The utility model content
In view of the above problems, this utility model provides a kind of sticker dressing, is intended to solve the technical problem that existing sticker dressing breathability is poor, action time short, the ingredient utilization rate is low, be unfavorable for wound healing.
For realizing above-mentioned technical problem, the sticker dressing that this utility model provides comprises adhesive substrate and sealer, also is provided with the nanofiber mats of tridimensional network between described adhesive substrate and the sealer.
Described nanofiber mats can obtain with electrospinning process, the nanofiber mats that can prepare heterogeneity, different fibre diameter and different-thickness, go for various application scenarios, such as epidermis hemostasis, promotion wound and ulcer healing, minimizing cicatrix, shaping and beauty etc.
The beneficial effects of the utility model: the nanofiber mats described in this utility model has high specific surface area, high porosity and the tridimensional network that is interconnected, played the organization bracket effect, improved the stickiness of sticker dressing, breathability, comfortableness also can prevent the tissue adhesion, have higher water absorption and moisture-keeping functions, weave cotton cloth or non-woven fabrics is compared with existing, functional nano fiber felt by the method for electrostatic spinning preparation is attached to long action time on the wound, and the stickiness of nanofiber mats, breathability, comfortableness is better, have good bactericidal property and can prevent of the infection of outside antibacterial wound location, can significantly improve the utilization rate of functional ingredient, help accelerating wound.
The specific embodiment
In order to make the purpose of this utility model, technical scheme and advantage clearer,, this utility model is further elaborated below in conjunction with drawings and Examples.Should be appreciated that specific embodiment described herein only in order to explanation this utility model, and be not used in qualification this utility model.
For technical scheme described in the utility model is described, describe below by specific embodiment.
Fig. 1 shows the layer structure of the sticker dressing that this utility model embodiment provides, and only shows the part relevant with this utility model embodiment for convenience of explanation.
The sticker dressing that present embodiment provides comprises adhesive substrate 1 and sealer 2, also is provided with the nanofiber mats 3 of tridimensional network between described adhesive substrate 1 and the sealer 2.
The described nanofiber mats of present embodiment 3 is obtained by method of electrostatic spinning, during concrete operations, in the presence of highfield, by macromolecular solution is imported electrostatic charge, thereby make it jet preparation nanofiber mats in electric field, the tridimensional network that utilizes the nanofiber mats of method of electrostatic spinning preparation to have high specific surface area, high porosity and be interconnected, therefore can be better for the growth of seed cell provides approximate biological intravital microenvironment, improve the success rate of tissue engineering material.With traditional based on weaving cotton cloth or the sticker dressing of non-woven fabrics is compared, utilize the sticker dressing of method of electrostatic spinning preparation can significantly promote the healing rate (average fast 3-5 days of speed of wound healing) of wound, and obviously reduce the formation (the cicatrix size reduces 30-60%) of cicatrix.
When concrete the manufacturing; can be by the composition of the functional ingredient of control; the diameter of nanofiber and the thickness of nanofiber mats; obtain various functional nano fiber felt; thereby make the sticker dressing of various medical applications; the integral thickness of the nanofiber mats 3 that makes usually is 0.01-1mm; the fibre diameter of nanofiber mats 3 is 10-1000nm; its surface is smooth or loose structure; functional ingredient is decided by concrete purposes; nanofiber mats 3 is fitted and is fixed on the adhesive substrate 1; and upper surface is laid the sealer 2 that is used to protect nanofiber mats 3; in use; open sealer 2, nanofiber mats 3 is affixed on target site gets final product.As a kind of concrete selection mode, described adhesive substrate 1 is a pressure sensitive adhesive tape, can also comprise other auxiliary material, and described sealer 2 is a release paper.Present embodiment does not limit the concrete number of plies of nanofiber mats 3, can be single layer structure, can be multiple structure yet, and every layer of nanofiber mats can comprise the functional ingredient that one or more are identical or different.In addition, present embodiment does not limit the concrete shape of sticker dressing yet, can make circle, square, rectangle, ellipse, polygon etc. as required.
The functional ingredient of nanofiber mats can comprise collagen protein, chitosan, alginate, polylactic acid, one or more combinations in the polyurethane, such as the collagen protein nanofiber mats, collagen protein-chitosan nano fiber felt, polyurethane nanofiber felt etc., when preparing the functional nano fiber felt with method of electrostatic spinning, usually do not add cross-linking agent, also can add little amount of crosslinking agent, this cross-linking agent includes but not limited to glutaraldehyde, genipin, oxidized sodium alginate, one or more combinations in 1-ethyl-3-(3-dimethyl aminopropyl)-carbodiimides (EDC) and the N-hydroxy-succinamide (NHS), the addition of this cross-linking agent is 1 of gross mass~100 ‰.
When depositing sticker dressing, monolithic or the dressing of multi-disc sticker can be placed an aseptic sealed packages, open described aseptic sealed packages during use, the dressing of taking-up sticker tears release paper off, directly sticks in target site to get final product.
In a word, compare with traditional sticker dressing, stickiness, breathability, the comfortableness of the sticker dressing that this utility model provides are better, can prevent the tissue adhesion, have higher water absorption and moisture-keeping functions, have good bactericidal property and can prevent of the infection of outside antibacterial wound location, can significantly improve the bioavailability of functional components, can be widely used in the epidermis hemostasis, promote wound and ulcer healing, medical science face-lifting and beauty treatment remove aspects such as speckle.
The above only is preferred embodiment of the present utility model; not in order to restriction this utility model; all any modifications of within spirit of the present utility model and principle, being done, be equal to and replace and improvement etc., all should be included within the protection domain of the present utility model.