CN203195854U - Hyaluronic acid group waterproof hemostatic sponge - Google Patents
Hyaluronic acid group waterproof hemostatic sponge Download PDFInfo
- Publication number
- CN203195854U CN203195854U CN201220433377.2U CN201220433377U CN203195854U CN 203195854 U CN203195854 U CN 203195854U CN 201220433377 U CN201220433377 U CN 201220433377U CN 203195854 U CN203195854 U CN 203195854U
- Authority
- CN
- China
- Prior art keywords
- layer
- hyaluronic acid
- waterproof
- sponge
- release paper
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical group CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 title claims abstract description 40
- 230000002439 hemostatic effect Effects 0.000 title abstract 4
- 229920002674 hyaluronan Polymers 0.000 claims abstract description 36
- 229960003160 hyaluronic acid Drugs 0.000 claims abstract description 36
- 230000002378 acidificating effect Effects 0.000 claims description 8
- 239000000463 material Substances 0.000 claims description 8
- 239000004820 Pressure-sensitive adhesive Substances 0.000 claims description 3
- 150000001875 compounds Chemical class 0.000 claims description 3
- 239000012528 membrane Substances 0.000 claims description 3
- 230000000694 effects Effects 0.000 abstract description 4
- 239000004745 nonwoven fabric Substances 0.000 abstract description 4
- 230000000474 nursing effect Effects 0.000 abstract description 3
- 230000002924 anti-infective effect Effects 0.000 abstract description 2
- 239000010410 layer Substances 0.000 description 40
- 206010052428 Wound Diseases 0.000 description 7
- 208000027418 Wounds and injury Diseases 0.000 description 7
- 238000000034 method Methods 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 230000023597 hemostasis Effects 0.000 description 3
- -1 politef Polymers 0.000 description 3
- 102000008186 Collagen Human genes 0.000 description 2
- 108010035532 Collagen Proteins 0.000 description 2
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 description 2
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 239000011230 binding agent Substances 0.000 description 2
- 210000002744 extracellular matrix Anatomy 0.000 description 2
- 210000000416 exudates and transudate Anatomy 0.000 description 2
- 230000009545 invasion Effects 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 229920002635 polyurethane Polymers 0.000 description 2
- 239000004814 polyurethane Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 230000029663 wound healing Effects 0.000 description 2
- 230000037314 wound repair Effects 0.000 description 2
- SHKUUQIDMUMQQK-UHFFFAOYSA-N 2-[4-(oxiran-2-ylmethoxy)butoxymethyl]oxirane Chemical compound C1OC1COCCCCOCC1CO1 SHKUUQIDMUMQQK-UHFFFAOYSA-N 0.000 description 1
- JAYKZPAAEDTMRI-UHFFFAOYSA-N CCCCCCCC.[O] Chemical compound CCCCCCCC.[O] JAYKZPAAEDTMRI-UHFFFAOYSA-N 0.000 description 1
- 229920001661 Chitosan Polymers 0.000 description 1
- 206010063560 Excessive granulation tissue Diseases 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 241001597008 Nomeidae Species 0.000 description 1
- 239000002033 PVDF binder Substances 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 206010042566 Superinfection Diseases 0.000 description 1
- 206010048038 Wound infection Diseases 0.000 description 1
- 235000011054 acetic acid Nutrition 0.000 description 1
- 239000000783 alginic acid Substances 0.000 description 1
- 235000010443 alginic acid Nutrition 0.000 description 1
- 229920000615 alginic acid Polymers 0.000 description 1
- 229960001126 alginic acid Drugs 0.000 description 1
- 150000004781 alginic acids Chemical class 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 229940030225 antihemorrhagics Drugs 0.000 description 1
- 230000003796 beauty Effects 0.000 description 1
- 210000000589 cicatrix Anatomy 0.000 description 1
- 235000015165 citric acid Nutrition 0.000 description 1
- 210000002808 connective tissue Anatomy 0.000 description 1
- 208000021921 corneal disease Diseases 0.000 description 1
- 238000010041 electrostatic spinning Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 210000001126 granulation tissue Anatomy 0.000 description 1
- 230000000025 haemostatic effect Effects 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 230000036571 hydration Effects 0.000 description 1
- 238000006703 hydration reaction Methods 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000002052 molecular layer Substances 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 229950000845 politef Drugs 0.000 description 1
- 229920000747 poly(lactic acid) Polymers 0.000 description 1
- 229920001610 polycaprolactone Polymers 0.000 description 1
- 239000004632 polycaprolactone Substances 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 239000004626 polylactic acid Substances 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920002981 polyvinylidene fluoride Polymers 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
- 239000002356 single layer Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
Images
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- Materials For Medical Uses (AREA)
Abstract
The utility model relates to a dressing for medical nursing or surgical department, and particularly to a hyaluronic acid group waterproof hemostatic sponge. The hyaluronic acid group waterproof hemostatic sponge is composed of a nonwoven fabric layer, a waterproof ventilated layer, a hyaluronic acid sponge layer and a release paper layer. The nonwoven fabric layer is provided at the topmost layer. The waterproof ventilated layer is compounded at the bottom surface of the nonwoven fabric layer. The hyaluronic acid sponge layer is adhibited on the bottom surface of the waterproof ventilated layer and furthermore the area of the hyaluronic acid sponge layer is smaller than that of the waterproof ventilated layer. The release paper covers the bottom surface of the hyaluronic acid sponge layer. The edge of the release paper is bound with the edge of the waterproof ventilated layer at the periphery of the hyaluronic acid sponge layer for closing the hyaluronic acid sponge layer at the inner part. The hyaluronic acid group waterproof hemostatic sponge has the following advantages: one-time adhibition, high convenience in use, high wound surface recovering effect, high waterproof performance and high anti-infection capability.
Description
Technical field
This utility model relates to medical treatment and nursing or surgery dressing, specifically is a kind of hyaluronic acid waterproof sthptic sponge.
Background technology
Hemostasis is an important step of emergency medical service treatment; sudden trauma, the medium wound of patient's operation process in the vehicle accident; all need carry out quick-acting haemostatic powder; and harsh climate environmental factors (tsunami, earthquake etc.); and the wound of initiation during complicated burst war (sea, land battle etc.); not only require simple hemostasis, for the protection of wound with prevent again subinfection to seem particularly important.
Use sthptic sponge comparatively widely at present clinically, as gelfoam and collagen protein sponge, because its good biocompatibility is widely used.But all have several shortcomings, all need assist other dressing that it is carried out bondage and fix, in changing nursing process, the individual uses very inconvenient; Suppress the generation of cicatrix simultaneously for the later stage wound healing, also do not have very special curative effect; Common single layer structure can not stop the water of external source environment and the invasion of microorganism, increases the wound infection probability.
Hyaluronic acid extensively is present in animal and human's body connective tissue, and it plays crucial effect as the main component that constitutes extracellular matrix (ECM) and intercellular matrix (ICM) in the treatment that promotes wound healing and inhibition cicatrization.The characteristics of hyaluronic acid maximum are water-retaining property and film property; wherein the 1g hyaluronic acid can be in conjunction with the water up to 10000 times of sole masses; form the binder of similar hydration molecular layer after the moisture absorption rapidly; new that form, the fragile granulation tissue of protection; reduce cicatrization; the hydrate molecule layer also can effectively stop inoculating microbe to be invaded simultaneously, and wound is caused superinfection.At present, hyaluronic acid is in wound repair, the cornea disease, and beauty and shaping is implanted, and fields such as cartilaginous tissue filling are of many uses.
Summary of the invention
Technical problem to be solved in the utility model is, provides a kind of and can disposablely notice, hyalomitome acidic group waterproof easy to use, that wound repair is effective, waterproof and anti-infection ability are strong is styptic sponge used.
Hyalomitome acidic group waterproof sthptic sponge of the present utility model is made up of for four layers nonwoven layer, waterproof ventilative layer, hyaluronic acid sponge layer and release paper; Described nonwoven layer is positioned at the superiors, and waterproof ventilative layer is compound in the bottom surface of nonwoven layer; Hyaluronic acid sponge layer fits in the waterproof ventilative layer bottom surface, and the area of hyaluronic acid sponge layer is less than waterproof ventilative layer; Release paper covers on the bottom surface of hyaluronic acid sponge layer, and the edge of release paper is bonding with the waterproof ventilative layer edge that is positioned at around the hyaluronic acid sponge layer by pressure sensitive adhesive, in hyaluronic acid sponge layer is enclosed in.
Described hyaluronic acid sponge layer is for comprising hyaluronic sponge shape material.
Described waterproof ventilative layer exceeds hyaluronic acid sponge layer edge 3-4cm.
Described waterproof ventilative layer is to be the polymeric material nano fibrous membrane.
The effect that this utility model is positive: 1, the hyaluronic acid of spongy layer, form the spatial network system of hole homogeneous, hemostasis can form a hydrate molecule binder behind the absorption transudate rapidly, can not only remove exudate fast, can provide moistening healing environment for wound surface simultaneously.2, waterproof ventilative layer directly sprays on the non-woven fabrics, frivolous softness, and good permeability, nano level duct can effectively stop the invasion of extraneous moisture and antibacterial, and the protection wound is exempted from infected.3, adhesion function is arranged, disposable sticking need not bondage, can be from line operate, and easy to use.
Description of drawings
Fig. 1 is overall structure sketch map of the present utility model;
Fig. 2 is cross section structure sketch map of the present utility model.
The specific embodiment
As shown in the figure, this hyalomitome acidic group waterproof sthptic sponge is made up of for 4 four layers nonwoven layer 1, waterproof ventilative layer 2, hyaluronic acid sponge layer 3 and release paper; Described nonwoven layer 1 is positioned at the superiors, and waterproof ventilative layer 2 is compound in the bottom surface of nonwoven layer 1; Hyaluronic acid sponge layer 3 fits in waterproof ventilative layer 2 bottom surfaces, and the area of hyaluronic acid sponge layer 3 is less than waterproof ventilative layer 2; Release paper 4 covers on the bottom surface of hyaluronic acid sponge layer 3, and the edge of release paper 4 is bonding with waterproof ventilative layer 2 edges that are positioned at around the hyaluronic acid sponge layer by pressure sensitive adhesive, in hyaluronic acid sponge layer 3 is enclosed in.
The hyaluronic acid sponge layer is and the direct contact layer of wound, its preparation method is: with main material hyaluronic acid and gelatin, collagen protein, chitosan, alginic acid and derivant thereof, polylactic acid, polyvinylpyrrolidone, glycerol, lactic acid, acetic acid, citric acid, 1,4-butanediol diglycidyl ether, 1,2, in 7, the 8-bicyclic oxygen octane one or more mix the back and adopt freeze-drying or other proper method to make spongy.Waterproof ventilative layer is the nano fibrous membrane that makes through through electrostatic spinning technique, the superfine fibre that polymeric material makes as pull strength by electrostatic force.It is fine etc. that its main material can be polycaprolactone, politef, polyethylene, polyvinylidene fluoride, polyurethane or polypropylene, is best with polyurethane material.
Claims (4)
1. a hyalomitome acidic group waterproof sthptic sponge is characterized in that: be made up of for (4) four layers nonwoven layer (1), waterproof ventilative layer (2), hyaluronic acid sponge layer (3) and release paper; Described nonwoven layer (1) is positioned at the superiors, and waterproof ventilative layer (2) is compound in the bottom surface of nonwoven layer (1); Hyaluronic acid sponge layer (3) fits in waterproof ventilative layer (2) bottom surface, and the area of hyaluronic acid sponge layer (3) is less than waterproof ventilative layer (2); Release paper (4) covers on the bottom surface of hyaluronic acid sponge layer (3), and the edge of release paper (4) is bonding with waterproof ventilative layer (2) edge that is positioned at around the hyaluronic acid sponge layer by pressure sensitive adhesive, in hyaluronic acid sponge layer (3) is enclosed in.
2. hyalomitome acidic group waterproof sthptic sponge according to claim 1, it is characterized in that: described hyaluronic acid sponge layer is for comprising hyaluronic sponge shape material.
3. hyalomitome acidic group waterproof sthptic sponge according to claim 1, it is characterized in that: described waterproof ventilative layer exceeds hyaluronic acid sponge layer edge 3-4cm.
4. hyalomitome acidic group waterproof sthptic sponge according to claim 1, it is characterized in that: described waterproof ventilative layer is to be the polymeric material nano fibrous membrane.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201220433377.2U CN203195854U (en) | 2012-08-29 | 2012-08-29 | Hyaluronic acid group waterproof hemostatic sponge |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201220433377.2U CN203195854U (en) | 2012-08-29 | 2012-08-29 | Hyaluronic acid group waterproof hemostatic sponge |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203195854U true CN203195854U (en) | 2013-09-18 |
Family
ID=49139998
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201220433377.2U Expired - Lifetime CN203195854U (en) | 2012-08-29 | 2012-08-29 | Hyaluronic acid group waterproof hemostatic sponge |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN203195854U (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103705971A (en) * | 2013-12-19 | 2014-04-09 | 褚加冕 | Composite hyaluronic acid (HA) wound dressing |
| CN105686903A (en) * | 2014-12-16 | 2016-06-22 | 准讯生医股份有限公司 | Long-acting type paster dressing structure |
| CN105816903A (en) * | 2016-05-12 | 2016-08-03 | 东华大学 | Drug-loaded hyaluronic acid nanofiber composite dressing and preparation method thereof |
| CN114452081A (en) * | 2022-02-22 | 2022-05-10 | 河南省洛阳正骨医院（河南省骨科医院） | Rapid hemostasis application |
-
2012
- 2012-08-29 CN CN201220433377.2U patent/CN203195854U/en not_active Expired - Lifetime
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103705971A (en) * | 2013-12-19 | 2014-04-09 | 褚加冕 | Composite hyaluronic acid (HA) wound dressing |
| CN103705971B (en) * | 2013-12-19 | 2016-01-20 | 褚加冕 | A kind of composite transparent matter acid wound dressing |
| CN105686903A (en) * | 2014-12-16 | 2016-06-22 | 准讯生医股份有限公司 | Long-acting type paster dressing structure |
| CN105816903A (en) * | 2016-05-12 | 2016-08-03 | 东华大学 | Drug-loaded hyaluronic acid nanofiber composite dressing and preparation method thereof |
| CN114452081A (en) * | 2022-02-22 | 2022-05-10 | 河南省洛阳正骨医院（河南省骨科医院） | Rapid hemostasis application |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C41 | Transfer of patent application or patent right or utility model | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20160803 Address after: 212132 Zhenjiang province Jiangsu city Zhenjiang District No. 38 Dingmao pan Zong Lu Patentee after: JIANGSU CHANGJIYONG BIOTECHNOLOGY Co.,Ltd. Address before: Leng Yu Lu Dantu high tech Development Zone in Jiangsu Province, Zhenjiang City, No. 168, 212143 Patentee before: Jiangsu HIDream Biotechnology Co.,Ltd. |
|
| CX01 | Expiry of patent term |
Granted publication date: 20130918 |
|
| CX01 | Expiry of patent term |