CN106075048A - For treating the Chinese medicine composition of keratitis - Google Patents

For treating the Chinese medicine composition of keratitis Download PDF

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CN106075048A
CN106075048A CN201610680354.4A CN201610680354A CN106075048A CN 106075048 A CN106075048 A CN 106075048A CN 201610680354 A CN201610680354 A CN 201610680354A CN 106075048 A CN106075048 A CN 106075048A
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parts
radix
chinese medicine
medicine composition
keratitis
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王新华
彭剑晖
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • A61K36/195Strobilanthes
    • AHUMAN NECESSITIES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/27Asclepiadaceae (Milkweed family), e.g. hoya
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287Chrysanthemum, e.g. daisy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288Taraxacum (dandelion)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315Isatis, e.g. Dyer's woad
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/39Convolvulaceae (Morning-glory family), e.g. bindweed
    • AHUMAN NECESSITIES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/43Cuscutaceae (Dodder family), e.g. Cuscuta epithymum or greater dodder
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/482Cassia, e.g. golden shower tree
    • AHUMAN NECESSITIES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/51Gentianaceae (Gentian family)
    • A61K36/515Gentiana
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/716Clematis (leather flower)
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/79Schisandraceae (Schisandra family)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
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    • A61K36/88Liliopsida (monocotyledons)
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    • A61K36/8888Pinellia
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968Ophiopogon (Lilyturf)

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Abstract

The present invention relates to a kind of Chinese medicine composition for treating keratitis, it is characterised in that include each component of following weight portion, Radix Bupleuri 58 parts, Retinervus Luffae Fructus 15 20 parts, Herba portulacae 10 12 parts, 58 parts of Radix Dauci Sativae, Radix Isatidis 12 16 parts, Semen Cassiae 8 15 parts, Flos Lonicerae 10 20 parts, 8 20 parts of Folium Mori, Chinese clematis leaf 20 30 parts, Flos Chrysanthemi 10 20 parts etc..The invention have the advantage that have short treating period, therapeutic effect is good, to features such as human body toxic and side effects are little, it is to avoid the secondary injury that human body is caused by Western medicine;Effectively control inflammation reaction, clinical cure rate and effective percentage is good.

Description

For treating the Chinese medicine composition of keratitis
Technical field
The present invention relates to a kind of for the Chinese medicine composition for treating keratitis, belong to the field of Chinese medicines.
Background technology
Using operative therapy or the method using antiviral drugs clinically corneal inflammation, existing drawback curative effect is not more Good, relapse rate is high, the problem of drug resistance;The Western medicine used is treated, and human body produces in therapeutic process toxic and side effects, treatment Less effective.
And herpes simplex keratitis is attributed to the category of dendritic keratitis, keratomalacia by Chinese medicine, it is believed that outside primary disease mostly is Sense wind heat poison heresy or liver fire exuberance, or damp-heat in the spleen and stomach, wind-fire Shi Re Bing Pian is fought mutually, above attacks in mesh, and black eyeball is caused by burning;Also it is always or usually as specified The body deficiency of YIN, positive QI-insufficiency, feel the card of ailment said due to cold or exposure again.Wherein, the most common with liver meridian wind-heat type clinically.
Summary of the invention
For overcoming the defect of prior art, the present invention provides a kind of and uses Chinese medicine to be prepared from, the toxic and side effects to human body It is far smaller than the Chinese medicine composition of Western medicine impact.The technical scheme is that
A kind of Chinese medicine composition for treating keratitis, including each component of following weight portion, Radix Bupleuri 5-8 part, Fructus Luffae Network 15-20 part, Herba portulacae 10-12 part, Radix Dauci Sativae 5-8 part, Radix Isatidis 12-16 part, Semen Cassiae 8-15 part, Flos Lonicerae 10-20 part, Folium Mori 8-20 part, Chinese clematis leaf 20-30 part, Flos Chrysanthemi 10-20 part, Fructus Schisandrae Chinensis 10-15 part, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 8-12 part, Radix Cynanchi Paniculati 10-15 Part, Periostracum Cicadae 15-20 part, Herba Taraxaci 10-12 part, Semen Cuscutae 15-18 part, Radix Gentianae 15-20 part, Radix Ophiopogonis 8-12 part, Fructus Lycii 10-25 Part.
Preferably, Chinese medicine composition includes each component of following weight portion, Radix Bupleuri 6 parts, Retinervus Luffae Fructus 18 parts, Herba portulacae 10 Part, 7 parts of Radix Dauci Sativae, Radix Isatidis 15 parts, Semen Cassiae 10 parts, Flos Lonicerae 15 parts, 10 parts of Folium Mori, Chinese clematis leaf 25 parts, Flos Chrysanthemi 15 parts, Fructus Schisandrae Chinensis 15 parts, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 10 parts, Radix Cynanchi Paniculati 12 parts, Periostracum Cicadae 18 parts, Herba Taraxaci 10 parts, Semen Cuscutae 15 parts, Radix Gentianae 20 parts, wheat Winter 10 parts, Fructus Lycii 15 parts.
The invention have the advantage that have short treating period, therapeutic effect is good, to features such as human body toxic and side effects are little, it is to avoid west The secondary injury that human body is caused by medicine;Effectively control inflammation reaction, clinical cure rate and effective percentage is good.
Detailed description of the invention
Below in conjunction with specific embodiment further describe the present invention, advantages of the present invention and feature will be with describe and Apparent.But these embodiments are only exemplary, the scope of the present invention is not constituted any restriction.People in the art Member it should be understood that to enter the details of technical solution of the present invention and form lower without departing from the spirit and scope of the present invention Row amendment or replacement, but these amendments and replacement each fall within protection scope of the present invention.
Embodiment 1: a kind of Chinese medicine composition for treating keratitis, including each component of following weight portion, Radix Bupleuri 5g, Retinervus Luffae Fructus 15g, Herba portulacae 10g, Radix Dauci Sativae 5g, Radix Isatidis 12g, Semen Cassiae 8g, Flos Lonicerae 10g, Folium Mori 8g, Chinese clematis leaf 20g, Flos Chrysanthemi 10g, Fructus Schisandrae Chinensis 10g, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 8g, Radix Cynanchi Paniculati 10g, Periostracum Cicadae 15g, Herba Taraxaci 10g, Semen Cuscutae 15g, Radix Gentianae 15g, wheat Winter 8g, Fructus Lycii 10g.
Embodiment 2: a kind of Chinese medicine composition for treating keratitis, including each component of following weight portion, Radix Bupleuri 6g, Retinervus Luffae Fructus 18g, Herba portulacae 10g, Radix Dauci Sativae 7g, Radix Isatidis 15g, Semen Cassiae 10g, Flos Lonicerae 15g, Folium Mori 10g, Chinese clematis leaf 25g, Flos Chrysanthemi 15g, Fructus Schisandrae Chinensis 15g, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 10g, Radix Cynanchi Paniculati 12g, Periostracum Cicadae 18g, Herba Taraxaci 10g, Semen Cuscutae 15g, Radix Gentianae 20g, Radix Ophiopogonis 10g, Fructus Lycii 15g.
Embodiment 3: a kind of Chinese medicine composition for treating keratitis, including each component of following weight portion, Radix Bupleuri 8g, Retinervus Luffae Fructus 20g, Herba portulacae 12g, Radix Dauci Sativae 8g, Radix Isatidis 16g, Semen Cassiae 15g, Flos Lonicerae 20g, Folium Mori 20g, Chinese clematis leaf 30g, Flos Chrysanthemi 20g, Fructus Schisandrae Chinensis 15g, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 12g, Radix Cynanchi Paniculati 15g, Periostracum Cicadae 20g, Herba Taraxaci 12g, Semen Cuscutae 18g, Radix Gentianae 20g, Radix Ophiopogonis 12g, Fructus Lycii 25g.
1.1 diagnostic criterias: carry out clinical diagnosis with reference to the diagnosis basis in " Chinese medical disease Standardization of diagnosis and curative effect ": cornea Edge glue sample tuberosity;More eosinophilic granulocyte and the eosinophilic granulocyte's tuberosity being dispersed in conjunctival secretion;Slight ciliary congestion, Main feel photophobia, foreign body sensation, form vesicle then, and blister ruptures rapidly, and is interconnected to form tree-shaped table fester.Pain Bitterly, the symptom aggravation of photophobia, blepharospasm.
1.2 therapeutic outcomes:
Treatment evaluation criteria, judges according to " the Chinese medical disease Standardization of diagnosis and curative effect " that State Administration of Traditional Chinese Medicine formulates:
Curing: clinical symptoms and sign all disappear, vision restoration is normal (or vision restoration is to premorbid vision);
Effective: irritation is wholly absent, conjunctival congestion disappears, and cornea recovers transparent, eugnosia, and vision improves, faces Bed symptom and sign all disappear;
Effective: irritation disappears substantially, conjunctival congestion is gone down, and cornea recovers transparent substantially, the normal clinic of consciousness Symptom and sign all disappear or partial disappearance or improvement, and vision is without improving;
Invalid: vision is without improving or clinical symptoms and sign are without taking a turn for the better or increasing the weight of.
1.3 results: in 100 example patients, cure 68 examples, effective 23 examples, effective 5 examples, invalid 4 examples, and total effective rate is 96%.
Model case
1, Chen, man, 21 years old, right eye was very itched, more than 3 years medical histories.Red tongue.Check: vision: right eye 0.8, left eye 0.5, examine as keratoconjunctivitis.Take the Chinese medicine composition of the present invention, take after decocting, every day potion, twice decoction being taken warmly sooner or later.Clothes After 1 course for the treatment of of medicine, patient condition removes to the greatest extent.For consolidating curative effect, advise it to take again and consolidated 1 course for the treatment of, keep in dark place, symptom of shedding tears disappears Remove.Follow up a case by regular visits to after 1 year, have no recurrence.
2, ten thousand certain, female, 31 years old, eyes felt there is foreign body, itch, existing with headache, heating.Check: binocular vision is 1.0, palpebral conjunctiva is congested substantially, takes 1 course for the treatment of of medicine of the present invention, every day 2 doses, transference cure, follows up a case by regular visits to without recurrence after 1 year.

Claims (2)

1. for treating the Chinese medicine composition of keratitis, it is characterised in that include each component of following weight portion, Radix Bupleuri 5-8 part, Retinervus Luffae Fructus 15-20 part, Herba portulacae 10-12 part, Radix Dauci Sativae 5-8 part, Radix Isatidis 12-16 part, Semen Cassiae 8-15 part, Flos Lonicerae 10-20 Part, Folium Mori 8-20 part, Chinese clematis leaf 20-30 part, Flos Chrysanthemi 10-20 part, Fructus Schisandrae Chinensis 10-15 part, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 8-12 part, Radix Cynanchi Paniculati 10-15 part, Periostracum Cicadae 15-20 part, Herba Taraxaci 10-12 part, Semen Cuscutae 15-18 part, Radix Gentianae 15-20 part, Radix Ophiopogonis 8-12 part, Fructus Lycii 10-25 part.
Chinese medicine composition for treating keratitis the most according to claim 1, it is characterised in that include following weight portion Each component, Radix Bupleuri 6 parts, Retinervus Luffae Fructus 18 parts, Herba portulacae 10 parts, 7 parts of Radix Dauci Sativae, Radix Isatidis 15 parts, Semen Cassiae 10 parts, Flos Lonicerae 15 parts, 10 parts of Folium Mori, Chinese clematis leaf 25 parts, Flos Chrysanthemi 15 parts, Fructus Schisandrae Chinensis 15 parts, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 10 parts, Radix Cynanchi Paniculati 12 parts, Periostracum Cicadae 18 Part, Herba Taraxaci 10 parts, Semen Cuscutae 15 parts, Radix Gentianae 20 parts, Radix Ophiopogonis 10 parts, Fructus Lycii 15 parts.
CN201610680354.4A 2016-08-17 2016-08-17 For treating the Chinese medicine composition of keratitis Pending CN106075048A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102579991A (en) * 2012-03-03 2012-07-18 丁磊 Chinese medicinal inflammation diminishing preparation for treating herpes simplex keratitis
CN103800485A (en) * 2014-03-12 2014-05-21 马丽 Traditional Chinese medicine preparation for treating herpes simplex keratitis
CN104873581A (en) * 2015-06-09 2015-09-02 张玉芳 Traditional Chinese medicine for treating herpes simplex keratitis
CN104887996A (en) * 2015-05-16 2015-09-09 陈久洲 Traditional Chinese medicine decoction for treating acute conjunctivitis

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102579991A (en) * 2012-03-03 2012-07-18 丁磊 Chinese medicinal inflammation diminishing preparation for treating herpes simplex keratitis
CN103800485A (en) * 2014-03-12 2014-05-21 马丽 Traditional Chinese medicine preparation for treating herpes simplex keratitis
CN104887996A (en) * 2015-05-16 2015-09-09 陈久洲 Traditional Chinese medicine decoction for treating acute conjunctivitis
CN104873581A (en) * 2015-06-09 2015-09-02 张玉芳 Traditional Chinese medicine for treating herpes simplex keratitis

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