CN101496892B - Oral Chinese patent medicine for treating cardiovascular disease - Google Patents
Oral Chinese patent medicine for treating cardiovascular disease Download PDFInfo
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- CN101496892B CN101496892B CN2008101905937A CN200810190593A CN101496892B CN 101496892 B CN101496892 B CN 101496892B CN 2008101905937 A CN2008101905937 A CN 2008101905937A CN 200810190593 A CN200810190593 A CN 200810190593A CN 101496892 B CN101496892 B CN 101496892B
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Abstract
The invention provides an orally-administrated Chinese patent medicine for treating cardiovascular and cerebrovascular diseases, which consists of the following Chinese herbal medicines according to certain weight ratio: bulbus allii macrostemi, dwarf lilyturf root, shizandra berry, balloon flower, hairy holly root, radix salviae miltiorrhizae, woodlouse, radix paeoniae rubra, rhizoma ligustici wallichii, red sandalwood, leech, cornus officinalis sieb et zucc, morinda root fruit, himalayan teasel root, parasite scurrula, eucommia bark carbon, tuckahoe, rhizoma alismatis, armand clematis, polygala, shelled cedar seed, radix bupleuri, cortex magnoliae officinalis, rhizoma corydalis, herba asaricum radice, zoacys dhumnades, radix geutianae, scutellaria barbata, radix trichosanthis, bugleweed, uncaria, sea-ear shell, magnet, radix linderae and zedoary. The orally-administrated Chinese patent medicine has the efficacies of nourishing the kidney yin, invigorating the kidney yang, regulating recuperative cardiac function, promoting blood circulation, dispelling blood-arthralgia, promoting blood circulation and removing blood stasis, eliminating the pathogenic factors and freeing the collateral vessels, and the curative effectiveness rate to the cardiovascular and cerebrovascular diseases reaches more than 96 percent.
Description
Technical field
The invention belongs to field of traditional Chinese, providing a kind of is the oral Chinese patent medicine of the treatment cardiovascular and cerebrovascular disease of feedstock production with the Chinese herbal medicine.
Background of invention
Cardiovascular and cerebrovascular disease mainly comprises diseases such as hypertension, coronary atherosclerotic heart disease, cerebral ischemia, cerebral thrombosis, belongs to commonly encountered diseases, frequently-occurring disease, serious threat human beings'health and daily life.
The cardiovascular and cerebrovascular disease complex genesis.Hypertension is relevant with factors such as secular psychentonia, the exercise of shortage body, overweight, heredity, excess salt and smokings, and the pathogeny theory is more, it is generally acknowledged that renin angiotensin aldosterone system and hypertension incidence are closely related.At present clinical these treatment of diseases means are comprised blood pressure lowering, expand blood vessel, activating blood circulation to dissipate blood stasis, dispel the wind etc.The weak point that exists is: 1) to hypertensive treatment based on Western medicine, most depressor can only play the effect of temporary transient blood pressure lowering, and serious rebound phenomenon is arranged; 2) therapeutic modality to arteriosclerotic disease (as coronary heart disease, cerebrovascular sclerosis disease etc.) all is to carry out symptomatic treatment by modes such as heart tonifying, expansion blood vessels, and the performance respite act as the master; 3) most preparations scope of suiting the medicine to the illness is narrow, lacks combined therapy effect; 4) single disease is singly controlled, and does not consider other factors.
The traditional Chinese medical science has its unique distinction to the treatment of cardiovascular and cerebrovascular disease.As, the Bulbus Allii Macrostemonis the chest stuffiness relieving of regulating the flow of vital energy, but Radix Ophiopogonis nourishing YIN and moistening the lung, the relieving restlessness that clears away heart-fire, and Fructus Schisandrae Chinensis then can nourishing kidney, astringe the lung and promote the production of body fluid.Three flavor medicines, 5, one benefits one clear are mutually held back, and all can promote the production of body fluid, and the multiple Tianjin of gas is returned, and the gas sun fills in sering, at the other medicines blood circulation promoting and blood stasis dispelling, makes blood circulation normal, its arteries and veins demutation, and heart is normal.Therefore use Chinese medicinal formulae to treat this type of disease wide development space is arranged.
Summary of the invention
Purpose of the present invention is intended to overcome above-mentioned shortcoming, and the Chinese patent medicine of the treatment cardiovascular disease that a kind of curative effect is fast, effect is lasting, have no side effect is provided.For reaching above-mentioned purpose, solution of the present invention is to pathogenetic understanding of cardiovascular and cerebrovascular disease and Therapeutic Principle according to the traditional Chinese medical science, with reference to the modern pharmacological research result, and clinical practice for many years, from motherland's medical treasure-house screening side fill blood, nourishing kidney-yin kidney-replenishing, promoting blood circulation, by the natural Chinese medicinal herb of arthralgia due to stagnation of blood, blood circulation promoting and blood stasis dispelling, eliminating evil collateral dredging, theoretical by traditional Chinese medical science prescription, make oral Chinese patent medicine.
The inventor thinks that the cause of disease of cardiovascular disease is: heart disease is many by the deficiency of vital energy, blood deficiency, caused by energy stagnation and blood stasis.Later stage hypertension causes cerebral arteries to break, the sequela that stays after rescuing, hemiplegia, aphasis etc.The cause of disease of cerebral thrombosis and embolus mainly from various heart diseases, easily play coming off of wall thrombosis and wait all thrombosis to come off, and enter entocranial artery blood, all can invite to cause cerebral thrombosis.Cardiovascular and cerebrovascular disease often shows as the painstaking effort stasis of blood, heart infarction, arrhythmia, the rhythm of the heart is slow, blood pressure is higher, and often low pressure, high pressure remain high.The heart infarction painstaking effort stasis of blood needs blood circulation promoting and blood stasis dispelling, and blood pressure is higher to need blood pressure lowering, uses drug for invigorating blood circulation and eliminating stasis, and blood pressure raises again, invigorates blood circulation and the two mutual contradiction of blood pressure lowering.With Western medicine can't the treatment situation under, with herbal raw material make Chinese patent medicine, pill is expected to overcome the above-mentioned Western medicine deficiency of using.
At the rhythm of the heart slowly, heart blood supply insufficiency, myocardial ischemia, sensation of oppression over the chest with shortness of breath, back and waist all pain, abdominal distention insomnia, up and down obstructed, be hard and dry, anasarca, available Bulbus Allii Macrostemonis, Radix Ophiopogonis, Fructus Schisandrae Chinensis, Radix Platycodonis, Mao Dongqing, Fructus Corni, Radix Morindae Officinalis, material Hu, Herba Asari, Zaocys, half piece of Chinese medicine such as lotus, " the logical gate of vitality; warm public region " soothing liver-QI is sensible, actuator energy water channel, Liver and kidney is normal, and above-mentioned various diseases everyday disappears.
Based on above-mentioned consideration, the inventor consults amount of literature data and clinical practice for many years, determine " gas of enriching blood, promoting blood circulation, by arthralgia due to stagnation of blood, blood circulation promoting and blood stasis dispelling, eliminating evil collateral dredging " be the principles of formulating prescriptions.Bulbus Allii Macrostemonis is regulated the flow of vital energy in the prescription of the present invention, the chest stuffiness relieving, and the thoracic obstruction is had a pain; The clear and rich lung of Radix Ophiopogonis, relieving cough and resolving phlegm, nourishing the stomach to promote the production of body fluid; The Fructus Schisandrae Chinensis nourishing kidney, astringe the lung promote the production of body fluid, the deficiency of the lung is breathed with cough, the cough-relieving of Radix Platycodonis lung qi dispersing, eliminate the phlegm; Radix Ilicis Pubescentis, blood circulation and channel invigorating, reducing swelling and alleviating pain, Radix Salviae Miltiorrhizae activating blood circulation and dissipating phlegm, calming heart and tranquilizing mind; Eupolyphage sece steleophaga, removing blood stasis with potent drugs blood, stomachache; Radix Paeoniae Rubra removing fire from the liver, activating blood circulation and dissipating phlegm; Rhizoma Chuanxiong, congestion invigorating the liver and kidney, pain relieving disappear; Lignum pterocarpi indici regulating qi-flowing for harmonizing stomach, trusted subordinate's pain; The Hirudo removing blood stasis; Fructus Corni invigorating the liver and kidney, warm waist controlling nocturnal emission with astringent drugs; The bone and muscle strengthening of Radix Morindae Officinalis kidney-replenishing; Parasitic wind-damp dispelling, invigorating the liver and kidney, antiabortive; The Radix Dipsaci invigorating the liver and kidney; The charred Cortex Eucommiae invigorating the liver and kidney, strengthening bone and muscle, blood pressure lowering; The Poria inducing diuresis to remove edema; Herba Euphorbiae Helioscopiae eliminating dampness by diuresis diarrhea of heat type urine; The Caulis Clematidis Armandii clearing away heart-fire, rush down damp and hot, the diuretic lactogenesis; The Radix Polygalae intelligence promoting and the mind tranquilizing; Semen Platycladi tranquilizing by nourishing the heart loosening bowel to relieve constipation; Material is separated the exterior and the interior recklessly, soothing the liver yang invigorating; The Cortex Magnoliae Officinalis intestinal stasis relieving therapeutic method to keep the adverse QI flowing downwards is removed full; The Rhizoma Corydalis removing blood stasis and activating blood flow, promoting the circulation of QI to relieve pain; The Herba Asari wind cold relieving of loosing, sensible analgesia; Zaocys wind-damp dispelling, pain relieving, arresting convulsion; The cursive liver and gall excess-fire of Radix Gentianae, remove the damp-heat in lower-JIAO appetizing; Herba Scutellariae Barbatae, heat-clearing and toxic substances removing, inducing diuresis to remove edema; The pollen promoting the production of body fluid to quench thirst, will obtain moisturize, evacuation of pus detumescence; Spica Prunellae clearing away liver-fire, Disperse hepatic depression; Ramulus Uncariae Cum Uncis heat clearing away suppressing the hyperactive liver, dispelling wind and relieving convulsion, blood pressure lowering; The Concha Haliotidis suppressing the hyperactive liver is for sun, removing nebula to improve visual acuity; Radix Linderae warming middle-JIAO is pleasant, relieving dyspepsia; Rhizoma Wenyujin Concisum, circulation of qi promoting removing blood stasis with potent drugs, the blood stasis dispelling of eliminating the phlegm; Magnetitum, suppressing the hyperactive liver is for sun, tranquilizing mind.
According to above thinking, Chinese patent medicine of the present invention is made by the Chinese patent medicine raw material of following weight proportion:
Bulbus Allii Macrostemonis 10-40 part Radix Ophiopogonis 10-45 part Fructus Schisandrae Chinensis 10-40 part straw stalk 10-40 part
Radix Ilicis Pubescentis 20-40 part Radix Salviae Miltiorrhizae 15-35 part eupolyphage sece steleophaga 5-25 part Radix Paeoniae Rubra 10-30 part
Rhizoma Chuanxiong 15-35 part Lignum pterocarpi indici 10-30 part Hirudo 1-15 part Fructus Corni 15-35 part
Radix Morindae Officinalis 15-35 part Radix Dipsaci 15-30 part Herba Taxilli 15-35 part charred Cortex Eucommiae 10-35 part
Poria 10-25 part Herba Euphorbiae Helioscopiae 10-20 part Caulis Clematidis Armandii 10-30 part Radix Polygalae 15-35 part
Semen Platycladi 15-35 part material is 15-35 part Cortex Magnoliae Officinalis 10-30 part Rhizoma Corydalis 15-35 part recklessly
Herba Asari 5-15 part Zaocys 10-30 part Radix Gentianae 10-30 part Herba Scutellariae Barbatae 20-40 part
Radix Trichosanthis 20-30 part Spica Prunellae 10-30 part Ramulus Uncariae Cum Uncis 10-30 part Concha Haliotidis 20-40 part
Magnetitum 10-30 part Radix Linderae 10-30 part Rhizoma Wenyujin Concisum 15-35 part
The optimum weight proportioning of the various raw materials of Chinese patent medicine of the present invention is:
30 parts on 30 parts of straw stalks of 35 parts of Fructus Schisandrae Chinensis of 30 parts of Radix Ophiopogonis of Bulbus Allii Macrostemonis
25 parts of 20 parts of Radix Paeoniae Rubra of 30 parts of eupolyphage sece steleophagas of 30 parts of Radix Salviae Miltiorrhizaes of Radix Ilicis Pubescentis
30 parts of 10 parts of Fructus Corni of 25 portions of Hirudos of 30 parts of Lignum pterocarpi indici of Rhizoma Chuanxiong
30 parts of 30 parts of charred Cortex Eucommiaes of 25 parts of Herba Taxillis of 30 parts of Radix Dipsaci of Radix Morindae Officinalis
30 parts of 25 parts of Radix Polygalaes of 15 portions of Caulis Clematidis Armandiis of 20 parts of Herba Euphorbiae Helioscopiae of Poria
30 parts of 25 parts of Rhizoma Corydalis of 30 parts of materials 30 parts of Cortex Magnoliae Officinalis of Hu of Semen Platycladi
30 parts of 25 portions of Herba Scutellariae Barbataes of 25 portions of Radix Gentianaes of 10 parts of Zaocys of Herba Asari
30 parts of 25 parts of Concha Haliotidis of 25 parts of Ramulus Uncariae Cum Uncis of 25 parts of Spica Prunellaes of Radix Trichosanthis
30 parts of 25 parts of Rhizoma Wenyujin Concisum of 25 parts of Radixs Linderae of Magnetitum
The herbal raw material of above-mentioned weight proportion is ground into granule, adds pharmaceutic adjuvant acceptable such as Mel, make oral Chinese patent medicine.
Above-mentioned 30 five kinds of Chinese medicine are worked in coordination, and play jointly: fill blood, promoting blood circulation, nourishing kidney tonifying YANG, by the effect of arthralgia due to stagnation of blood, blood circulation promoting and blood stasis dispelling, eliminating evil collateral dredging, meet the traditional Chinese medical science to pathogenetic understanding of cardiovascular and cerebrovascular disease and Therapeutic Principle.
For showing therapeutic effect of the present invention, with the clinical efficacy situation of Chinese patent drugs for treatment 100 routine various cardiovascular and cerebrovascular diseases of the present invention.Add up as follows:
One. case is selected:
Two. Therapeutic Method:
To being diagnosed as the cardiovascular and cerebrovascular disease patient, give Chinese patent medicine of the present invention and take, seriously ill person every day three times, the sick the lighter of each ball (9 gram) every day twice, each ball (9 gram) was a course of treatment in per 30 days, took three courses of treatment continuously.
Three. the treatment standard
Produce effects: clinical symptom disappearance, functional rehabilitation is normal.Drug withdrawal was not seen the recidivist more than 1 year.
Effectively: clinical symptom relief, the state of an illness recover stable, observe more than one month.
Invalid: clinical symptoms does not have obvious improvement.
Four. the curative effect statistics:
| Disease | Case load | Produce effects | Effectively | Invalid | Effective percentage |
| Hypertension | 30 | ?20 | ?9 | ?/ | ?96％ |
| Heart disease | 40 | ?30 | ?8 | ?2 | ?95％ |
| Cerebral thrombosis | 30 | ?20 | ?8 | ?2 | ?95％ |
By above-mentioned clinical data as seen, Chinese patent medicine of the present invention all has good curative effect to the cardiovascular and cerebrovascular disease of the various rational faculties, and the treating both the principal and secondary aspects of a disease effective percentage reaches 96%.
The present invention has following advantage:
The present invention selects pure Chinese herbal medicine to be raw material, and is nontoxic to human body, has no side effect.
The present invention need not to decoct, and treatment is convenient, and effective percentage reaches 96%.
Prescription of the present invention meets the traditional Chinese medical science to pathogenetic understanding of cardiovascular and cerebrovascular disease and Therapeutic Principle, and clothes can reach the purpose that blood stasis dispelling is kept fit for a long time.
For the preparation of pharmaceutical preparation of the present invention is described better, be exemplified below.
Embodiment 1
Accurately take by weighing following raw materials according:
Bulbus Allii Macrostemonis 30g Radix Ophiopogonis 35g Fructus Schisandrae Chinensis 30g straw stalk 30g
Radix Ilicis Pubescentis 30g Radix Salviae Miltiorrhizae 30g eupolyphage sece steleophaga 20g Radix Paeoniae Rubra 25g
Rhizoma Chuanxiong 30g Lignum pterocarpi indici 25g Hirudo 10g Fructus Corni 30g
Radix Morindae Officinalis 30g Radix Dipsaci 25g Herba Taxilli 30g charred Cortex Eucommiae 30g
Poria 20g Herba Euphorbiae Helioscopiae 15g Caulis Clematidis Armandii 25g Radix Polygalae 30g
Semen Platycladi 30g material is 30g Cortex Magnoliae Officinalis 25g Rhizoma Corydalis 30g recklessly
Herba Asari 10g Zaocys 25g Radix Gentianae 25g Herba Scutellariae Barbatae 30g
Radix Trichosanthis 25g Spica Prunellae 25g Ramulus Uncariae Cum Uncis 25g Concha Haliotidis 30g
Magnetitum 25g Radix Linderae 25g Rhizoma Wenyujin Concisum 30g
Pulverizer is crushed to 80 orders, mixing; It is an amount of to add Mel, is prepared into the honeyed pill that unit dose is 9g.
Chinese herbal medicine need select only, choose impurity, heat dry after, be crushed to 80 orders with pulverizer, be mixed, Mel is heated about 100 degree, the aqueous vapor evaporation makes Mel pure, it is an amount of to add Mel, is prepared into the honeyed pill of unit dose 9 grams.
Claims (5)
1. a Chinese patent medicine oral formulations that is used for the treatment of cardiovascular and cerebrovascular disease is characterized in that, it is made up of according to certain weight ratio following each Chinese herbal medicine:
Bulbus Allii Macrostemonis 10-40 part Radix Ophiopogonis 10-45 part Fructus Schisandrae Chinensis 10-40 part Radix Platycodonis 10-40 part
Radix Ilicis Pubescentis 20-40 part Radix Salviae Miltiorrhizae 15-35 part eupolyphage sece steleophaga 5-25 part Radix Paeoniae Rubra 10-30 part
Rhizoma Chuanxiong 15-35 part Lignum pterocarpi indici 10-30 part Hirudo 1-15 part Fructus Corni 15-35 part
Radix Morindae Officinalis 15-35 part Radix Dipsaci 15-30 part Herba Taxilli 15-35 part charred Cortex Eucommiae 10-35 part
Poria 10-25 part Herba Euphorbiae Helioscopiae 10-20 part Caulis Clematidis Armandii 10-30 part Radix Polygalae 15-35 part
Semen Platycladi 15-35 part Radix Bupleuri 15-35 part Cortex Magnoliae Officinalis 10-30 part Rhizoma Corydalis 15-35 part
Herba Asari 5-15 part Zaocys 10-30 part Radix Gentianae 10-30 part Herba Scutellariae Barbatae 20-40 part
Radix Trichosanthis 20-30 part Spica Prunellae 10-30 part Ramulus Uncariae Cum Uncis 10-30 part Concha Haliotidis 20-40 part
Magnetitum 10-30 part Radix Linderae 10-30 part Rhizoma Wenyujin Concisum 15-35 part.
2. preparation according to claim 1, its weight proportion is:
30 parts of 30 parts of Radix Platycodoniss of 35 parts of Fructus Schisandrae Chinensis of 30 parts of Radix Ophiopogonis of Bulbus Allii Macrostemonis
25 parts of 20 parts of Radix Paeoniae Rubra of 30 parts of eupolyphage sece steleophagas of 30 parts of Radix Salviae Miltiorrhizaes of Radix Ilicis Pubescentis
30 parts of 10 parts of Fructus Corni of 25 portions of Hirudos of 30 parts of Lignum pterocarpi indici of Rhizoma Chuanxiong
30 parts of 30 parts of charred Cortex Eucommiaes of 25 parts of Herba Taxillis of 30 parts of Radix Dipsaci of Radix Morindae Officinalis
30 parts of 25 parts of Radix Polygalaes of 15 portions of Caulis Clematidis Armandiis of 20 parts of Herba Euphorbiae Helioscopiae of Poria
30 parts of 25 parts of Rhizoma Corydalis of 30 parts of Cortex Magnoliae Officinalis of 30 parts of Radix Bupleuri of Semen Platycladi
30 parts of 25 portions of Herba Scutellariae Barbataes of 25 portions of Radix Gentianaes of 10 parts of Zaocys of Herba Asari
30 parts of 25 parts of Concha Haliotidis of 25 parts of Ramulus Uncariae Cum Uncis of 25 parts of Spica Prunellaes of Radix Trichosanthis
30 parts of 25 parts of Rhizoma Wenyujin Concisum of 25 parts of Radixs Linderae of Magnetitum.
3. preparation according to claim 2 is characterized in that it is a peroral dosage form.
4. method for preparing the described preparation of claim 1-3, its key step comprises:
(1) the preparation needed raw material is crushed to more than fineness 20 orders, and mixing;
(2) add proper honey or other pharmaceutic adjuvant acceptable, be prepared into the honeyed pill of different size.
5. the described preparation of claim 1-3 is used for the treatment of application in the medicine of cardiovascular and cerebrovascular disease in preparation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008101905937A CN101496892B (en) | 2008-12-24 | 2008-12-24 | Oral Chinese patent medicine for treating cardiovascular disease |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2008101905937A CN101496892B (en) | 2008-12-24 | 2008-12-24 | Oral Chinese patent medicine for treating cardiovascular disease |
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| CN101496892B true CN101496892B (en) | 2011-05-04 |
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102091291B (en) * | 2010-12-06 | 2012-05-09 | 李新焕 | Chinese medicine composition for treating cerebral arteriosclerosis |
| CN102302741B (en) * | 2011-09-11 | 2012-11-07 | 齐玉霞 | Method for preparing traditional Chinese medicine (TCM) for treating heart blood stagnation type chest stuffiness |
| CN103800675A (en) * | 2014-03-10 | 2014-05-21 | 上海理工大学 | Traditional Chinese medicine for treating hypertension and preparation method of traditional Chinese medicine |
| CN104398087A (en) * | 2014-12-24 | 2015-03-11 | 黄俊柳 | Medical pillow for treating cerebral arteriosclerosis |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1352959A (en) * | 2000-11-02 | 2002-06-12 | 戚嘉和 | Chinese medicine for treating heart disease |
| CN1958034A (en) * | 2006-12-04 | 2007-05-09 | 杨梅青 | Medication for treating cardiovascular disease |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1352959A (en) * | 2000-11-02 | 2002-06-12 | 戚嘉和 | Chinese medicine for treating heart disease |
| CN1958034A (en) * | 2006-12-04 | 2007-05-09 | 杨梅青 | Medication for treating cardiovascular disease |
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