CN103704709B - Dispersible tablet of codonopsis pilosula and bergamot and preparation method of dispersible tablet - Google Patents
Dispersible tablet of codonopsis pilosula and bergamot and preparation method of dispersible tablet Download PDFInfo
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- 235000010672 Monarda didyma Nutrition 0.000 title claims abstract description 36
- 238000002360 preparation method Methods 0.000 title claims description 10
- 239000007919 dispersible tablet Substances 0.000 title abstract 7
- 241000007126 Codonopsis pilosula Species 0.000 title abstract 3
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims abstract description 34
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- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract description 24
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims abstract description 18
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims abstract description 17
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims abstract description 17
- 229920002472 Starch Polymers 0.000 claims abstract description 17
- 239000004376 Sucralose Substances 0.000 claims abstract description 17
- 241000222355 Trametes versicolor Species 0.000 claims abstract description 17
- 229910000019 calcium carbonate Inorganic materials 0.000 claims abstract description 17
- 239000001768 carboxy methyl cellulose Substances 0.000 claims abstract description 17
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims abstract description 17
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims abstract description 17
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims abstract description 17
- 239000008108 microcrystalline cellulose Substances 0.000 claims abstract description 17
- 229940016286 microcrystalline cellulose Drugs 0.000 claims abstract description 17
- 239000000843 powder Substances 0.000 claims abstract description 17
- 239000011734 sodium Substances 0.000 claims abstract description 17
- 229910052708 sodium Inorganic materials 0.000 claims abstract description 17
- 239000008107 starch Substances 0.000 claims abstract description 17
- 235000019698 starch Nutrition 0.000 claims abstract description 17
- BAQAVOSOZGMPRM-QBMZZYIRSA-N sucralose Chemical compound O[C@@H]1[C@@H](O)[C@@H](Cl)[C@@H](CO)O[C@@H]1O[C@@]1(CCl)[C@@H](O)[C@H](O)[C@@H](CCl)O1 BAQAVOSOZGMPRM-QBMZZYIRSA-N 0.000 claims abstract description 17
- 235000019408 sucralose Nutrition 0.000 claims abstract description 17
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims abstract description 12
- 229930003268 Vitamin C Natural products 0.000 claims abstract description 12
- 235000019154 vitamin C Nutrition 0.000 claims abstract description 12
- 239000011718 vitamin C Substances 0.000 claims abstract description 12
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 35
- 241000756943 Codonopsis Species 0.000 claims description 33
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 21
- 238000010298 pulverizing process Methods 0.000 claims description 17
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 claims description 16
- 235000009508 confectionery Nutrition 0.000 claims description 16
- 239000000203 mixture Substances 0.000 claims description 16
- 239000000741 silica gel Substances 0.000 claims description 16
- 229910002027 silica gel Inorganic materials 0.000 claims description 16
- 239000002245 particle Substances 0.000 claims description 15
- 239000002994 raw material Substances 0.000 claims description 15
- 239000000706 filtrate Substances 0.000 claims description 14
- 239000002002 slurry Substances 0.000 claims description 14
- 235000004879 dioscorea Nutrition 0.000 claims description 12
- 235000013312 flour Nutrition 0.000 claims description 12
- 206010033546 Pallor Diseases 0.000 claims description 7
- 238000009835 boiling Methods 0.000 claims description 7
- 238000001035 drying Methods 0.000 claims description 7
- 238000000605 extraction Methods 0.000 claims description 7
- 230000001954 sterilising effect Effects 0.000 claims description 7
- 238000004659 sterilization and disinfection Methods 0.000 claims description 7
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- PTHCMJGKKRQCBF-UHFFFAOYSA-N Cellulose, microcrystalline Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC)C(CO)O1 PTHCMJGKKRQCBF-UHFFFAOYSA-N 0.000 claims description 5
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- 208000004998 Abdominal Pain Diseases 0.000 abstract description 7
- 210000001015 abdomen Anatomy 0.000 abstract description 6
- 230000000694 effects Effects 0.000 abstract description 3
- 208000009205 Tinnitus Diseases 0.000 abstract description 2
- 208000002173 dizziness Diseases 0.000 abstract description 2
- 231100000886 tinnitus Toxicity 0.000 abstract description 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 abstract 2
- 241000213006 Angelica dahurica Species 0.000 abstract 1
- 229920001661 Chitosan Polymers 0.000 abstract 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 abstract 1
- 229930195725 Mannitol Natural products 0.000 abstract 1
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 230000036039 immunity Effects 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 235000019359 magnesium stearate Nutrition 0.000 abstract 1
- 239000000594 mannitol Substances 0.000 abstract 1
- 235000010355 mannitol Nutrition 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 239000000377 silicon dioxide Substances 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 7
- 201000010099 disease Diseases 0.000 description 6
- 239000004615 ingredient Substances 0.000 description 5
- 208000032843 Hemorrhage Diseases 0.000 description 3
- 235000005911 diet Nutrition 0.000 description 3
- 230000000740 bleeding effect Effects 0.000 description 2
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- 238000005516 engineering process Methods 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 210000004291 uterus Anatomy 0.000 description 2
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- 208000021129 Postpartum disease Diseases 0.000 description 1
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- 230000002159 abnormal effect Effects 0.000 description 1
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- 230000035606 childbirth Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
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- 230000001771 impaired effect Effects 0.000 description 1
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- 210000004185 liver Anatomy 0.000 description 1
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- 210000000056 organ Anatomy 0.000 description 1
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- 238000004080 punching Methods 0.000 description 1
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- 238000002560 therapeutic procedure Methods 0.000 description 1
- 229940126672 traditional medicines Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L19/00—Products from fruits or vegetables; Preparation or treatment thereof
- A23L19/01—Instant products; Powders; Flakes; Granules
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L19/00—Products from fruits or vegetables; Preparation or treatment thereof
- A23L19/10—Products from fruits or vegetables; Preparation or treatment thereof of tuberous or like starch containing root crops
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/20—Agglomerating; Granulating; Tabletting
- A23P10/28—Tabletting; Making food bars by compression of a dry powdered mixture
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The invention discloses a dispersible tablet of codonopsis pilosula and bergamot. The dispersible tablet comprises the following components in parts by weight: 200-300 parts of Chinese yam, 200-300 parts of Chinese angelica, 200-300 parts of the codonopsis pilosula, 100-200 pats of the bergamot, 40-60 parts of microcrystalline cellulose, 0.12-0.32 part of trametes versicolor extract, 0.12-0.32 chitosan, 1-2 parts of vitamin C, 0.1-0.2 part of calcium carbonate, 100-170 parts of mannitol, 10-15 parts of sucralose, 10-50 parts of superfine silica powder, 3-5 parts of carboxymethylcellulose, 55-80 parts of sodium carboxymethyl starch, and 4-6 parts of magnesium stearate. The dispersible tablet has the effects of enriching blood and replenishing qi, increasing the bone mineral density, enhancing the immunity and the like. The dispersible tablet is suitable for postpartum abdominal pain, and the symptoms include gripping pain of the lower abdomen, comfortable feeling when the lower abdomen is pressed, little and light lochia, dizziness, tinnitus, fence dregs, pink tongue, thin fur and the like; the dispersible tablet is used for auxiliary rehabilitation.
Description
Technical field
The invention belongs to nutritional health food field, be specially a kind of Radix Codonopsis bergamot dispersing tablet and preparation method.
Background technology
Postpartum abdominal pain be puerpera within puerperium, occur with give a birth or mix relevant underbelly pain.After pregnant woman childbirth, due to the retraction effect in uterus, underbelly is a burst ofly to have a pain, in postpartum l, within 2nd, occur, continue Lock-out on the 2nd, 3, western medicine claims " uterine contraction pain ", " afterpains ", belong to physiological phenomenon, one does not need treatment.The a burst of aggravation if suffer from abdominal pain, is difficult to stand, or continuous and dull pain in the abdomen, and pain is not own, affects perinatal health, be then morbid state, should treat.Postpartum abdominal pain is that the underbelly pelvic organs of women is more, when occurring abnormal, easily causes postpartum abdominal pain, comprises stomachache and the pain of lower abdomen, the most common with lower abdomen pain.Postpartum abdominal pain can because of deficiency of blood physique, or excessive blood loss when producing, and punching is appointed hollow, and vessels of the uterus loses supports, or deficient qi and blood, and fortune blood is unable, thrombosis, sluggish and pain; Also can be careless because of daily life in postpartum, cold-evil takes advantage of a weak point, or diet raw food, and blood is for cold solidifying, or postpartum, feelings were smooth, stagnation of liver qi qi depression to blood stasis, or lochia drainage difficulty and causing.Women's postpartum disease is common disease and the frequently-occurring disease of gynaecology, is that harm body of women is healthy, even life-threatening important diseases.The traditional Chinese medical science is thought, postpartum women Massive Bleeding, and hinder Tianjin hemorrhage bleeding, blood-stasis internal-depression, disorder of qi, vigour is impaired, and the turbid liquid of remaining blood to the greatest extent, does not easily occur various diseases.Although also have Chinese Traditional Medicines or the formula of a lot of postpartum women disease at present, although treatment prescribed preparation is a lot, be all occur with the form of medicine, the dietary product being applicable to long-term edible supplemental treatment is little.Therefore the dietary product researching and developing a kind of safe adjunct therapy is very with practical value.
Summary of the invention
For above-mentioned situation, technical problem solved by the invention is to provide a kind of blood yiqi, increases the preparation method of Radix Codonopsis bergamot dispersing tablet of bone density, develop immunitypty, to solve the problem proposed in above-mentioned background technology.
For achieving the above object, the invention provides following technical scheme:
A kind of Radix Codonopsis bergamot dispersing tablet, comprises following parts by weight ingredient: Chinese yam 200-300 part, Radix Angelicae Sinensis 200-300 part, Radix Codonopsis 200-300 part, bergamot 100-200 part, microcrystalline cellulose 40-60 part, Coriolus Versicolor P.E. 0.12-0.32 part, shitosan 0.12-0.32 part, vitamin C 1-2 part, calcium carbonate 0.1-0.2 part, sweet mellow wine 100-170 part, Sucralose 10-15 part, superfine silica gel powder 10-50 part, carboxymethyl cellulose 3-5 part, sodium carboxymethyl starch 55-80 part, dolomol 4-6 part.
As preferably, described a kind of Radix Codonopsis bergamot dispersing tablet, comprises following parts by weight ingredient: Chinese yam 250 parts, Radix Angelicae Sinensis 250 parts, Radix Codonopsis 250 parts, bergamot 150 parts, microcrystalline cellulose 50 parts, Coriolus Versicolor P.E. 0.22 part, shitosan 0.22 part, vitamin C 1.5 parts, 0.15 part, calcium carbonate, 135 parts, sweet mellow wine, Sucralose 12.5 parts, superfine silica gel powder 30 parts, carboxymethyl cellulose 4 parts, sodium carboxymethyl starch 67.5 parts, dolomol 5 parts.
A preparation method for Radix Codonopsis bergamot dispersing tablet, comprises the following steps:
(1) get fresh Chinese yam to clean, peeling, stripping and slicing, put into boiling water blanching 3-5min, control water is placed in bruisher and is pounded thick slurry, will smash rear thick slurry temperature to pieces and control as within the scope of 60-65 DEG C, time is that 0.5-2h is dried, Chinese yam after drying is pulverized, crosses 80-100 mesh sieve, the Chinese yam after pulverizing is carried out high temperature instantaneous sterilization, temperature controls as within the scope of 115-120 DEG C, time is 5-10s, obtains yam flour, for subsequent use;
(2) get raw material Radix Angelicae Sinensis, Radix Codonopsis, bergamot clean, soak 1-3h, decoct extraction 3 times, each 1h, amount of water is raw material gross mass 8-10 times amount doubly, filters, merging filtrate, when filtrate is concentrated into 50 DEG C, relative density is the medicinal extract of 1.05-1.10, adding ethanol makes alcohol content be 60-75%, leaves standstill 12-24h, gets supernatant, reclaim ethanol and be concentrated into the thick paste of relative density 1.15-1.25, for subsequent use;
(3) get microcrystalline cellulose, Coriolus Versicolor P.E., shitosan, calcium carbonate, sweet mellow wine, Sucralose, superfine silica gel powder, carboxymethyl cellulose, sodium carboxymethyl starch, dolomol pulverize respectively, cross 100-150 mesh sieve, for subsequent use;
(4) thick paste that yam flour obtained for step (1), step (2) obtain is uniformly mixed, in mixture, add carboxymethyl cellulose, microcrystalline cellulose, Coriolus Versicolor P.E., shitosan, calcium carbonate, sweet mellow wine, Sucralose, superfine silica gel powder, sodium carboxymethyl starch after pulverizing in vitamin C and above-mentioned steps stir, mixer rotating speed is 10-20r/min, time is 10-20min, obtains mixture for subsequent use;
(5) mixture that step (4) is obtained is carried out making particle, particle is dried 1-5h within the scope of 30-45 DEG C, cross 20-40 mesh sieve;
(6) particle after sieving is added the dolomol mixing machine after pulverizing to mix, rotating speed is 10-15r/min, and the time is 6-8min, then carries out compressing tablet, obtains Radix Codonopsis bergamot dispersing tablet.
Get fresh Chinese yam in described step (1) to clean, peeling, stripping and slicing, put into boiling water blanching 5min, control water is placed in bruisher and is pounded thick slurry, and will smash rear thick slurry temperature to pieces and control to be under 60 DEG C of conditions, the time is that 2h is dried, Chinese yam after drying is pulverized, cross 100 mesh sieves, the Chinese yam after pulverizing is carried out high temperature instantaneous sterilization, and it is within the scope of 115 DEG C that temperature controls, time is 10s, obtains yam flour.
Get in described step (2) raw material Radix Angelicae Sinensis, Radix Codonopsis, bergamot clean, soak 1h, decoct extraction 3 times, each 1h, amount of water is raw material gross mass 8 times amount doubly, filter, merging filtrate, when filtrate is concentrated into 50 DEG C, relative density is the medicinal extract of 1.05, adding ethanol makes alcohol content be 60%, leave standstill 24h, get supernatant, reclaim ethanol and be concentrated into the thick paste of relative density 1.25.
In sum, beneficial effect of the present invention:
The present invention has blood yiqi, increases the effect such as bone density, develop immunitypty.Be applicable to postpartum abdominal pain, disease sees that underbelly has a dull ache, belly happiness is light by, the few sunlight of lochia amount, dizziness and tinnitus, just grain, pink tongue, tongue are thin, for recovering aid.
Detailed description of the invention
Below in conjunction with the embodiment of the present invention, be clearly and completely described the technical scheme in the embodiment of the present invention, obviously, described embodiment is only the present invention's part embodiment, instead of whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtained under creative work prerequisite, belong to the scope of protection of the invention.
Embodiment 1
A kind of Radix Codonopsis bergamot dispersing tablet, comprises following parts by weight ingredient: Chinese yam 200 parts, Radix Angelicae Sinensis 200 parts, Radix Codonopsis 200 parts, bergamot 100 parts, microcrystalline cellulose 40 parts, Coriolus Versicolor P.E. 0.12 part, shitosan 0.12 part, vitamin C 1 part, 0.1 part, calcium carbonate, 100 parts, sweet mellow wine, Sucralose 10 parts, superfine silica gel powder 10 parts, carboxymethyl cellulose 3 parts, sodium carboxymethyl starch 55 parts, dolomol 4 parts.
A preparation method for Radix Codonopsis bergamot dispersing tablet, comprises the following steps:
(1) get fresh Chinese yam to clean, peeling, stripping and slicing, put into boiling water blanching 3-5min, control water is placed in bruisher and is pounded thick slurry, will smash rear thick slurry temperature to pieces and control as within the scope of 60-65 DEG C, time is that 0.5-2h is dried, Chinese yam after drying is pulverized, crosses 80-100 mesh sieve, the Chinese yam after pulverizing is carried out high temperature instantaneous sterilization, temperature controls as within the scope of 115-120 DEG C, time is 5-10s, obtains yam flour, for subsequent use;
(2) get raw material Radix Angelicae Sinensis, Radix Codonopsis, bergamot clean, soak 1-3h, decoct extraction 3 times, each 1h, amount of water is raw material gross mass 8-10 times amount doubly, filters, merging filtrate, when filtrate is concentrated into 50 DEG C, relative density is the medicinal extract of 1.05-1.10, adding ethanol makes alcohol content be 60-75%, leaves standstill 12-24h, gets supernatant, reclaim ethanol and be concentrated into the thick paste of relative density 1.15-1.25, for subsequent use;
(3) get microcrystalline cellulose, Coriolus Versicolor P.E., shitosan, calcium carbonate, sweet mellow wine, Sucralose, superfine silica gel powder, carboxymethyl cellulose, sodium carboxymethyl starch, dolomol pulverize respectively, cross 100-150 mesh sieve, for subsequent use;
(4) thick paste that yam flour obtained for step (1), step (2) obtain is uniformly mixed, in mixture, add carboxymethyl cellulose, microcrystalline cellulose, Coriolus Versicolor P.E., shitosan, calcium carbonate, sweet mellow wine, Sucralose, superfine silica gel powder, sodium carboxymethyl starch after pulverizing in vitamin C and above-mentioned steps stir, mixer rotating speed is 10-20r/min, time is 10-20min, obtains mixture for subsequent use;
(5) mixture that step (4) is obtained is carried out making particle, particle is dried 1-5h within the scope of 30-45 DEG C, cross 20-40 mesh sieve;
(6) particle after sieving is added the dolomol mixing machine after pulverizing to mix, rotating speed is 10-15r/min, and the time is 6-8min, then carries out compressing tablet, obtains Radix Codonopsis bergamot dispersing tablet.
Embodiment 2
A kind of Radix Codonopsis bergamot dispersing tablet, comprises following parts by weight ingredient: Chinese yam 250 parts, Radix Angelicae Sinensis 250 parts, Radix Codonopsis 250 parts, bergamot 150 parts, microcrystalline cellulose 50 parts, Coriolus Versicolor P.E. 0.22 part, shitosan 0.22 part, vitamin C 1.5 parts, 0.15 part, calcium carbonate, 135 parts, sweet mellow wine, Sucralose 12.5 parts, superfine silica gel powder 30 parts, carboxymethyl cellulose 4 parts, sodium carboxymethyl starch 67.5 parts, dolomol 5 parts.
A preparation method for Radix Codonopsis bergamot dispersing tablet, comprises the following steps:
(1) get fresh Chinese yam to clean, peeling, stripping and slicing, put into boiling water blanching 3-5min, control water is placed in bruisher and is pounded thick slurry, will smash rear thick slurry temperature to pieces and control as within the scope of 60-65 DEG C, time is that 0.5-2h is dried, Chinese yam after drying is pulverized, crosses 80-100 mesh sieve, the Chinese yam after pulverizing is carried out high temperature instantaneous sterilization, temperature controls as within the scope of 115-120 DEG C, time is 5-10s, obtains yam flour, for subsequent use;
(2) get raw material Radix Angelicae Sinensis, Radix Codonopsis, bergamot clean, soak 1-3h, decoct extraction 3 times, each 1h, amount of water is raw material gross mass 8-10 times amount doubly, filters, merging filtrate, when filtrate is concentrated into 50 DEG C, relative density is the medicinal extract of 1.05-1.10, adding ethanol makes alcohol content be 60-75%, leaves standstill 12-24h, gets supernatant, reclaim ethanol and be concentrated into the thick paste of relative density 1.15-1.25, for subsequent use;
(3) get microcrystalline cellulose, Coriolus Versicolor P.E., shitosan, calcium carbonate, sweet mellow wine, Sucralose, superfine silica gel powder, carboxymethyl cellulose, sodium carboxymethyl starch, dolomol pulverize respectively, cross 100-150 mesh sieve, for subsequent use;
(4) thick paste that yam flour obtained for step (1), step (2) obtain is uniformly mixed, in mixture, add carboxymethyl cellulose, microcrystalline cellulose, Coriolus Versicolor P.E., shitosan, calcium carbonate, sweet mellow wine, Sucralose, superfine silica gel powder, sodium carboxymethyl starch after pulverizing in vitamin C and above-mentioned steps stir, mixer rotating speed is 10-20r/min, time is 10-20min, obtains mixture for subsequent use;
(5) mixture that step (4) is obtained is carried out making particle, particle is dried 1-5h within the scope of 30-45 DEG C, cross 20-40 mesh sieve;
(6) particle after sieving is added the dolomol mixing machine after pulverizing to mix, rotating speed is 10-15r/min, and the time is 6-8min, then carries out compressing tablet, obtains Radix Codonopsis bergamot dispersing tablet.
Embodiment 3
A kind of Radix Codonopsis bergamot dispersing tablet, comprises following parts by weight ingredient: Chinese yam 300 parts, Radix Angelicae Sinensis 300 parts, Radix Codonopsis 300 parts, bergamot 200 parts, microcrystalline cellulose 60 parts, Coriolus Versicolor P.E. 0.32 part, shitosan 0.32 part, vitamin C 2 parts, 0.2 part, calcium carbonate, 170 parts, sweet mellow wine, Sucralose 15 parts, superfine silica gel powder 50 parts, carboxymethyl cellulose 5 parts, sodium carboxymethyl starch 80 parts, dolomol 6 parts.
A preparation method for Radix Codonopsis bergamot dispersing tablet, comprises the following steps:
(1) get fresh Chinese yam to clean, peeling, stripping and slicing, put into boiling water blanching 3-5min, control water is placed in bruisher and is pounded thick slurry, will smash rear thick slurry temperature to pieces and control as within the scope of 60-65 DEG C, time is that 0.5-2h is dried, Chinese yam after drying is pulverized, crosses 80-100 mesh sieve, the Chinese yam after pulverizing is carried out high temperature instantaneous sterilization, temperature controls as within the scope of 115-120 DEG C, time is 5-10s, obtains yam flour, for subsequent use;
(2) get raw material Radix Angelicae Sinensis, Radix Codonopsis, bergamot clean, soak 1-3h, decoct extraction 3 times, each 1h, amount of water is raw material gross mass 8-10 times amount doubly, filters, merging filtrate, when filtrate is concentrated into 50 DEG C, relative density is the medicinal extract of 1.05-1.10, adding ethanol makes alcohol content be 60-75%, leaves standstill 12-24h, gets supernatant, reclaim ethanol and be concentrated into the thick paste of relative density 1.15-1.25, for subsequent use;
(3) get microcrystalline cellulose, Coriolus Versicolor P.E., shitosan, calcium carbonate, sweet mellow wine, Sucralose, superfine silica gel powder, carboxymethyl cellulose, sodium carboxymethyl starch, dolomol pulverize respectively, cross 100-150 mesh sieve, for subsequent use;
(4) thick paste that yam flour obtained for step (1), step (2) obtain is uniformly mixed, in mixture, add carboxymethyl cellulose, microcrystalline cellulose, Coriolus Versicolor P.E., shitosan, calcium carbonate, sweet mellow wine, Sucralose, superfine silica gel powder, sodium carboxymethyl starch after pulverizing in vitamin C and above-mentioned steps stir, mixer rotating speed is 10-20r/min, time is 10-20min, obtains mixture for subsequent use;
(5) mixture that step (4) is obtained is carried out making particle, particle is dried 1-5h within the scope of 30-45 DEG C, cross 20-40 mesh sieve;
(6) particle after sieving is added the dolomol mixing machine after pulverizing to mix, rotating speed is 10-15r/min, and the time is 6-8min, then carries out compressing tablet, obtains Radix Codonopsis bergamot dispersing tablet.
To those skilled in the art, obviously the invention is not restricted to the details of above-mentioned one exemplary embodiment, and when not deviating from spirit of the present invention or essential characteristic, the present invention can be realized in other specific forms.Therefore, no matter from which point, all should embodiment be regarded as exemplary, and be nonrestrictive, scope of the present invention is limited by claims instead of above-mentioned explanation, and all changes be therefore intended in the implication of the equivalency by dropping on claim and scope are included in the present invention.
In addition, be to be understood that, although this description is described according to embodiment, but not each embodiment only comprises an independently technical scheme, this narrating mode of description is only for clarity sake, those skilled in the art should by description integrally, and the technical scheme in each embodiment also through appropriately combined, can form other embodiments that it will be appreciated by those skilled in the art that.
Claims (3)
1. a Radix Codonopsis bergamot dispersing tablet, it is characterized in that, it is made up of the raw material of following weight portion: Chinese yam 250 parts, Radix Angelicae Sinensis 250 parts, Radix Codonopsis 250 parts, bergamot 150 parts, microcrystalline cellulose 50 parts, Coriolus Versicolor P.E. 0.22 part, shitosan 0.22 part, vitamin C 1.5 parts, 0.15 part, calcium carbonate, 135 parts, sweet mellow wine, Sucralose 12.5 parts, superfine silica gel powder 30 parts, carboxymethyl cellulose 4 parts, sodium carboxymethyl starch 67.5 parts, dolomol 5 parts;
Its preparation method comprises the following steps:
(1) get fresh Chinese yam to clean, peeling, stripping and slicing, put into boiling water blanching 3-5min, control water is placed in bruisher and is pounded thick slurry, will smash rear thick slurry temperature to pieces and control as within the scope of 60-65 DEG C, time is that 0.5-2h is dried, Chinese yam after drying is pulverized, crosses 80-100 mesh sieve, the Chinese yam after pulverizing is carried out high temperature instantaneous sterilization, temperature controls as within the scope of 115-120 DEG C, time is 5-10s, obtains yam flour, for subsequent use;
(2) get raw material Radix Angelicae Sinensis, Radix Codonopsis, bergamot clean, soak 1-3h, decoct extraction 3 times, each 1h, amount of water is raw material gross mass 8-10 times amount doubly, filters, merging filtrate, when filtrate is concentrated into 50 DEG C, relative density is the medicinal extract of 1.05-1.10, adding ethanol makes alcohol content be 60-75%, leaves standstill 12-24h, gets supernatant, reclaim ethanol and be concentrated into the thick paste of relative density 1.15-1.25, for subsequent use;
(3) get microcrystalline cellulose, Coriolus Versicolor P.E., shitosan, calcium carbonate, sweet mellow wine, Sucralose, superfine silica gel powder, carboxymethyl cellulose, sodium carboxymethyl starch, dolomol pulverize respectively, cross 100-150 mesh sieve, for subsequent use;
(4) thick paste that yam flour obtained for step (1), step (2) obtain is uniformly mixed, in mixture, add carboxymethyl cellulose, microcrystalline cellulose, Coriolus Versicolor P.E., shitosan, calcium carbonate, sweet mellow wine, Sucralose, superfine silica gel powder, sodium carboxymethyl starch after pulverizing in vitamin C and above-mentioned steps stir, mixer rotating speed is 10-20r/min, time is 10-20min, obtains mixture for subsequent use;
(5) mixture that step (4) is obtained is made particle, particle is dried 1-5h within the scope of 30-45 DEG C, cross 20-40 mesh sieve;
(6) particle after sieving is added the dolomol mixing machine after pulverizing to mix, rotating speed is 10-15r/min, and the time is 6-8min, then carries out compressing tablet, obtains Radix Codonopsis bergamot dispersing tablet.
2. a kind of Radix Codonopsis bergamot dispersing tablet according to claim 1, is characterized in that: get fresh Chinese yam in described step (1) and clean, peeling, stripping and slicing, puts into boiling water blanching 5min, and control water is placed in bruisher and is pounded thick slurry, rear thick slurry temperature will be smashed to pieces control to be under 60 DEG C of conditions, time is that 2h is dried, and is pulverized by the Chinese yam after drying, crosses 100 mesh sieves, Chinese yam after pulverizing is carried out high temperature instantaneous sterilization, it is within the scope of 115 DEG C that temperature controls, and the time is 10s, obtains yam flour.
3. a kind of Radix Codonopsis bergamot dispersing tablet according to claim 1, is characterized in that: get in described step (2) raw material Radix Angelicae Sinensis, Radix Codonopsis, bergamot clean, soak 1h, decoct extraction 3 times, each 1h, amount of water is raw material gross mass 8 times amount doubly, filters, merging filtrate, when filtrate is concentrated into 50 DEG C, relative density is the medicinal extract of 1.05, adds ethanol and makes alcohol content be 60%, leaves standstill 24h, get supernatant, reclaim ethanol and be concentrated into the thick paste of relative density 1.25.
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| WO2008119130A1 (en) * | 2007-04-02 | 2008-10-09 | Medcina Group Pty Ltd | Herbal compositions and methods for treating premenstrual syndrome |
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