CN103781271A - Atmospheric pressure cold plasma generating device for wound healing - Google Patents
Atmospheric pressure cold plasma generating device for wound healing Download PDFInfo
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- CN103781271A CN103781271A CN201410022350.8A CN201410022350A CN103781271A CN 103781271 A CN103781271 A CN 103781271A CN 201410022350 A CN201410022350 A CN 201410022350A CN 103781271 A CN103781271 A CN 103781271A
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Abstract
The invention discloses a plasma generating device for wound healing. The plasma generating device comprises a grounded stainless steel cap. The inner wall of the cap is provided with a layer of insulating medium, the top of the cap is opened, and the bottom portion of the cap is provided with a cylindrical insulating base. A high-voltage electrode sleeved in a quartz medium tube is arranged in the stainless steel cap through the center of the insulating base. The front end of the high-voltage electrode is a discharge end, and the rear end of the high-voltage electrode is connected with a high-voltage power source. The rear end of the high-voltage electrode is connected with an insulating base installation adjustable device, and connected with an insulating base installation insulating medium housing. One side of the stainless steel cap is provided with a working gas intake passage. Two ends of the quartz medium tube are opened. The adjustable device is used to adjust the discharge space between the high-voltage electrode and the cap ground electrode. The device of the invention is easy to fabricate, has advantages of simple, convenient and safe utilization and wide discharge gas range, can be used to solve the air and nitrogen discharge problem, has advantages of low plasma temperature, high particle density and various active ingredients, and can be used in the wound healing, so the atmospheric pressure plasma application range can be further expanded.
Description
Technical field
The invention belongs to normal pressure cold plasma generating means, be specifically related to a kind of atmos low-temperature plasma generating means that can be used for wound healing.
Background technology
Normal-pressure non-equilibrium plasma is because it does not need vacuum system, and its plasma space enrichment ion, electronics, excited atom, molecule and free radical etc. are all active reactive species, these active particle quantity are large, kind is many, activity is strong, are easy to react with contacted material surface.Therefore normal-pressure non-equilibrium plasma is in the very large application prospect that has of the aspects such as the surface treatment of space flight, environment, biologic medical, material, food sterilization, waste water treatment.
In prior art, atmospheric plasma, by the relation of plasma temperature and electron temperature, mainly contains normal pressure equilibrium plasma and normal-pressure non-equilibrium plasma.These two kinds of atmospheric plasmas, due to the difference of plasma characteristics, have different application.Normal pressure equilibrium plasma often refers to the hot plasma of plasma temperature more than several thousand Kelvins, the fields such as this class plasma has that high temperature, highdensity characteristic are often used to that plasma material is synthetic, plasma spray coating and metal melting welding.And normal-pressure non-equilibrium plasma is because plasma temperature is much smaller than electron temperature, make plasma in keeping abundant active particle composition, plasma temperature only has hundreds of Kelvin.This nonequilibrium behavior is usually used in processing and the biomedical application of non-high-temperature resistant surfacing.
Conventional normal-pressure non-equilibrium plasma adopts dielectric barrier discharge form and working gas mostly to be inert working gas as argon gas and helium generation more.And these working gas price general charged costlinesses, so adopt comparatively cheap nitrogen, oxygen, air also just to become and have more practical significance as working gas.
Summary of the invention
The invention provides a kind of normal-pressure non-equilibrium cold plasma generating means that can be used for wound healing, can adopt inert gas as helium, argon gas and oxygen-doped gas thereof, can be also that lower-cost nitrogen (nitrogen is oxygen-doped), oxygen and air etc. are as working gas.
For achieving the above object, the present invention takes following technical scheme:
A kind of normal pressure cold plasma generating means that can be used for wound healing, comprise the stainless steel cylinder cap of ground connection, this cap inwall is close to the dielectric of one deck polytetrafluoro material, open top, bottom is provided with cylindrical insulator foot, cover has the high-field electrode of quartz medium pipe to be placed in stainless steel cylinder cap by cylindrical insulator foot center, high-field electrode front end is as discharge end, be in stainless steel cylinder cap top area, rear end is connected with high voltage source, connecting insulator foot in high-field electrode rear end tunable arrangement is being installed, described tunable arrangement is equipped with forming of scale with scale by insulative cylinders piece and side, and connecting insulator foot and installing the dielectric shell of polytetrafluoro material, described stainless steel cylinder cap one side has working gas inlet channel, described quartz medium pipe open at both ends, makes to stop without dielectric layer between described high-field electrode discharge end and the open top of stainless steel cylinder cap, regulates the discharging distance between high-field electrode and cylinder cap ground electrode by described tunable arrangement.
The shape of the discharge end of described high-field electrode can be plane structure or cone-shaped structure.
Described high-field electrode material can be the conductive corrosion-resistant material such as copper, tungsten.
Described high voltage source can be AC power or DC power supply, and its inside has current-limiting function, to guarantee the low-temperature characteristics of atmospheric plasma generating means.
Described high-voltage ac power output voltage is adjustable from 0-25KV, and output frequency is adjustable from 10kHz to 50kHz.
Under fixing described high voltage source output voltage, frequency and fixed air flow condition, by regulating discharging distance, can change length and temperature occur.
Under fixing discharging distance and fixed air flow condition, by regulating described high voltage source output voltage and frequency, can change length and temperature occur.
Under fixing described high voltage source output voltage, frequency and fixing discharging distance condition, by changing gas flow, can change length and temperature occur.
Described high-field electrode discharge end acts on working gas can produce the nitrogen oxide that can promote fast in a large number wound healing, active oxygen isoreactivity particle composition.
The present invention has following remarkable advantage:
(1), owing to producing plasma under condition of normal pressure, without expensive vacuum equipment, convenience simple in structure, be easy to make, cost is low.
(2), because high-field electrode is as in stainless steel cylinder, have dielectric and ground protection outward, safe and reliable, can contact.
(3), between electrode without dielectric barrier, power supply has current-limiting function, plasma active particle density is high, has low-temperature characteristics simultaneously.
(4), by regulate discharging distance regulate plasma discharge intensity, can change plasma temperature and active particle density, can be used for different applications as plasma medical science and surface clean etc., expanded range of application
(5), can adopt nitrogen (nitrogen is oxygen-doped), oxygen, air can greatly reduce costs as working gas.
Accompanying drawing explanation
Fig. 1 is the present invention's (plane-shaped electrode) structural representation.
Fig. 2 is the present invention's (coniform electrode) structural representation.
Embodiment
As Fig. 1, shown in 2, a kind of normal pressure cold plasma generating means that can be used for wound healing, comprise the stainless steel cylinder cap 5 of ground connection, this cap inwall is close to the dielectric of one deck polytetrafluoro material, open top, bottom is provided with cylindrical insulator foot 9, cover has the high-field electrode 4 of quartz medium pipe 3 to be placed in stainless steel cylinder cap 5 through cylindrical insulator foot center, high-field electrode front end is as discharge end, be in stainless steel cylinder cap top area 6, rear end is connected with high voltage source 1, connecting insulator foot in high-field electrode rear end tunable arrangement is being installed, described tunable arrangement is equipped with forming of scale 10 with scale by insulative cylinders piece and side, and connecting insulator foot and installing the dielectric shell 11 of polytetrafluoro material, described stainless steel cylinder cap one side has working gas inlet channel 2, inlet channel connects gas cylinder by flowmeter, described quartz medium pipe open at both ends, make to stop without dielectric layer between described high-field electrode discharge end and the open top of stainless steel cylinder cap, form plasma reaction district 7, high-field electrode 4 discharge ends are plane or coniform, regulate the discharging distance between high-field electrode and cylinder cap ground electrode by described tunable arrangement, and then the strength of discharge in change plasma reaction district 7, and under the guiding function of air-flow, blow out stainless steel cylinder formation plasma 8.
High-field electrode 4 materials can be the conductive corrosion-resistant materials such as copper, tungsten, high voltage source 1 can be DC power supply or AC power, by the working gas of inlet channel 2 can be both inert gas as helium, argon gas and oxygen-doped gas thereof, can be also the gases such as more cheap nitrogen (nitrogen is oxygen-doped), oxygen and air.
Change power supply 1 output voltage, frequency, discharging distance and the throughput that enters inlet channel 2 can change length and the plasma temperature of plasma 8.Take nitrogen electric discharge as example, fixing output voltage is 6 kV, frequency 32 kHz, and throughput 20 L/min, by regulating discharging distance (2-6 mm), can realize plasma 8 length from 2-3 cm, and temperature is from the variation of 300-330K.
Take nitrogen electric discharge as example, fixing discharging distance 4 mm, output frequency 32 kHz, throughput 20 L/min, can realize plasma 8 length 2.5-3.5 cm, the variation of temperature 300-400K by changing output voltage (6KV-9KV).
Take nitrogen electric discharge as example, fixing discharging distance 4 mm, output voltage 6 kV, frequency 32 kHz, change throughput (5-40 L/min) and can realize plasma 8 length 2-6 cm, the variation of temperature 300-450K.
Take nitrogen electric discharge as example, be 6 kV at output voltage, frequency 32 kHz, throughput 20 L/min, under discharging distance 4 mm rigid conditions, under the condition of occurrence temperature 300K left and right, can be in 5 min will be coated on Pseudomonas aeruginosa on agar plate from 10
6cFU kills completely.
Claims (5)
1. one kind can be used for the normal pressure cold plasma generating means of wound healing, comprise the stainless steel cylinder cap of ground connection, this cap inwall is close to the dielectric of one deck polytetrafluoro material, open top, bottom is provided with cylindrical insulator foot, cover has the high-field electrode of quartz medium pipe to be placed in stainless steel cylinder cap by cylindrical insulator foot center, high-field electrode front end is as discharge end, be in stainless steel cylinder cap top area, rear end is connected with high voltage source, connecting insulator foot in high-field electrode rear end tunable arrangement is being installed, described tunable arrangement is equipped with forming of scale with scale by insulative cylinders piece and side, and connecting insulator foot and installing the dielectric shell of polytetrafluoro material, it is characterized in that: described stainless steel cylinder cap one side has working gas inlet channel, described quartz medium pipe open at both ends, makes to stop without dielectric layer between described high-field electrode discharge end and the open top of stainless steel cylinder cap, regulates the discharging distance between high-field electrode and cylinder cap ground electrode by described tunable arrangement.
2. according to the normal pressure cold plasma generating means that can be used for wound healing claimed in claim 1, it is characterized in that: the shape of the discharge end of described high-field electrode can be plane structure or cone-shaped structure.
3. according to the normal pressure cold plasma generating means that can be used for wound healing claimed in claim 1, it is characterized in that: described high-field electrode material can be the conductive corrosion-resistant material such as copper, tungsten.
4. according to the normal pressure cold plasma generating means that can be used for wound healing claimed in claim 1, it is characterized in that: described high voltage source can be AC power or DC power supply.
5. according to the normal pressure cold plasma generating means that can be used for wound healing claimed in claim 1, it is characterized in that: described high-field electrode discharge end acts on working gas and produces the active particle composition that can promote fast in a large number wound healing.
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| CN201410022350.8A CN103781271A (en) | 2014-01-16 | 2014-01-16 | Atmospheric pressure cold plasma generating device for wound healing |
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| CN201410022350.8A CN103781271A (en) | 2014-01-16 | 2014-01-16 | Atmospheric pressure cold plasma generating device for wound healing |
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Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104661423A (en) * | 2015-02-09 | 2015-05-27 | 清华大学 | Large-atmosphere low-temperature plasma fluidic generator |
| CN106488641A (en) * | 2016-12-27 | 2017-03-08 | 中金瑞峰资本管理有限公司 | A kind of portable plasma device that can be used for wound disinfection |
| CN107182165A (en) * | 2017-06-20 | 2017-09-19 | 华中科技大学 | A kind of plasma emission device based on hot cathode |
| CN107519573A (en) * | 2017-09-30 | 2017-12-29 | 武汉资联虹康科技股份有限公司 | A kind of ear-clip electrodes with indicator lamp |
| CN107582375A (en) * | 2017-09-30 | 2018-01-16 | 武汉资联虹康科技股份有限公司 | A kind of ear-clip electrodes with fiber optic conduction |
| CN108566716A (en) * | 2018-06-09 | 2018-09-21 | 贵州电网有限责任公司 | A kind of gas discharge plasma jet apparatus |
| CN109475037A (en) * | 2018-12-14 | 2019-03-15 | 华中科技大学 | A kind of plasma active enhancing method and generating device |
| CN110336142A (en) * | 2019-08-02 | 2019-10-15 | 西安交通大学 | A kind of safety grounding device of plasma jet |
| CN111617716A (en) * | 2020-06-09 | 2020-09-04 | 常州大学 | Metal honeycomb type plasma discharge reactor |
| JP2021003631A (en) * | 2015-08-31 | 2021-01-14 | 積水化学工業株式会社 | Method and device for cleaning inside of oral cavity |
| CN115023018A (en) * | 2022-03-18 | 2022-09-06 | 大连理工大学 | Discharge electrode for simulating boundary local mode |
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Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104661423A (en) * | 2015-02-09 | 2015-05-27 | 清华大学 | Large-atmosphere low-temperature plasma fluidic generator |
| JP2021003631A (en) * | 2015-08-31 | 2021-01-14 | 積水化学工業株式会社 | Method and device for cleaning inside of oral cavity |
| CN106488641A (en) * | 2016-12-27 | 2017-03-08 | 中金瑞峰资本管理有限公司 | A kind of portable plasma device that can be used for wound disinfection |
| CN107182165A (en) * | 2017-06-20 | 2017-09-19 | 华中科技大学 | A kind of plasma emission device based on hot cathode |
| CN107182165B (en) * | 2017-06-20 | 2024-05-14 | 华中科技大学 | Plasma emission device based on thermionic emission cathode |
| CN107519573A (en) * | 2017-09-30 | 2017-12-29 | 武汉资联虹康科技股份有限公司 | A kind of ear-clip electrodes with indicator lamp |
| CN107582375A (en) * | 2017-09-30 | 2018-01-16 | 武汉资联虹康科技股份有限公司 | A kind of ear-clip electrodes with fiber optic conduction |
| CN108566716A (en) * | 2018-06-09 | 2018-09-21 | 贵州电网有限责任公司 | A kind of gas discharge plasma jet apparatus |
| CN108566716B (en) * | 2018-06-09 | 2024-01-12 | 贵州电网有限责任公司 | Gas discharge plasma jet device |
| CN109475037A (en) * | 2018-12-14 | 2019-03-15 | 华中科技大学 | A kind of plasma active enhancing method and generating device |
| CN110336142B (en) * | 2019-08-02 | 2020-04-17 | 西安交通大学 | Plasma jet safe grounding device |
| CN110336142A (en) * | 2019-08-02 | 2019-10-15 | 西安交通大学 | A kind of safety grounding device of plasma jet |
| CN111617716A (en) * | 2020-06-09 | 2020-09-04 | 常州大学 | Metal honeycomb type plasma discharge reactor |
| CN115023018A (en) * | 2022-03-18 | 2022-09-06 | 大连理工大学 | Discharge electrode for simulating boundary local mode |
| CN115023018B (en) * | 2022-03-18 | 2024-04-16 | 大连理工大学 | Discharge electrode system for simulating boundary local mode |
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Application publication date: 20140507 |
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