CN103751527A

CN103751527A - Traditional Chinese medicine composition for treating pulmonary fibrosis

Info

Publication number: CN103751527A
Application number: CN201410040088.XA
Authority: CN
Inventors: 王志军; 丛英珍
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-01-25
Filing date: 2014-01-25
Publication date: 2014-04-30

Abstract

The invention relates to a traditional Chinese medicine composition for treating pulmonary fibrosis, wherein the traditional Chinese medicine composition is prepared from the following raw medicines in ratio by weight: 4-6g of polygonatum, 6-9g of myrobalan, 4-6g of vine of multiflower knotweed, 6-8g of campsis grandiflora, 4-6g of plum blossom, 6-8g of mulberry leaf, 4-6g of lumbricus, 6-9g of herba saururi chinensis, 6-9g of calyx seu fructus physalis and 6-9g of hempleaf negundo chastetree leaf. The traditional Chinese medicine composition has effects of clearing heat, removing toxicity, boosting qi, nourishing yin, astringing lung, eliminating phlegm, activating blood and removing stasis; the traditional Chinese medicine composition is rapid in effect, good in curative effect and free in toxic and side effects; dialectical therapy of the traditional Chinese medicine is used in clinic according to different syndrome types.

Description

A kind of Chinese medicine composition for the treatment of pulmonary fibrosis

Technical field

Invention relates to a kind of Chinese medicine composition for the treatment of pulmonary fibrosis.

Background technology

As everyone knows, pulmonary fibrosis, lungs stroma consists of collagen protein, elastoidin and albumen carbohydrate, when fibroblast is subject to chemical or physical property injury, can secretes the repairing that collagen protein carries out interstitial tissue of lung, and then cause lungs fibrosis; Be after lungs come to harm, the result that human body reparation produces.Clinical manifestation: pulmonary fibrosis is many in the morbidity of 40-50 year, and male is mainly in women.Carrying out property is out of breath, abundant expectoration when dry cough, concurrent infection, pulmonary's moist rales or crepitation.The traditional Chinese medical science is thought: the cloudy wound of the dryness of the lung and asthenia-cold of lung-QI are the main aspects of pathogenesis, and it is scorching that this is more common in the plain body deficiency of YIN clinically, or because actute infection adds severe one, this is flaccidity syndrome of the lung due to deficiency-heat.Treat at present multiplex hormone, antibiotic therapy, hormone prolonged application is unfavorable to health.

Summary of the invention

Technical problem to be solved by this invention is in order to overcome technical deficiency, and a kind of Chinese medicine composition for the treatment of pulmonary fibrosis that curative effect is high, side effect is little is provided.

The technical scheme that its technical problem that the present invention solves adopts is to it is characterized in that being comprised of the crude drug component of following proportioning: Rhizoma Polygonati 4～6g, Fructus Chebulae 6～9g, Caulis Polygoni Multiflori 4～6g, Flos Campsis 6～8g, Flos Mume 4～6g, Folium Mori 6～8g, Pheretima 4～6g, Saururus chinensis 6～9g, Calyx Seu Fructus Physalis 6～9g, Folium Viticis Negundo 6～9g.

The invention has the beneficial effects as follows: there is heat-clearing and toxic substances removing, boosting qi and nourishing yin, astringe the lung eliminate the phlegm, the effect of promoting blood circulation to remove blood stasis, its effect is fast, curative effect is high, has no side effect.Clinically often according to different pattern of syndrome determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs.

Rhizoma Polygonati sweet in the mouth in Chinese medicine of the present invention, property is flat.Return spleen, lung, kidney channel.Function with cure mainly: boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney tonifying.For weakness of the spleen and stomach, fatigue and asthenia, xerostomia lack of appetite, deficiency of the lung cough caused by dryness, asthenia of essence and blood, interior-heat is quenched one's thirst.Modern study, has resisting pathogenic microbes, resisting fatigue, antivirus action.Male punishment leaf, function with cure mainly: eliminate the phlegm, cough-relieving, relievings asthma.For cough with asthma.Fructus Terminaliae Billericae bitter in the mouth, acid, puckery, property is flat.Return lung, large intestine channel.Function with cure mainly: astringing intestine to stop diarrhea is astringed the lung, pathogenic fire reducing sore-throat relieving.For chronic diarrhea chronic dysentery, the proctoptosis of having blood in stool, the deficiency of the lung is breathed with cough, and chronic cough is more than, pharyngalgia hoarseness.Caulis Polygoni Multiflori sweet in the mouth is flat.Function with cure mainly: nourishing blood to tranquillize the mind, dispelling wind and removing obstruction in the collateral.For insomnia and dreamful sleep, blood deficiency general pain, rheumatic arthralgia; External treatment skin pruritus.Flos Campsis nature and flavor are sweet, sour, cold.Function with cure mainly: removing heat from blood, blood stasis dispelling, dispels the wind.The function of Flos Mume with cure mainly: Ji strongly fragrant and in, reduce phlegm, removing toxic substances.For gloomy vexed, stomachache due to hyperactive liver-QI attacking the stomach, globus hystericus, scrofula sore.Folium Mori sweet in the mouth, hardship, cold in nature.Return lung, Liver Channel.Function with cure mainly: dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, liver heat removing and eyesight improving.For anemopyretic cold, lung-heat type cough, dizziness headache, conjunctival congestion is dim-sighted.Calyx Seu Fructus Physalis nature and flavor are bitter, cold in nature.Return lung meridian.Function with cure mainly: heat-clearing and toxic substances removing, sore-throat relieving, reduces phlegm, diuresis.For pharyngalgia hoarseness, phlegm-heat cough, dysuria; External treatment pemphigus, eczema.Saururus chinensis sweet in the mouth, pungent, cold in nature.Return lung, urinary bladder channel.Function with cure mainly: heat-clearing and toxic substances removing, inducing diuresis to remove edema.For dysuria, drench the puckery pain of drop, leucorrhea, urinary tract sense.Dye oedema due to nephritis; External treatment sore swollen toxin, eczema.All medicines match, bring out the best in each other above.

The present invention follows the prescriptions principle of the traditional Chinese medical science, is decocted in water for oral dose.The present invention is through clinical verification: cure rate 85.2%; Total effective rate 95.4%, toxic and side effects is little.

The specific embodiment

Below in conjunction with embodiment, the invention will be further described:

Embodiment 1: a kind of Chinese medicine composition of radiotherapy pulmonary fibrosis, is characterized in that by following proportioning weighting raw materials: Rhizoma Polygonati 4～6g, Fructus Chebulae 6～9g, Caulis Polygoni Multiflori 4～6g, Flos Campsis 6～8g, Flos Mume 4～6g, Folium Mori 6～8g, Pheretima 4～6g, Saururus chinensis 6～9g, Calyx Seu Fructus Physalis 6～9g, Folium Viticis Negundo 6～9g.

Embodiment 2: a kind of Chinese medicine composition of radiotherapy pulmonary fibrosis, is characterized in that by following proportioning weighting raw materials: Rhizoma Polygonati 4～6g, Fructus Chebulae 6g, Caulis Polygoni Multiflori 4～6g Flos Campsis 6～8g, Flos Mume 4～6g, Folium Mori 6～8g, Pheretima 4～6g, Saururus chinensis 6～9g Calyx Seu Fructus Physalis 6～9g, Folium Viticis Negundo 6～9g, Radix Platycodonis 6～9g.

Clinical efficacy is summed up:

One, physical data: selective emission pulmonary fibrosis patients is totally 68 examples, wherein: male 44 examples, female's 24 examples; In age 31-62 year, average 51 years old, in the course of disease 2 months, average 45.2 days, all through hospital above county level, make a definite diagnosis and implement above-mentioned treatment.

Two, precious disconnected standard: many amphitypys folder of holding concurrently clinically, many with showing as of lung yin virtual loss when the state of an illness is lighter, clinical manifestation: pulmonary fibrosis is many in the morbidity of 40-50 year, and male is mainly in women.Clinical manifestation.Carrying out property is out of breath, dry cough, pulmonary's moist rales or crepitation.X ray examination.Be in early days ground-glass appearance, typical case's change diffusivity linear, nodositas, cloud wadding sample, netted shade, lung volume dwindle.Lab testing: visible ESR, LDH increase, generally without Special Significance.Pulmonary function test: visible lung capacity reduces, diffusion reduces and hypoxemia.Lung biopsy provides pathology foundation.

Three, curative effect judging standard:

Cure: clinical symptoms disappears completely, and imaging examination pulmonary is normal.

Take a turn for the better: clinical symptoms is improved, and imaging examination pulmonary shadow alleviates.

Invalid: symptom is without improving or increasing the weight of.

Four, method of administration: all crude drug of the present invention are chosen, mixed add decocting after immersion and become decoction, every dose of 200m1, every day 2 times, early, late sub-service.

Five, therapeutic effect: the present invention treats 68 routine patients: wherein cure 58 examples, 7 examples that take a turn for the better, 3 examples more, cure rate 85.2%; Total effective rate 95.5%.

Six, model case

1, Lee XX, man, 46 years old, in February, 2011 was medical.Main suit's lung cancer with brain metastasis tumor postoperation radiotherapy is after 28 days, because of cough, expectoration, pant 1 week, through taking cephamycin capsule and cough mixture poor effect, auscultation: dry, moist rales appear in pulmonary, X-ray examination: blur margin shade appears in exposure pulmonary, prompting radiation fibrosis of lung.Patient requires to take 15 doses, Chinese medicine of the present invention, and clinical symptoms disappears completely, and X-ray examination pulmonary is normal.So far not recurrence.

2, clump XX, female, 46 years old, in June, 2012 was medical.Patient main suit's postoperation radiotherapy 20 days, coughs, coughs a small amount of white sputum crudum, uncomfortable in chest, chest pain sometimes.X-ray examination: netted, the irregular fuzzy dog shade in edge, pulmonary fibrosis appear in pulmonary.Through taking 20 doses, Chinese medicine of the present invention, remission, drug withdrawal 2 days, continued to take 1 course for the treatment of, and 15 doses, clinical symptoms disappears completely, and X-ray examination is slight.So far not recurrence.

3, Liu XX, female, 68 years old, in February, 2013 was just precious, breast carcinoma month after operation, after radiotherapy 1 week, because of dry cough, chest pain.Have a medical check-up: dry rale appears in pulmonary, X-ray examination: prompting has pulmonary fibrosis.Patient requires to take after 20 doses, Chinese medicine of the present invention drug withdrawal 2 days, takes again 10 doses, and clinical symptoms disappears completely, and X-ray examination pulmonary is normal.So far not recurrence.

Claims

1. treat a Chinese medicine composition for pulmonary fibrosis, it is characterized in that being made by the material medicine of following weight proportion: Rhizoma Polygonati 4～6g, Fructus Chebulae 6～9g Caulis Polygoni Multiflori 4～6g, Flos Campsis 6～8g, Flos Mume 4～6g, Folium Mori 6～8g, Pheretima 4～6g, Saururus chinensis 6～9g, Calyx Seu Fructus Physalis 6～9g, Folium Viticis Negundo 6～9.