CN103768650A - Wound regenerating and repairing bandage and manufacture method thereof - Google Patents
Wound regenerating and repairing bandage and manufacture method thereof Download PDFInfo
- Publication number
- CN103768650A CN103768650A CN201410038110.7A CN201410038110A CN103768650A CN 103768650 A CN103768650 A CN 103768650A CN 201410038110 A CN201410038110 A CN 201410038110A CN 103768650 A CN103768650 A CN 103768650A
- Authority
- CN
- China
- Prior art keywords
- wound
- acid salt
- alginic acid
- film
- salt deposit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Landscapes
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention relates to the technical field of medical application, and in particular relates to wound regenerating and repairing bandage and a manufacture method thereof. The wound regenerating and repairing bandage comprises a surface protective layer, wherein a therapy pad is arranged at one side of the surface protective layer, and comprises a nano-fiber membrane, an anti-bacterial chitosan membrane and an alginate layer which are arranged in sequence; the alginate layer is connected with the surface protective layer. The wound regenerating and repairing bandage manufactured by using the method has a remarkable effect in stopping bleeding, resisting bacteria, accelerating wound heating and relieving pains for a wound, is excellent in adhesion, breathability and comfort, can prevent wound adhesion, and has high functions of water absorption and moistening.
Description
Technical field
The present invention relates to medical dressing technical field, in particular to a kind of wound Regeneration and Repair binder and preparation method thereof.
Background technology
The effect of binder is flap coverage, and the dressing on it is to help wound healing, and wherein, the dressing generally using in medical treatment at present, has the following disadvantages:
1, the imbibition antiseep weak effect of dressing; 2, easy and wound sticks together, and easily causes secondary damage while withdrawing dressing; 3, dressing self does not have antibacterial, to promote healing and pain relieving function, causes a large amount of antibiotic uses; 4, dressing does not have the function that reduces cicatrix.
Summary of the invention
The object of the present invention is to provide a kind of wound Regeneration and Repair binder and preparation method thereof, to solve the above problems.
A kind of wound Regeneration and Repair binder is provided in an embodiment of the present invention, has comprised sealer, a side of described sealer is provided with treatment pad; Described treatment pad comprises the nano fibrous membrane being arranged in order, antibacterial chitosan film and alginic acid salt deposit, and described alginic acid salt deposit is connected with described sealer.
Preferably, the thickness of described treatment pad is 0.03mm-10mm.
Preferably, the fibre diameter of described nano fibrous membrane is 10-1000nm.
A manufacture method for wound Regeneration and Repair binder, comprises the following steps:
Prepare nano fibrous membrane by thering are one or both in bioactive collagen film and hyaluronic acid membrane;
Prepare antibacterial chitosan film by the chitosan of deacetylation >=80%;
Prepare alginic acid salt deposit by alginate;
Nano fibrous membrane, antibacterial chitosan film and alginic acid salt deposit are superposeed in order and form treatment pad;
Prepare sealer by self-adhering-type polyurethane water-proof breathable films;
Sargassum hydrochloric acid layer on treatment pad is connected with sealer stack, makes wound Regeneration and Repair binder.
Further, preparing nano fibrous membrane is: choose and have one or both in bioactive collagen film and hyaluronic acid membrane and prepare electrostatic spinning raw material solution, after vacuum deaerator, under highfield exists, by macromolecular solution is imported to electrostatic charge, thereby make described electrostatic spinning raw material solution jet in electric field prepare nano fibrous membrane.
Further, preparing antibacterial chitosan film is: the chitosan of choosing deacetylation >=80% is prepared chitosan electrostatic spinning raw material solution, after vacuum deaerator, under highfield exists, by macromolecular solution is imported to electrostatic charge, prepare antibacterial chitosan film thereby make it jet in electric field.
Further, preparing antibacterial chitosan film is: choose the chitin fiber of deacetylation>=80% through acupuncture or water thorn, the grammes per square metre obtaining is 100-220g/m
2chitin fiber non-weaving cloth form antibacterial chitosan film.
Further, preparing alginic acid salt deposit is: choose sodium alginate and be made into electrostatic spinning raw material solution, after vacuum deaerator, in electrospinning device, carry out electrostatic spinning, obtain sodium alginate film, sodium alginate film is immersed in to 2% calcium chloride solution 2-12 hour, and then with pure water washing, the dry alginic acid salt deposit that obtains.
Further, preparing alginic acid salt deposit is: choosing length is the alginate fiber that 20-80mm and fiber number are 0.6-4dtex, and the acupuncture in nonwovens process or water sting, and the grammes per square metre obtaining is 80-240g/m
2alginate fiber non-weaving cloth form alginic acid salt deposit.
, there is following advantage in a kind of wound Regeneration and Repair binder that the embodiment of the present invention provides and preparation method thereof:
1. can particularly blood be compatible mutually with active mass, non-immunogenicity and immunoreactivity;
Thereby 2. regulate wound surface oxygen tension, promote blood capillary to form accelerating wound healing;
3. environment moist, micro-acid is conducive to neutrophilic granulocyte and plays a role, and strengthens local bactericidal ability, reduces infection rate;
4. there is good permeability for moisture and electrolyte, and can be close to but adhesion with irregular wound surface, reduce the chance of bacteria breed;
5. mechanical strength and plasticity are strong, need to be prepared into various shapes and size according to wound surface;
6. outward appearance softness, feels comfortable, and range of application is very extensive, can be used for extensive wound, burn; Chronic wound and cases with refractory pressure sore; Face and body surface cosmetic surgery; The complex structures such as hands, foot and joint are difficult to wrap up fixing position etc.
Accompanying drawing explanation
Fig. 1 shows the explosive view of a kind of wound Regeneration and Repair binder described in the embodiment of the present invention.
In figure:
1, sealer; 2, nano fibrous membrane; 3, antibacterial chitosan film; 4, alginic acid salt deposit.
The specific embodiment
Also by reference to the accompanying drawings the present invention is described in further detail below by specific embodiment.
As shown in Figure 1, a kind of wound Regeneration and Repair binder, comprises sealer 1, and a side of sealer 1 is provided with treatment pad; Treatment pad comprises the nano fibrous membrane 2, antibacterial chitosan film 3 and the alginic acid salt deposit 4 that are arranged in order, and alginic acid salt deposit 4 is connected with sealer 1.
Preferably, the thickness for the treatment of pad is 0.03mm-10mm.
Preferably, the fibre diameter of nano fibrous membrane 2 is 10-1000nm.
A manufacture method for wound Regeneration and Repair binder, comprises the following steps:
Prepare nano fibrous membrane 2 by thering are one or both in bioactive collagen film and hyaluronic acid membrane;
Prepare antibacterial chitosan film 3 by the chitosan of deacetylation >=80%;
Prepare alginic acid salt deposit 4 by alginate;
Nano fibrous membrane 2, antibacterial chitosan film 3 and alginic acid salt deposit 4 are superposeed in order and form treatment pad;
Prepare sealer 1 by self-adhering-type polyurethane water-proof breathable films;
Sargassum hydrochloric acid layer on treatment pad is superposeed and is connected with sealer 1, make wound Regeneration and Repair binder.
Preparing nano fibrous membrane 2 is: choose and have one or both in bioactive collagen film and hyaluronic acid membrane and prepare electrostatic spinning raw material solution, after vacuum deaerator, under highfield exists, by macromolecular solution is imported to electrostatic charge, thereby make electrostatic spinning raw material solution jet in electric field prepare nano fibrous membrane 2.
The tridimensional network that utilizes nano fibrous membrane 2 prepared by method of electrostatic spinning to there is high specific surface area, high porosity and be interconnected, therefore can provide extracellular matrix similar microenvironment for Skin Cell growth, Promote cell's growth and growth, and then promotion wound healing, compared with traditional dressing, speed of wound healing is on average accelerated 3-5 days, and can significantly reduce the formation of cicatrix, cicatrix size reduction 30-60%.
Preparing antibacterial chitosan film 3 is two kinds of modes, that the chitosan of choosing deacetylation >=80% is prepared a chitosan electrostatic spinning raw material solution, after vacuum deaerator, under highfield exists, by macromolecular solution is imported to electrostatic charge, prepare antibacterial chitosan film 3 thereby make it jet in electric field.
Another kind is to choose the chitin fiber of deacetylation>=80% through acupuncture or water thorn, and the grammes per square metre obtaining is 100-220g/m
2chitin fiber non-weaving cloth form antibacterial chitosan film 3.
The chitosan of deacetylation >=80% has significant antibiotic property, can effectively stop the infection of antibacterial to wound, thus accelerating wound, and reduce antibiotic use.
Preparing alginic acid salt deposit 4 is two kinds of modes, one is to choose sodium alginate to be made into electrostatic spinning raw material solution, after vacuum deaerator, in electrospinning device, carry out electrostatic spinning, obtain sodium alginate film, sodium alginate film is immersed in to 2% calcium chloride solution 2-12 hour, and then with pure water washing, the dry alginic acid salt deposit 4 that obtains.
Another kind is that to choose length be the alginate fiber that 20-80mm and fiber number are 0.6-4dtex, the acupuncture in nonwovens process or water thorn, and the grammes per square metre obtaining is 80-240g/m
2alginate fiber non-weaving cloth form alginic acid salt deposit 4.
Alginic acid salt deposit 4, for wound provides calcium ion, promotes blood coagulation pain relieving, imbibition moisturizing, promotes wound healing.
, there is following advantage in a kind of wound Regeneration and Repair binder that the embodiment of the present invention provides and preparation method thereof:
1. can particularly blood be compatible mutually with active mass, non-immunogenicity and immunoreactivity;
Thereby 2. regulate wound surface oxygen tension, promote blood capillary to form accelerating wound healing;
3. environment moist, micro-acid is conducive to neutrophilic granulocyte and plays a role, and strengthens local bactericidal ability, reduces infection rate;
4. there is good permeability for moisture and electrolyte, and can be close to but adhesion with irregular wound surface, reduce the chance of bacteria breed;
5. mechanical strength and plasticity are strong, need to be prepared into various shapes and size according to wound surface;
6. outward appearance softness, feels comfortable, and range of application is very extensive, can be used for extensive wound, burn; Chronic wound and cases with refractory pressure sore; Face and body surface cosmetic surgery; The complex structures such as hands, foot and joint are difficult to wrap up fixing position etc.
This wound Regeneration and Repair binder does not limit the thickness of each layer of structure, can according to different wound kinds from choose different thickness period; Every layer can be added antibiotic etc composition.In addition, do not limit the concrete shape of binder yet, can make as required circle, square, rectangle, ellipse, polygon etc.
In a word, compared with traditional dressing, wound Regeneration and Repair binder provided by the invention, to wound such as hemostasis, antibacterial, promote that wound healing and pain relieving have significant effect.Stickiness, breathability, comfortableness are better, can prevent from adhesion that wound is caused having higher water absorption and moisture-keeping functions.Can be widely used in wound hemostasis, promote wound and ulcer healing, reduce cicatrix, remove the aspects such as speckle in burn and scald, medical science face-lifting and beauty treatment and also there is remarkable result.
The foregoing is only the preferred embodiments of the present invention, be not limited to the present invention, for a person skilled in the art, the present invention can have various modifications and variations.Within the spirit and principles in the present invention all, any modification of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.
Claims (9)
1. a wound Regeneration and Repair binder, is characterized in that, comprises sealer, and a side of described sealer is provided with treatment pad; Described treatment pad comprises the nano fibrous membrane being arranged in order, antibacterial chitosan film and alginic acid salt deposit, and described alginic acid salt deposit is connected with described sealer.
2. wound Regeneration and Repair binder according to claim 1, is characterized in that, the thickness of described treatment pad is 0.03mm-10mm.
3. wound Regeneration and Repair binder according to claim 1, is characterized in that, the fibre diameter of described nano fibrous membrane is 10-1000nm.
4. a manufacture method for wound Regeneration and Repair binder, is characterized in that, comprises the following steps:
Prepare nano fibrous membrane by thering are one or both in bioactive collagen film and hyaluronic acid membrane;
Prepare antibacterial chitosan film by the chitosan of deacetylation >=80%;
Prepare alginic acid salt deposit by alginate;
Nano fibrous membrane, antibacterial chitosan film and alginic acid salt deposit are superposeed in order and form treatment pad;
Prepare sealer by self-adhering-type polyurethane water-proof breathable films;
Sargassum hydrochloric acid layer on treatment pad is connected with sealer stack, makes wound Regeneration and Repair binder.
5. the manufacture method of wound Regeneration and Repair binder according to claim 4, it is characterized in that, preparing nano fibrous membrane is: choose and have one or both in bioactive collagen film and hyaluronic acid membrane and prepare electrostatic spinning raw material solution, after vacuum deaerator, under highfield exists, by macromolecular solution is imported to electrostatic charge, thereby make described electrostatic spinning raw material solution jet in electric field prepare nano fibrous membrane.
6. the manufacture method of wound Regeneration and Repair binder according to claim 4, it is characterized in that, preparing antibacterial chitosan film is: the chitosan of choosing deacetylation >=80% is prepared chitosan electrostatic spinning raw material solution, after vacuum deaerator, under highfield exists, by macromolecular solution is imported to electrostatic charge, prepare antibacterial chitosan film thereby make it jet in electric field.
7. the manufacture method of wound Regeneration and Repair binder according to claim 4, is characterized in that, prepares antibacterial chitosan film to be: choose the chitin fiber of deacetylation>=80% through acupuncture or water thorn, the grammes per square metre obtaining is 100-220g/m
2chitin fiber non-weaving cloth form antibacterial chitosan film.
8. the manufacture method of wound Regeneration and Repair binder according to claim 4, it is characterized in that, preparing alginic acid salt deposit is: choose sodium alginate and be made into electrostatic spinning raw material solution, after vacuum deaerator, in electrospinning device, carry out electrostatic spinning, obtain sodium alginate film, sodium alginate film is immersed in to 2% calcium chloride solution 2-12 hour, and then with pure water washing, the dry alginic acid salt deposit that obtains.
9. the manufacture method of wound Regeneration and Repair binder according to claim 4, it is characterized in that, preparing alginic acid salt deposit is: choosing length is the alginate fiber that 20-80mm and fiber number are 0.6-4dtex, the acupuncture in nonwovens process or water thorn, and the grammes per square metre obtaining is 80-240g/m
2alginate fiber non-weaving cloth form alginic acid salt deposit.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410038110.7A CN103768650A (en) | 2014-01-26 | 2014-01-26 | Wound regenerating and repairing bandage and manufacture method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410038110.7A CN103768650A (en) | 2014-01-26 | 2014-01-26 | Wound regenerating and repairing bandage and manufacture method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103768650A true CN103768650A (en) | 2014-05-07 |
Family
ID=50561704
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410038110.7A Pending CN103768650A (en) | 2014-01-26 | 2014-01-26 | Wound regenerating and repairing bandage and manufacture method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103768650A (en) |
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104224446A (en) * | 2014-09-03 | 2014-12-24 | 常州好安生物科技有限公司 | Alginate adhesive bandage and manufacturing method of alginate adhesive bandage |
| CN104490519A (en) * | 2014-12-19 | 2015-04-08 | 苏州全润医疗科技有限公司 | Multifunctional medical bandage |
| CN105463700A (en) * | 2015-12-18 | 2016-04-06 | 厦门百美特生物材料科技有限公司 | Spunlace alginate dressing |
| CN106983902A (en) * | 2017-04-18 | 2017-07-28 | 青岛科技大学 | A kind of novel nano composite wound bandage |
| CN107158447A (en) * | 2017-07-06 | 2017-09-15 | 华南理工大学 | A kind of antibacterial zeins dressing with controllable orientation and preparation method thereof |
| CN107397974A (en) * | 2017-09-11 | 2017-11-28 | 北京煜煌科技有限公司 | A kind of wound patch for treating chronic trauma |
| CN107485484A (en) * | 2017-09-01 | 2017-12-19 | 山东汉方生物科技有限公司 | Suitable for general sexual trauma, the wound of chronic trauma patch |
| CN107789661A (en) * | 2017-09-26 | 2018-03-13 | 华南理工大学 | A kind of hemostatic and antibacterial nanometer film and preparation method thereof |
| CN108852454A (en) * | 2018-09-07 | 2018-11-23 | 北京健康广济生物技术有限公司 | A kind of hemostasis device for arterial blood gas acquisition |
| CN110841102A (en) * | 2019-11-29 | 2020-02-28 | 青岛农业大学 | Composite nanofiber elastic bandage and preparation method thereof |
| CN111249515A (en) * | 2020-03-11 | 2020-06-09 | 西安工程大学 | Biomedical dressing with antibacterial, anti-inflammatory and wound healing promoting functions and preparation method thereof |
| CN111481731A (en) * | 2019-01-29 | 2020-08-04 | 中国人民解放军海军特色医学中心 | Collagen-chitosan electrostatic spinning membrane composite alginate anti-seawater soaking application and preparation method thereof |
| CN111557790A (en) * | 2020-05-16 | 2020-08-21 | 江苏德鲁克生物科技有限公司 | Antibacterial and disinfectant nanofiber medical dressing |
Citations (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1634607A (en) * | 2003-12-30 | 2005-07-06 | 上海中大科技发展有限公司 | Medical biomaterial and method for manufacturing the same |
| CN1686572A (en) * | 2005-05-13 | 2005-10-26 | 褚省吾 | Ultra strong absorption calcium alginate henatischesis dressing and its preparation method |
| US20090018479A1 (en) * | 2002-06-14 | 2009-01-15 | Hemcon Medical Technologies, Inc. | Absorbable tissue dressing assemblies, systems, and methods formed from hydrophilic polymer sponge structures such as chistosan |
| CN201333128Y (en) * | 2008-12-23 | 2009-10-28 | 上海海洋大学 | Heath care adhesive bandage |
| KR20100021108A (en) * | 2008-08-14 | 2010-02-24 | 주식회사 아모메디 | Antibacterial wound dressing laminate and method of preparing the same |
| CN102600019A (en) * | 2012-03-09 | 2012-07-25 | 烟台万利医用品有限公司 | Medical hydrogel dressing and preparation method thereof |
| CN102600018A (en) * | 2012-03-31 | 2012-07-25 | 华南理工大学 | Medical dressing with cooling function and wound healing prompting function and preparation method of medical dressing |
| CN103169570A (en) * | 2013-03-06 | 2013-06-26 | 苏州艾美医疗用品有限公司 | Hemostasis bandaid and preparation method thereof |
| CN203089549U (en) * | 2013-02-28 | 2013-07-31 | 武汉百美特生物材料科技有限公司 | Glue tape dressing |
| CN203226950U (en) * | 2013-05-15 | 2013-10-09 | 南京斯瑞奇医疗用品有限公司 | Hydrogel medical dressing |
| CN103463667A (en) * | 2013-05-07 | 2013-12-25 | 哈尔滨工程大学 | Preparation method of nanosilver-carried calcium alginate antibiotic medical dressing |
-
2014
- 2014-01-26 CN CN201410038110.7A patent/CN103768650A/en active Pending
Patent Citations (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090018479A1 (en) * | 2002-06-14 | 2009-01-15 | Hemcon Medical Technologies, Inc. | Absorbable tissue dressing assemblies, systems, and methods formed from hydrophilic polymer sponge structures such as chistosan |
| CN1634607A (en) * | 2003-12-30 | 2005-07-06 | 上海中大科技发展有限公司 | Medical biomaterial and method for manufacturing the same |
| CN1686572A (en) * | 2005-05-13 | 2005-10-26 | 褚省吾 | Ultra strong absorption calcium alginate henatischesis dressing and its preparation method |
| KR20100021108A (en) * | 2008-08-14 | 2010-02-24 | 주식회사 아모메디 | Antibacterial wound dressing laminate and method of preparing the same |
| CN201333128Y (en) * | 2008-12-23 | 2009-10-28 | 上海海洋大学 | Heath care adhesive bandage |
| CN102600019A (en) * | 2012-03-09 | 2012-07-25 | 烟台万利医用品有限公司 | Medical hydrogel dressing and preparation method thereof |
| CN102600018A (en) * | 2012-03-31 | 2012-07-25 | 华南理工大学 | Medical dressing with cooling function and wound healing prompting function and preparation method of medical dressing |
| CN203089549U (en) * | 2013-02-28 | 2013-07-31 | 武汉百美特生物材料科技有限公司 | Glue tape dressing |
| CN103169570A (en) * | 2013-03-06 | 2013-06-26 | 苏州艾美医疗用品有限公司 | Hemostasis bandaid and preparation method thereof |
| CN103463667A (en) * | 2013-05-07 | 2013-12-25 | 哈尔滨工程大学 | Preparation method of nanosilver-carried calcium alginate antibiotic medical dressing |
| CN203226950U (en) * | 2013-05-15 | 2013-10-09 | 南京斯瑞奇医疗用品有限公司 | Hydrogel medical dressing |
Non-Patent Citations (2)
| Title |
|---|
| 刘亦节等: "同轴电纺制备刚性多糖纳米纤维膜", 《功能高分子学报》, vol. 21, no. 1, 31 March 2008 (2008-03-31), pages 20 - 24 * |
| 林晓华等: "新型复合生物抗菌敷料的抗菌强度、吸湿能力及细胞毒性", 《中国组织工程研究》, vol. 17, no. 16, 16 April 2013 (2013-04-16), pages 2905 - 2912 * |
Cited By (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104224446B (en) * | 2014-09-03 | 2018-09-11 | 常州好安生物科技有限公司 | Alginate bandage and its manufacturing method |
| CN104224446A (en) * | 2014-09-03 | 2014-12-24 | 常州好安生物科技有限公司 | Alginate adhesive bandage and manufacturing method of alginate adhesive bandage |
| CN104490519A (en) * | 2014-12-19 | 2015-04-08 | 苏州全润医疗科技有限公司 | Multifunctional medical bandage |
| CN105463700A (en) * | 2015-12-18 | 2016-04-06 | 厦门百美特生物材料科技有限公司 | Spunlace alginate dressing |
| CN106983902A (en) * | 2017-04-18 | 2017-07-28 | 青岛科技大学 | A kind of novel nano composite wound bandage |
| CN107158447A (en) * | 2017-07-06 | 2017-09-15 | 华南理工大学 | A kind of antibacterial zeins dressing with controllable orientation and preparation method thereof |
| CN107158447B (en) * | 2017-07-06 | 2023-11-17 | 华南理工大学 | Antibacterial zein dressing with controllable orientation and preparation method thereof |
| CN107485484A (en) * | 2017-09-01 | 2017-12-19 | 山东汉方生物科技有限公司 | Suitable for general sexual trauma, the wound of chronic trauma patch |
| CN107397974A (en) * | 2017-09-11 | 2017-11-28 | 北京煜煌科技有限公司 | A kind of wound patch for treating chronic trauma |
| CN107789661A (en) * | 2017-09-26 | 2018-03-13 | 华南理工大学 | A kind of hemostatic and antibacterial nanometer film and preparation method thereof |
| CN107789661B (en) * | 2017-09-26 | 2019-12-10 | 华南理工大学 | hemostatic and antibacterial nano-film and preparation method thereof |
| CN108852454A (en) * | 2018-09-07 | 2018-11-23 | 北京健康广济生物技术有限公司 | A kind of hemostasis device for arterial blood gas acquisition |
| CN111481731A (en) * | 2019-01-29 | 2020-08-04 | 中国人民解放军海军特色医学中心 | Collagen-chitosan electrostatic spinning membrane composite alginate anti-seawater soaking application and preparation method thereof |
| CN110841102A (en) * | 2019-11-29 | 2020-02-28 | 青岛农业大学 | Composite nanofiber elastic bandage and preparation method thereof |
| CN111249515A (en) * | 2020-03-11 | 2020-06-09 | 西安工程大学 | Biomedical dressing with antibacterial, anti-inflammatory and wound healing promoting functions and preparation method thereof |
| CN111557790A (en) * | 2020-05-16 | 2020-08-21 | 江苏德鲁克生物科技有限公司 | Antibacterial and disinfectant nanofiber medical dressing |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103768650A (en) | Wound regenerating and repairing bandage and manufacture method thereof | |
| CN100400019C (en) | Emergency wound dressing and its preparation method | |
| CN108014366A (en) | A kind of marine organism material composite hydrogel dressing and preparation method thereof | |
| CN107693835B (en) | Polyvinyl alcohol/collagen/quaternized chitosan electrostatic spinning composite fiber film and preparation method thereof | |
| CN103263694B (en) | Collagen-based dura and preparation method thereof | |
| CN101804218A (en) | Human-body absorbable trauma dressing containing Yunnan white drug powder or Yunnan white drug powder extractive | |
| KR101678656B1 (en) | Preparation method of functionality-enhanced hydrogel mask pack | |
| CN107496972B (en) | Anti-adhesion wet dressing for promoting healing of burn wound and preparation method thereof | |
| CN109731121A (en) | A kind of preparation method of the cellulose containing mesoporous silicon oxide and chitosan combine dressing | |
| CN104383585B (en) | A kind of three-dimensional manometer composite adhesive bandage and preparation and application thereof | |
| CN107510884A (en) | A kind of Silica hydrogel elasticity scar plaster and preparation method thereof | |
| CN109331215A (en) | A kind of medical antibacterial sponge and preparation method thereof | |
| CN105288698A (en) | Calcium alginate composite medical surgical dressing and preparation method thereof | |
| CN103142356A (en) | Cationic wound repair paste and preparation method thereof | |
| CN104383590A (en) | Bamboo chitosan functional dressing and preparation method thereof | |
| CN105640705A (en) | Composite functional surgical dressing | |
| CN105536030A (en) | Dressing chip with hemostasis and restoration promoting functions and preparation method thereof | |
| CN203195854U (en) | Hyaluronic acid group waterproof hemostatic sponge | |
| CN209203745U (en) | A kind of quantum medical trauma adhesive dressing patch | |
| CN203677594U (en) | Wound regeneration and repair bandage | |
| CN111249515A (en) | Biomedical dressing with antibacterial, anti-inflammatory and wound healing promoting functions and preparation method thereof | |
| CN205287034U (en) | Functional medical dressing | |
| CN208081386U (en) | A kind of antibacterial anti-inflammatory combine dressing | |
| WO2019056819A1 (en) | Collagen-loaded alginate medical dressing and preparation method therefor | |
| CN204839932U (en) | Scar dressing |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20140507 |