CN103781482A - 用于调节细胞因子活性的方法 - Google Patents

用于调节细胞因子活性的方法 Download PDF

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Publication number
CN103781482A
CN103781482A CN201280030108.4A CN201280030108A CN103781482A CN 103781482 A CN103781482 A CN 103781482A CN 201280030108 A CN201280030108 A CN 201280030108A CN 103781482 A CN103781482 A CN 103781482A
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CN
China
Prior art keywords
hydroxyl
hydrogen
oxo
halogen
coverlet
Prior art date
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Pending
Application number
CN201280030108.4A
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English (en)
Chinese (zh)
Inventor
上野隆司
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Sucampo GmbH
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Sucampo GmbH
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Publication date
Application filed by Sucampo GmbH filed Critical Sucampo GmbH
Priority to CN201710153095.4A priority Critical patent/CN107028952A/zh
Publication of CN103781482A publication Critical patent/CN103781482A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/558—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Transplantation (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN201280030108.4A 2011-04-19 2012-04-18 用于调节细胞因子活性的方法 Pending CN103781482A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710153095.4A CN107028952A (zh) 2011-04-19 2012-04-18 用于调节细胞因子活性的方法

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201161476992P 2011-04-19 2011-04-19
US61/476,992 2011-04-19
US201161489516P 2011-05-24 2011-05-24
US61/489,516 2011-05-24
US201161537305P 2011-09-21 2011-09-21
US61/537,305 2011-09-21
US201161548458P 2011-10-18 2011-10-18
US61/548,458 2011-10-18
PCT/JP2012/061004 WO2012144649A1 (en) 2011-04-19 2012-04-18 Method for modulating cytokine activity

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201710153095.4A Division CN107028952A (zh) 2011-04-19 2012-04-18 用于调节细胞因子活性的方法

Publications (1)

Publication Number Publication Date
CN103781482A true CN103781482A (zh) 2014-05-07

Family

ID=47021806

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201280030108.4A Pending CN103781482A (zh) 2011-04-19 2012-04-18 用于调节细胞因子活性的方法
CN201710153095.4A Pending CN107028952A (zh) 2011-04-19 2012-04-18 用于调节细胞因子活性的方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201710153095.4A Pending CN107028952A (zh) 2011-04-19 2012-04-18 用于调节细胞因子活性的方法

Country Status (13)

Country Link
US (1) US20120270945A1 (https=)
EP (1) EP2699244A4 (https=)
JP (1) JP2014511825A (https=)
KR (1) KR20140043075A (https=)
CN (2) CN103781482A (https=)
AU (2) AU2012246999A1 (https=)
BR (1) BR112013026644A2 (https=)
CA (1) CA2831869A1 (https=)
IL (1) IL228700A0 (https=)
MX (1) MX2013012251A (https=)
RU (1) RU2013151166A (https=)
TW (1) TW201247615A (https=)
WO (1) WO2012144649A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2642744C (en) * 2006-02-28 2015-02-24 Sucampo Ag Method and composition for treating chronic obstructive pulmonary disease
WO2014159679A1 (en) 2013-03-12 2014-10-02 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Methods for using lubiprostone to absorb fluid from the subretinal space
US20150099802A1 (en) * 2013-10-03 2015-04-09 Sucampo Ag Selective tumor treatment
US20160228403A1 (en) * 2013-10-04 2016-08-11 Tohoku University Agent for preventing or ameliorating renal dysfunction
US20160120840A1 (en) * 2014-10-30 2016-05-05 Sucampo Ag Method and composition for treating nonerosive reflux disease

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0454429A2 (en) * 1990-04-27 1991-10-30 Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo Use of 15-dehydroxy-16-oxoprostaglandin derivatives in the treatment of allergic diseases
JPH0770054A (ja) * 1993-08-30 1995-03-14 R Tec Ueno:Kk 生化学的拮抗および疾患処置剤
JPH1029942A (ja) * 1996-04-02 1998-02-03 Yoichi Ichikawa 慢性関節リウマチ治療剤
CN101180096A (zh) * 2005-03-21 2008-05-14 苏坎波公司 用于治疗粘膜疾病的方法和组合物
CN101686985A (zh) * 2007-05-08 2010-03-31 国立大学法人浜松医科大学 含有ep4激动剂的细胞毒性t细胞的活化剂
EP2305304A1 (en) * 2008-04-28 2011-04-06 National University Corporation Hamamatsu University School of Medicine Immunopotentiating agent comprising ep1 agonist

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5166174A (en) * 1987-01-28 1992-11-24 K.K. Ueno Seiyaku Oyo Kenkyujo Prostaglandins E and anti-ulcers containing same
CA2150287C (en) * 1994-06-03 2004-08-10 Ryuji Ueno Agent for treating hepato-biliary diseases
US8202909B2 (en) * 2005-01-27 2012-06-19 Sucampo Ag Method for treating central nervous system disorders
KR20160120809A (ko) * 2005-03-04 2016-10-18 수캄포 아게 말초 혈관 질환 치료를 위한 방법 및 조성물
US20060281818A1 (en) * 2005-03-21 2006-12-14 Sucampo Ag, North Carolina State University Method for treating mucosal disorders
RU2468800C2 (ru) * 2005-04-12 2012-12-10 Сукампо Аг Комбинированное применение производного простагландина и ингибитора протонового насоса для лечения желудочно-кишечных заболеваний
CA2642744C (en) * 2006-02-28 2015-02-24 Sucampo Ag Method and composition for treating chronic obstructive pulmonary disease
JP2011032262A (ja) * 2009-06-30 2011-02-17 Sucampo Ag Ｎｓａｉｄの長期使用のための医薬組成物
BR112013009163A2 (pt) * 2010-10-15 2016-07-26 Scinopharm Kunshan Biochemical Technology Co Ltd processo para preparação de lubiprostona

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0454429A2 (en) * 1990-04-27 1991-10-30 Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo Use of 15-dehydroxy-16-oxoprostaglandin derivatives in the treatment of allergic diseases
JPH0770054A (ja) * 1993-08-30 1995-03-14 R Tec Ueno:Kk 生化学的拮抗および疾患処置剤
JPH1029942A (ja) * 1996-04-02 1998-02-03 Yoichi Ichikawa 慢性関節リウマチ治療剤
CN101180096A (zh) * 2005-03-21 2008-05-14 苏坎波公司 用于治疗粘膜疾病的方法和组合物
CN101686985A (zh) * 2007-05-08 2010-03-31 国立大学法人浜松医科大学 含有ep4激动剂的细胞毒性t细胞的活化剂
EP2305304A1 (en) * 2008-04-28 2011-04-06 National University Corporation Hamamatsu University School of Medicine Immunopotentiating agent comprising ep1 agonist

Also Published As

Publication number Publication date
EP2699244A1 (en) 2014-02-26
JP2014511825A (ja) 2014-05-19
CA2831869A1 (en) 2012-10-26
IL228700A0 (en) 2013-12-31
AU2017203276A1 (en) 2017-06-08
MX2013012251A (es) 2014-01-20
CN107028952A (zh) 2017-08-11
BR112013026644A2 (pt) 2016-12-27
KR20140043075A (ko) 2014-04-08
US20120270945A1 (en) 2012-10-25
TW201247615A (en) 2012-12-01
NZ616027A (en) 2015-09-25
RU2013151166A (ru) 2015-05-27
EP2699244A4 (en) 2014-10-22
AU2012246999A1 (en) 2013-10-17
WO2012144649A1 (en) 2012-10-26

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Application publication date: 20140507

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