CN103768449A

CN103768449A - Medicine for treating psoriasis

Info

Publication number: CN103768449A
Application number: CN201410055894.4A
Authority: CN
Inventors: 陈海林
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-02-19
Filing date: 2014-02-19
Publication date: 2014-05-07
Anticipated expiration: 2034-02-19
Also published as: CN103768449B

Abstract

The invention relates to a medicine for treating psoriasis. The medicine is prepared from the following substances in a weight ratio: astragalus membranaceus, rauvolfia verticillata, divaricate saposhnikovia root, tomentoseflower larkspour root, moutan bark, dandelion, cortex phellodendri, atractylodes, rhizoma nelumbinis, purslane, lithospermum, coptidis rhizoma, dictamni cortex, cortex lycii radicis, smilax riparia, liquorice, silkworm larva, mongolian snakegourd root, red peony root, rhizoma anemarrhenae, spatholobus suberctu, fructus cnidii, broom cypress fruit, deep-fried bighead atractylodes rhizome, coix seed, zornia diphylla pers, zaocys dhumnade, cicada slough, scorpion, nidus vespae, tortoise shell and turtle shell. The medicine for treating psoriasis has the effects of clearing heat and cooling blood, dispelling wind and relieving itching, nourishing dryness and yin, eliminating dampness and removing stasis, can be used for effectively treating psoriasis caused by wind formation due to blood heat, wind formation due to blood deficiency, depression accumulation due to wind pathogen and the like.

Description

A kind of antipsoriatics thing

Technical field

The present invention relates to tcm field, specifically, relate to a kind of antipsoriatics thing.

Background technology

Psoriasis is a kind of common obstinate dermatosis, its feature is respectively the whole skins such as head, item, elbow, knee joint and tail sacrum and occurs erythematous eruption, merge in flakes, pachylosis, shape is symmetrical conventionally as lichen, and texture is deepened, violent sufferings, be more common in adult, also involve clinically in recent years child and teenager.

Summary of the invention

The object of this invention is to provide a kind of antipsoriatics thing.

In order to realize object of the present invention, the invention provides a kind of antipsoriatics thing, it is made up of the material of following weight proportioning: Radix Astragali 25-35 part, trident tiger 30-40 part, Radix Saposhnikoviae 10-20 part, Rhizoma Arisaematis 25-35 part, Cortex Moutan 10-20 part, Herba Taraxaci 26-31 part, Cortex Phellodendri 10-20 part, Rhizoma Atractylodis 10-20 part, Nodus Nelumbinis Rhizomatis 25-40 part, Herba Portulacae 25-35 part, Radix Arnebiae (Radix Lithospermi) 15-25 part, Rhizoma Coptidis 10-20 part, Cortex Dictamni 15-27 part, Cortex Lycii 15-27 part, Radix et Rhizoma Smilacis Ripariae 30-40 part, Radix Glycyrrhizae 10-20 part, Bombyx Batryticatus 15-25 part, Radix Trichosanthis 15-25 part, Radix Paeoniae Rubra 15-25 part, Rhizoma Anemarrhenae 15-25 part, Caulis Spatholobi 15-25 part, Fructus Cnidii 15-25 part, Fructus Kochiae 15-25 part, Rhizoma Atractylodis Macrocephalae preparata 15-25 part, Semen Coicis 25-35 part, Herba Zornia Diphyllae 30-40 part, Zaocys 10-20 part, Periostracum Cicadae 10-20 part, Scorpio 5-15 part, Nidus Vespae 10-20 part, Carapax Et Plastrum Testudinis 25-35 part and Carapax Trionycis 25-35 part.

Preferably, antipsoriatics thing of the present invention is made up of the material of following weight proportioning: 30 parts of the Radixs Astragali, 40 parts of trident tigers, 15 parts of Radix Saposhnikoviaes, 35 parts of Rhizoma Arisaematis, 15 parts of Cortex Moutans, 30 parts of Herba Taraxacis, 15 parts of Cortex Phellodendris, 15 parts of Rhizoma Atractylodis, 35 parts of Nodus Nelumbinis Rhizomatis, 30 parts of Herba Portulacaes, 20 parts of Radix Arnebiae (Radix Lithospermi)s, 15 parts of Rhizoma Coptidis, 20 parts of Cortex Dictamni, 20 parts of Cortex Lycii, 40 parts of Radix et Rhizoma Smilacis Ripariae, 15 parts, Radix Glycyrrhizae, 20 parts of Bombyx Batryticatus, 20 parts of Radix Trichosanthis, 20 parts of Radix Paeoniae Rubra, 20 parts of the Rhizoma Anemarrhenaes, 20 parts of Caulis Spatholobis, 20 parts of Fructus Cnidiis, 20 parts of the Fructus Kochiae, 20 parts of Rhizoma Atractylodis Macrocephalae preparatas, 30 parts of Semen Coiciss, 40 parts of Herba Zornia Diphyllae, 15 parts of Zaocyss, 15 parts of Periostracum Cicadaes, 10 parts of Scorpios, 15 parts, Nidus Vespae, 25 parts of 25 parts of Carapax Et Plastrum Testudiniss and Carapax Trionycis.

More preferably, described medicine can be tablet, dispersible tablet, buccal tablet, instant, unguentum or capsule.

As used herein,

Rhizoma Arisaematis

Medical material Ji Yuan: be the plant of warm ground of Bryaceae rhodobryum spp plant great Ye moss.

Latin plant name: Rhodobryum giganteum (Schwaegr.) Par[Bryum giganteum Schwaegr.; Mnium giganteum Schwaegr.]

Nature and flavor: pungent; Bitter; Flat

Function cures mainly: tranquilizing by nourishing the heart; Liver heat removing and eyesight improving.Main severe palpitation; Neurasthenia; Conjunctival congestion and swelling pain; Coronary heart disease; Hypertension etc.

Trident tiger

[base is former] is stem, leaf or the root of Rutaceae Evodia plant Foliumet Ramulus Evodiae.

[former plant] Foliumet Ramulus Evodiae Eoodialepta (Spteng.) Merr.[ller lepta Spreng.]

Radix et Rhizoma Smilacis Ripariae

[base is former] is the root and rhizome of Liliaceae greenbrier cornel platymiscium Radix et Rhizoma Smilacis Ripariae.

[former plant] Radix et Rhizoma Smilacis Ripariae Smilax ripariaA.DC.

Herba Zornia Diphyllae

Latin formal name used at school Zomia gibbosa Spanog.

Plant kingdom of boundary door Angiospermae guiding principle Dicotyledoneae

The original perianth subclass of subclass order Rosales suborder Flos Rosae Multiflorae suborder

Herba Aeschynonenes Indicae family of pulse family subfamily Papillionoideae family of section belongs to Herba Zornia Diphyllae and belongs to

In compositions of the present invention, in side, Nodus Nelumbinis Rhizomatis, trident tiger, Rhizoma Arisaematis, Herba Zornia Diphyllae, Radix et Rhizoma Smilacis Ripariae are monarch drug altogether, the Radix Astragali, Herba Portulacae, Semen Coicis, Herba Taraxaci, Carapax Et Plastrum Testudinis, the auxiliary monarch drug of Carapax Trionycis are ministerial drug, Cortex Dictamni, Cortex Lycii, the Rhizoma Anemarrhenae, Radix Paeoniae Rubra, Fructus Cnidii, the Fructus Kochiae, Rhizoma Atractylodis Macrocephalae preparata, Caulis Spatholobi, Bombyx Batryticatus, Radix Trichosanthis are adjuvant drug, Radix Saposhnikoviae, Cortex Moutan, Cortex Phellodendri, Rhizoma Atractylodis, Radix Arnebiae (Radix Lithospermi), Rhizoma Coptidis, Radix Glycyrrhizae, Zaocys, Periostracum Cicadae, Scorpio, Nidus Vespae are for making medicine, so medical material is brought into play drug effect jointly according to the principle of monarch.

Antipsoriatics thing clearing away heat and cooling blood of the present invention, search wind antipruritic, moisturize yin nourishing, damp eliminating blood stasis dispelling, can effectively treat blood hot air wind producing disease, wind syndrome due to blood-deficiency disease, ailment said due to cold or exposure and accumulate the psoriasis that melancholia etc. causes.

The specific embodiment

Embodiment 1:

Take 30 grams of the Radixs Astragali, 40 grams of trident tigers, 15 grams of Radix Saposhnikoviaes, 35 grams of Rhizoma Arisaematis, 15 grams of Cortex Moutans, 30 grams of Herba Taraxacis, 15 grams of Cortex Phellodendris, 15 grams of Rhizoma Atractylodis, 35 grams of Nodus Nelumbinis Rhizomatis, 30 grams of Herba Portulacaes, 20 grams of Radix Arnebiae (Radix Lithospermi)s, 15 grams of Rhizoma Coptidis, 20 grams of Cortex Dictamni, 20 grams of Cortex Lycii, 40 grams of Radix et Rhizoma Smilacis Ripariae, 15 grams, Radix Glycyrrhizae, 20 grams of Bombyx Batryticatus, 20 grams of Radix Trichosanthis, 20 grams of Radix Paeoniae Rubra, 20 grams of the Rhizoma Anemarrhenaes, 20 grams of Caulis Spatholobis, 20 grams of Fructus Cnidiis, 20 grams of the Fructus Kochiae, 20 grams of Rhizoma Atractylodis Macrocephalae preparatas, 30 grams of Semen Coiciss, 40 grams of Herba Zornia Diphyllae, 15 grams of Zaocyss, 15 grams of Periostracum Cicadaes, 10 grams of Scorpios, 15 grams, Nidus Vespae, 25 grams of 25 grams of Carapax Et Plastrum Testudiniss and Carapax Trionycis, add 60000 milliliters, water, in the flask that condenser is housed, at 90 ℃, heat 5 hours, filter, filtrate is decoction of the present invention.

Experimental example

Select within 2012, between year December of January-2013, diagnose medical patient 60 examples to me, wherein male 30 examples, female's 30 examples; Age reckling 26 years old, the maximum 55 years old; The shortest person of stadium January, elder 2 years; Person's 12 examples that skin starts from extremity, head 16 examples, facial person's 3 examples, trunk person 8 examples, whole body person 10 examples, buttocks person 11 examples; Acute attack 21 examples, chronic disease person 35 examples, not clear person's 4 examples.After diagnosing, wherein erythroderma type psoriatic 12 examples, pustule type psoriatic 11 examples, acute psoriasis punctata patient 19 examples of homeliness type, the chronic patch shape of homeliness type psoriatic 18 examples.

Use the decoction of preparation in embodiment 1 to treat, every day 1 time, each oral 100 milliliters, continuous 2 weeks.

The criterion of clinical therapeutic efficacy is:

Clinical cure: skin lesion disappears completely or only stays several unconspicuous point erythra.

Effective: erythra more than 90% disappears, and pruritus obviously alleviates.

Effective: between deflorescence 40%-90%, pruritus alleviates.

Invalid: deflorescence is not obvious or increase the weight of.

Through treatment, find in 60 routine patients clinical cure 10 examples, effective 32 examples, effective 18 examples, invalid 0 example.And in therapeutic process, do not find the significantly untoward reaction such as feeling sick appears in patient, vomiting.

Model case

Zhang, man, 38 years old, Dian Shang town, Lucheng City, Shanxi peasant.Before 1 year because of heavy cold, after hyperpyrexia, general psoriasis of whole body, extremity, head, whole body have tinea.Go to a doctor and use hormone to treat in Duo Jia hospital, all invalid.It is medical that in August, 2012, I diagnosed, and uses the decoction of preparation in embodiment 1 to treat, every day 1 time, each oral 100 milliliters, continuous 2 weeks.Observe whole body and have no obvious tinea, also without the sensation of any pruritus, also without the obvious erythra of discovery.Go home to be normally engaged in agriculture, carried out with examining 3 months subsequently every months, also do not find the sign of recurrence.

Hu, man, 52 years old, Taiyuan, Shanxi people, civil servant.Happen suddenly the Spring Festival in 2012 in the red macule of Head And Face, decortication, accompanies violent pruritus in a large number; Be diagnosed as psoriasis in specialist hospital, with after the treatment of Western medicine hormones, the state of an illness does not take a turn for the better, and spreads to whole body, and extremity are in a bad way, and have a strong impact on work and life.Treat to this clinic in December, 2012 is well-known.Use the decoction of preparation in embodiment 1 to treat, every day 1 time, each oral 100 milliliters, continuous 2 weeks.Observation General Symptoms disappears, without the sensation of any pruritus, also without finding obvious erythra.Carry out phone with examining 3 months subsequently every months, also do not find the sign of recurrence.

Liu so-and-so, female, 43 years old, urban district, Lucheng City, Shanxi textile female worker.Well-knownly treat to this clinic in February, 2013.Patient suffers from erythroderma type psoriasis, states case history more than 1 year, never stops treatment, and various big hospital was all controlled, all invalid and return.All the time thoroughly do not cure.Patient does not have tinea except head, face, and shirtfront, back tinea are less, extremity especially severe, and summer, sky heat dare not be exposed extremity.Use the decoction of preparation in embodiment 1 to treat, every day 1 time, each oral 100 milliliters, continuous 2 weeks.Observation General Symptoms disappears, without the sensation of any pruritus, also without finding obvious tinea.Carry out phone with examining 3 months subsequently every months, also do not find the sign of recurrence.

Poplar, female, 29 years old, Wei Zi people from town, Lucheng City, Shanxi, patient suffers from psoriasis a year and a half, goes to a doctor invalid in Duo Jia hospital, and the countless folk prescription prescriptions of rear use are not all cured, and treat to this clinic in June, 2013.Use the decoction of preparation in embodiment 1 to treat, every day 1 time, each oral 100 milliliters, continuous 2 weeks.Pruritus stops, and silver bits disappear.Carry out phone with examining 3 months subsequently every months, also do not find the sign of recurrence.

Claims

1. an antipsoriatics thing, it is characterized in that, it is made up of the material of following weight proportioning: Radix Astragali 25-35 part, trident tiger 30-40 part, Radix Saposhnikoviae 10-20 part, Rhizoma Arisaematis 25-35 part, Cortex Moutan 10-20 part, Herba Taraxaci 26-31 part, Cortex Phellodendri 10-20 part, Rhizoma Atractylodis 10-20 part, Nodus Nelumbinis Rhizomatis 25-40 part, Herba Portulacae 25-35 part, Radix Arnebiae (Radix Lithospermi) 15-25 part, Rhizoma Coptidis 10-20 part, Cortex Dictamni 15-27 part, Cortex Lycii 15-27 part, Radix et Rhizoma Smilacis Ripariae 30-40 part, Radix Glycyrrhizae 10-20 part, Bombyx Batryticatus 15-25 part, Radix Trichosanthis 15-25 part, Radix Paeoniae Rubra 15-25 part, Rhizoma Anemarrhenae 15-25 part, Caulis Spatholobi 15-25 part, Fructus Cnidii 15-25 part, Fructus Kochiae 15-25 part, Rhizoma Atractylodis Macrocephalae preparata 15-25 part, Semen Coicis 25-35 part, Herba Zornia Diphyllae 30-40 part, Zaocys 10-20 part, Periostracum Cicadae 10-20 part, Scorpio 5-15 part, Nidus Vespae 10-20 part, Carapax Et Plastrum Testudinis 25-35 part and Carapax Trionycis 25-35 part.

2. antipsoriatics thing according to claim 1, it is characterized in that, it is made up of the material of following weight proportioning: 30 parts of the Radixs Astragali, 40 parts of trident tigers, 15 parts of Radix Saposhnikoviaes, 35 parts of Rhizoma Arisaematis, 15 parts of Cortex Moutans, 30 parts of Herba Taraxacis, 15 parts of Cortex Phellodendris, 15 parts of Rhizoma Atractylodis, 35 parts of Nodus Nelumbinis Rhizomatis, 30 parts of Herba Portulacaes, 20 parts of Radix Arnebiae (Radix Lithospermi)s, 15 parts of Rhizoma Coptidis, 20 parts of Cortex Dictamni, 20 parts of Cortex Lycii, 40 parts of Radix et Rhizoma Smilacis Ripariae, 15 parts, Radix Glycyrrhizae, 20 parts of Bombyx Batryticatus, 20 parts of Radix Trichosanthis, 20 parts of Radix Paeoniae Rubra, 20 parts of the Rhizoma Anemarrhenaes, 20 parts of Caulis Spatholobis, 20 parts of Fructus Cnidiis, 20 parts of the Fructus Kochiae, 20 parts of Rhizoma Atractylodis Macrocephalae preparatas, 30 parts of Semen Coiciss, 40 parts of Herba Zornia Diphyllae, 15 parts of Zaocyss, 15 parts of Periostracum Cicadaes, 10 parts of Scorpios, 15 parts, Nidus Vespae, 25 parts of 25 parts of Carapax Et Plastrum Testudiniss and Carapax Trionycis.

3. antipsoriatics thing according to claim 1 and 2, is characterized in that, described medicine can be tablet, dispersible tablet, buccal tablet, instant, unguentum or decoction.