CN103768449B

CN103768449B - A kind of antipsoriatics thing

Info

Publication number: CN103768449B
Application number: CN201410055894.4A
Authority: CN
Inventors: 陈海林
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-02-19
Filing date: 2014-02-19
Publication date: 2016-03-09
Anticipated expiration: 2034-02-19
Also published as: CN103768449A

Abstract

The present invention relates to a kind of antipsoriatics thing, it is made up of the material of following weight proportioning: the Radix Astragali, Rauvolfia verticillata, Radix Saposhnikoviae, Rhizoma Arisaematis, Cortex Moutan, Herba Taraxaci, Cortex Phellodendri, Rhizoma Atractylodis, Nodus Nelumbinis Rhizomatis, Herba Portulacae, Radix Arnebiae (Radix Lithospermi), Rhizoma Coptidis, Cortex Dictamni, Cortex Lycii, Radix et Rhizoma Smilacis Ripariae, Radix Glycyrrhizae, Bombyx Batryticatus, Radix Trichosanthis, Radix Paeoniae Rubra, the Rhizoma Anemarrhenae, Caulis Spatholobi, Fructus Cnidii, the Fructus Kochiae, Rhizoma Atractylodis Macrocephalae preparata, Semen Coicis, Herba Zornia Diphyllae, Zaocys, Periostracum Cicadae, Scorpio, Nidus Vespae, Carapax Et Plastrum Testudinis and Carapax Trionycis.Antipsoriatics thing clearing away heat and cooling blood of the present invention, search wind antipruritic, moisturize yin nourishing, damp eliminating blood stasis dispelling, the psoriasis that effectively can treat blood hot air wind producing disease, wind syndrome due to blood-deficiency disease, ailment said due to cold or exposure accumulate melancholia etc. is caused.

Description

A kind of antipsoriatics thing

Technical field

The present invention relates to tcm field, specifically, relate to a kind of antipsoriatics thing.

Background technology

Psoriasis is a kind of common obstinate dermatosis, its feature is respectively the whole skins such as head, item, elbow, knee joint and tail sacrum and occurs erythematous eruption, merge in flakes, pachylosis, shape is as usual in lichen symmetrically, and texture is deepened, violent sufferings, be more common in adult, also involve Children and teenager clinically in recent years.

Summary of the invention

The object of this invention is to provide a kind of antipsoriatics thing.

In order to realize object of the present invention, the invention provides a kind of antipsoriatics thing, it is made up of the material of following weight proportioning: Radix Astragali 25-35 part, Rauvolfia verticillata 30-40 part, Radix Saposhnikoviae 10-20 part, Rhizoma Arisaematis 25-35 part, Cortex Moutan 10-20 part, Herba Taraxaci 26-31 part, Cortex Phellodendri 10-20 part, Rhizoma Atractylodis 10-20 part, Nodus Nelumbinis Rhizomatis 25-40 part, Herba Portulacae 25-35 part, Radix Arnebiae (Radix Lithospermi) 15-25 part, Rhizoma Coptidis 10-20 part, Cortex Dictamni 15-27 part, Cortex Lycii 15-27 part, Radix et Rhizoma Smilacis Ripariae 30-40 part, Radix Glycyrrhizae 10-20 part, Bombyx Batryticatus 15-25 part, Radix Trichosanthis 15-25 part, Radix Paeoniae Rubra 15-25 part, Rhizoma Anemarrhenae 15-25 part, Caulis Spatholobi 15-25 part, Fructus Cnidii 15-25 part, Fructus Kochiae 15-25 part, Rhizoma Atractylodis Macrocephalae preparata 15-25 part, Semen Coicis 25-35 part, Herba Zornia Diphyllae 30-40 part, Zaocys 10-20 part, Periostracum Cicadae 10-20 part, Scorpio 5-15 part, Nidus Vespae 10-20 part, Carapax Et Plastrum Testudinis 25-35 part and Carapax Trionycis 25-35 part.

Preferably, antipsoriatics thing of the present invention is made up of the material of following weight proportioning: the Radix Astragali 30 parts, Rauvolfia verticillata 40 parts, Radix Saposhnikoviae 15 parts, Rhizoma Arisaematis 35 parts, Cortex Moutan 15 parts, Herba Taraxaci 30 parts, Cortex Phellodendri 15 parts, Rhizoma Atractylodis 15 parts, Nodus Nelumbinis Rhizomatis 35 parts, Herba Portulacae 30 parts, Radix Arnebiae (Radix Lithospermi) 20 parts, Rhizoma Coptidis 15 parts, Cortex Dictamni 20 parts, Cortex Lycii 20 parts, Radix et Rhizoma Smilacis Ripariae 40 parts, 15 parts, Radix Glycyrrhizae, Bombyx Batryticatus 20 parts, Radix Trichosanthis 20 parts, Radix Paeoniae Rubra 20 parts, the Rhizoma Anemarrhenae 20 parts, Caulis Spatholobi 20 parts, Fructus Cnidii 20 parts, the Fructus Kochiae 20 parts, Rhizoma Atractylodis Macrocephalae preparata 20 parts, Semen Coicis 30 parts, Herba Zornia Diphyllae 40 parts, Zaocys 15 parts, Periostracum Cicadae 15 parts, Scorpio 10 parts, 15 parts, Nidus Vespae, Carapax Et Plastrum Testudinis 25 parts and Carapax Trionycis 25 parts.

More preferably, described medicine can be tablet, dispersible tablet, buccal tablet, rapidly dissolving tablet, unguentum or capsule.

As used herein,

Rhizoma Arisaematis

Medical material Ji Yuan: for Bryaceae rhodobryum spp plant warms up the plant of ground great Ye moss.

Latin plant name: Rhodobryumgiganteum (Schwaegr.) Par [BryumgiganteumSchwaegr.; MniumgiganteumSchwaegr.]

Nature and flavor: pungent; Bitter; Flat

Function cures mainly: tranquilizing by nourishing the heart; Liver heat removing and eyesight improving.Main severe palpitation; Neurasthenia; Conjunctival congestion and swelling pain; Coronary heart disease; Hypertension etc.

Rauvolfia verticillata

The stem that [base is former] is Rutaceae Evodia plant Foliumet Ramulus Evodiae, leaf or root.

[former plant] Foliumet Ramulus Evodiae Eoodialepta (Spteng.) Merr. [llerleptaSpreng.]

Radix et Rhizoma Smilacis Ripariae

[base is former] is the root and rhizome of Liliaceae greenbrier cornel platymiscium Radix et Rhizoma Smilacis Ripariae.

[former plant] Radix et Rhizoma Smilacis Ripariae SmilaxripariaA.DC.

Herba Zornia Diphyllae

Classification system ZomiagibbosaSpanog.

Plant kingdom of boundary door Angiospermae guiding principle Dicotyledoneae

Subclass original perianth subclass order Rosales suborder Flos Rosae Multiflorae suborder

Herba Aeschynonenes Indicae race of pulse family subfamily Papillionoideae race of section belongs to Herba Zornia Diphyllae and belongs to

In the present compositions, in side, Nodus Nelumbinis Rhizomatis, Rauvolfia verticillata, Rhizoma Arisaematis, Herba Zornia Diphyllae, Radix et Rhizoma Smilacis Ripariae are monarch drug altogether, the Radix Astragali, Herba Portulacae, Semen Coicis, Herba Taraxaci, Carapax Et Plastrum Testudinis, Carapax Trionycis assist monarch drug to be ministerial drug, Cortex Dictamni, Cortex Lycii, the Rhizoma Anemarrhenae, Radix Paeoniae Rubra, Fructus Cnidii, the Fructus Kochiae, Rhizoma Atractylodis Macrocephalae preparata, Caulis Spatholobi, Bombyx Batryticatus, Radix Trichosanthis are adjuvant drug, Radix Saposhnikoviae, Cortex Moutan, Cortex Phellodendri, Rhizoma Atractylodis, Radix Arnebiae (Radix Lithospermi), Rhizoma Coptidis, Radix Glycyrrhizae, Zaocys, Periostracum Cicadae, Scorpio, Nidus Vespae are for making medicine, so medical material plays drug effect jointly according to the principle of monarch.

Antipsoriatics thing clearing away heat and cooling blood of the present invention, search wind antipruritic, moisturize yin nourishing, damp eliminating blood stasis dispelling, the psoriasis that effectively can treat blood hot air wind producing disease, wind syndrome due to blood-deficiency disease, ailment said due to cold or exposure accumulate melancholia etc. is caused.

Detailed description of the invention

Embodiment 1:

Take the Radix Astragali 30 grams, Rauvolfia verticillata 40 grams, Radix Saposhnikoviae 15 grams, Rhizoma Arisaematis 35 grams, Cortex Moutan 15 grams, Herba Taraxaci 30 grams, Cortex Phellodendri 15 grams, Rhizoma Atractylodis 15 grams, Nodus Nelumbinis Rhizomatis 35 grams, Herba Portulacae 30 grams, Radix Arnebiae (Radix Lithospermi) 20 grams, Rhizoma Coptidis 15 grams, Cortex Dictamni 20 grams, Cortex Lycii 20 grams, Radix et Rhizoma Smilacis Ripariae 40 grams, 15 grams, Radix Glycyrrhizae, Bombyx Batryticatus 20 grams, Radix Trichosanthis 20 grams, Radix Paeoniae Rubra 20 grams, the Rhizoma Anemarrhenae 20 grams, Caulis Spatholobi 20 grams, Fructus Cnidii 20 grams, the Fructus Kochiae 20 grams, Rhizoma Atractylodis Macrocephalae preparata 20 grams, Semen Coicis 30 grams, Herba Zornia Diphyllae 40 grams, Zaocys 15 grams, Periostracum Cicadae 15 grams, Scorpio 10 grams, 15 grams, Nidus Vespae, Carapax Et Plastrum Testudinis 25 grams and Carapax Trionycis 25 grams, add 60000 milliliters, water, heat 5 hours at 90 DEG C in the flask that condenser is housed, filter, filtrate is decoction of the present invention.

Experimental example

Select between in January, 2012 in December ,-2013, to diagnose medical patient 60 example to me, wherein man 30 example, female 30 example; Age reckling 26 years old, the maximum 55 years old; Stadium the shortest person January, most elder 2 years; Person 12 example that skin starts from extremity, head 16 example, facial person 3 example, trunk person 8 example, whole body person 10 example, buttocks person 11 example; Acute attack 21 example, chronic disease person 35 example, not clear person 4 example.After diagnosing, wherein erythroderma-type psoriatic 12 example, pustule-type psoriatic 11 example, acute psoriasis punctata patient 19 example of homeliness type, homeliness type chronic patch shape psoriatic 18 example.

The decoction of preparation in embodiment 1 is used to treat, every day 1 time, oral 100 milliliters at every turn, continuous 2 weeks.

The criterion of clinical therapeutic efficacy is:

Clinical cure: skin lesion disappears completely or only stays several unconspicuous point erythra.

Effective: erythra more than 90% disappears, and pruritus obviously alleviates.

Effective: between deflorescence 40%-90%, pruritus alleviates.

Invalid: deflorescence is not obvious or increase the weight of.

Through treatment, find in 60 routine patients, clinical cure 10 example, effective 32 examples, effective 18 examples, invalid 0 example.And over the course for the treatment of, do not find that the significantly untoward reaction such as Nausea and vomiting appear in patient.

Model case

Zhang, man, 38 years old, Dian Shang town, Lucheng City, Shanxi peasant.Because of heavy cold before 1 year, after hyperpyrexia, whole body general psoriasis, extremity, head, whole body have tinea.Going to a doctor in Duo Jia hospital uses hormone to treat, all invalid.In August, 2012, I diagnosed medical, used the decoction of preparation in embodiment 1 to treat, every day 1 time, oral 100 milliliters at every turn, continuous 2 weeks.Observe whole body and have no obvious tinea, also without the sensation of any pruritus, also without the obvious erythra of discovery.Going home normally to be engaged in agriculture, carrying out with examining 3 months subsequently every months, also do not find the sign recurred.

Hu, man, 52 years old, Taiyuan, Shanxi people, civil servant.Happen suddenly the Spring Festival in 2012 in the red macule of Head And Face, peel in a large number, accompany violent pruritus; Be diagnosed as psoriasis in specialist hospital, after the treatment of Western medicine hormones, the state of an illness does not take a turn for the better, and spreads to whole body, and extremity are in a bad way, and has a strong impact on work and life.Treat in December, 2012 is well-known to this clinic.The decoction of preparation in embodiment 1 is used to treat, every day 1 time, oral 100 milliliters at every turn, continuous 2 weeks.Observation General Symptoms disappears, without the sensation of any pruritus, also without the obvious erythra of discovery.Carrying out phone with examining 3 months subsequently every months, also not finding the sign recurred.

Liu so-and-so, female, 43 years old, urban district, Lucheng City, Shanxi textile female worker.Well-knownly to treat to this clinic in February, 2013.Patient suffers from erythroderma-type psoriasis, and state case history more than 1 year, never stopped treatment, various big hospital was all controlled, all invalid and return.All the time thoroughly do not cure.Patient does not have tinea except head, face, and shirtfront, back tinea are less, and extremity especially severe, summer, sky heat dare not expose extremity.The decoction of preparation in embodiment 1 is used to treat, every day 1 time, oral 100 milliliters at every turn, continuous 2 weeks.Observation General Symptoms disappears, without the sensation of any pruritus, also without the obvious tinea of discovery.Carrying out phone with examining 3 months subsequently every months, also not finding the sign recurred.

Poplar, female, 29 years old, Wei Zi people from town, Lucheng City, Shanxi, patient suffered from psoriasis a year and a half, goes to a doctor invalid in Duo Jia hospital, and the countless folk prescription prescription of rear use is not all cured, and treats in June, 2013 to this clinic.The decoction of preparation in embodiment 1 is used to treat, every day 1 time, oral 100 milliliters at every turn, continuous 2 weeks.Pruritus stops, and silver bits disappear.Carrying out phone with examining 3 months subsequently every months, also not finding the sign recurred.

Claims

1. an antipsoriatics thing, it is characterized in that, it is made up of the material of following weight proportioning: Radix Astragali 25-35 part, Rauvolfia verticillata 30-40 part, Radix Saposhnikoviae 10-20 part, Rhizoma Arisaematis 25-35 part, Cortex Moutan 10-20 part, Herba Taraxaci 26-31 part, Cortex Phellodendri 10-20 part, Rhizoma Atractylodis 10-20 part, Nodus Nelumbinis Rhizomatis 25-40 part, Herba Portulacae 25-35 part, Radix Arnebiae (Radix Lithospermi) 15-25 part, Rhizoma Coptidis 10-20 part, Cortex Dictamni 15-27 part, Cortex Lycii 15-27 part, Radix et Rhizoma Smilacis Ripariae 30-40 part, Radix Glycyrrhizae 10-20 part, Bombyx Batryticatus 15-25 part, Radix Trichosanthis 15-25 part, Radix Paeoniae Rubra 15-25 part, Rhizoma Anemarrhenae 15-25 part, Caulis Spatholobi 15-25 part, Fructus Cnidii 15-25 part, Fructus Kochiae 15-25 part, Rhizoma Atractylodis Macrocephalae preparata 15-25 part, Semen Coicis 25-35 part, Herba Zornia Diphyllae 30-40 part, Zaocys 10-20 part, Periostracum Cicadae 10-20 part, Scorpio 5-15 part, Nidus Vespae 10-20 part, Carapax Et Plastrum Testudinis 25-35 part and Carapax Trionycis 25-35 part.

2. antipsoriatics thing according to claim 1, it is characterized in that, it is made up of the material of following weight proportioning: the Radix Astragali 30 parts, Rauvolfia verticillata 40 parts, Radix Saposhnikoviae 15 parts, Rhizoma Arisaematis 35 parts, Cortex Moutan 15 parts, Herba Taraxaci 30 parts, Cortex Phellodendri 15 parts, Rhizoma Atractylodis 15 parts, Nodus Nelumbinis Rhizomatis 35 parts, Herba Portulacae 30 parts, Radix Arnebiae (Radix Lithospermi) 20 parts, Rhizoma Coptidis 15 parts, Cortex Dictamni 20 parts, Cortex Lycii 20 parts, Radix et Rhizoma Smilacis Ripariae 40 parts, 15 parts, Radix Glycyrrhizae, Bombyx Batryticatus 20 parts, Radix Trichosanthis 20 parts, Radix Paeoniae Rubra 20 parts, the Rhizoma Anemarrhenae 20 parts, Caulis Spatholobi 20 parts, Fructus Cnidii 20 parts, the Fructus Kochiae 20 parts, Rhizoma Atractylodis Macrocephalae preparata 20 parts, Semen Coicis 30 parts, Herba Zornia Diphyllae 40 parts, Zaocys 15 parts, Periostracum Cicadae 15 parts, Scorpio 10 parts, 15 parts, Nidus Vespae, Carapax Et Plastrum Testudinis 25 parts and Carapax Trionycis 25 parts.