CN103800485B - A kind of Chinese medicine preparation for the treatment of herpes simplex keratitis - Google Patents

A kind of Chinese medicine preparation for the treatment of herpes simplex keratitis Download PDF

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Publication number
CN103800485B
CN103800485B CN201410089523.8A CN201410089523A CN103800485B CN 103800485 B CN103800485 B CN 103800485B CN 201410089523 A CN201410089523 A CN 201410089523A CN 103800485 B CN103800485 B CN 103800485B
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parts
radix
herpes simplex
chinese medicine
herba
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CN103800485A (en
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周比冠
黄彩峰
王红臻
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Zhou Biguan
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Abstract

The present invention relates to a kind of Chinese medicine preparation for the treatment of herpes simplex keratitis, be made up of the crude drug of following weight portion: Flos Lonicerae 18-22 part, Radix Isatidis 18-22 part, Herba Taraxaci 18-22 part, Ramulus Uncariae Cum Uncis 18-22 part, Radix Paeoniae Rubra 13-17 part, Spica Prunellae 13-17 part, Folium Isatidis 13-17 part, Fructus Forsythiae 8-12 part, Herba Schizonepetae 8-12 part, Radix Saposhnikoviae 8-12 part, Radix Scutellariae 8-12 part, Radix Platycodonis 8-12 part, Radix Bupleuri 8-12 part, Periostracum Cicadae 8-12 part, Flos Chrysanthemi 8-12 part, Herba Menthae 3-7 part, Radix Glycyrrhizae 3-7 part.The present invention has good effect, instant effect, has no side effect, advantage that relapse rate is low.

Description

A kind of Chinese medicine preparation for the treatment of herpes simplex keratitis
Technical field
The present invention relates to technical field of Chinese medicines, particularly relate to a kind of Chinese medicine preparation for the treatment of herpes simplex keratitis.
Background technology
Herpes simplex keratitis is common keratopathy the most serious at present, has in recent years and obviously rises and aggravation trend.It is mainly caused by varicella zoster virus, and very strong to the infectiousness of people, most people carries time virus.Some nonspecific stimulations such as flu, heating, malaria, emotion stimulation, menstruation, Exposure to Sunlight, application corticosteroid, nebula removing and wound etc. all may become the inducement of recurrence, all have that recur may after medicine and operative treatment.Due to recurrent exerbation, severe cases increases, serious threat visual function, therefore strengthens the research to primary disease, has become the problem that ophthalmology is urgently to be resolved hurrily.
At present, the medicine for the treatment of herpes simplex keratitis is more, but there is the deficiencies such as curative effect is not obvious, easy recurrence.
Summary of the invention
The technical problem to be solved in the present invention is: be solve the deficiencies in the prior art, the invention provides a kind of Chinese medicine preparation for the treatment of herpes simplex keratitis, and the present invention has good effect, instant effect, has no side effect, advantage that relapse rate is low.
Treat a Chinese medicine preparation for herpes simplex keratitis, be made up of the crude drug of following weight portion: Flos Lonicerae 18-22 part, Radix Isatidis 18-22 part, Herba Taraxaci 18-22 part, Ramulus Uncariae Cum Uncis 18-22 part, Radix Paeoniae Rubra 13-17 part, Spica Prunellae 13-17 part, Folium Isatidis 13-17 part, Fructus Forsythiae 8-12 part, Herba Schizonepetae 8-12 part, Radix Saposhnikoviae 8-12 part, Radix Scutellariae 8-12 part, Radix Platycodonis 8-12 part, Radix Bupleuri 8-12 part, Periostracum Cicadae 8-12 part, Flos Chrysanthemi 8-12 part, Herba Menthae 3-7 part, Radix Glycyrrhizae 3-7 part.
The Chinese medicine preparation of above-mentioned treatment herpes simplex keratitis, it is preferably: be made up of the crude drug of following weight portion: Flos Lonicerae 20 parts, Radix Isatidis 20 parts, Herba Taraxaci 20 parts, Ramulus Uncariae Cum Uncis 20 parts, Radix Paeoniae Rubra 15 parts, Spica Prunellae 15 parts, Folium Isatidis 15 parts, Fructus Forsythiae 10 parts, Herba Schizonepetae 10 parts, Radix Saposhnikoviae 10 parts, Radix Scutellariae 10 parts, Radix Platycodonis 10 parts, Radix Bupleuri 10 parts, Periostracum Cicadae 10 parts, Flos Chrysanthemi 10 parts, Herba Menthae 5 parts, 5 parts, Radix Glycyrrhizae.
The preparation method of the Chinese medicine preparation of above-mentioned treatment herpes simplex keratitis is: Chinese medicinal preparation method routinely makes oral decoction.
The pharmaceutical characteristic of each crude drug of the present invention is as follows:
Flos Lonicerae: meridian distribution of property and flavor: sweet, cold, returns lung, the heart, stomach warp; Effect: heat-clearing and toxic substances removing, wind-heat dissipating.
Radix Isatidis: meridian distribution of property and flavor: bitter, cold, GUIXIN, stomach warp; Effect: heat-clearing and toxic substances removing, removing heat from blood sore-throat relieving.
Herba Taraxaci: meridian distribution of property and flavor: bitter, sweet, cold, returns liver, stomach warp; Effect: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome.
Ramulus Uncariae Cum Uncis: meridian distribution of property and flavor: sweet, cool, returns liver, heart channel; Effect: heat clearing away suppressing the hyperactive liver, dispelling wind and relieving convulsion.
Radix Paeoniae Rubra: meridian distribution of property and flavor: bitter, be slightly cold, returns Liver Channel; Effect: clearing away heat and cooling blood, eliminating stasis to stop pain.
Spica Prunellae: meridian distribution of property and flavor: pungent, bitter, cold, returns liver, gallbladder meridian; Effect: relieve inflammation or internal heat, improving eyesight, eliminating stagnation, detumescence.
Folium Isatidis: meridian distribution of property and flavor: bitter, cold, GUIXIN, stomach warp; Effect: heat-clearing and toxic substances removing, blood cooling and ecchymoses removing.
Fructus Forsythiae: meridian distribution of property and flavor: bitter, be slightly cold, returns lung, the heart, gallbladder meridian; Effect: energy heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation.
Herba Schizonepetae: meridian distribution of property and flavor: pungent, tepor, returns lung, Liver Channel; Effect: induce sweat loose wind, rash.
Radix Saposhnikoviae: meridian distribution of property and flavor: sweet, pungent, tepor, returns spleen, bladder, Liver Channel; Effect: expelling pathogenic wind from the body surface, victory is wet, pain relieving, spasmolytic.
Radix Scutellariae: meridian distribution of property and flavor: bitter, cold, returns lung, gallbladder, spleen, large intestine, small intestine meridian; Effect: heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive.
Radix Platycodonis: meridian distribution of property and flavor: bitter, pungent, flat, attaches to the lung and stomach meridians; Effect: lung qi dispersing, sore-throat relieving, eliminate the phlegm, evacuation of pus.
Radix Bupleuri: meridian distribution of property and flavor: bitter, pungent, be slightly cold, returns liver, gallbladder meridian; Effect: induce sweat and bring down a fever, dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy.
Periostracum Cicadae: meridian distribution of property and flavor: sweet, cold, returns lung, Liver Channel; Effect: loose wind heat extraction, sore-throat relieving, rash, nebula removing, spasmolytic.
Flos Chrysanthemi: meridian distribution of property and flavor: sweet, bitter, pungent, be slightly cold, returns liver, lung meridian; Effect: wind and heat dispersing, removing toxic substances, improving eyesight.
Herba Menthae: meridian distribution of property and flavor: pungent, cool, returns lung, Liver Channel; Effect: dispelling wind, heat radiation, wards off dirty, removing toxic substances.
Radix Glycyrrhizae: meridian distribution of property and flavor: sweet, flat, GUIXIN, lung, spleen, stomach warp; Effect: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.
The beneficial effect that the present invention is compared with prior art had is: the present invention is under Traditional Chinese medical theory and clinical experience instruct, choose each crude drug and proportioning thereof, there is the function of expelling pathogenic wind from the body surface, heat-clearing and toxic substances removing, benefiting QI and nourishing blood, realize the object for the treatment of herpes simplex keratitis.
Below in conjunction with clinical experiment, beneficial effect of the present invention is described:
(1) clinical data: the present invention treats herpes simplex keratitis patient 38 example (38) altogether, wherein male 21 examples (21), female 17 example (17), the age is 8-60 year.
(2) Therapeutic Method: Chinese medicine decoction of the present invention, every day 1 pair, point to take for 3 times, early, middle and lately respectively takes 1 time.
(3) the standard of curative effect evaluation: cure: irritated eyes disappears, congested disappearance, corneal infiltration stove heals, and fluorescein corneal dyeing is not painted; Take a turn for the better: irritated eyes obviously alleviates, and corneal infiltration stove range shorter or infiltration alleviate, and fluorescent staining is painted; Do not heal: irritated eyes is obvious, corneal infiltration stove is without reducing or expanding, deepen, and fluorescein corneal dyeing is obviously painted.
(4) therapeutic outcome: the present invention treats herpes simplex keratitis patient 38 example altogether, through the treatment of 8-35 days, cures 29 examples, account for 76.3%, take a turn for the better 8 examples, accounts for 21.1%, and do not heal 1 example, account for 2.6%, effective percentage is 97.4%, has no any side effect, through following up a case by regular visits to 1 year, have 1 example recurrence, relapse rate accounts for 2.6%; Result shows, the present invention has good effect, instant effect, has no side effect, advantage that relapse rate is low.
(5) model case:
1, river so-and-so, female, 35 years old, left eye photophobia, shed tears, blurred vision 7 days, vision left eye 1.0, right eye 1.5, conjunctiva of left eye mild hyperaemia, the visible intensive point-like of angle 2% fluorescent staining is painted, tongue fur BOHUANG, stringy pulse; Take Chinese medicine preparation of the present invention to take a turn for the better after 5 days, cure after 10 days, follow up a case by regular visits to and do not recur for 1 year.
2, Korea Spro so-and-so, man, 40 years old, right eye suffers from herpes simplex keratitis 2 months, bad during fashion, through various therapy, obstinate, come to see a doctor, right eye mixed congestion, there is the herpes of a soybean grain and little beans size at 3 points around cornea, 7 places, slight photophobia is shed tears, red tongue, thin and yellow fur, stringy,thready and rapid pulse; Take Chinese medicine preparation of the present invention to cure for 20 days, follow up a case by regular visits to and do not recur half a year.
Detailed description of the invention
Embodiment 1:
Treat a Chinese medicine preparation for herpes simplex keratitis, be made up of the crude drug of following weight portion: Flos Lonicerae 18 parts, Radix Isatidis 18 parts, Herba Taraxaci 18 parts, Ramulus Uncariae Cum Uncis 18 parts, Radix Paeoniae Rubra 13 parts, Spica Prunellae 13 parts, Folium Isatidis 13 parts, Fructus Forsythiae 8 parts, Herba Schizonepetae 8 parts, Radix Saposhnikoviae 8 parts, Radix Scutellariae 8 parts, Radix Platycodonis 8 parts, Radix Bupleuri 8 parts, Periostracum Cicadae 8 parts, Flos Chrysanthemi 8 parts, Herba Menthae 3 parts, 3 parts, Radix Glycyrrhizae.
Its preparation method is: Chinese medicinal preparation method routinely makes oral decoction.
Embodiment 2:
Treat a Chinese medicine preparation for herpes simplex keratitis, be made up of the crude drug of following weight portion: Flos Lonicerae 20 parts, Radix Isatidis 20 parts, Herba Taraxaci 20 parts, Ramulus Uncariae Cum Uncis 20 parts, Radix Paeoniae Rubra 15 parts, Spica Prunellae 15 parts, Folium Isatidis 15 parts, Fructus Forsythiae 10 parts, Herba Schizonepetae 10 parts, Radix Saposhnikoviae 10 parts, Radix Scutellariae 10 parts, Radix Platycodonis 10 parts, Radix Bupleuri 10 parts, Periostracum Cicadae 10 parts, Flos Chrysanthemi 10 parts, Herba Menthae 5 parts, 5 parts, Radix Glycyrrhizae.
Its preparation method is: Chinese medicinal preparation method routinely makes oral decoction.
Embodiment 3:
Treat a Chinese medicine preparation for herpes simplex keratitis, be made up of the crude drug of following weight portion: Flos Lonicerae 22 parts, Radix Isatidis 22 parts, Herba Taraxaci 22 parts, Ramulus Uncariae Cum Uncis 22 parts, Radix Paeoniae Rubra 17 parts, Spica Prunellae 17 parts, Folium Isatidis 17 parts, Fructus Forsythiae 12 parts, Herba Schizonepetae 12 parts, Radix Saposhnikoviae 12 parts, Radix Scutellariae 12 parts, Radix Platycodonis 12 parts, Radix Bupleuri 12 parts, Periostracum Cicadae 12 parts, Flos Chrysanthemi 12 parts, Herba Menthae 7 parts, 7 parts, Radix Glycyrrhizae.
Its preparation method is: Chinese medicinal preparation method routinely makes oral decoction.

Claims (3)

1. treat a Chinese medicine preparation for herpes simplex keratitis, it is characterized in that: be made up of the crude drug of following weight portion: Flos Lonicerae 18-22 part, Radix Isatidis 18-22 part, Herba Taraxaci 18-22 part, Ramulus Uncariae Cum Uncis 18-22 part, Radix Paeoniae Rubra 13-17 part, Spica Prunellae 13-17 part, Folium Isatidis 13-17 part, Fructus Forsythiae 8-12 part, Herba Schizonepetae 8-12 part, Radix Saposhnikoviae 8-12 part, Radix Scutellariae 8-12 part, Radix Platycodonis 8-12 part, Radix Bupleuri 8-12 part, Periostracum Cicadae 8-12 part, Flos Chrysanthemi 8-12 part, Herba Menthae 3-7 part, Radix Glycyrrhizae 3-7 part.
2. the Chinese medicine preparation for the treatment of herpes simplex keratitis according to claim 1, is characterized in that: be made up of the crude drug of following weight portion: Flos Lonicerae 20 parts, Radix Isatidis 20 parts, Herba Taraxaci 20 parts, Ramulus Uncariae Cum Uncis 20 parts, Radix Paeoniae Rubra 15 parts, Spica Prunellae 15 parts, Folium Isatidis 15 parts, Fructus Forsythiae 10 parts, Herba Schizonepetae 10 parts, Radix Saposhnikoviae 10 parts, Radix Scutellariae 10 parts, Radix Platycodonis 10 parts, Radix Bupleuri 10 parts, Periostracum Cicadae 10 parts, Flos Chrysanthemi 10 parts, Herba Menthae 5 parts, 5 parts, Radix Glycyrrhizae.
3. the preparation method of the Chinese medicine preparation for the treatment of herpes simplex keratitis according to claim 1 and 2, is characterized in that: Chinese medicinal preparation method routinely makes oral decoction.
CN201410089523.8A 2014-03-12 2014-03-12 A kind of Chinese medicine preparation for the treatment of herpes simplex keratitis Expired - Fee Related CN103800485B (en)

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CN104367664A (en) * 2014-12-03 2015-02-25 西宁意格知识产权咨询服务有限公司 Anti-herpes simplex I virus traditional Chinese medicine composition and preparation method thereof
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CN105395718A (en) * 2015-12-21 2016-03-16 青岛市市立医院 Externally applied traditional Chinese medicine composition used for treating viral keratitis
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CN107737230A (en) * 2017-09-20 2018-02-27 王崟 A kind of Chinese medicine of energy rapid, effective treatment viral keratitis
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