CN103860774B - It is a kind of for treating the Chinese medicine composition and preparation method of dysentery and hemorrhoid - Google Patents

It is a kind of for treating the Chinese medicine composition and preparation method of dysentery and hemorrhoid Download PDF

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CN103860774B
CN103860774B CN201410106095.5A CN201410106095A CN103860774B CN 103860774 B CN103860774 B CN 103860774B CN 201410106095 A CN201410106095 A CN 201410106095A CN 103860774 B CN103860774 B CN 103860774B
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hemorrhoid
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雷华亮
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Abstract

A kind of Chinese medicine composition that treating the diseases such as dysentery and hemorrhoid and preparation method, it is characterized in that having clearing heat and detoxicating, stop blooding anti-inflammatory, stop dysentery analgesic, gut purge defaecation, inducing diuresis and reducing edema, dispelling wind and removing obstruction in the meridians and other effects, matrix is prepared by excipient on the Chinese medicine composition and pharmacy meaning of following weight parts: radix scutellariae, thorn amaranth, Radix Angelicae Sinensis, Verbena officinalis, Long Stephania Herb, Eclipta prostrata, radix saposhnikoviae, dried immature fruit of citron orange etc..This invention the defaecation of Chinese medicine composition energy also can stop dysentery, bidirectional modulation.To intestines problems such as dysentery and hemorrhoid, it is general wide convenient to play the role of " Tong Yintongzhi " safety.At present with present invention treatment hemorrhoid 6, the age is 12 years old the smallest, and maximum 55 years old, wherein the course of disease is longest had 13 years, fully recovers;Treatment dysentery 22, most fast recovery from illness half a day, fully recovers for longest 3 days;Primary i.e. discharge is taken in treatment constipation 7.

Description

It is a kind of for treating the Chinese medicine composition and preparation method of dysentery and hemorrhoid
[technical field]
A kind of Chinese medicine composition for treating the diseases such as dysentery and hemorrhoid of this disclosure of the invention and preparation method, it is characterised in that have Clearing heat and detoxicating, stop blooding anti-inflammatory, stop dysentery analgesic, gut purge defaecation, inducing diuresis and reducing edema, dispelling wind and removing obstruction in the meridians and other effects.
[background technique]
Hemorrhoid are a kind of common diseases positioned at anus area, and any age can all fall ill, but with age, morbidity Rate gradually increases.In China, hemorrhoid are the most common anorectal diseases, are known as " ten male nine hemorrhoid ", the saying of " ten female, ten hemorrhoid ".About hemorrhoid The cause of disease there are mainly two types of theory.It is varicose vein theory first, it is believed that hemorrhoid are under distal rectal mucous membrane and under anal canal skin Veniplex extravasated blood, expansion and buckling are formed by venous mass.However well accepted theory is at present, under the anus pad of Thomson Move theory, it is believed that hemorrhoid are originally the normal anatomical structure in anal canal position, i.e. blood vessel pad, are the ring-types of dentate line and the above 1.5cm Cavernous transformation taeniae telarum.When only anus pad tissue is abnormal and is associated with symptom, hemorrhoid could be known as, just need to treat, treat mesh Be to release symptom, and non-elimination hemorrhoid body.
Clinical manifestation: hematochezia, the property of hematochezia can be painless, intermittent, blood after an action of the bowels, just when bleed or toilet paper on Band blood, constipation are drunk or are aggravated after feeding irritable food.The only falling inflation sense of pure internal piles without pain, can bleeding, be developed to de- It hangs down, pain just occurs when merging thrombosis, incarceration, infection.Internal piles is divided into 4 degree: 1. bleeding when I degree defecation, bleeding can after an action of the bowels Voluntarily stop, hemorrhoid do not deviate from anus;2. II degree often has hematochezia;Deviate from anus when defecation, is also received automatically after defecation;3. III degree Hand supplementary is needed also to receive after hemorrhoid abjection;IV degree hemorrhoid outside anus, cannot also be received for a long time;Wherein, II degree or more of internal piles multiform is at mixed Hemorrhoid are closed, the symptom for showing as internal piles and external piles exists simultaneously, and may occur in which pain discomfort, itch, and wherein itch is often since hemorrhoid are deviate from When toughness secretion flow out.Afterwards at mixed hemorrhoid more than three degree.External piles occurs to have when thrombus and inflammation swollen usually without characteristic symptom Swollen, pain.
Cause the etiology and pathogenesis multiterminal of hemorrhoid.As improper diet, raw and cold rich, moxibustion, sitting is stood long row long, so that internal organs are negative Sun imbalance, the corruption of intestines mansion is not normal, accumulates wet accumulated heat, inhibited defecation, because of damp invasion of lower energizer anal intestine, thermal burn yin collaterals, and the mad row of blood-head, then greatly Just blood is descended.Because local QI-blood circulation is unsmooth, and rectum is caused to swell and ache.Damp and hot inner product, taste disturbance in ascending and descending, heat are smoked in upper then dry mouth It is not each in bitter stomach, therefore appetite owed to shake.Internal organs are damp and hot not to dispel, and internal organs gas is unsmooth, and dry product of defecating is difficult to resolve, just when often descend blood.The disease of hemorrhoid Than that described above because of the interpretation of the cause, onset and process of an illness, also related with the exopathogens such as wind, dry, wet, hot.In addition chamber is excessive, or because of protracted dysentery and diarrhea, for a long time just It is secret, gestation production, abdominal tumor compressing etc..
The harm of hemorrhoid: one, hematochezia, bleed and serious spray blood all will lead to hypoferric anemia, or even infection.Two, It is overflowed outside anus because secretion increases, not only pollution clothes, also easily cause pain eczema, for female patient, will also will lead to one The breaking-out etc. of a little gynecological diseases.Three, constipation, dry feces are easy to squeeze and hurt haemorrhoids so that hematochezia, very pain when patient's Chang Yin defecation Hardship keeps stool more dry so bearing inconvenience by force, repeatedly, forms vicious circle.Four, hematochezia, pain and constipation is this Vicious circle makes one anorexia, causes the not normal and entire human body of spleen and stomach function to balance not normal and malnutritive, easily leads to liver Kidney diaseases, chronic colitis, anal fistula, intestinal cancer etc. occur.
Asymptomatic hemorrhoid are not required to treat;Symptomatic hemorrhoid are without radical cure;Based on non-operative treatment.Conservative therapy is invalid, Hemorrhoid abjection is serious, and the treatment such as larger fibrosis internal piles, injection is bad, merges anal fissure, anal fistula etc. and then needs operative treatment.From relatively gently The hemorrhoid development of symptom is needs operative treatment, often because not taking treatment, does not pay attention to adjusting daily life, leads to hemorrhoid Caused by recurrent exerbation.
Dysentery, under Gu claims intestines to ward off, is stagnant.For one of acute infectious intestinal disease.Clinic to generate heat, abdominal pain, it is tenesmus, stool Purulence blood is cardinal symptom.If infecting epidemic disease poison, sharply, with unexpected high fever, coma, convulsions person are fulminant dysentery for morbidity.Dysentery from the beginning of, Foreknowledge abdominal pain, then diarrhea, is day and night differed to tens of times for several times.Summer and autumn are mainly in, by damp and hot heresy, disorder of the spleen and stomach caused by internal damage is caused The dysfunction of the spleen in transport, stomach lose treatment for relieving indigestion and constipation, more hold under the arm stagnant, ferment enteron aisle and form.The described dysentery of Chinese medicine, had both been equal to the dysentery of modern medicine Disease also includes the intestines that amebic dysentery, ulcerative colitis, allergic colitis and some other enteric infection, poisoning etc. are led to The disease of the road development of evil in febrile disease, absorption function imbalance.
Modern medicine thinks that the pathogenesis of dysentery is mainly that bacterium, virus, fungi and helminth etc. cause, with colon or Terminal ileum purulent inflammation is major lesions.Keep intestinal mucosa impaired because generating inside and outside toxin after shigella dysenteriae invasion, lesion There is apocyte infiltration at position, forms abscess or ulcer.The lymphonodi mesenterici hyperemia enlargement of lesion part.Toxic bacillary dysentery is main Pathological change is that whole body parteriole vessel wall permeability increases, and makes vascular wall surrounding tissue Severe edema, internal organs (such as brain, Liver, kidney and adrenal gland etc.) there is oedema.When people's resistance reduces, shigella dysenteriae enters small intestine mass propagation through stomach, some are dead The bacterium died releases endotoxin, and stimulation intestinal wall increases its permeability.It is absorbed into the toxin of blood flow, it finally can be from colon Mucous membrane discharge, makes adaptive colitis and to cause mucosal injury, and on this basis, shigella dysenteriae and enteron aisle other bacteriums are in mucomembranous surface With bred under mucous membrane, further generate destruction, cause inflammatory reaction.The initial stage of morbidity, the endotoxin of shigella dysenteriae secretion With inflammatory stimulus intestinal wall nerve endings, and cause intestinal tube spasm, enterocinesia increase, intestinal wall absorb moisture reduce and intestinal wall blood vessel Slurries exudation, and there is diarrhea;Hereafter, intestinal mucosa diffusivity congestion and edema, a large amount of neutrophil infiltrations, with a large amount of mucus And cellulose exudation, ulcer, bleeding are eventually formed, mucopurulent bloody stool just occurs.
Hemorrhoid and dysentery are both intestines problem, and most dysentery (except cold of insufficiency type dysentery) and hemorrhoid are because wind, dry, wet, hot etc. are outer It is evil related, can " Tong Yintongzhi ", however hemorrhoid can be treated simultaneously at present and the drug of dysentery is seldom, in majority treatment hemorrhoid Medicine is taken under causing to rush down.This invention the defaecation of Chinese medicine composition energy also can stop dysentery, bidirectional modulation, " Tong Yintongzhi " is used for Dysentery, enteritis, taste-blindness rate bleeding, hemorrhoid gall, hemorrhoidal hemorrhage, constipation, the general wide convenience of safety.
[summary of the invention]
A kind of Chinese medicine composition for treating the diseases such as dysentery and hemorrhoid of this disclosure of the invention and preparation method.
Purpose of this invention is disclose a kind of Chinese medicine composition for treating the diseases such as dysentery and hemorrhoid and preparation method, spy Sign is there is clearing heat and detoxicating, stop blooding anti-inflammatory, stop dysentery analgesic, gut purge defaecation, inducing diuresis and reducing edema, dispelling wind and removing obstruction in the meridians and other effects, is used for dysentery Disease, enteritis, taste-blindness rate bleeding, hemorrhoid gall, hemorrhoidal hemorrhage, constipation, matrix is by following Chinese medicine compositions and pharmacy Dosage form is assigned in meaning to be prepared:
Radix scutellariae pierces the amaranth Radix Angelicae Sinensis Verbena officinalis Long Stephania Herb Eclipta prostrata radix saposhnikoviae dried immature fruit of citron orange.
Present composition pharmacology are as follows:
Radix scutellariae: bitter is cold in nature, enters lung, the heart, gallbladder, large intestine channel, there is the function of heat-clearing and damp-drying drug, purging fire for removing toxin, miscarriage prevention, to heat temperature Vomiting uncomfortable in chest, cough with lung heat, blood-heat bleeding, hyperpyrexia polydipsia, damp-heat diarrhea etc. have good effects." Bencao Jingshu ": radix scutellariae, property Clear respectful, so evil removing: bitter is so eliminating dampness;Cold sensation of the genitalia is so victory is hot, therefore leads all heat.All hot persons, heat symptoms caused by an exopathgen and time heat, jaundice, intestines It is out-of-the-way, let out dysentery, the disease of all damp and hot victory analyses it, then all diseases are from recover.Bitter cold can be except damp and hot, so small intestine benefit and water are from by source It is clear then flow clean.Modern study test radix scutellariae to shigella dysenteriae, typhoid bacillus, paratyphosum Bacterium, comma bacillus, Escherichia coli, Proteus, Pseudomonas aeruginosa, staphylococcus, hemolytic vessel used to hold grain at the imperial sacrifice coccus (a, B), Diplococcus pneumopniae, corynebacterium diphtheriae etc. have inhibiting effect.
Pierce amaranth: slightly sweet flavor, slight bitter are puckery, cool in nature.Enter lung, liver, large intestine channel, clearing heat and promoting diuresis, removing toxicity for detumescence, cooling blood and hemostasis.With In dysentery, enteritis, taste-blindness rate bleeding, hemorrhoid gall, hemorrhoidal hemorrhage, Thyroid Gland Swell, cholecystitis, gall stone, Constipation, infant fetal toxin;Venomous snake bite, skin eczema, furuncle purulence ulcer are controlled in external application.
Radix Angelicae Sinensis: sweet in flavor, pungent, bitter;It is warm-natured.Return liver, the heart, the spleen channel.It enriches blood;Promoting blood circulation;Menstruction regulating and pain relieving;Moisturizing dryness and lubricating intestine.Cure mainly blood Empty all cards;Irregular menstruation;Menostasis;Dysmenorrhea;Abdominal mass knot is poly-;Metrorrhagia and metrostaxis;Asthenia cold abdominalgia;Flaccidity syndrome and arthralgia syndrome;Numbness;Intestines are dry and shit is difficult;Dysentery with bloody stool After weigh;Ulcer sores;Injury from falling down.Modern research shows that Radix Angelicae Sinensis is to external dysentery, typhoid fever, paratyphoid, Escherichia coli, diphtheria bar Bacterium, comma bacillus and a, B hemolytic streptococcus etc. have antibacterial action.Mouse capillary permeability can be reduced.External application can add Fast rabbit ear wound healing, makes contrafluxion, leucocyte and fiber infiltration, and newborn epithelium regeneration has hemostasis to local organization and adds Strong peripheral circulation effect.Illustrate that Radix Angelicae Sinensis has antibacterial, antiinflammation.
Verbena officinalis: bitter, it is cool in nature.Return liver, the spleen channel.It is clearing heat and detoxicating;Blood circulation;Inducing diuresis for removing edema;Preventing malaria;For abdominal mass product It is poly-, amenorrhea and algomenorrhea, acute gastroenteritis, bacillary dysentery, hepatitis, ephritis, oedema, urinary tract infections, hemorrhoid etc..
Long Stephania Herb: it is puckery, hardship, cold in nature, enter spleen kidney channel.With clearing heat and detoxicating, dampness removing, detumescence, defaecation, dispelling wind and removing obstruction in the meridians, go The effect of product analgesic.The major functions: diarrhea, acute nephritis, bacillary dysentery, mazoitis, ulcerative carbuncle redness, rheumatic arthritis, sciatica, hernia Gas, finger sore, traumatic injury, controls pyreticosis and goes mad difficult urination, jaundice, gastroenteritis, dysentery, constipation, hematuria, gonorrhoea, and sore carbuncle is swollen Poison, can myogenic hemostasis.
Eclipta prostrata: it is sweet in flavor, sour, it is cold in nature.Return liver and kidney channel.It is nourishing liver and kidney, cooling blood and hemostasis.Modern study this product, which has, to be improved Body non-specific immune function eliminates oxygen radical to inhibit 5- lipoxygenase, protects chromosome, and liver protection promotes liver cell Regeneration increases coronary flow, extends life of the mouse under normobaric hypoxia, improves depositing in hypobaric hypoxia mouse Motility rate, and have calmness, ease pain, promote hair growth, make the effects of hair blackening, hemostasis, antibacterial, anti-Amoeba, anticancer.
Radix saposhnikoviae: acrid flavour;It is sweet;Slightly warm in nature.Return bladder meridian;Lung channel;The spleen channel;Liver Channel.Can expel pathogenic wind from the body surface, expel endogenous wind to relieve convulsion, spasmolysis, It is antipruritic.The major functions: affection of exogenous wind-cold;Headache bodily pain;Rheumatic arthralgia;Skeletal pain;Abdominal pain diarrhoea;Discharging fresh blood stool;Tetanus;Rubeola scabies Itch;Sore from the beginning of.
The dried immature fruit of citron orange: bitterly;It is cold in nature.Returns spleen;Stomach;Liver;The heart;Large intestine channel.The major functions: internal stagnation;Feeling of fullness distending pain;Big constipation Knot;Weight after rush down dysentery;Accumulation of pathogens in chest;Gastroptosis;Uterine prolapse;Rectal prolapse.
With present invention treatment hemorrhoid 6, the age is 12 years old the smallest, and maximum 55 years old, wherein the course of disease is longest 13 years, Recovery from illness;Treatment dysentery 22, most fast recovery from illness half a day, fully recovers for longest 3 days;Primary i.e. discharge is taken in treatment constipation 7.
The preparation method and step of the present composition are as follows:
Preparation method one:
Each Ingredient Wt ratio are as follows: 1-2 parts of radix scutellariae, thorn amaranth 2-4 parts, 1-2 parts of Radix Angelicae Sinensis, 1-3 parts of Verbena officinalis, 1-3 parts of Long Stephania Herb, 2-4 parts of Eclipta prostrata, 1-2 parts of radix saposhnikoviae, 1-2 parts of the dried immature fruit of citron orange.
Above-mentioned raw materials are rinsed into airing, is dried in vacuo, is crushed and screened into fine powder, mixes, is made with suitable auxiliary material Various dosage forms in pharmacy meaning.
Preparation method two:
Each Ingredient Wt ratio are as follows:
50-200 parts of radix scutellariae, amaranth 150-800 parts of thorn, 60-300 parts of Radix Angelicae Sinensis, 150-500 parts of Verbena officinalis, Long Stephania Herb 150-600 Part, it is 100-800 parts of Eclipta prostrata, 50-200 parts windproof, 50-200 parts of the dried immature fruit of citron orange.
(1) after Radix Angelicae Sinensis, radix saposhnikoviae, the dried immature fruit of citron orange being extracted volatile oil using the method for water distillation, with radix scutellariae, thorn amaranth, Verbena officinalis, excrement Sincere, Eclipta prostrata of dustpan etc. decoct using water or be extracted with alcohol reflux, and after extracting solution is condensed into liquid extract, volatilization is added Oil mixes with suitable auxiliary material, various dosage forms in pharmacy meaning is made;
(2) by radix scutellariae, thorn amaranth, Radix Angelicae Sinensis, Verbena officinalis, Long Stephania Herb, Eclipta prostrata, radix saposhnikoviae, eight taste medicinal material of the dried immature fruit of citron orange first use water into Row decocts, and is collected simultaneously volatile oil, then filters, eight taste medicinal materials are extracted with alcohol reflux, and extracting solution merging is condensed into stream After medicinal extract, volatile oil is added, is mixed with suitable auxiliary material, various dosage forms in pharmacy meaning is made;
(3) by the part medicine in radix scutellariae, thorn amaranth, Radix Angelicae Sinensis, Verbena officinalis, Long Stephania Herb, Eclipta prostrata, radix saposhnikoviae, eight taste medicinal material of the dried immature fruit of citron orange Material is ground into fine powder, and remaining medicinal material decoct or extracted with alcohol reflux using water, after extracting solution is condensed into liquid extract, It is mixed with fine powder and appropriate auxiliary material, various dosage forms in pharmacy meaning is made;
(4) by the part medicine in radix scutellariae, thorn amaranth, Radix Angelicae Sinensis, Verbena officinalis, Long Stephania Herb, Eclipta prostrata, radix saposhnikoviae, eight taste medicinal material of the dried immature fruit of citron orange Material is ground into fine powder, after remaining Radix Angelicae Sinensis, radix saposhnikoviae, the dried immature fruit of citron orange extract volatile oil using the method for water distillation, with remaining radix scutellariae, thorn The medicinal materials such as amaranth, Verbena officinalis, Long Stephania Herb, Eclipta prostrata decoct or extracted with alcohol reflux using water, and extracting solution is condensed into stream After medicinal extract, volatile oil is added, is mixed with fine powder and appropriate auxiliary material, various dosage forms in pharmacy meaning is made.
It in above-mentioned preparation method, is decocted if it is with water, the water of 4~10 times of weight is added, decocted 0.5 hour~3 hours, It decocts 1~4 time, the water of 8 times of amounts is preferably added, decoct 1 hour, decoct 3 times;It is extracted if it is with alcohol reflux, addition 4~ 12 times amount ethyl alcohol, refluxing extraction 0.5~3 hour, extract 1~4 time, preferably be added 10 times amount ethyl alcohol (concentration 50%~ 70%) it extracts 3 times, every time 1 hour;If it is first being decocted with water, after extracted with alcohol reflux, the water of 8 times of amounts are preferably added, It decocts 1 hour, decocts 2 times, the ethyl alcohol (concentration 50%~70%) that 10 times of amounts are then added extracts 2 times, every time 1 hour.Radix Angelicae Sinensis, Radix saposhnikoviae, the dried immature fruit of citron orange are using the method for water distillating extracting oil: medicinal material being placed in the container of sealing, 4~10 times of weight are added Water connects reflux unit, decocts or distills 2~4 hours, is collected simultaneously volatile oil.The volatile oil being collected into can also be carried out Beta-cyclodextrin inclusion compound keeps it more stable, convenient for being added in powder or particle.
It is the application in order to reduce auxiliary material, also for medicine by part pulverizing medicinal materials at fine powder in above-mentioned preparation method Effect, the medicinal material of crushing can be all or part of single medicinal material, be also possible to a part of a few taste medicines.
In above-mentioned preparation method, the excipient substance of addition can be starch, honey, sucrose, magnesium stearate, sorbierite, micro- One of crystal fiber, superfine silica gel powder, sodium carboxymethyl starch, lactose or more than one combination.Do not violating the design spirit In the case where, the drug that can also be added has: honeysuckle, Fructus Forsythiae, Radix Isatidis, cordate houttuynia, purslane, the Chinese bulbul, native dalbergia wood, three Seven, glutinous rehmannia, rheum officinale, sophora flower, fructus cannabis, Poria cocos, the coptis, lalang grass rhizome, Asiatic plantain, cacumen biotae, garden burnet, the Fructus Sophorae, setose thistle, field thistle, Pu It is Huang, hairyvein agrimony, bigleafbeautyberry root or leaf, radix aucklandiae, acalypha copperleaf, schizonepeta, Japanese Stephania Root, donkey-hide gelatin, dandelion, viola mandshurica, Cortex Magnoliae Officinalis, peppermint, white Art, rhizoma alismatis, semen coicis, wrinkled giant hyssop etc., one such or more than one combination.
Medicine preparation of the invention is preferably capsule, tablet, granule, oral solutions, and any dosage form can also be made, Such as: powder, pill, paste, mixture, syrup, injection, posts agent, liniment, suppository.It is prepared by said medicine combination When medicament, as needed, can be added it is other, such as: flavoring agent, solubilizer, suspension, dilution, disintegrating agent, lubricant.Packet Clothing can be sugar-coat, film-coating, enteric coating etc..
Pharmacodynamic test of the invention shows:
Anastalsis of the invention: experiment shows that anastalsis is obvious, can be obviously shortened bleeding time and the bleeding of rat Amount.With negative control group ratio, the bleeding time shortens 1.2 times, 1 times fewer than negative control group of amount of bleeding or more;With " peaceful Huimin and Agent office side " " fructus sophorae compound pill " side, in (Isodose, same dosage form, same processing method) comparative test, the present composition is excellent In " fructus sophorae compound pill " side, the bleeding time is obviously shortened, and amount of bleeding is obviously few, wherein in median dose comparison, the bleeding time is short 40%.
Anti-infectious function of the invention: experiment shows that anti-infectious function is obvious.Rat wound infection model, rat are bacillary On dysentery model, big, middle dosage be substantially better than " formulary of peaceful benevolent dispensary " " fructus sophorae compound pill " side (Isodose, same dosage form, together The processing method of sample), speed of wound healing is obviously fast.
Analgesic effect of the invention: experiment shows the analgesic effect for having certain.On the trauma model of rat tail, hence it is evident that excellent In negative control group.
Anti-inflammatory effect of the invention: experiment shows that the present invention has anti-inflammatory effect.Mouse ear caused by dimethylbenzene can be inhibited swollen Expansibility can reduce Mouse Acetic Acid and cause scorching capillary permeability.
Gut purge defecating feces excretion of the invention: normal person takes this product, and defecation frequency increases, and formed stools are normal, excrement table Face is glossy glossy.Constipation person takes this product, takes half an hour after i.e. defecation.
[specific embodiment]
Following specific embodiments are detailed description of the invention, should not be understood as limitation of the present invention.
Embodiment 1:
100 grams of radix scutellariae, 200 grams of amaranth are pierced, 100 grams of Radix Angelicae Sinensis, 100 grams of Verbena officinalis, 100 grams of Long Stephania Herb, 200 grams of Eclipta prostrata, is prevented 100 grams of wind, 100 grams of the dried immature fruit of citron orange, above-mentioned raw materials are rinsed into airing, is dried in vacuo, crushed 60 meshes, at fine powder, are mixed, every 100 Gram powder adds refined honey 120-150 to restrain into honeyed bolus, 10 grams of every ball.
Embodiment 2:
200 grams of radix scutellariae, 500 grams of amaranth are pierced, 200 grams of Radix Angelicae Sinensis, 200 grams of Verbena officinalis, 200 grams of Long Stephania Herb, 500 grams of Eclipta prostrata, is prevented 200 grams of wind, 200 grams of the dried immature fruit of citron orange, after Radix Angelicae Sinensis, radix saposhnikoviae, the dried immature fruit of citron orange are extracted volatile oil using the method for water distillation, with radix scutellariae, thorn amaranth, horse The mixing such as whip grass, Long Stephania Herb, Eclipta prostrata, is added 22 liters of water, decocts 1 hour, decocts 3 times, after extracting solution is condensed into liquid extract, It is mixed with suitable Icing Sugar, granulation, drying spray into volatile oil, seal 12 hours, drug granule is made.
Embodiment 3:
250 grams of radix scutellariae, 500 grams of amaranth are pierced, 250 grams of Radix Angelicae Sinensis, 300 grams of Verbena officinalis, 300 grams of Long Stephania Herb, 500 grams of Eclipta prostrata, is prevented 250 grams of wind, 250 grams of the dried immature fruit of citron orange, the container of sealing is added together, connects reflux unit for 20 liters of water, decocts, and it is small to extract volatile oil 2 When, extracting solution is filtered out, 22 liters of ethyl alcohol that concentration is 60% are then added, refluxing extraction 1 hour, extracts 2 times, extracting solution is recycled After alcohol, extracting solution is condensed into liquid extract, mixes with suitable starch, dry, sprays into volatile oil, seals 12 hours, is distributed into Capsule.
Embodiment 4:
200 grams of radix scutellariae, 300 grams of amaranth are pierced, 300 grams of Radix Angelicae Sinensis, 300 grams of Verbena officinalis, 300 grams of Long Stephania Herb, 300 grams of Eclipta prostrata, is prevented 200 grams of wind, 200 grams of the dried immature fruit of citron orange, thorn amaranth therein, each 100 grams of Radix Angelicae Sinensis are ground into fine powder, remaining medicinal material is put into the appearance of sealing 20 liters of ethyl alcohol of 50% concentration are added in device, extract 1 hour, extract 3 times, combined extract, recycle ethyl alcohol, and extracting solution is condensed into Liquid extract is mixed with fine powder, dry, and partial pressure in flakes, is coated, every 0.5 gram.
Embodiment 5:
250 grams of radix scutellariae, 250 grams of amaranth are pierced, 250 grams of Radix Angelicae Sinensis, 250 grams of Verbena officinalis, 250 grams of Long Stephania Herb, 250 grams of Eclipta prostrata, is prevented 250 grams of wind, 250 grams of the dried immature fruit of citron orange, thorn amaranth therein, Eclipta prostrata, Radix Angelicae Sinensis, each 50 grams of the dried immature fruit of citron orange are ground into fine powder, remaining Radix Angelicae Sinensis is prevented After wind, the dried immature fruit of citron orange extract volatile oil using the method for steam distillation, it is incorporated to remaining radix scutellariae, thorn amaranth, Verbena officinalis, Long Stephania Herb, drought The medicinal materials such as lotus grass, are placed in the container of sealing, are added 20 liters of ethyl alcohol that concentration is 70%, refluxing extraction 1 hour, extract 2 times, then It is decocted, 1 hour every time, is decocted 2 times with 20 liters of water, after extracting solution is recycled ethyl alcohol, be condensed into liquid extract together, liquid extract and thin Powder mixes, dry, sprays into volatile oil, seals 12 hours, is distributed into capsule.
Typical case:
Treat constipation case:
Ms Lu, female, 80 years old, readme suffered from habitual constipation 3 years, and often 3~4 talent stool are primary, just when dry feces, It can not make great efforts, have no alternative but, oneself gone to pluck out dry dung with hand, it is very worried, it does not defecate within 4 days now, has awareness of defecation, but squatted very It also can not pull long.Water decoction of the present invention is taken, after half an hour, awareness of defecation is strong, and dry dung is discharged at once, feels light immediately.
Treat hemorrhoid case:
Thunder, male, 55 years old, peasant, readme suffered from hemorrhoid for many years, and intermittent attack, when stool drips a small amount of blood, swollen with anus Bitterly, the past all can voluntarily improve, so not treating, hematochezia is more within the next few days, just when anus intumescence abjection and distending pain, abdomen have A little pain.This product is taken, abdominal pain disappears, and second day, there was a small amount of bloodstain on stopping of bleeding of defecating, stool surface, and anus abdominal pain is not Obviously, continue to take this product 5 days, not reaccess within 1 year.
Lee, female, 46 years old, peasant, readme suffered from hemorrhoid for many years, intermittent attack, and nearly breaking-out aggravates.Blood is penetrated when now defecating, Bleed, color is scarlet, feel not to the utmost with inhibited defecation, just when anus in intumescence abjection, need to hand rest return anus in.Take this product one It 3~5 times, while being smoked with this product warm aqua hip bath and washing anus, one day 2~3 times.Take this product second day, hematochezia amount is obvious It reduces.Hip bath smokes wash anus three days after, intumescence is no longer deviate from.After continuously taking this product 15 days, recovery from illness.
Treat dysentery case:
Huang, male, 25 years old, diarrhea.Readme this two days is celebrating, eats greasy, and raw food is miscellaneous.This morning diarrhea, tenesmus, excrement Just stench is just felt not to the utmost, has loose bowels once every half an hour.With abdominal distension, no appetite.Noon takes this product water decoction, goes to side at once Institute, feels emptying immediately, and abdominal distension also disappears.Take this product afternoon again, evening defecation is normally accused and is cured.
Mr. Wang, male, 6 years old, 38 degree of body temperature, early top faintishness, thirsty, watery diarrhea was tenesmus, and or so each hour draws Once, noon draws the light violet purulence blood of a small amount of egg white sample.Noon takes this product, and afternoon, temperature recovery was normal, and stool colour is normal, row Bowel frequency number is obviously reduced with rear double infection, but excrement or blocky and water sample are miscellaneous.This product is taken, three times a day, the next afternoon accuses More, continue to take one day.
Without departing from the spirit of the design of the present invention, ordinary people in the field carries out technical solution of the present invention each Kind becomes row and improves, and should fall within the scope of protection defined by the claims of the present invention.

Claims (4)

1. a kind of Chinese medicine composition for treating dysentery and hemorrhoid, it is characterised in that have clearing heat and detoxicating, anti-inflammatory, stop dysentery of stopping blooding to stop Bitterly, gut purge defaecation, inducing diuresis and reducing edema, dispelling wind and removing obstruction in the meridians effect, be used for dysentery, enteritis, taste-blindness rate bleeding, hemorrhoid gall, Hemorrhoidal hemorrhage, constipation, matrix are prepared by assigning dosage form on following Chinese medicine compositions and pharmacy meaning: 50-200 parts of radix scutellariae, thorn 150-800 parts of amaranth, 60-300 parts of Radix Angelicae Sinensis, 150-500 parts of Verbena officinalis, 150-600 parts of Long Stephania Herb, 100-800 parts of Eclipta prostrata, radix saposhnikoviae 50-200 parts, 50-200 parts of the dried immature fruit of citron orange.
2. Chinese medicine composition according to claim 1, it is characterised in that each weight ratio of constituents are as follows: 1-2 parts of radix scutellariae, thorn amaranth 2- 4 parts, 1-2 parts of Radix Angelicae Sinensis, 1-3 parts of Verbena officinalis, 1-3 parts of Long Stephania Herb, 2-4 parts of Eclipta prostrata, 1-2 parts of radix saposhnikoviae, 1-2 parts of the dried immature fruit of citron orange.
3. Chinese medicine composition according to claim 1, it is characterised in that each weight ratio of constituents are as follows: 250 parts of radix scutellariae, thorn amaranth 250 parts, 250 parts of Radix Angelicae Sinensis, 250 parts of Verbena officinalis, 250 parts of Long Stephania Herb, 250 parts of Eclipta prostrata, 250 parts, 250 parts of the dried immature fruit of citron orange of radix saposhnikoviae.
4. Chinese medicine composition according to claim 1, it is characterised in that each weight ratio of constituents are as follows: 200 parts of radix scutellariae, thorn amaranth 300 parts, 300 parts of Radix Angelicae Sinensis, 300 parts of Verbena officinalis, 300 parts of Long Stephania Herb, 300 parts of Eclipta prostrata, 200 parts, 200 parts of the dried immature fruit of citron orange of radix saposhnikoviae.
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CN105106749A (en) * 2015-09-02 2015-12-02 江淑芬 Traditional Chinese medicinal composition for haemorrhoids treatment in general surgery departments
CN105362735A (en) * 2015-11-08 2016-03-02 薛学明 Medicine for treating hemorrhoids and preparation method of medicine
CN106109768A (en) * 2016-08-08 2016-11-16 孙爱荣 A kind of Chinese medicine composition treating hemorrhoid
CN107184611A (en) * 2017-04-20 2017-09-22 李锦英 Outer coating of a kind of hemorrhoid and preparation method thereof
CN109718317B (en) * 2019-03-05 2023-12-12 上海中医药大学附属曙光医院 Traditional Chinese medicine composition for treating ulcerative colitis
CN113288936B (en) * 2021-06-28 2022-08-16 佛山科学技术学院 Pharmaceutical composition for treating ulcerative colitis and application thereof
CN115089659A (en) * 2022-06-02 2022-09-23 广西纯正堂制药有限公司 Traditional Chinese medicine composition and preparation method and application thereof

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