CN105362484A - Traditional Chinese medicine composition for treating keratitis and preparation method thereof - Google Patents

Traditional Chinese medicine composition for treating keratitis and preparation method thereof Download PDF

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CN105362484A
CN105362484A CN201510829708.2A CN201510829708A CN105362484A CN 105362484 A CN105362484 A CN 105362484A CN 201510829708 A CN201510829708 A CN 201510829708A CN 105362484 A CN105362484 A CN 105362484A
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chinese medicine
radix
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禤燕华
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/85Verbenaceae (Verbena family)
    • A61K36/855Clerodendrum, e.g. glorybower
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • A61K36/195Strobilanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238Saposhnikovia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315Isatis, e.g. Dyer's woad
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/51Gentianaceae (Gentian family)
    • A61K36/515Gentiana
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/538Schizonepeta
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/85Verbenaceae (Verbena family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2068Compounds of unknown constitution, e.g. material from plants or animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Abstract

The invention relates to a traditional Chinese medicine composition for treating keratitis and a preparation method thereof. The traditional Chinese medicine composition comprises, by weight, 12-14g of radix sileris, 6-8g of herba schizonepetae, 15-20g of radix bupleuri, 10-13g of fructus viticis, 20-24g of radix gentianae, 12-14g of radix scutellariae, 12-14g of flos lonicerae, 15-18g of folium isatidis, 12-14g of radix paeoniae rubra, 10-12g of caulis akebiae and 6-8g of radix glycyrrhizae. The traditional Chinese medicine composition is capable of treating the keratitis and various diseases caused by the keratitis and evident in effect.

Description

A kind of Chinese medicine composition for the treatment of keratitis and preparation method thereof
Technical field
The present invention relates to Chinese medicine composition, in particular for the treatment Chinese medicine composition of keratitis and the preparation method of medicine soup and pill thereof.
Background technology
Keratitis is divided into ulcerative keratitis (corneal ulcer), non-ulcerative keratitis (deep keratitis) two class.By endogenous cause of ill, exopathogenic factor Different factor causes.Because of ocular surface burns, the inflammation that antibacterial and Virus entry cornea cause.Suffer from eye and have foreign body sensation, twinge is burn feeling even.Bulbar conjunctiva surface Combination is congested, with keeping in dark place, shed tears, the symptom such as visual disorder and secretions increase.Anterior corneal surface infiltrates ulcer.The ulcerative keratitis overwhelming majority caused by foeign element, i.e. the inflammation that occurred by outer intrusion corneal epithelial cell layer of the Infectious diseases factor.
Except neuroparalytic keratitis, most keratitis patients has intensity inflammation symptom, as pain, photophobia, sheds tears and blepharospasm.Keratitis patients not only has ciliary congestion, also has iris congested.All can there is edema in the bulbar conjunctiva of severe patient even eyelid.
Corneal inflammation must make vision be affected more or less, especially invades pupil region person with inflammation even more serious.The corneal scarring formed after ulcer healing not only hinders light to enter ophthalmic, and anterior corneal surface flexibility and dioptric refraction power can be made to change, and object can not be focused on the retina and form clear image, thus vision reduces.The involved of vision depends on the position at cicatrix place completely, if be positioned at cornea center, although cicatrix is very little, but it is very large to affect one's power of vision.
Existing treatment keratitis and the many side effect of Western medicine of various diseases caused by it large, long-term taking can produce very large injury to health, and relapse rate is high, the Chinese medicine of motherland's traditional medicine is as the effective Therapeutic Method of one, be widely used in the clinical treatment of various diseases, especially determined curative effect, with a high credibility in the improvement of the scorching disease of corneal, all does a lot of work, has the therapeutical effect of its uniqueness in rationale and clinical practice.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of Chinese medicine composition for the treatment of keratitis and preparation method thereof, the disease of various diseases that this Chinese medicine composition can be treated keratitis and be caused.
For solving the problems of the technologies described above, one of technical scheme of the present invention: a kind of Chinese medicine composition for the treatment of keratitis, traditional Chinese medicine composite and weight portion are: Radix Saposhnikoviae 12-14 gram, Herba Schizonepetae 6-8 gram, Radix Bupleuri 15-20 gram, Fructus Viticis 10-13 gram, Radix Gentianae 20-24 gram, Radix Scutellariae 12-14 gram, Flos Lonicerae 12-14 gram, Folium Isatidis 15-18 gram, Radix Paeoniae Rubra 12-14 gram, Caulis Akebiae l0-12 gram, Radix Glycyrrhizae 6-8 gram.
As improvement, traditional Chinese medicine composite and weight portion are: Radix Saposhnikoviae 12 grams, Herba Schizonepetae 6 grams, Radix Bupleuri 15 grams, Fructus Viticis 10 grams, Radix Gentianae 20 grams, Radix Scutellariae 12 grams, Flos Lonicerae 12 grams, Folium Isatidis 15 grams, Radix Paeoniae Rubra 12 grams, Caulis Akebiae l0 gram, 6 grams, Radix Glycyrrhizae.
As improvement, traditional Chinese medicine composite and weight portion are: Radix Saposhnikoviae 13 grams, Herba Schizonepetae 7 grams, Radix Bupleuri 16 grams, Fructus Viticis 12 grams, Radix Gentianae 22 grams, Radix Scutellariae 13 grams, Flos Lonicerae 13 grams, Folium Isatidis 16 grams, Radix Paeoniae Rubra 13 grams, Caulis Akebiae 11 grams, 7 grams, Radix Glycyrrhizae.
As improvement, traditional Chinese medicine composite and weight portion are: Radix Saposhnikoviae 14 grams, Herba Schizonepetae 8 grams, Radix Bupleuri 20 grams, Fructus Viticis 13 grams, Radix Gentianae 24 grams, Radix Scutellariae 14 grams, Flos Lonicerae 14 grams, Folium Isatidis 18 grams, Radix Paeoniae Rubra 14 grams, Caulis Akebiae 12 grams, 8 grams, Radix Glycyrrhizae.
For solving the problems of the technologies described above, technical solution of the present invention two: a kind of decoction preparation method for the treatment of the Chinese medicine composition of keratitis, comprises the following steps:
(1) utilize cold water soak raw material of Chinese medicine 60 minutes, during immersion, the water surface wants submergence raw material of Chinese medicine, and raw material of Chinese medicine cell is re-inflated, and soluble component is stripping gradually, improves decocting rate;
(2) raw material of Chinese medicine is put into bag to carry out beaing fragmentation;
(3) raw material of Chinese medicine is poured in crock, add Chinese medicine composition gross weight 3-5 clear water doubly;
(4) first with high heat Chinese medicine is boiled, the more micro-20-30min that boils of slow fire;
(5) after leaching medicinal liquid, medicinal residues are put into cotton, after medicine is slightly cool, the medicinal liquid adsorbed in slag of getting it filled is twisted in pressurization.
For solving the problems of the technologies described above, technical solution of the present invention three: a kind of pill preparation method for the treatment of the Chinese medicine composition of keratitis, comprises the following steps:
(1) powder is beaten: cured by raw material of Chinese medicine slow fire or after drying of being exposed to the sun, break into fine powder with powder beater, putting into disinfection basin before preparing pill for subsequent use;
(2) honey is joined: prepare Mel with the weight of medicated powder in the ratio of 1:1.2-1.5;
(3) refined honey: first endure with high heat during refined honey and boil, then change slow fire into endure slowly, put one bowl of cold water aside simultaneously, and note the color of observing Mel, when finding Mel yellowing foam, in Mel, be stained with one with bamboo chopsticks, then bamboo chopsticks are moved to above cold water bowl, Mel is allowed to instill in water, if Mel does not scatter and sinks to the bottom in water, even if Mel refining is good;
(4) adjust medicine with and medicine: the Mel spoon of tempering is poured in the medicated powder of disinfection basin splendid attire, stirs in medicated powder with thick bamboo chopsticks simultaneously, while the limit of falling Mel adjust medicated powder, when can't see dry medicated powder stop add honey;
(5) rubbing with and ball: for avoiding medicine roll into a ball sticky hands or sticking device tool, rubbing can be carried out in the centre of the palm with a small amount of glycerol, Oleum sesami or Semen arachidis hypogaeae oil drop with during ball, not only not easily sticks like this, can also make the round and smooth light of pill;
(6) packaging and storage: the honeyed pill made, profile rounding is smooth, and surface compact moistens, and without fibres visible or other heterochromatic point, treat pill diaphoresis 3 days, appearance is hardening, then wraps with paraffin paper, cellophane, plastic bag or wax shell, is stored in shady and cool drying place.
Be prepared into the Chinese medicine composition of pill, be easier to preserve, and instructions of taking be simple, industrialization in enormous quantities can be realized and produce.
The beneficial effect that the present invention is compared with prior art brought is:
Adopting the various raw materials of said components proportioning, combine the drug effect of each taste Chinese medicine, there is synergism between the raw material in formula, drug effect is enhanced, and effective drug duration is longer, has no side effect in more thorough that drug effect is played of reasonably arranging in pairs or groups.
The symptom of various diseases that Chinese medicine composition of the present invention effectively can improve keratitis and be caused by it, and curative effect is lasting, and Be very effective, has no side effect, and is beneficial to clinical expansion, and total effective rate can reach more than 90%.
Detailed description of the invention
Embodiment 1
Treat a Chinese medicine composition for keratitis, traditional Chinese medicine composite and weight portion are: Radix Saposhnikoviae 12 grams, Herba Schizonepetae 6 grams, Radix Bupleuri 15 grams, Fructus Viticis 10 grams, Radix Gentianae 20 grams, Radix Scutellariae 12 grams, Flos Lonicerae 12 grams, Folium Isatidis 15 grams, Radix Paeoniae Rubra 12 grams, Caulis Akebiae l0 gram, 6 grams, Radix Glycyrrhizae.
The medicine soup preparation method of Chinese medicine composition, comprises the following steps:
(1) utilize cold water soak raw material of Chinese medicine 60 minutes, during immersion, the water surface wants submergence raw material of Chinese medicine, and raw material of Chinese medicine cell is re-inflated, and soluble component is stripping gradually, improves decocting rate;
(2) raw material of Chinese medicine is put into bag to carry out beaing fragmentation;
(3) raw material of Chinese medicine is poured in crock, add Chinese medicine composition gross weight 3-5 clear water doubly;
(4) first with high heat Chinese medicine is boiled, the more micro-20-30min that boils of slow fire;
(5) after leaching medicinal liquid, medicinal residues are put into cotton, after medicine is slightly cool, the medicinal liquid adsorbed in slag of getting it filled is twisted in pressurization.
Instructions of taking: decocting 2 mixings, point morning and evening 2 decoction being taken warmly, every day 1 dose.It within 15 days, was 1 course for the treatment of.
The present invention can also make pill, and its preparation method is as follows:
(1) powder is beaten: cured by raw material of Chinese medicine slow fire or after drying of being exposed to the sun, break into fine powder with powder beater, putting into disinfection basin before preparing pill for subsequent use;
(2) honey is joined: prepare Mel with the weight of medicated powder in the ratio of 1:1.2-1.5;
(3) refined honey: first endure with high heat during refined honey and boil, then change slow fire into endure slowly, put one bowl of cold water aside simultaneously, and note the color of observing Mel, when finding Mel yellowing foam, in Mel, be stained with one with bamboo chopsticks, then bamboo chopsticks are moved to above cold water bowl, Mel is allowed to instill in water, if Mel does not scatter and sinks to the bottom in water, even if Mel refining is good;
(4) adjust medicine with and medicine: the Mel spoon of tempering is poured in the medicated powder of disinfection basin splendid attire, stirs in medicated powder with thick bamboo chopsticks simultaneously, while the limit of falling Mel adjust medicated powder, when can't see dry medicated powder stop add honey;
(5) rubbing with and ball: for avoiding medicine roll into a ball sticky hands or sticking device tool, rubbing can be carried out in the centre of the palm with a small amount of glycerol, Oleum sesami or Semen arachidis hypogaeae oil drop with during ball, not only not easily sticks like this, can also make the round and smooth light of pill;
(6) packaging and storage: the honeyed pill made, profile rounding is smooth, and surface compact moistens, and without fibres visible or other heterochromatic point, treat pill diaphoresis 3 days, appearance is hardening, then wraps with paraffin paper, cellophane, plastic bag or wax shell, is stored in shady and cool drying place.
Embodiment 2
Treat a Chinese medicine composition for keratitis, traditional Chinese medicine composite and weight portion are: Radix Saposhnikoviae 13 grams, Herba Schizonepetae 7 grams, Radix Bupleuri 16 grams, Fructus Viticis 12 grams, Radix Gentianae 22 grams, Radix Scutellariae 13 grams, Flos Lonicerae 13 grams, Folium Isatidis 16 grams, Radix Paeoniae Rubra 13 grams, Caulis Akebiae 11 grams, 7 grams, Radix Glycyrrhizae.
The medicine soup preparation method of Chinese medicine composition, comprises the following steps:
(1) utilize cold water soak raw material of Chinese medicine 60 minutes, during immersion, the water surface wants submergence raw material of Chinese medicine, and raw material of Chinese medicine cell is re-inflated, and soluble component is stripping gradually, improves decocting rate;
(2) raw material of Chinese medicine is put into bag to carry out beaing fragmentation;
(3) raw material of Chinese medicine is poured in crock, add Chinese medicine composition gross weight 3-5 clear water doubly;
(4) first with high heat Chinese medicine is boiled, the more micro-20-30min that boils of slow fire;
(5) after leaching medicinal liquid, medicinal residues are put into cotton, after medicine is slightly cool, the medicinal liquid adsorbed in slag of getting it filled is twisted in pressurization.
Instructions of taking: decocting 2 mixings, point morning and evening 2 decoction being taken warmly, every day 1 dose.It within 15 days, was 1 course for the treatment of.
The present invention can also make pill, and its preparation method is as follows:
(1) powder is beaten: cured by raw material of Chinese medicine slow fire or after drying of being exposed to the sun, break into fine powder with powder beater, putting into disinfection basin before preparing pill for subsequent use;
(2) honey is joined: prepare Mel with the weight of medicated powder in the ratio of 1:1.2-1.5;
(3) refined honey: first endure with high heat during refined honey and boil, then change slow fire into endure slowly, put one bowl of cold water aside simultaneously, and note the color of observing Mel, when finding Mel yellowing foam, in Mel, be stained with one with bamboo chopsticks, then bamboo chopsticks are moved to above cold water bowl, Mel is allowed to instill in water, if Mel does not scatter and sinks to the bottom in water, even if Mel refining is good;
(4) adjust medicine with and medicine: the Mel spoon of tempering is poured in the medicated powder of disinfection basin splendid attire, stirs in medicated powder with thick bamboo chopsticks simultaneously, while the limit of falling Mel adjust medicated powder, when can't see dry medicated powder stop add honey;
(5) rubbing with and ball: for avoiding medicine roll into a ball sticky hands or sticking device tool, rubbing can be carried out in the centre of the palm with a small amount of glycerol, Oleum sesami or Semen arachidis hypogaeae oil drop with during ball, not only not easily sticks like this, can also make the round and smooth light of pill;
(6) packaging and storage: the honeyed pill made, profile rounding is smooth, and surface compact moistens, and without fibres visible or other heterochromatic point, treat pill diaphoresis 3 days, appearance is hardening, then wraps with paraffin paper, cellophane, plastic bag or wax shell, is stored in shady and cool drying place.
Embodiment 3
Treat a Chinese medicine composition for keratitis, traditional Chinese medicine composite and weight portion are: Radix Saposhnikoviae 14 grams, Herba Schizonepetae 8 grams, Radix Bupleuri 20 grams, Fructus Viticis 13 grams, Radix Gentianae 24 grams, Radix Scutellariae 14 grams, Flos Lonicerae 14 grams, Folium Isatidis 18 grams, Radix Paeoniae Rubra 14 grams, Caulis Akebiae 12 grams, 8 grams, Radix Glycyrrhizae.
The medicine soup preparation method of Chinese medicine composition, comprises the following steps:
(1) utilize cold water soak raw material of Chinese medicine 60 minutes, during immersion, the water surface wants submergence raw material of Chinese medicine, and raw material of Chinese medicine cell is re-inflated, and soluble component is stripping gradually, improves decocting rate;
(2) raw material of Chinese medicine is put into bag to carry out beaing fragmentation;
(3) raw material of Chinese medicine is poured in crock, add Chinese medicine composition gross weight 3-5 clear water doubly;
(4) first with high heat Chinese medicine is boiled, the more micro-20-30min that boils of slow fire;
(5) after leaching medicinal liquid, medicinal residues are put into cotton, after medicine is slightly cool, the medicinal liquid adsorbed in slag of getting it filled is twisted in pressurization.
Instructions of taking: decocting 2 mixings, point morning and evening 2 decoction being taken warmly, every day 1 dose.It within 15 days, was 1 course for the treatment of.
The present invention can also make pill, and its preparation method is as follows:
(1) powder is beaten: cured by raw material of Chinese medicine slow fire or after drying of being exposed to the sun, break into fine powder with powder beater, putting into disinfection basin before preparing pill for subsequent use;
(2) honey is joined: prepare Mel with the weight of medicated powder in the ratio of 1:1.2-1.5;
(3) refined honey: first endure with high heat during refined honey and boil, then change slow fire into endure slowly, put one bowl of cold water aside simultaneously, and note the color of observing Mel, when finding Mel yellowing foam, in Mel, be stained with one with bamboo chopsticks, then bamboo chopsticks are moved to above cold water bowl, Mel is allowed to instill in water, if Mel does not scatter and sinks to the bottom in water, even if Mel refining is good;
(4) adjust medicine with and medicine: the Mel spoon of tempering is poured in the medicated powder of disinfection basin splendid attire, stirs in medicated powder with thick bamboo chopsticks simultaneously, while the limit of falling Mel adjust medicated powder, when can't see dry medicated powder stop add honey;
(5) rubbing with and ball: for avoiding medicine roll into a ball sticky hands or sticking device tool, rubbing can be carried out in the centre of the palm with a small amount of glycerol, Oleum sesami or Semen arachidis hypogaeae oil drop with during ball, not only not easily sticks like this, can also make the round and smooth light of pill;
(6) packaging and storage: the honeyed pill made, profile rounding is smooth, and surface compact moistens, and without fibres visible or other heterochromatic point, treat pill diaphoresis 3 days, appearance is hardening, then wraps with paraffin paper, cellophane, plastic bag or wax shell, is stored in shady and cool drying place.
Embodiment 4
Treat a Chinese medicine composition for keratitis, traditional Chinese medicine composite and weight portion are: Radix Saposhnikoviae 13 grams, Herba Schizonepetae 7 grams, Radix Bupleuri 15 grams, Fructus Viticis 10 grams, Radix Gentianae 23 grams, Radix Scutellariae 12 grams, Flos Lonicerae 13 grams, Folium Isatidis 17 grams, Radix Paeoniae Rubra 12 grams, Caulis Akebiae l1 gram, 7 grams, Radix Glycyrrhizae.
The medicine soup preparation method of Chinese medicine composition, comprises the following steps:
(1) utilize cold water soak raw material of Chinese medicine 60 minutes, during immersion, the water surface wants submergence raw material of Chinese medicine, and raw material of Chinese medicine cell is re-inflated, and soluble component is stripping gradually, improves decocting rate;
(2) raw material of Chinese medicine is put into bag to carry out beaing fragmentation;
(3) raw material of Chinese medicine is poured in crock, add Chinese medicine composition gross weight 3-5 clear water doubly;
(4) first with high heat Chinese medicine is boiled, the more micro-20-30min that boils of slow fire;
(5) after leaching medicinal liquid, medicinal residues are put into cotton, after medicine is slightly cool, the medicinal liquid adsorbed in slag of getting it filled is twisted in pressurization.
Instructions of taking: decocting 2 mixings, point morning and evening 2 decoction being taken warmly, every day 1 dose.It within 15 days, was 1 course for the treatment of.
The present invention can also make pill, and its preparation method is as follows:
(1) powder is beaten: cured by raw material of Chinese medicine slow fire or after drying of being exposed to the sun, break into fine powder with powder beater, putting into disinfection basin before preparing pill for subsequent use;
(2) honey is joined: prepare Mel with the weight of medicated powder in the ratio of 1:1.2-1.5;
(3) refined honey: first endure with high heat during refined honey and boil, then change slow fire into endure slowly, put one bowl of cold water aside simultaneously, and note the color of observing Mel, when finding Mel yellowing foam, in Mel, be stained with one with bamboo chopsticks, then bamboo chopsticks are moved to above cold water bowl, Mel is allowed to instill in water, if Mel does not scatter and sinks to the bottom in water, even if Mel refining is good;
(4) adjust medicine with and medicine: the Mel spoon of tempering is poured in the medicated powder of disinfection basin splendid attire, stirs in medicated powder with thick bamboo chopsticks simultaneously, while the limit of falling Mel adjust medicated powder, when can't see dry medicated powder stop add honey;
(5) rubbing with and ball: for avoiding medicine roll into a ball sticky hands or sticking device tool, rubbing can be carried out in the centre of the palm with a small amount of glycerol, Oleum sesami or Semen arachidis hypogaeae oil drop with during ball, not only not easily sticks like this, can also make the round and smooth light of pill;
(6) packaging and storage: the honeyed pill made, profile rounding is smooth, and surface compact moistens, and without fibres visible or other heterochromatic point, treat pill diaphoresis 3 days, appearance is hardening, then wraps with paraffin paper, cellophane, plastic bag or wax shell, is stored in shady and cool drying place.
Experimental example 1:
Zhang, man, 45 years old, first visit on February 1 in 2010: conscious photophobia, shed tears, puckery pain, but congestive symptom is comparatively light, hold concurrently fever with chills, pharyngalgia, tongue fur BOHUANG, floating and rapid pulse.Tcm diagnosis: keratitis.Prepare decoction liquor according to embodiment 1, after taking two courses for the treatment of continuously, symptom is alleviated to some extent; After taking two courses for the treatment of more continuously, conscious photophobia, shed tears, the disease of puckery pain is very significantly improved; Congestive symptom, the symptom such as fever with chills, pharyngalgia of holding concurrently are eliminated.
Experimental example 2
Zhang, female, 32 years old, December in 2012 first visit on the 21st: conscious photophobia, shed tears, puckery pain, but congestive symptom is comparatively light, pharyngalgia.Tcm diagnosis: keratitis.Prepare decoction liquor according to embodiment 2, after taking two courses for the treatment of continuously, symptom is alleviated to some extent; After taking two courses for the treatment of more continuously, conscious photophobia, shed tears, the disease of puckery pain is very significantly improved; Congestive symptom, the symptoms such as pharyngalgia are eliminated.
Medicine obtained in above-described embodiment 1-4 is carried out the efficient test of various diseases for the treatment of keratitis and being caused by it.Select tcm diagnosis keratitis to be standard: conscious photophobia, shed tears, puckery pain, but congestive symptom is comparatively light, hold concurrently fever with chills, pharyngalgia, tongue fur BOHUANG, floating and rapid pulse.The patient selecting 124 examples to have as above symptom has carried out clinical observation on the therapeutic effect, wherein male 70 example, women 54 example, age characteristics 25-50 year, 41.3 years old mean age.Be divided into four groups at random.
Criterion of therapeutical effect is as follows:
Effective: body constitution strengthen, conscious photophobia, shed tears, puckery pain, congestive symptom, hold concurrently fever with chills, pharyngalgia, tongue fur BOHUANG, the symptoms such as floating and rapid pulse are obviously alleviated;
Effective: body constitution strengthens, conscious photophobia, shed tears, the symptom such as puckery pain alleviates to some extent;
Invalid: symptom is unchanged.
Add up to effectively total with the above two, result is as following table:
Specimen types Effective Effectively Invalid Total effective rate
Embodiment 1 26 3 2 93.55%
Embodiment 2 25 4 2 93.55%
Embodiment 3 24 4 2 93.33%
Embodiment 4 24 5 3 90.63%
Can be known by above result of the test, have traditional Chinese medicine composition for treating keratitis provided by the invention and various diseases effect of causing remarkable, have no side effect, total effective rate can reach more than 90%.

Claims (6)

1. a kind of Chinese medicine composition for the treatment of keratitis, it is characterized in that: traditional Chinese medicine composite and weight portion are: Radix Saposhnikoviae 12-14 gram, Herba Schizonepetae 6-8 gram, Radix Bupleuri 15-20 gram, Fructus Viticis 10-13 gram, Radix Gentianae 20-24 gram, Radix Scutellariae 12-14 gram, Flos Lonicerae 12-14 gram, Folium Isatidis 15-18 gram, Radix Paeoniae Rubra 12-14 gram, Caulis Akebiae l0-12 gram, Radix Glycyrrhizae 6-8 gram.
2. a kind of Chinese medicine composition for the treatment of keratitis according to claim 1, it is characterized in that: traditional Chinese medicine composite and weight portion are: Radix Saposhnikoviae 12 grams, Herba Schizonepetae 6 grams, Radix Bupleuri 15 grams, Fructus Viticis 10 grams, Radix Gentianae 20 grams, Radix Scutellariae 12 grams, Flos Lonicerae 12 grams, Folium Isatidis 15 grams, Radix Paeoniae Rubra 12 grams, Caulis Akebiae l0 gram, 6 grams, Radix Glycyrrhizae.
3. a kind of Chinese medicine composition for the treatment of keratitis according to claim 1, it is characterized in that: traditional Chinese medicine composite and weight portion are: Radix Saposhnikoviae 13 grams, Herba Schizonepetae 7 grams, Radix Bupleuri 16 grams, Fructus Viticis 12 grams, Radix Gentianae 22 grams, Radix Scutellariae 13 grams, Flos Lonicerae 13 grams, Folium Isatidis 16 grams, Radix Paeoniae Rubra 13 grams, Caulis Akebiae 11 grams, 7 grams, Radix Glycyrrhizae.
4. a kind of Chinese medicine composition for the treatment of keratitis according to claim 1, it is characterized in that: traditional Chinese medicine composite and weight portion are: Radix Saposhnikoviae 14 grams, Herba Schizonepetae 8 grams, Radix Bupleuri 20 grams, Fructus Viticis 13 grams, Radix Gentianae 24 grams, Radix Scutellariae 14 grams, Flos Lonicerae 14 grams, Folium Isatidis 18 grams, Radix Paeoniae Rubra 14 grams, Caulis Akebiae 12 grams, 8 grams, Radix Glycyrrhizae.
5. a decoction preparation method for the Chinese medicine composition for the treatment of keratitis as claimed in claim 1, is characterized in that: comprise the following steps:
(1) utilize cold water soak raw material of Chinese medicine 60 minutes, during immersion, the water surface wants submergence raw material of Chinese medicine, and raw material of Chinese medicine cell is re-inflated, and soluble component is stripping gradually, improves decocting rate;
(2) raw material of Chinese medicine is put into bag to carry out beaing fragmentation;
(3) raw material of Chinese medicine is poured in crock, add Chinese medicine composition gross weight 3-5 clear water doubly;
(4) first with high heat Chinese medicine is boiled, the more micro-20-30min that boils of slow fire;
(5) after leaching medicinal liquid, medicinal residues are put into cotton, after medicine is slightly cool, the medicinal liquid adsorbed in slag of getting it filled is twisted in pressurization.
6. a pill preparation method for the Chinese medicine composition for the treatment of keratitis as claimed in claim 1, is characterized in that: comprise the following steps:
(1) powder is beaten: cured by raw material of Chinese medicine slow fire or after drying of being exposed to the sun, break into fine powder with powder beater, putting into disinfection basin before preparing pill for subsequent use;
(2) honey is joined: prepare Mel with the weight of medicated powder in the ratio of 1:1.2-1.5;
(3) refined honey: first endure with high heat during refined honey and boil, then change slow fire into endure slowly, put one bowl of cold water aside simultaneously, and note the color of observing Mel, when finding Mel yellowing foam, in Mel, be stained with one with bamboo chopsticks, then bamboo chopsticks are moved to above cold water bowl, Mel is allowed to instill in water, if Mel does not scatter and sinks to the bottom in water, even if Mel refining is good;
(4) adjust medicine with and medicine: the Mel spoon of tempering is poured in the medicated powder of disinfection basin splendid attire, stirs in medicated powder with thick bamboo chopsticks simultaneously, while the limit of falling Mel adjust medicated powder, when can't see dry medicated powder stop add honey;
(5) rubbing with and ball: for avoiding medicine roll into a ball sticky hands or sticking device tool, rubbing can be carried out in the centre of the palm with a small amount of glycerol, Oleum sesami or Semen arachidis hypogaeae oil drop with during ball, not only not easily sticks like this, can also make the round and smooth light of pill;
(6) packaging and storage: the honeyed pill made, profile rounding is smooth, and surface compact moistens, and without fibres visible or other heterochromatic point, treat pill diaphoresis 3 days, appearance is hardening, then wraps with paraffin paper, cellophane, plastic bag or wax shell, is stored in shady and cool drying place.
CN201510829708.2A 2015-11-25 2015-11-25 Traditional Chinese medicine composition for treating keratitis and preparation method thereof Pending CN105362484A (en)

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Application publication date: 20160302