CN105535694A - Traditional Chinese medicine composition for treating hyperuricemia - Google Patents
Traditional Chinese medicine composition for treating hyperuricemia Download PDFInfo
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- CN105535694A CN105535694A CN201610107101.8A CN201610107101A CN105535694A CN 105535694 A CN105535694 A CN 105535694A CN 201610107101 A CN201610107101 A CN 201610107101A CN 105535694 A CN105535694 A CN 105535694A
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Abstract
The invention provides a traditional Chinese medicine composition for treating hyperuricemia. The traditional Chinese medicine composition for treating the hyperuricemia is prepared from, by weight, 15-25 parts of glabrous greenbrier rhizomes, 10-20 parts of yam rhizomes, 10-20 parts of semen coicis, 5-15 parts of radix astragali, 5-15 parts of motherworts, 5-15 parts of herba lysimachiae, 3-7 parts of semen plantaginis, 3-7 parts of salvia miltiorrhiza, 2-8 parts of Chinese rhubarb and 2-8 parts of licorice roots. The traditional Chinese medicine composition uses the pure natural medicinal materials which are wide in source, low in cost, free of toxic and side effects and reasonable in formula, produce the good synergic effect in curative effect and jointly achieve the good swell-eliminating, analgesic, anti-inflammatory and dampness-removing effects. The traditional Chinese medicine composition has the advantages of being fast in effect and high in cure rate, enabling the hyperuricemia not to easily relapse and the like and is suitable for hyperuricemia treatment.
Description
Technical field
The present invention relates to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine composition for the treatment of hyperuricemia.
Background technology
Hyperuricemia is by purine metabolic disturbance and or the uric acid excretion disorder pathological changes that causes blood uric acid to raise.In recent years, along with economic development, dietary structure changes, and the sickness rate of hyperuricemia increases year by year, and normal associated with hypertension, hyperlipidemia, diabetes, coronary heart disease etc., is a potential threat to human health.Epidemiological study display domestic recently, the sickness rate of hyperuricemia is 10.1%, and has the trend of rejuvenation.Hyperuricemia rarely has relevant record in motherland's traditional medicine ancient books and records, and the lighter can non-evident sympton, and general visible body weight is weak, muddled not well or the nose heave or swollen sense in the whole body of the head, abundant expectoration, not resistance to work, or ambition is unhappy, or the strong pain in back, or spasm of the extremities etc., dysuria, stool is glutinous smelly not well, dimly red tongue has ecchymosis, or sublingual vein is dark, tongue fur BOHUANG or thick greasy, stringy and rolling pulse or puckery.Modern TCM clinical research is thought, its morbidity is how dirty with liver,spleen,kidney three, and wet, turbid, hot, the stasis of blood etc. is correlated with.Spleen lifting is had no right, the liver failing to maintain the normal flow of QI, and kidney qi is taken the photograph and received mistake department, and phlegm-turbidity and blood stasis poison is tied mutually, and internal injury is in kidney, and extrernal resistance causes in skeleton, meridians, joint etc.Tcm syndrome is broadly divided into the pattern of syndrome such as damp-heat accumulation, stagnation of phlegm-damp, stagnation of blood stasis and heat, the hepatic and renal YIN deficiency.
Hyperuricemia is at present without specific short, and routine medication many employings probenecid of hyperuricemia or benzbromarone promote urate excretion, and allopurinol suppresses uric acid synthesis.Probenecid and benzbromarone all can cause gastrointestinal reaction, and can promote that renal calculus is formed, and the crowds such as old people, hepatic and kidney function obstacle, renal calculus patient should not take; Allopurinol then has the side effect such as liver injury and cytopenia.In general, not only side effect is more for the conventional medicine of hyperuricemia, and has certain contraindication more, and patient is difficult to long-term taking and tolerance mostly.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of Chinese medicine composition of the treatment hyperuricemia adopting crude drug, compatibility reasonable, evident in efficacy.
In order to achieve the above object, the technical scheme that the present invention takes is:
A kind of Chinese medicine composition for the treatment of hyperuricemia, its component is by weight: Rhizoma Smilacis Glabrae 15 ~ 25 parts of Rhizoma Dioscoreae Septemlobae 10 ~ 20 parts, Semen Coicis 10 ~ 20 parts, the Radix Astragali 5 ~ 15 parts, Herba Leonuri 5 ~ 15 parts, Herba Lysimachiae 5 ~ 15 parts, Semen Plantaginis 3 ~ 7 parts, Radix Salviae Miltiorrhizae 3 ~ 7 parts, Radix Et Rhizoma Rhei 2 ~ 8 parts, 2 ~ 8 parts, Radix Glycyrrhizae.
As preferred component, its component is by weight: Rhizoma Smilacis Glabrae 17 ~ 23 parts of ， Rhizoma Dioscoreae Septemlobae 12 ~ 18 parts, Semen Coicis 12 ~ 18 parts, the Radix Astragali 7 ~ 13 parts, Herba Leonuri 7 ~ 13 parts, Herba Lysimachiae 7 ~ 13 parts, Semen Plantaginis 4 ~ 6 parts, Radix Salviae Miltiorrhizae 4 ~ 6 parts, Radix Et Rhizoma Rhei 3 ~ 7 parts, 3 ~ 7 parts, Radix Glycyrrhizae.
As preferred component, its component is by weight: Rhizoma Smilacis Glabrae 19 ~ 21 parts of ， Rhizoma Dioscoreae Septemlobae 14 ~ 16 parts, Semen Coicis 14 ~ 16 parts, the Radix Astragali 9 ~ 11 parts, Herba Leonuri 9 ~ 11 parts, Herba Lysimachiae 9 ~ 11 parts, Semen Plantaginis 5 ~ 6 parts, Radix Salviae Miltiorrhizae 4 ~ 5 parts, Radix Et Rhizoma Rhei 4 ~ 6 parts, 4 ~ 6 parts, Radix Glycyrrhizae.
As better composition, its component is by weight: Rhizoma Smilacis Glabrae 20 parts, leather Pi 15 parts, Semen Coicis 15 parts, the Radix Astragali 10 parts, Herba Leonuri 10 parts, Herba Lysimachiae 10 parts, Semen Plantaginis 5 parts, Radix Salviae Miltiorrhizae 5 parts, Radix Et Rhizoma Rhei 5 parts, 5 parts, Radix Glycyrrhizae.
This drug administration method: decocting fully mixes for 2 times afterwards, and extracting juice is about 400ml, each 1 time sooner or later, continues to take 30d.
Medicine of the present invention has following pharmacology:
Rhizoma Smilacis Glabrae, property of medicine sweet in the mouth, property are flat, have heat clearing away, removing toxic substances, effect except Xieri Wusu Symptom, improving eyesight, be mainly used in that heat in blood headache, laryngopharynx swelling and pain, menses are dripping, women's mass formed by blood stasis, vagina parasitosis, bag add heat syndrome, assist the symptoms such as day heat syndrome, syphilis, gonorrhea.
Rhizoma Dioscoreae Septemlobae, the property of medicine is bitter, flat, has wind-damp dispelling, effect that dampness removing is turbid, is mainly used in the symptoms such as stranguria marked by chyluria, nebulousurine, leukorrhagia, skin infection, eczema, rheumatic arthralgia.
Semen Coicis, the property of medicine is sweet, light, be slightly cold, and has effect of dampness removing spleen invigorating, arthralgia relieving by relaxing muscles and tendons, clearing away heat and discharging pus, is mainly used in the symptom such as edema, beriberi, dribbling urination, damp-warm diseases, leukorrhagia of having loose bowels, rheumatic arthralgia, the contracture of muscle arteries and veins, lung abscess, acute appendicitis, verruca plana.
The Radix Astragali, the property of medicine is sweet, tepor, there is effect of invigorating QI to consolidate the body surface resistance, hidroschesis detoxification, granulation promoting, diuresis, detumescent, be mainly used in that the deficiency of vital energy is weak, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, carbuncle difficulty are burst, burst for a long time do not hold back, the symptom such as blood deficiency and yellow complexion, interior-heat are quenched one's thirst, chronic nephritis, albuminuria, diabetes.
Herba Leonuri, property of medicine cold nature, bitter in the mouth, pungent, there is effect of promoting blood flow to regulate menstruation, inducing diuresis to remove edema, be mainly used in the symptoms such as menoxenia, dysmenorrhea, amenorrhea, lochiorrhea, edema oliguria, acute nephritis edema.
Herba Lysimachiae, sweet, the micro-hardship of the property of medicine, cool in nature, there is effect of relieving stranguria by diuresis, heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling, be mainly used in the symptom such as liver and gall and urinary system calculus, pyretic stranguria, oedema due to nephritis, jaundice due to damp-heat, sore carbuncle, venom, traumatic injury.
Semen Plantaginis, property of medicine cold nature, sweet in the mouth, there is clearing away heat and promoting diuresis, eliminating dampness by diuresis be treating stranguria, improving eyesight, the effect of eliminating the phlegm, be mainly used in redly swelling and ache edema distension, the puckery pain of pyretic stranguria, diarrhea due to summer heat and dampness, day, the symptom such as phlegm-heat cough.
Radix Salviae Miltiorrhizae, property of medicine bitter in the mouth, cold nature, there is effect of blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving, nourishing blood to tranquillize the mind, removing heat from blood eliminating carbuncle, be mainly used in menoxenia, dysmenorrhea, amenorrhea, the stagnant stomachache of the stasis of blood in puerperal, trusted subordinate's pain, lumps in the chest and abdomen, pyretic arthralgia swell and ache, the symptom such as traumatic injury, heat enter nutrient blood, dysphoria, vexed insomnia, carbuncle pyogenic infections from tumour or sore.
Radix Et Rhizoma Rhei, the property of medicine is bitter, cold in nature, there is the effect of attacking stagnant, clearing away damp-heat, pathogenic fire purging, removing heat from blood, blood stasis dispelling, removing toxic substances, be mainly used in excess-heat constipation, the accumulation of heat feeling of stuffiness in chest, damp-heat dysentery, jaundice, gonorrhea, edema abdominal distention, dysuria, conjunctival congestion, laryngopharynx swelling and pain, aphtha of the mouth and tongue, gastropyretic vomiting, haematemesis, spitting of blood, epistaxis, have blood in stool, hematuria, blood-retention, amenorrhea, the stagnant stomachache of the stasis of blood in puerperal, lumps in the chest and abdomen, traumatic injury, pyretic toxicity carbuncle and ulcer, erysipelas, the symptom such as scald.
Radix Glycyrrhizae, the property of medicine is sweet, flat, there is effect of QI invigorating invigorating middle warmer, relieving spasm to stop pain, nourishing the lung to arrest cough, eliminating fire and detoxication, coordinating the actions of various ingredients in a prescription, be mainly used in asthenia lack of appetite, the symptom such as leanness yellowish complexion, shortness of breath and palpitation, stomachache loose stool, the anxious pain of extremity contraction, hysteria, cough and asthma, laryngopharynx swelling and pain, carbuncle skin ulcer swell and ache, infantile carbuncle, medicine, alimentary toxicosis.
Compared with prior art, the benefit that the present invention has: the present invention adopts crude drug, originate extensively, cost is low, have no side effect, medical material formula is reasonable, make ingredients in curative effect, produce good synergism, jointly reach the effect with good detumescence, pain relieving, antiinflammatory, dampness removing.The present invention has that instant effect, cure rate are high, the not easily feature such as recurrence, is applicable to treat hyperuricemia.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
Patient data: patient 50 example, wherein man 45 example, female 5 example, at 32 ~ 72 years old age, the shortest person of the course of disease 1 month, most elder 7 years, be divided at random: treatment group 25 example, takes medicine of the present invention, each 1 time sooner or later, continues to take 30d; Matched group 25 example, gives existing medicine as crossed the western medicines such as probenecid sheet, allopurinol, 1 day 3 times, 7 days 1 courses for the treatment of.Two groups of data there was no significant differences such as sex, age, have comparability.
Efficacy assessment standard: diagnostic criteria, the disease of tcm Standardization of diagnosis and curative effect of People's Republic of China's traditional Chinese medicine industry standard that all cases is issued with reference to State Administration of Traditional Chinese Medicine determines diagnosis.
Effective: to treat blood uric acid <6.0mg/dL after 4 weeks, and be stable at this scope; Invalid: blood uric acid does not decline or declines to some extent, but level or higher before being returned to treatment after not returning back to normal or drug withdrawal.Treatment statistical result is as shown in the table:
| Group | Number of cases | Effective | Effectively | Invalid | Total effective rate |
| Treatment group | 25 | 17(68％) | 7(28％) | 1(4％) | 96％ |
| Matched group | 25 | 12(48％) | 7(28％) | 6(24％) | 76％ |
Visible, the medicine that the preferred embodiment for the present invention obtains can safe and effective treatment lumbago and skelalgia.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further described.
Embodiment 1
First, taking each component is by weight: Rhizoma Smilacis Glabrae 15 parts of ， Rhizoma Dioscoreae Septemlobae 10 parts, Semen Coicis 10 parts, the Radix Astragali 13, Herba Linderniae Crustaceae 13, Herba Lysimachiae 13 parts, Semen Plantaginis 6 parts, Radix Salviae Miltiorrhizae 6 parts, Radix Et Rhizoma Rhei 7 parts, 7 parts, Radix Glycyrrhizae.
Instructions of taking: decocting fully mixes for 2 times afterwards, and extracting juice is about 400ml, each 1 time sooner or later, continues to take 30d.
Embodiment 2
First, taking each component is by weight: Rhizoma Smilacis Glabrae 17 parts of ， Rhizoma Dioscoreae Septemlobae 14 parts, Semen Coicis 14 parts, the Radix Astragali 11, Herba Linderniae Crustaceae 11, Herba Lysimachiae 11 parts, Semen Plantaginis 5 parts, Radix Salviae Miltiorrhizae 5 parts, Radix Et Rhizoma Rhei 6 parts, 6 parts, Radix Glycyrrhizae.
Instructions of taking: with embodiment 1.
Embodiment 3
First, taking each component is by weight: Rhizoma Smilacis Glabrae 20 parts of ， Rhizoma Dioscoreae Septemlobae 15 parts, Semen Coicis 15 parts, the Radix Astragali 10, Herba Linderniae Crustaceae 10, Herba Lysimachiae 10 parts, Semen Plantaginis 5 parts, Radix Salviae Miltiorrhizae 5 parts, Radix Et Rhizoma Rhei 5 parts, 5 parts, Radix Glycyrrhizae.
Instructions of taking: with embodiment 1.
Embodiment 4
First, taking each component is by weight: Rhizoma Smilacis Glabrae 23 parts of ， Rhizoma Dioscoreae Septemlobae 18 parts, Semen Coicis 17 parts, the Radix Astragali 9, Herba Linderniae Crustaceae 9, Herba Lysimachiae 8 parts, Semen Plantaginis 4 parts, Radix Salviae Miltiorrhizae 4 parts, Radix Et Rhizoma Rhei 3 parts, 3 parts, Radix Glycyrrhizae.
Instructions of taking: with embodiment 1.
Embodiment 5
First, taking each component is by weight: Rhizoma Smilacis Glabrae 25 parts of ， Rhizoma Dioscoreae Septemlobae 20 parts, Semen Coicis 20 parts, the Radix Astragali 5 parts, Herba Linderniae Crustaceae 5 parts, Herba Lysimachiae 5 parts, Semen Plantaginis 3 parts, Radix Salviae Miltiorrhizae 3 parts, Radix Et Rhizoma Rhei 2 parts, 2 parts, Radix Glycyrrhizae.
Instructions of taking: with embodiment 1.
It should be pointed out that above case is only the representational example of the present invention.Obviously, technical scheme of the present invention is not limited to above-described embodiment, can also have many degeneration.
Claims (4)
1. treat the Chinese medicine composition of hyperuricemia for one kind, it is characterized in that, its component is by weight: Rhizoma Smilacis Glabrae 15 ~ 25 parts of ， Rhizoma Dioscoreae Septemlobae 10 ~ 20 parts, Semen Coicis 10 ~ 20 parts, the Radix Astragali 5 ~ 15 parts, Herba Leonuri 5 ~ 15 parts, Herba Lysimachiae 5 ~ 15 parts, Semen Plantaginis 3 ~ 7 parts, Radix Salviae Miltiorrhizae 3 ~ 7 parts, Radix Et Rhizoma Rhei 2 ~ 8 parts, 2 ~ 8 parts, Radix Glycyrrhizae.
2. a kind of Chinese medicine composition for the treatment of hyperuricemia according to claim 1, it is characterized in that, its component is by weight: Rhizoma Smilacis Glabrae 17 ~ 23 parts of ， Rhizoma Dioscoreae Septemlobae 12 ~ 18 parts, Semen Coicis 12 ~ 18 parts, the Radix Astragali 7 ~ 13 parts, Herba Leonuri 7 ~ 13 parts, Herba Lysimachiae 7 ~ 13 parts, Semen Plantaginis 4 ~ 6 parts, Radix Salviae Miltiorrhizae 4 ~ 6 parts, Radix Et Rhizoma Rhei 3 ~ 7 parts, 3 ~ 7 parts, Radix Glycyrrhizae.
3. a kind of Chinese medicine composition for the treatment of hyperuricemia according to claim 2, it is characterized in that, its component is by weight: Rhizoma Smilacis Glabrae 19 ~ 21 parts of ， Rhizoma Dioscoreae Septemlobae 14 ~ 16 parts, Semen Coicis 14 ~ 16 parts, the Radix Astragali 9 ~ 11 parts, Herba Leonuri 9 ~ 11 parts, Herba Lysimachiae 9 ~ 11 parts, Semen Plantaginis 5 ~ 6 parts, Radix Salviae Miltiorrhizae 4 ~ 5 parts, Radix Et Rhizoma Rhei 4 ~ 6 parts, 4 ~ 6 parts, Radix Glycyrrhizae.
4. described a kind of Chinese medicine composition for the treatment of hyperuricemia according to claim 3, it is characterized in that, its component is by weight: Rhizoma Smilacis Glabrae 20 parts, leather Pi 15 parts, Semen Coicis 15 parts, the Radix Astragali 10 parts, Herba Leonuri 10 parts, Herba Lysimachiae 10 parts, Semen Plantaginis 5 parts, Radix Salviae Miltiorrhizae 5 parts, Radix Et Rhizoma Rhei 5 parts, 5 parts, Radix Glycyrrhizae.
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| CN111759934A (en) * | 2020-07-02 | 2020-10-13 | 咸银库 | Traditional Chinese medicine formula for reducing uric acid and preparation process thereof |
| CN112717078A (en) * | 2021-01-26 | 2021-04-30 | 上海中医药大学 | Traditional Chinese medicine composition, preparation thereof, preparation method and application |
| CN114848746A (en) * | 2022-04-13 | 2022-08-05 | 华中农业大学 | Traditional Chinese medicine compound with effects of resisting hyperuricemia and gouty arthritis and preparation method and application thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105853811A (en) * | 2016-06-02 | 2016-08-17 | 罗汉武 | Traditional Chinese medicine composition for treating relatively high uric acid |
| CN106039131A (en) * | 2016-08-10 | 2016-10-26 | 郑州大学第附属医院 | Traditional Chinese medicinal compound preparation for treating IgA nephrosis with hyperuricemia, and preparation method and use thereof |
| CN106039131B (en) * | 2016-08-10 | 2019-11-22 | 郑州大学第一附属医院 | A traditional Chinese medicine compound preparation for treating IgA nephropathy complicated with hyperuricemia and its preparation method and application |
| CN106511498A (en) * | 2016-12-21 | 2017-03-22 | 四川何天祺医院管理有限公司 | Pharmaceutical composition for treating gout and bone diseases |
| CN106511498B (en) * | 2016-12-21 | 2020-02-14 | 四川何天祺医院管理有限公司 | Pharmaceutical composition for treating gout and bone diseases |
| CN109984239A (en) * | 2019-04-30 | 2019-07-09 | 桂林乐尔医疗器械有限公司 | A kind of deacidification shield kidney and strengthening spleen tea and the preparation method and application thereof |
| CN110742975A (en) * | 2019-11-22 | 2020-02-04 | 滕红丽 | Zhuang medicine preparation for preventing and treating hyperuricemia and preparation method thereof |
| CN110742975B (en) * | 2019-11-22 | 2021-06-08 | 滕红丽 | Zhuang medicine preparation for preventing and treating hyperuricemia and preparation method thereof |
| CN111759934A (en) * | 2020-07-02 | 2020-10-13 | 咸银库 | Traditional Chinese medicine formula for reducing uric acid and preparation process thereof |
| CN112717078A (en) * | 2021-01-26 | 2021-04-30 | 上海中医药大学 | Traditional Chinese medicine composition, preparation thereof, preparation method and application |
| CN114848746A (en) * | 2022-04-13 | 2022-08-05 | 华中农业大学 | Traditional Chinese medicine compound with effects of resisting hyperuricemia and gouty arthritis and preparation method and application thereof |
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