CN103783515A - Angelica sinensis-rhizoma dioscoreae dispersible tablets and preparation method thereof - Google Patents
Angelica sinensis-rhizoma dioscoreae dispersible tablets and preparation method thereof Download PDFInfo
- Publication number
- CN103783515A CN103783515A CN201310748527.8A CN201310748527A CN103783515A CN 103783515 A CN103783515 A CN 103783515A CN 201310748527 A CN201310748527 A CN 201310748527A CN 103783515 A CN103783515 A CN 103783515A
- Authority
- CN
- China
- Prior art keywords
- parts
- radix angelicae
- angelicae sinensis
- chinese yam
- vitamin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 235000001287 Guettarda speciosa Nutrition 0.000 title claims abstract description 15
- 238000002360 preparation method Methods 0.000 title claims description 11
- 244000061520 Angelica archangelica Species 0.000 title claims 4
- 239000007919 dispersible tablet Substances 0.000 title abstract 3
- 239000000843 powder Substances 0.000 claims abstract description 35
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims abstract description 26
- 239000008213 purified water Substances 0.000 claims abstract description 22
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 22
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract description 18
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims abstract description 18
- DKKCQDROTDCQOR-UHFFFAOYSA-L Ferrous lactate Chemical compound [Fe+2].CC(O)C([O-])=O.CC(O)C([O-])=O DKKCQDROTDCQOR-UHFFFAOYSA-L 0.000 claims abstract description 18
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims abstract description 18
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims abstract description 18
- 229920002472 Starch Polymers 0.000 claims abstract description 18
- 241000222355 Trametes versicolor Species 0.000 claims abstract description 18
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims abstract description 18
- 239000004225 ferrous lactate Substances 0.000 claims abstract description 18
- 229940037907 ferrous lactate Drugs 0.000 claims abstract description 18
- 235000013925 ferrous lactate Nutrition 0.000 claims abstract description 18
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims abstract description 18
- 239000011734 sodium Substances 0.000 claims abstract description 18
- 229910052708 sodium Inorganic materials 0.000 claims abstract description 18
- 235000019698 starch Nutrition 0.000 claims abstract description 18
- 235000019408 sucralose Nutrition 0.000 claims abstract description 18
- 239000004376 Sucralose Substances 0.000 claims abstract description 13
- 229930003427 Vitamin E Natural products 0.000 claims abstract description 13
- 239000001768 carboxy methyl cellulose Substances 0.000 claims abstract description 13
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims abstract description 13
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims abstract description 13
- 239000008108 microcrystalline cellulose Substances 0.000 claims abstract description 13
- 229940016286 microcrystalline cellulose Drugs 0.000 claims abstract description 13
- 239000008107 starch Substances 0.000 claims abstract description 13
- BAQAVOSOZGMPRM-QBMZZYIRSA-N sucralose Chemical compound O[C@@H]1[C@@H](O)[C@@H](Cl)[C@@H](CO)O[C@@H]1O[C@@]1(CCl)[C@@H](O)[C@H](O)[C@@H](CCl)O1 BAQAVOSOZGMPRM-QBMZZYIRSA-N 0.000 claims abstract description 13
- 235000019165 vitamin E Nutrition 0.000 claims abstract description 13
- 229940046009 vitamin E Drugs 0.000 claims abstract description 13
- 239000011709 vitamin E Substances 0.000 claims abstract description 13
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims abstract description 9
- 229930003268 Vitamin C Natural products 0.000 claims abstract description 9
- 235000019154 vitamin C Nutrition 0.000 claims abstract description 9
- 239000011718 vitamin C Substances 0.000 claims abstract description 9
- 235000002722 Dioscorea batatas Nutrition 0.000 claims description 50
- 235000006536 Dioscorea esculenta Nutrition 0.000 claims description 50
- 240000001811 Dioscorea oppositifolia Species 0.000 claims description 50
- 235000003416 Dioscorea oppositifolia Nutrition 0.000 claims description 50
- 239000000203 mixture Substances 0.000 claims description 27
- 235000009508 confectionery Nutrition 0.000 claims description 17
- 239000000741 silica gel Substances 0.000 claims description 17
- 229910002027 silica gel Inorganic materials 0.000 claims description 17
- 239000000706 filtrate Substances 0.000 claims description 14
- 230000001954 sterilising effect Effects 0.000 claims description 14
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 claims description 12
- 239000002002 slurry Substances 0.000 claims description 12
- 238000001238 wet grinding Methods 0.000 claims description 12
- 239000002245 particle Substances 0.000 claims description 10
- 239000000835 fiber Substances 0.000 claims description 7
- 238000000227 grinding Methods 0.000 claims description 7
- 238000010438 heat treatment Methods 0.000 claims description 7
- 239000002994 raw material Substances 0.000 claims description 7
- 238000002791 soaking Methods 0.000 claims description 7
- 238000004659 sterilization and disinfection Methods 0.000 claims description 7
- 238000000605 extraction Methods 0.000 claims description 6
- 238000001914 filtration Methods 0.000 claims description 6
- PTHCMJGKKRQCBF-UHFFFAOYSA-N Cellulose, microcrystalline Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC)C(CO)O1 PTHCMJGKKRQCBF-UHFFFAOYSA-N 0.000 claims description 5
- 235000004879 dioscorea Nutrition 0.000 claims description 5
- 238000005469 granulation Methods 0.000 claims description 5
- 230000003179 granulation Effects 0.000 claims description 5
- 238000002156 mixing Methods 0.000 claims description 5
- 238000010298 pulverizing process Methods 0.000 claims description 5
- 238000007873 sieving Methods 0.000 claims description 5
- 238000003756 stirring Methods 0.000 claims description 5
- 229930003231 vitamin Natural products 0.000 claims description 4
- 235000013343 vitamin Nutrition 0.000 claims description 4
- 239000011782 vitamin Substances 0.000 claims description 4
- 229940088594 vitamin Drugs 0.000 claims description 4
- 150000003722 vitamin derivatives Chemical class 0.000 claims description 4
- 241000125175 Angelica Species 0.000 abstract description 11
- 239000008280 blood Substances 0.000 abstract description 4
- 210000004369 blood Anatomy 0.000 abstract description 4
- 208000007502 anemia Diseases 0.000 abstract description 3
- 235000013336 milk Nutrition 0.000 abstract description 3
- 239000008267 milk Substances 0.000 abstract description 3
- 210000004080 milk Anatomy 0.000 abstract description 3
- 230000007812 deficiency Effects 0.000 abstract description 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 abstract 2
- 229910002012 Aerosil® Inorganic materials 0.000 abstract 1
- 241000382455 Angelica sinensis Species 0.000 abstract 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 abstract 1
- 229930195725 Mannitol Natural products 0.000 abstract 1
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 235000019359 magnesium stearate Nutrition 0.000 abstract 1
- 239000000594 mannitol Substances 0.000 abstract 1
- 235000010355 mannitol Nutrition 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 235000010755 mineral Nutrition 0.000 abstract 1
- 238000011084 recovery Methods 0.000 abstract 1
- 238000005728 strengthening Methods 0.000 abstract 1
- 208000019395 Lactation disease Diseases 0.000 description 4
- 206010042576 Suppressed lactation Diseases 0.000 description 4
- 210000000481 breast Anatomy 0.000 description 3
- 230000037006 agalactosis Effects 0.000 description 2
- 230000037182 bone density Effects 0.000 description 2
- 235000005911 diet Nutrition 0.000 description 2
- 230000000378 dietary effect Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 230000000153 supplemental effect Effects 0.000 description 2
- 206010033557 Palpitations Diseases 0.000 description 1
- 208000009205 Tinnitus Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 235000013402 health food Nutrition 0.000 description 1
- 230000006651 lactation Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 231100000886 tinnitus Toxicity 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/20—Agglomerating; Granulating; Tabletting
- A23P10/28—Tabletting; Making food bars by compression of a dry powdered mixture
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Botany (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
Claims (5)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201310748527.8A CN103783515B (en) | 2013-12-31 | 2013-12-31 | A kind of Radix Angelicae Sinensis Chinese yam dispersible tablet and preparation method |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201310748527.8A CN103783515B (en) | 2013-12-31 | 2013-12-31 | A kind of Radix Angelicae Sinensis Chinese yam dispersible tablet and preparation method |
Publications (2)
Publication Number | Publication Date |
---|---|
CN103783515A true CN103783515A (en) | 2014-05-14 |
CN103783515B CN103783515B (en) | 2015-11-18 |
Family
ID=50659901
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201310748527.8A Expired - Fee Related CN103783515B (en) | 2013-12-31 | 2013-12-31 | A kind of Radix Angelicae Sinensis Chinese yam dispersible tablet and preparation method |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN103783515B (en) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1481211B1 (en) * | 2001-11-29 | 2009-04-22 | J. Rettenmaier & Söhne GmbH + Co. KG | Process for co-spray drying liquid herbal extracts with dry silicified mcc |
CN102113669A (en) * | 2009-12-30 | 2011-07-06 | 徐德连 | Green health-care noodles for puerpera lactation promotion |
CN103142805A (en) * | 2013-03-07 | 2013-06-12 | 尹喜玲 | Traditional Chinese medicine composite for treating puerpera hypogalactia |
-
2013
- 2013-12-31 CN CN201310748527.8A patent/CN103783515B/en not_active Expired - Fee Related
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1481211B1 (en) * | 2001-11-29 | 2009-04-22 | J. Rettenmaier & Söhne GmbH + Co. KG | Process for co-spray drying liquid herbal extracts with dry silicified mcc |
CN102113669A (en) * | 2009-12-30 | 2011-07-06 | 徐德连 | Green health-care noodles for puerpera lactation promotion |
CN103142805A (en) * | 2013-03-07 | 2013-06-12 | 尹喜玲 | Traditional Chinese medicine composite for treating puerpera hypogalactia |
Non-Patent Citations (2)
Title |
---|
刘敏如,等: "《世界传统医学妇科学》", 31 January 1999 * |
白洁,等: "当归分散片处方与直接压片工艺的研究", 《医药导报》 * |
Also Published As
Publication number | Publication date |
---|---|
CN103783515B (en) | 2015-11-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C41 | Transfer of patent application or patent right or utility model | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20150928 Address after: 523000 Guangdong city of Dongguan province Dongcheng District Dongcheng style Pedestrian Street No. C25 Applicant after: Chen Huishan Address before: 523120, 702, room 1, Peony Pavilion, Dongcheng business garden, Dongguan, Guangdong, Dongcheng District Applicant before: Chen Huiting |
|
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
CB03 | Change of inventor or designer information | ||
CB03 | Change of inventor or designer information |
Inventor after: Liu Guihua Inventor before: Chen Huiting |
|
TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20170605 Address after: 225401, Suzhou City, Jiangsu province 138 North Road, Taixing City, East Wholesale City Patentee after: Liu Guihua Address before: 523000 Guangdong city of Dongguan province Dongcheng District Dongcheng style Pedestrian Street No. C25 Patentee before: Chen Huishan |
|
CB03 | Change of inventor or designer information | ||
CB03 | Change of inventor or designer information |
Inventor after: Zhang Lijuan Inventor after: Zhang Lingli Inventor before: Liu Guihua |
|
TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20170821 Address after: 457001 No. 5, building 24, building 232, Shengli East Road, Hualong District, Henan, Puyang, 10 Co-patentee after: Zhang Lingli Patentee after: Zhang Lijuan Address before: 225401, Suzhou City, Jiangsu province 138 North Road, Taixing City, East Wholesale City Patentee before: Liu Guihua |
|
TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20180611 Address after: 518100 Longgang District, Longgang District, Shenzhen, Guangdong Province, south part of the community joint industrial zone 1-1 Patentee after: Shenzhen Zhenghuangzhuang Prepared Chinese Herbal Medicine Co., Ltd. Address before: 457001 10 unit 5, 24 building, 232 Shengli East Road, Hualong District, Puyang, Henan. Co-patentee before: Zhang Lingli Patentee before: Zhang Lijuan |
|
CF01 | Termination of patent right due to non-payment of annual fee | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20151118 Termination date: 20191231 |