CN103814139B - 用于检测无细胞的病原体特异性核酸的方法和试剂盒 - Google Patents
用于检测无细胞的病原体特异性核酸的方法和试剂盒 Download PDFInfo
- Publication number
- CN103814139B CN103814139B CN201280026842.3A CN201280026842A CN103814139B CN 103814139 B CN103814139 B CN 103814139B CN 201280026842 A CN201280026842 A CN 201280026842A CN 103814139 B CN103814139 B CN 103814139B
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- nucleic acid
- mycobacterium tuberculosis
- tuberculosis
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811203829.6A CN109280713A (zh) | 2011-04-01 | 2012-04-02 | 用于检测无细胞的病原体特异性核酸的方法和试剂盒 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161470774P | 2011-04-01 | 2011-04-01 | |
| US61/470,774 | 2011-04-01 | ||
| PCT/US2012/031814 WO2012135815A2 (en) | 2011-04-01 | 2012-04-02 | Methods and kits for detecting cell-free pathogen-specific nucleic acids |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811203829.6A Division CN109280713A (zh) | 2011-04-01 | 2012-04-02 | 用于检测无细胞的病原体特异性核酸的方法和试剂盒 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103814139A CN103814139A (zh) | 2014-05-21 |
| CN103814139B true CN103814139B (zh) | 2018-11-13 |
Family
ID=46932429
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201280026842.3A Expired - Fee Related CN103814139B (zh) | 2011-04-01 | 2012-04-02 | 用于检测无细胞的病原体特异性核酸的方法和试剂盒 |
| CN201811203829.6A Pending CN109280713A (zh) | 2011-04-01 | 2012-04-02 | 用于检测无细胞的病原体特异性核酸的方法和试剂盒 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811203829.6A Pending CN109280713A (zh) | 2011-04-01 | 2012-04-02 | 用于检测无细胞的病原体特异性核酸的方法和试剂盒 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20140147851A1 (enExample) |
| EP (1) | EP2694680A4 (enExample) |
| JP (2) | JP6430826B2 (enExample) |
| CN (2) | CN103814139B (enExample) |
| AU (3) | AU2012236109A1 (enExample) |
| RU (1) | RU2644672C2 (enExample) |
| WO (1) | WO2012135815A2 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2012236109A1 (en) * | 2011-04-01 | 2013-11-21 | Occam Biolabs, Inc. | Methods and kits for detecting cell-free pathogen-specific nucleic acids |
| EP3174106A1 (en) * | 2011-09-30 | 2017-05-31 | Intel Corporation | Tungsten gates for non-planar transistors |
| ES2716114T3 (es) | 2013-05-24 | 2019-06-10 | Occam Biolabs Inc | Sistema y procedimiento para recoger una muestra de ácido nucleico |
| US9644232B2 (en) * | 2013-07-26 | 2017-05-09 | General Electric Company | Method and device for collection and amplification of circulating nucleic acids |
| KR20240038168A (ko) | 2013-11-07 | 2024-03-22 | 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 | 인간 마이크로바이옴 및 그의 성분의 분석을 위한 무세포 핵산 |
| CN104894226A (zh) * | 2014-03-07 | 2015-09-09 | 复旦大学 | 检测实验室结核分枝杆菌微环境表面污染的方法及其检测试剂盒 |
| US10287570B2 (en) | 2014-11-21 | 2019-05-14 | Occam Biolabs, Inc. | System and method for collecting a sample of nucleic acid |
| EP4450636A3 (en) | 2015-05-18 | 2025-01-01 | Karius, Inc. | Compositions and methods for enriching populations of nucleic acids |
| ES2912965T3 (es) | 2015-09-09 | 2022-05-30 | Drawbridge Health Inc | Dispositivos para la recopilación, estabilización y conservación de muestras |
| EP3141612A1 (en) * | 2015-09-10 | 2017-03-15 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Method and device for nucleic acid based diagnostic approaches including the determination of a deviant condtion, especially a health condition and/or pathogenic condition of a sample |
| WO2017077999A1 (ja) * | 2015-11-06 | 2017-05-11 | 公立大学法人横浜市立大学 | 結核菌群由来dnaの検出方法 |
| CN105296661A (zh) * | 2015-12-02 | 2016-02-03 | 北京市结核病胸部肿瘤研究所 | 通过检测游离核酸诊断结核病的试剂盒及其应用 |
| CN116987777A (zh) | 2016-03-25 | 2023-11-03 | 凯锐思公司 | 合成核酸掺入物 |
| WO2018008083A1 (ja) * | 2016-07-05 | 2018-01-11 | 株式会社日立製作所 | Dna検出方法およびそのための装置 |
| KR102489902B1 (ko) | 2016-11-11 | 2023-01-19 | 바이오 래드 래버러토리스 인코오포레이티드 | 핵산 샘플을 프로세싱하는 방법 |
| EP3573756A1 (en) * | 2017-01-30 | 2019-12-04 | Safeguard Biosystems Holdings Ltd. | Bead beating tube and method for extracting deoxyribonucleic acid and/or ribonucleic acid from microorganisms |
| EP3610034B1 (en) | 2017-04-12 | 2022-06-08 | Karius, Inc. | Sample preparation methods, systems and compositions |
| CN108165561B (zh) * | 2017-12-01 | 2021-06-18 | 北京蛋白质组研究中心 | 结核分枝杆菌H37Rv编码基因及其应用 |
| CN108165560B (zh) * | 2017-12-01 | 2021-06-08 | 北京蛋白质组研究中心 | 结核分枝杆菌H37Rv编码基因及其应用 |
| CN108165563B (zh) * | 2017-12-01 | 2021-02-19 | 北京蛋白质组研究中心 | 结核分枝杆菌H37Rv编码基因及其应用 |
| CN108165562B (zh) * | 2017-12-01 | 2021-06-08 | 北京蛋白质组研究中心 | 结核分枝杆菌H37Rv编码基因及其应用 |
| CA3082601A1 (en) | 2018-03-16 | 2019-09-19 | Karius, Inc. | Sample series to differentiate target nucleic acids from contaminant nucleic acids |
| CA3118990A1 (en) | 2018-11-21 | 2020-05-28 | Karius, Inc. | Direct-to-library methods, systems, and compositions |
| CN111876411A (zh) * | 2019-09-06 | 2020-11-03 | 深圳微伴生物有限公司 | 获得cfDNA标准品的引物组、PCR扩增阳性标准品及其制备方法、试剂盒及应用 |
| KR102286570B1 (ko) * | 2019-11-19 | 2021-08-05 | 대한민국 | 소변 시료를 이용하여 결핵 진단용 프라이머, 프로브, 키트 및 이들의 용도 |
| CN114480691A (zh) * | 2022-01-24 | 2022-05-13 | 广州迪澳基因科技有限公司 | 基于熔解曲线检测结核分枝杆菌复合菌群的方法及试剂盒 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1312723A (zh) * | 1998-02-18 | 2001-09-12 | 考丽克萨有限公司 | 诊断结核病的化合物和方法 |
| CN1388378A (zh) * | 2002-06-17 | 2003-01-01 | 四川大学 | 结核分枝杆菌诊断检测试剂 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69230305T2 (de) * | 1991-08-15 | 2000-07-20 | F. Hoffmann-La Roche Ag, Basel | Primerpaar zum Nachweis von Mycobacterium |
| DK0975807T3 (da) * | 1997-05-02 | 2007-01-29 | Gen Probe Inc | To-trins hybridisering og indfangning af et polynukleotid |
| DE19752898A1 (de) * | 1997-11-28 | 1999-08-05 | Centeon Pharma Gmbh | Verfahren zum Nachweis hoher Vierenkonzentrationen im Blutplasma und/oder Blutserum mittels der Polymerasekettenreaktion |
| US6951722B2 (en) * | 1999-03-19 | 2005-10-04 | Takara Bio Inc. | Method for amplifying nucleic acid sequence |
| TWI237695B (en) * | 1999-12-14 | 2005-08-11 | Joy Biomedical Corp | Helicobacter pylori antigens in blood |
| EP1315814A2 (en) * | 2000-07-24 | 2003-06-04 | Inpharmatica Limited | Adhesion molecules |
| CA2555081A1 (en) * | 2004-02-03 | 2005-08-18 | Postech Foundation | High throughput device for performing continuous-flow reactions |
| AU2006214444B8 (en) * | 2005-02-17 | 2012-04-05 | Trovagene, Inc. | Compositions and methods for detecting pathogen specific nucleic acids in urine |
| ATE474066T1 (de) * | 2005-11-15 | 2010-07-15 | Genoid Kft | Verfahren zum nachweis von pathogenen mittels molecular beacons |
| US8741565B2 (en) * | 2005-12-30 | 2014-06-03 | Honeywell International Inc. | Oligonucleotide microarray for identification of pathogens |
| US20090142757A1 (en) * | 2007-11-30 | 2009-06-04 | Asiagen Corporation | Strip and method for detecting nucleotide amplification products of mycobacterium tuberculosis and non-tuberculous mycobacterium |
| US8029806B2 (en) * | 2008-04-16 | 2011-10-04 | Asiagen Corporation | Method for diagnosing of Mycobacterium tuberculosis |
| WO2010080691A1 (en) * | 2009-01-06 | 2010-07-15 | Qimin You | Cross priming amplification of target nucleic acids |
| AU2012236109A1 (en) * | 2011-04-01 | 2013-11-21 | Occam Biolabs, Inc. | Methods and kits for detecting cell-free pathogen-specific nucleic acids |
-
2012
- 2012-04-02 AU AU2012236109A patent/AU2012236109A1/en not_active Abandoned
- 2012-04-02 US US14/009,199 patent/US20140147851A1/en not_active Abandoned
- 2012-04-02 WO PCT/US2012/031814 patent/WO2012135815A2/en not_active Ceased
- 2012-04-02 JP JP2014502902A patent/JP6430826B2/ja not_active Expired - Fee Related
- 2012-04-02 CN CN201280026842.3A patent/CN103814139B/zh not_active Expired - Fee Related
- 2012-04-02 EP EP12765867.2A patent/EP2694680A4/en not_active Withdrawn
- 2012-04-02 CN CN201811203829.6A patent/CN109280713A/zh active Pending
- 2012-04-02 RU RU2013148806A patent/RU2644672C2/ru not_active IP Right Cessation
-
2017
- 2017-05-09 AU AU2017203071A patent/AU2017203071A1/en not_active Abandoned
- 2017-07-31 US US15/664,074 patent/US20170369932A1/en not_active Abandoned
-
2018
- 2018-05-10 JP JP2018091537A patent/JP2018117645A/ja active Pending
-
2019
- 2019-07-05 AU AU2019204844A patent/AU2019204844A1/en not_active Abandoned
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1312723A (zh) * | 1998-02-18 | 2001-09-12 | 考丽克萨有限公司 | 诊断结核病的化合物和方法 |
| CN1388378A (zh) * | 2002-06-17 | 2003-01-01 | 四川大学 | 结核分枝杆菌诊断检测试剂 |
Non-Patent Citations (1)
| Title |
|---|
| Detection of Mycobacterium tuberculosis in Serum samples Using the Polymerase Chain Reaction;Staden et al;《Journal of Infection》;19980501;第36卷(第3期);摘要,第274页左栏第1段、右栏样品制备和DNA扩增部分,第275页结果部分,第276页讨论部分,第277页左栏第1段 * |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2019204844A1 (en) | 2019-07-25 |
| US20170369932A1 (en) | 2017-12-28 |
| EP2694680A4 (en) | 2014-09-10 |
| WO2012135815A3 (en) | 2012-12-27 |
| AU2012236109A1 (en) | 2013-11-21 |
| EP2694680A2 (en) | 2014-02-12 |
| CN103814139A (zh) | 2014-05-21 |
| US20140147851A1 (en) | 2014-05-29 |
| JP6430826B2 (ja) | 2018-11-28 |
| CN109280713A (zh) | 2019-01-29 |
| JP2014510538A (ja) | 2014-05-01 |
| RU2644672C2 (ru) | 2018-02-13 |
| WO2012135815A2 (en) | 2012-10-04 |
| AU2017203071A1 (en) | 2017-06-01 |
| JP2018117645A (ja) | 2018-08-02 |
| RU2013148806A (ru) | 2015-05-10 |
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