relieving.3. " choosing of Yunnan Chinese herbal medicine ": lung moistening, hemostasis.Control pneumosilicosis, pulmonary tuberculosis, tracheitis, digestive tract hemorrhage, traumatic hemorrhage, furuncle and phyma, traumatic injury.
Folium rosae multiflorae:
[meridian distribution of property and flavor] puckery, flat spleen channel.
[function cures mainly] " Nanning City's medicine will ": " mash external application, promoting tissue regeneration and wound healing."
The Radix Astragali has another name called Radix Astragali:
[meridian distribution of property and flavor] is sweet, temperature.Return lung, spleen channel.
[function cures mainly] invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.It is weak to be used for the deficiency of vital energy, anorexia and loose stool, and sinking of QI of middle-JIAO, the chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, the exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle is difficult bursts, and burst for a long time and do not hold back, the blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.
Herba Anemones Hupehensis:
[meridian distribution of property and flavor] toil, cold, poisonous.Return spleen; Stomach; Large intestine channel, stem, leaf: bitter, hot, temperature.Very toxic.Root: hardship, temperature.Poisonous.1. " Shaanxi Chinese herbal medicine ": " hardship, cold, slightly poisonous." 2. " Chinese herbal medicine is used in Sichuan always ": " and toil, temperature, slightly poisonous.”?  
[chemical composition of Chinese materia medica] root and herb contain Anemonin (anemonin) and triterpene soap oleanolic acid-3-O-β-D-ribopyranose base-(1 → 3)-α-L-rhamnopyranosyl-(1 → 3)-α-L-arabopyranose glycoside, oleanolic acid 3-O-β-D-ribopyranose base-(1 → 3)-α-L-rhamnopyranosyl-(1 → 2)-β-D-xylopyranose glucoside, and oleanolic acid.
[function cures mainly] herb is mashed and is dropped in manure pit or the sewage, kills maggot, wriggler.Stem, leaf: parasite killing; Control stubborn dermatitis.Eliminate indigestion, detumescence, dissipating blood stasis.Control stubborn dermatitis, tinea alba, malaria, infantile malnutrition, dysentery, the carbuncle furuncle is swollen, and scrofula, traumatic injury be " Shaanxi Chinese herbal medicine " 1.: " heat-clearing and toxic substances removing, evacuation of pus granulation promoting, detumescence dissipating blood stasis, promoting digestion and removing stagnation, preventing the attack (or recurrence) of malaria, parasite killing.Control stubborn dermatitis, tinea alba, furuncle carbuncle, innominate toxic swelling, malaria, dysentery, infantile malnutrition, dyspepsia, traumatic injury." 2. " Chinese herbal medicine is used in Sichuan always ": " detumescence is loose malicious.Control the traumatic injury redness, scrofula sore, dysentery diarrhoea.”
Herba Ophioglossi:
[nature and flavor] are little sweet, bitter, cold.
[function cures mainly] claims Ophioglossum vulgatum again; Removing heat from blood, heat-clearing and toxic substances removing, reducing swelling and alleviating pain.Cure mainly: laryngalgia, sore throat, diphtheria, oral disease, infantile pneumonia, abdominal distention, venom is treated pyogenic infections from tumour or sore; Acute conjunctivitis is controlled in external, corneal nebula, margo palpebrae inflammation.
Caulis Echinopsis Multiplicis:
[nature and flavor] are sweet light, and are flat.1. " Fujian traditional herbal medicine ": " sweet, cold." 2. " Luchuan book on Chinese herbal medicine ": " cold in nature, little acid " is " Hunan medicine will " 3.: " light, flat.”?  
[function cures mainly] controls the cough due to lung-heat, sputum mixed with blood, carbuncle, burn.1. " Fujian traditional herbal medicine ": " laxation, pathogenic fire purging, eliminating carbuncle." 2. " Luchuan book on Chinese herbal medicine ": " lung that clears away heart-fire, hemostasis.Control the cough due to lung-heat, sputum mixed with blood." 3. " Hunan medicine will ": " damp eliminating is brought down a fever for reducing swelling and alleviating pain, promoting flow of QI and blood, granulation promoting.”?  
[usage and consumption] is for oral administration: fry in shallow oil soup, 3~5 money (2~3 liang of bright persons).External: smash to apply or smash juice and be coated with.
The specific embodiment:
Embodiment 1, prescription:
Membrana Follicularis ovi 10g, Calomelas 10g, Plumbum preparatium 10g, Lithargyrum 10g, Halloysitum Rubrum 10g, Herba Menthae 10g, Herba Taraxaci 8g, catechu 8g, Flos Lonicerae 8g, Momordica grosvenori root 8g, Mosla dianthera 8g, Aloe 8g, Herba Taxilli 5g, fibroferritum 5g, Radix Curcumae 5g, Radix Rhapontici 5g, Fructus Pistaciae Verae 5g, Rhizoma Pleiones Yunnanensis 5g, Folium rosae multiflorae 1g, Radix Astragali 1g, Herba Anemones Hupehensis 1g, Herba Ophioglossi 1g, Caulis Echinopsis Multiplicis 1g;
Preparation method:
(1) it is standby by formula proportion the decocting of two times of Membrana Follicularis ovis, Herba Menthae, Herba Taraxaci, catechu, Flos Lonicerae, Momordica grosvenori root, Mosla dianthera, Aloe, Herba Taxilli, Radix Curcumae, Radix Rhapontici, Fructus Pistaciae Verae, Rhizoma Pleiones Yunnanensis, Folium rosae multiflorae, the Radix Astragali, Anemone hupehensi, Herba Ophioglossi, Caulis Echinopsis Multiplicis to be boiled into medicinal liquid;
(2) it is standby by formula proportion Calomelas, Plumbum preparatium, Lithargyrum, Halloysitum Rubrum, fibroferritum to be crushed to 300-400 order fine powder;
(3) concentrating add pulverizing the standby fine powder in the back concentrator that stirs → pour into then in the standby medicinal liquid by formula proportion, namely obtaining the semi-finished product runny plaste, semi-finished product runny plaste → make tablet according to common film-making pressing process, can obtain finished product again.
Usage and dosage: every day four times, each 1, every 200mg.
Embodiment 2, prescription:
Membrana Follicularis ovi 11g, Calomelas 11g, Plumbum preparatium 11g, Lithargyrum 11g, Halloysitum Rubrum 11g, Herba Menthae 11g, Herba Taraxaci 9g, catechu 9g, Flos Lonicerae 9g, Momordica grosvenori root 9g, Mosla dianthera 9g, Aloe 9g, Herba Taxilli 6g, fibroferritum 6g, Radix Curcumae 6g, Radix Rhapontici 6g, Fructus Pistaciae Verae 6g, Rhizoma Pleiones Yunnanensis 6g, Folium rosae multiflorae 2g, Radix Astragali 2g, Herba Anemones Hupehensis 2g, Herba Ophioglossi 2g, Caulis Echinopsis Multiplicis 2g;
Preparation method, usage and dosage are identical with embodiment 1.
Embodiment 3, prescription:
Membrana Follicularis ovi 17g, Calomelas 17g, Plumbum preparatium 17g, Lithargyrum 17g, Halloysitum Rubrum 17g, Herba Menthae 17g, Herba Taraxaci 15g, catechu 15g, Flos Lonicerae 15g, Momordica grosvenori root 15g, Mosla dianthera 15g, Aloe 15g, Herba Taxilli 10g, fibroferritum 10g, Radix Curcumae 10g, Radix Rhapontici 10g, Fructus Pistaciae Verae 10g, Rhizoma Pleiones Yunnanensis 10g, Folium rosae multiflorae 5g, Radix Astragali 5g, Herba Anemones Hupehensis 5g, Herba Ophioglossi 5g, Caulis Echinopsis Multiplicis 5g;
Preparation method, usage and dosage are identical with embodiment 1.
Embodiment 4, prescription:
Membrana Follicularis ovi 19g, Calomelas 19g, Plumbum preparatium 19g, Lithargyrum 19g, Halloysitum Rubrum 19g, Herba Menthae 19g, Herba Taraxaci 17g, catechu 17g, Flos Lonicerae 17g, Momordica grosvenori root 17g, Mosla dianthera 17g, Aloe 17g, Herba Taxilli 15g, fibroferritum 15g, Radix Curcumae 15g, Radix Rhapontici 15g, Fructus Pistaciae Verae 15g, Rhizoma Pleiones Yunnanensis 15g, Folium rosae multiflorae 8g, Radix Astragali 8g, Herba Anemones Hupehensis 8g, Herba Ophioglossi 8g, Caulis Echinopsis Multiplicis 8g;
Preparation method, usage and dosage are identical with embodiment 1.
Embodiment 5, prescription:
Membrana Follicularis ovi 20g, Calomelas 20g, Plumbum preparatium 20g, Lithargyrum 20g, Halloysitum Rubrum 20g, Herba Menthae 20g, Herba Taraxaci 18g, catechu 18g, Flos Lonicerae 18g, Momordica grosvenori root 18g, Mosla dianthera 18g, Aloe 18g, Herba Taxilli 16g, fibroferritum 16g, Radix Curcumae 16g, Radix Rhapontici 16g, Fructus Pistaciae Verae 16g, Rhizoma Pleiones Yunnanensis 16g, Folium rosae multiflorae 10g, Radix Astragali 10g, Herba Anemones Hupehensis 10g, Herba Ophioglossi 10g, Caulis Echinopsis Multiplicis 10g;
Preparation method, usage and dosage are identical with embodiment 1.
Treatment oral ulcer observation of curative effect:
The oral ulcer main feature has self limiting for outbreak repeatedly, can heal voluntarily; Therefore, the control recurrence has very important meaning to the treatment primary disease.We adopt the present invention to treat mouth ulcer lozenge in 2010-2011, and treatment oral ulcer 1000 examples obtain good result, now are summarized as follows.
The treatment oral ulcer has unique effects:
10~30 seconds: pain was eliminated, and implication disappears.The effective ingredient of medicine can be blocked fibrinous lymphocytic the oozing out of focus rapidly, reducing swelling and alleviating pain, and removing the necrotic tissue and promoting granulation is effectively controlled new ulcer surface and is generated.
2~3 days: oral ulcer all healed, and tongue fur is normal, its concurrent halitosis, pharyngitis, etc. transference cure, reach clinical rehabilitation.
3~15 days: the further after treatment of obstinate recurrent oral ulceration patient, thoroughly remove nosotoxin in the body, endocrine regulation, enhancing human body immunity power strengthens the oral mucosa metabolic function, keeps oral mucosa complete, effectively prevention of recurrence.
The health giving quality observation index
Main curative effect index: ulcer size, number, ooze out, edema, hyperemia, pain, burn feeling, xerostomia.
Secondary efficacy index: stool, urine, picture of the tongue, pulse condition.
The model case curative effect determinate standard:
Local disease is decreased evaluation criteria and is as the criterion with ulcer healing degree and the scorching hot degree of pain.
Clinical recovery: medication is transference cure after 5 days, and sign disappears substantially, and Peptic Ulcers is decreased all healings, and the leading indicator integration is 0 or 1.
Produce effects: medication 10-30 transference cure after second, sign all has clear improvement, ulcer healing reach 2/3 or ulcer shoal and dwindle, it is 2 that the leading indicator integration is 1, two.
Effectively: medication is transference cure after 3 days, and sign all take a favorable turn, ulcer healing reach 1/3 or ulcer shoal and dwindle, it is 3 that the leading indicator integration is 2, two.
Invalid: medication cardinal symptom after 3 days, sign are improved not obvious, and the basic no change of ulcer, leading indicator integration are 3 or 4.
Therapeutic outcome.
The present invention draws through clinical trial:
Recovery from illness clinical improvements rate 〉=95%;
Produce effects clinical improvements rate<97%, 〉=80%;
Invalid clinical improvements rate<10%;
Model case:
Case 1:
Open XX, 38 years old, it was surplus to suffer from recurrent oral ulceration 10 years, and pain is obvious, after develop into the eyes blurring of vision and had a surplus in 2 years, vulval ulcer 3 years is diagnosed as recurrent oral ulceration.Symptom obviously alleviates after friend introduces my institute to treat 3 days, has treated rehabilitation after 10 days again continuously.
Case 2:
King XX, 38 years old, the two cheek erosions of patient oral cavity, pain, dry mouth and parching tongue failed to cure through how tame large hospital treatment for many years.The final inspection discovery, this patient's oral mucosa is hyperemia extensively, and two cheek posterior segment large tracts of land present greyish white ring-like netted, and the wax sample is sick to be decreased and companion's redness, erosion, pus tongue and sepage, attaches most importance to the left side, and preceding jaw is big lamellar canescence wax sample and changes.The lingual surface drying, and with the stringer crackle.Expert diagnosis is lichen planus, erosive type.The Chinese medicine buccal tablet of oral prescription after 3 days its symptom obviously alleviate, the rotten to the corn degree of two cheeks takes a turn for the better, pain symptom is alleviated, after carried out a period of time treatment back symptom again and eliminated, oral mucosa and lingual surface are intact
Complete normal, not recurrence so far.
Case 3:
Xu XX, the man, 52 years old, it is surplus that aphtha 1 year respectively takes place in the both sides of right side, buccal, oral cavity and tongue.Western medicine diagnose is " oral ulcer ", but controls it with Amoxicillin Capsules and vitamin B2, and the beginning a few days is effective, obeys it again, and is then invalid. obey the folk prescription for the treatment of dental ulcer again, each surplus 10 doses on folk prescription is not got effect yet.Changing takes traditional Chinese medicine controls it, once obeys daochi powder, XIEXIN TANG, Liujunzi Tang and adds and subtracts each several doses, does not also see remarkable effect.The present examines, and except above-mentioned points, still sees dysphoria and insomnia, and complexion is sent out red, the self-induction palpitating speed, and the bitter taste lack of appetite, it is greasy to detest hydraulic fluid port, unsatisfactory slightly namely angry, constipation with dry stool, red tongue, yellow fur is thick, and the arteries and veins flood is sliding etc.This is that heart channel excess-fire merges dampness-heat in the liver and gallbladder
Time.Answer eliminating heart-fire, eliminating pathogen in the liver gallbladder damp and hot.The Chinese medicine of oral prescription became visible ulcer in 3 days and disappears.
Case 4:
Liu XX, 30 years old, ulcer appearred in patient's tongue body and lower lip inboard, showing effect repeatedly, it is red and swollen, rotten to the corn to occur around 2 years posterior perineum portions and the genitals, symptoms such as erythema nodosum and the gonalgia appear in two skin of lower extremity, with alleviation is arranged behind hormone and the antibiotic therapy slightly, but frequent outbreak.Since nearly a year and a half, above-mentioned symptom increases the weight of, and that transfusion acupuncture position occurs is red and swollen, pus bubble and with senses of discomfort such as blurred vision, xerophthalmias.Once treated in hospital of many families, but poor effect.Be diagnosed as recurrent ulcer through expert's inspection.Chinese medicine rehabilitation after 3 days of oral prescription, not recurrence so far.
Case 5:
Open XX, 29 years old, patient's oral ulcer was shown effect nearly 5 years repeatedly, and huge pain can not be taken food unbearably during sick sending out, and with symptoms such as headache, xerostomia halitosis, agitation, heating, lymph enlargements.Chinese medicine preparation by oral prescription is after 2 days, and the state of an illness is clearly better, and patient's confidence heightens, and continues the recovery from illness for the treatment of back, so far recurrence.
Case 6:
Hu XX, 30 years old, engender symptoms such as genitals erosion, congested ulcer after suffering from oral ulcer, and increase the weight of gradually, outbreak repeatedly, it has taken several folk prescriptions among the people in the locality, the symptom commentaries on classics of not getting better, I went to a doctor at institute afterwards, be recurrent oral ulceration by expert diagnosis, Chinese medicine rehabilitation after 3 days of oral prescription, recurrence so far.
Case 7:
The Meng XX, 308 years old, the patient is often outbreak repeatedly in the period of suffering from recurrent oral ulceration three.Check discovery through the expert, patient's conjunctival congestion and pain of eye, vulval ulcer, skin have the many places furuncle and phyma, and symptom such as, red tongue few with bitter taste in the mouth and dry throat, agitation, yellow urine, yellow and greasy fur, stringy and rolling pulse, and expert diagnosis is recurrent oral ulceration, liver dampness-heat in the spleen type.Chinese medicine rehabilitation after 3 days of oral prescription is recurrence so far.
Case 8:
Zhao XX, 26 years old, mucosa many places ulcer in patient's mouth successively once failed to cure at how tame hospital therapy, and recurrence often increases the weight of, and has influenced work and life.Find that on inspection there is many places ulcer its tip of the tongue, left margin of tongue, tongue abdomen and lower lip inboard, are respectively 3 * 3mm 2,2 * 4mm 2 and 4 * 5mm, 2 sizes, the center pus tongue that is white in color, reddening and swelling of mucosa on every side, expert diagnosis is recurrent oral ulceration.The Chinese medicine of oral prescription was fully recovered after 2 days.

Claims (4)

1. a Chinese herbal medicine buccal tablet for the treatment of oral ulcer is characterized in that, is to be made by following weight portion raw material:
Membrana Follicularis ovi 10-20 part, Calomelas 10-20 part, Plumbum preparatium 10-20 part, Lithargyrum 10-20 part, Halloysitum Rubrum 10-20 part, Herba Menthae 10-20 part, Herba Taraxaci 8-18 part, catechu 8-18 part, Flos Lonicerae 8-18 part, Momordica grosvenori root 8-18 part, Mosla dianthera 8-18 part, Aloe 8-18 part, Herba Taxilli 5-16 part, fibroferritum 5-16 part, Radix Curcumae 5-16 part, Radix Rhapontici 5-16 part, Fructus Pistaciae Verae 5-16 part, Rhizoma Pleiones Yunnanensis 5-16 part, Folium rosae multiflorae 1-10 part, Radix Astragali 1-10 part, Herba Anemones Hupehensis 1-10 part, Herba Ophioglossi 1-10 part, Caulis Echinopsis Multiplicis 1-10 part.
2. a kind of Chinese herbal medicine buccal tablet for the treatment of oral ulcer according to claim 1 is characterized in that, is to be made by following weight portion raw material:
Membrana Follicularis ovi 11-19 part, Calomelas 11-19 part, Plumbum preparatium 11-19 part, Lithargyrum 11-19 part, Halloysitum Rubrum 11-19 part, Herba Menthae 11-19 part, Herba Taraxaci 9-17 part, catechu 9-17 part, Flos Lonicerae 9-17 part, Momordica grosvenori root 9-17 part, Mosla dianthera 9-17 part, Aloe 9-17 part, Herba Taxilli 6-15 part, fibroferritum 6-15 part, Radix Curcumae 6-15 part, Radix Rhapontici 6-15 part, Fructus Pistaciae Verae 6-15 part, Rhizoma Pleiones Yunnanensis 6-15 part, Folium rosae multiflorae 2-8 part, Radix Astragali 2-8 part, Herba Anemones Hupehensis 2-8 part, Herba Ophioglossi 2-8 part, Caulis Echinopsis Multiplicis 2-8 part.
3. a kind of Chinese herbal medicine buccal tablet for the treatment of oral ulcer according to claim 1 is characterized in that, is to be made by following weight portion raw material:
17 parts of Membrana Follicularis ovis, 17 parts of Calomelass, 17 parts of Plumbum preparatiums, 17 parts of Lithargyrums, 17 parts of Halloysitum Rubrums, 17 parts of Herba Menthaes, 15 parts of Herba Taraxacis, 15 parts in catechu, 15 parts of Flos Loniceraes, 15 parts of Momordica grosvenori roots, 15 parts of Mosla diantheras, 15 parts of Aloes, 10 parts of Herba Taxillis, 10 parts of fibroferritum, 10 parts of Radix Curcumaes, 10 parts of Radix Rhapontici, 10 parts of Fructus Pistaciae Veraies, 10 parts of Rhizoma Pleiones Yunnanensiss, 5 parts of Folium rosae multifloraes, 5 parts of the Radixs Astragali, 5 parts of Herba Anemones Hupehensiss, 5 parts of Herba Ophioglossis, 5 parts of Caulis Echinopsis Multipliciss.
4. according to any described a kind of Chinese herbal medicine buccal tablet for the treatment of oral ulcer among the claim 1-3, it is characterized in that preparation method:
(1) it is standby by formula proportion the decocting of two times of Membrana Follicularis ovis, Herba Menthae, Herba Taraxaci, catechu, Flos Lonicerae, Momordica grosvenori root, Mosla dianthera, Aloe, Herba Taxilli, Radix Curcumae, Radix Rhapontici, Fructus Pistaciae Verae, Rhizoma Pleiones Yunnanensis, Folium rosae multiflorae, the Radix Astragali, Anemone hupehensi, Herba Ophioglossi, Caulis Echinopsis Multiplicis to be boiled into medicinal liquid;
(2) it is standby by formula proportion Calomelas, Plumbum preparatium, Lithargyrum, Halloysitum Rubrum, fibroferritum to be crushed to 300-400 order fine powder;
(3) concentrating add pulverizing the standby fine powder in the back concentrator that stirs → pour into then in the standby medicinal liquid by formula proportion, namely obtaining the semi-finished product runny plaste, semi-finished product runny plaste → make tablet according to common film-making pressing process, can obtain finished product again.
CN 201210077003 2012-03-22 2012-03-22 Chinese herbal medicine buccal tablet for treating dental ulcer Expired - Fee Related CN102526643B (en)

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KR20190017873A (en) * 2016-06-08 2019-02-20 썬리겐 헬쓰케어 아게 Lipids having odd carbon atoms and their use as pharmaceutical compositions or nutritional supplements
CN108245534A (en) * 2018-03-17 2018-07-06 王伯 A kind of Chinese medicine for treating canker sore

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CN101297822B (en) * 2008-06-11 2010-11-17 丁昌荣 Ointment for curing mouth ulcer, children's aphthous ulcer and preparation method

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CN106620081A (en) * 2017-03-14 2017-05-10 四川香龙丹医药科技有限公司 Buccal tablet for treating oral ulcer

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