CN101375955B - Sperm-passing formulation for treating non-ejaculation symptom and preparation method thereof - Google Patents
Sperm-passing formulation for treating non-ejaculation symptom and preparation method thereof Download PDFInfo
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- CN101375955B CN101375955B CN2008101519138A CN200810151913A CN101375955B CN 101375955 B CN101375955 B CN 101375955B CN 2008101519138 A CN2008101519138 A CN 2008101519138A CN 200810151913 A CN200810151913 A CN 200810151913A CN 101375955 B CN101375955 B CN 101375955B
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Abstract
The invention discloses an ejaculation unchoking preparation for treating ejaculatory incompetence and the preparation method thereof. The ejaculation unchoking preparation is prepared from the following medicament raw materials with proportions by weight: 300-600 parts of seed of garden balsam, 350-450 parts of fructus liquidambaris, 3-5 parts of chilopod, 360-510 parts of radix salviae miltiorrhizae, 180-260 parts of red paeonia, 30-60 parts of Chinese date, 200-450 parts of radix bupleuri and 80-130 parts of radix achyranthis bidentatae. The ejaculation unchoking preparation for treating the ejaculatory incompetence extracts the effective ingredients in the medicament raw materials by using a water cooking and extraction method and keeps the activity of the effective ingredients. Therefore, not only the dissolution rate of the effective ingredients in the medicament is improved greatly, but also the medicament is absorbed effectively, thereby improving the bioavailability. In addition, the medicine of the invention is a pure traditional Chinese medicine preparation, so that no toxic and side effects are existent after a patient uses for a long time, and the preparation has goodsafety. Moreover, the preparation method has the advantages of simple process and convenient operation.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation and preparation method thereof, particularly relate to a kind of with Chinese medicine be raw material make be used for the treatment of logical finishing agent of anejaculation and preparation method thereof.
Background technology
Medically penis can normal erection in the sexual intercourse process with the man, and sexual intercourse can continue the enough time, but can not be called anejaculation in the disease that intravaginal is ejaculated.Though the types of drugs that is used for the treatment of at present anejaculation clinically very little, and specific aim is not strong, and the toxic and side effects of some medicine is big, so take back DeGrain for this disease of treatment anejaculation.
Summary of the invention
In order to address the above problem, the object of the present invention is to provide a kind of treatment anejaculation effect obvious, thereby with strong points, and the logical finishing agent that is used for the treatment of anejaculation that has no side effect.
Another object of the present invention is to provide a kind of method that is used to prepare above-mentioned logical finishing agent.
In order to achieve the above object, the logical finishing agent that is used for the treatment of anejaculation provided by the invention is that the following medicine material of weight ratio is made by consumption mainly:
Semen Impatientis 300-600 Fructus Liquidambaris 350-450 Scolopendras 3-5
Radix Salviae Miltiorrhizae 360-510 Radix Paeoniae Rubra 180-260 Fructus Jujubaes 30-60
Radix Bupleuri 200-450 Radix Achyranthis Bidentataes 80-130
The described preparation method that is used for the treatment of the logical finishing agent of anejaculation is to carry out according to the following step order:
(a) the said medicine raw material is carried out weighing and mix homogeneously according to proportioning, decoct with water then 2 times, each 2 hours, merging filtrate filtered, and is concentrated into thick paste;
(b) with above-mentioned thick paste according to the pharmaceutical technology of routine and add corresponding common medicinal supplementary material and make oral solid formulation, oral liquid.
The logical finishing agent that is used for the treatment of anejaculation provided by the invention is that the method for employing decocting in water extraction is extracted the effective ingredient in the material medicine, and keep its activity, can make so not only that the dissolution of effective ingredient improves greatly in the medicine, and help the absorption of medicine, thereby can improve its bioavailability.In addition, medicine of the present invention is a pure Chinese medicinal preparation, thereby the patient can not produce toxic and side effects after taking for a long time, so safety is good.In addition, preparation method technology of the present invention is simple, easy to operate.
The specific embodiment
This side is set for the treatment anejaculation.Semen Impatientis toil temperature in the side, removing blood stasis removing food stagnancy, softening the hard mass pain relieving; Fructus Liquidambaris is arduous flat, and collateral dredging dispels the wind, the diuretic dehumidifying; The salty temperature of Scolopendra, activating collaterals and eliminating stagnation, three medicines share, and the power of collateral dredging is stronger, is to be monarch drug.The Radix Salviae Miltiorrhizae hardship is slightly cold, nourshing blood and promoting blood circulation, disease eliminating powder junction; The Radix Paeoniae Rubra hardship is slightly cold, clearing away heat and cooling blood, and promoting blood circulation to remove blood stasis is ministerial drug altogether.The Radix Bupleuri suffering is slightly cold, but both soothing liver-QI for relieving depression, but ascending up spleen-Qi and Yang again; Fructus Jujubae is sweet flat, invigorating the spleen and replenishing QI, and the effect of tool nourishing blood to tranquillize the mind, and the same usefulness of two medicines, but the liver soothing and the spleen invigorating is an adjuvant drug.The Radix Achyranthis Bidentatae suffering is slightly cold, blood circulation promoting and blood stasis dispelling, and priming is descending, thinks messenger drug.Full side's medication is with promoting blood circulation to remove obstruction in the collateral, and dispersing the stagnated live-QI to relieve the stagnation of QI is an aim, looses in order to do the stagnation resolvation knot, and penis must relax, then the orifice for discharging seminal fluid diarrhea.
Below in conjunction with embodiment logical finishing agent that is used for the treatment of anejaculation provided by the invention and preparation method thereof is elaborated.
Embodiment 1:
The logical finishing agent that is used for the treatment of anejaculation in the present embodiment is that the following medicine material of weight ratio is made by consumption mainly:
Semen Impatientis 500 Fructus Liquidambaris 400 Scolopendras 4
Radix Salviae Miltiorrhizae 400 Radix Paeoniae Rubra 200 Fructus Jujubaes 55
Radix Bupleuri 300 Radix Achyranthis Bidentataes 100
Preparation method:
(a) the said medicine raw material is carried out weighing and mix homogeneously according to proportioning, decoct with water then 2 times, each 2 hours, merging filtrate filtered, and is concentrated into thick paste;
(b) with above-mentioned thick paste according to the pharmaceutical technology of routine and add corresponding common medicinal supplementary material and make oral solid formulation, oral liquid.
Embodiment 2:
The logical finishing agent that is used for the treatment of anejaculation in the present embodiment is that the following medicine material of weight ratio is made by consumption mainly:
Semen Impatientis 300 Fructus Liquidambaris 350 Scolopendras 3
Radix Salviae Miltiorrhizae 360 Radix Paeoniae Rubra 180 Fructus Jujubaes 30
Radix Bupleuri 200 Radix Achyranthis Bidentataes 80
Preparation method is with embodiment 1.
Embodiment 3:
The logical finishing agent that is used for the treatment of anejaculation in the present embodiment is that the following medicine material of weight ratio is made by consumption mainly:
Semen Impatientis 600 Fructus Liquidambaris 450 Scolopendras 5
Radix Salviae Miltiorrhizae 510 Radix Paeoniae Rubra 260 Fructus Jujubaes 60
Radix Bupleuri 450 Radix Achyranthis Bidentataes 130
Preparation method is with embodiment 1.
The logical finishing agent that is used for the treatment of anejaculation provided by the invention is brown to sepia, and it is little sweet to distinguish the flavor of.In order to verify the therapeutic effect of this logical finishing agent, the patient that the inventor utilizes the capsule that belongs to oral administration solid system in the above-mentioned logical finishing agent that 232 examples are suffered from anejaculation has carried out system's clinical observation, 21-30 year patient's 57 examples wherein, 31-40 year patient's 74 examples, 41-50 year patient's 101 examples, 3 of each medications, every day 2 times, 60 days is 1 course of treatment.After 1 course of therapy, cure (the same branch of a family can be finished ejaculation) 21 examples altogether, account for 9.1%; Effectively (have sexual intercourse and still can not finish ejaculation, other symptom has significant change) 124 examples account for 53.4%; Invalid (have sexual intercourse and still can not finish ejaculation, other symptom does not have significant change) 87 examples account for 37.5%; Total effective rate is 62.5%.After 2 course of therapy, cure 65 examples altogether, account for 28.0%; Effective 79 examples account for 34.1%; Invalid 58 examples account for 25.0%; Total effective rate is 75.0%.
Simultaneously, the inventor analyzes therapeutic effect and age, therapeutic effect and the relation between the course of treatment, and analysis result sees Table 1 respectively, table 2.
Table 1: logical finishing agent therapeutic effect provided by the invention and age relation table
With the data x in the above-mentioned table 1
2Method of inspection calculates, and the result is 0.050〉P〉0.025, can prove that thus taking logical finishing agent provided by the invention treats anejaculation, and the therapeutic effect of each age group is not changed with the age.
Table 2: logical finishing agent therapeutic effect provided by the invention and the course of treatment relation table
With the data x in the above-mentioned table 2
2Method of inspection calculates, and the result is P＜0.005, can prove that thus taking logical finishing agent provided by the invention treats anejaculation, and along with going deep into of treatment, cure rate, effective percentage all obviously improve.
Claims (2)
1. logical finishing agent that is used for the treatment of anejaculation is characterized in that: the described logical finishing agent that is used for the treatment of anejaculation is that the following medicine material of weight ratio is made by consumption:
Semen Impatientis 300-600 Fructus Liquidambaris 350-450 Scolopendra 3-5
Radix Salviae Miltiorrhizae 360-510 Radix Paeoniae Rubra 180-260 Fructus Jujubae 30-60
Radix Bupleuri 200-450 Radix Achyranthis Bidentatae 80-130.
2. preparation method that is used for the treatment of the logical finishing agent of anejaculation as claimed in claim 1, it is characterized in that: the described preparation method that is used for the treatment of the logical finishing agent of anejaculation is to carry out according to the following step order:
(a) the said medicine raw material is carried out weighing and mix homogeneously according to proportioning, decoct with water then 2 times, each 2 hours, merging filtrate filtered, and is concentrated into thick paste;
(b) with above-mentioned thick paste according to the pharmaceutical technology of routine and add corresponding common medicinal supplementary material and make oral solid formulation or oral liquid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008101519138A CN101375955B (en) | 2008-09-27 | 2008-09-27 | Sperm-passing formulation for treating non-ejaculation symptom and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008101519138A CN101375955B (en) | 2008-09-27 | 2008-09-27 | Sperm-passing formulation for treating non-ejaculation symptom and preparation method thereof |
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| Publication Number | Publication Date |
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| CN101375955A CN101375955A (en) | 2009-03-04 |
| CN101375955B true CN101375955B (en) | 2011-08-24 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2008101519138A Expired - Fee Related CN101375955B (en) | 2008-09-27 | 2008-09-27 | Sperm-passing formulation for treating non-ejaculation symptom and preparation method thereof |
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Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102688446B (en) * | 2012-05-08 | 2014-04-09 | 安徽智远生物科技有限公司 | Traditional Chinese medicine for treating male infertility and preparation method thereof |
| CN103202893A (en) * | 2013-04-16 | 2013-07-17 | 上海浦东高星生物技术研究所 | Tongjing tablets |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101066360A (en) * | 2007-06-05 | 2007-11-07 | 北京艺信堂医药研究所 | Chinese medicine for treating sterility of emission absence |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101066360A (en) * | 2007-06-05 | 2007-11-07 | 北京艺信堂医药研究所 | Chinese medicine for treating sterility of emission absence |
Non-Patent Citations (1)
| Title |
|---|
| 周贤道.排精汤加针刺治疗不射精症30例.《新中医》.1993,第25卷(第8期),38. * |
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Effective date of registration: 20170606 Address after: 300210 Tianjin city Hexi District Liberation Road No. 447 Patentee after: Tianjin Caokaiyong Hospital of traditional Chinese Medicine Address before: Yingkou Heping District 300040 Tianjin City Road 36 No. E119 Patentee before: Cao Kaiyong |
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