CN103750307A - Yam hawthorn dispersible tablet and preparation method thereof - Google Patents
Yam hawthorn dispersible tablet and preparation method thereof Download PDFInfo
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- CN103750307A CN103750307A CN201310748590.1A CN201310748590A CN103750307A CN 103750307 A CN103750307 A CN 103750307A CN 201310748590 A CN201310748590 A CN 201310748590A CN 103750307 A CN103750307 A CN 103750307A
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- 235000013204 Crataegus X haemacarpa Nutrition 0.000 title claims abstract description 72
- 235000009685 Crataegus X maligna Nutrition 0.000 title claims abstract description 72
- 235000009444 Crataegus X rubrocarnea Nutrition 0.000 title claims abstract description 72
- 235000009486 Crataegus bullatus Nutrition 0.000 title claims abstract description 72
- 235000017181 Crataegus chrysocarpa Nutrition 0.000 title claims abstract description 72
- 235000009682 Crataegus limnophila Nutrition 0.000 title claims abstract description 72
- 235000004423 Crataegus monogyna Nutrition 0.000 title claims abstract description 72
- 235000002313 Crataegus paludosa Nutrition 0.000 title claims abstract description 72
- 235000009840 Crataegus x incaedua Nutrition 0.000 title claims abstract description 72
- 238000002360 preparation method Methods 0.000 title claims description 12
- 239000007919 dispersible tablet Substances 0.000 title abstract 3
- 240000000171 Crataegus monogyna Species 0.000 title 1
- 241001092040 Crataegus Species 0.000 claims abstract description 72
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract description 44
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 41
- 239000000843 powder Substances 0.000 claims abstract description 32
- 235000004879 dioscorea Nutrition 0.000 claims abstract description 27
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims abstract description 22
- 229930003268 Vitamin C Natural products 0.000 claims abstract description 22
- 235000019154 vitamin C Nutrition 0.000 claims abstract description 22
- 239000011718 vitamin C Substances 0.000 claims abstract description 22
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims abstract description 14
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims abstract description 13
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims abstract description 13
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims abstract description 13
- 240000005373 Panax quinquefolius Species 0.000 claims abstract description 13
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 13
- 229920002472 Starch Polymers 0.000 claims abstract description 13
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 claims abstract description 13
- WHMDKBIGKVEYHS-IYEMJOQQSA-L Zinc gluconate Chemical compound [Zn+2].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O WHMDKBIGKVEYHS-IYEMJOQQSA-L 0.000 claims abstract description 13
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims abstract description 13
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims abstract description 13
- 150000004676 glycans Chemical class 0.000 claims abstract description 13
- 235000020717 hawthorn extract Nutrition 0.000 claims abstract description 13
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims abstract description 13
- 229920001282 polysaccharide Polymers 0.000 claims abstract description 13
- 239000005017 polysaccharide Substances 0.000 claims abstract description 13
- 239000011734 sodium Substances 0.000 claims abstract description 13
- 229910052708 sodium Inorganic materials 0.000 claims abstract description 13
- 235000019698 starch Nutrition 0.000 claims abstract description 13
- 235000019408 sucralose Nutrition 0.000 claims abstract description 13
- 235000019155 vitamin A Nutrition 0.000 claims abstract description 13
- 239000011719 vitamin A Substances 0.000 claims abstract description 13
- 229940045997 vitamin a Drugs 0.000 claims abstract description 13
- 235000011478 zinc gluconate Nutrition 0.000 claims abstract description 13
- 239000011670 zinc gluconate Substances 0.000 claims abstract description 13
- 229960000306 zinc gluconate Drugs 0.000 claims abstract description 13
- 239000004376 Sucralose Substances 0.000 claims abstract description 8
- 239000001768 carboxy methyl cellulose Substances 0.000 claims abstract description 8
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims abstract description 8
- RQFQJYYMBWVMQG-IXDPLRRUSA-N chitotriose Chemical compound O[C@@H]1[C@@H](N)[C@H](O)O[C@H](CO)[C@H]1O[C@H]1[C@H](N)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)N)[C@@H](CO)O1 RQFQJYYMBWVMQG-IXDPLRRUSA-N 0.000 claims abstract description 8
- 239000008108 microcrystalline cellulose Substances 0.000 claims abstract description 8
- 229940016286 microcrystalline cellulose Drugs 0.000 claims abstract description 8
- 239000008107 starch Substances 0.000 claims abstract description 8
- BAQAVOSOZGMPRM-QBMZZYIRSA-N sucralose Chemical compound O[C@@H]1[C@@H](O)[C@@H](Cl)[C@@H](CO)O[C@@H]1O[C@@]1(CCl)[C@@H](O)[C@H](O)[C@@H](CCl)O1 BAQAVOSOZGMPRM-QBMZZYIRSA-N 0.000 claims abstract description 8
- 235000002722 Dioscorea batatas Nutrition 0.000 claims description 45
- 235000006536 Dioscorea esculenta Nutrition 0.000 claims description 45
- 240000001811 Dioscorea oppositifolia Species 0.000 claims description 45
- 235000003416 Dioscorea oppositifolia Nutrition 0.000 claims description 45
- 238000002791 soaking Methods 0.000 claims description 28
- 235000013312 flour Nutrition 0.000 claims description 19
- 239000000203 mixture Substances 0.000 claims description 17
- 239000007864 aqueous solution Substances 0.000 claims description 14
- 235000009508 confectionery Nutrition 0.000 claims description 12
- 239000000741 silica gel Substances 0.000 claims description 12
- 229910002027 silica gel Inorganic materials 0.000 claims description 12
- 238000002156 mixing Methods 0.000 claims description 10
- 239000002245 particle Substances 0.000 claims description 10
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 claims description 7
- 238000005202 decontamination Methods 0.000 claims description 7
- 230000003588 decontaminative effect Effects 0.000 claims description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- PTHCMJGKKRQCBF-UHFFFAOYSA-N Cellulose, microcrystalline Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC)C(CO)O1 PTHCMJGKKRQCBF-UHFFFAOYSA-N 0.000 claims description 5
- 229920001661 Chitosan Polymers 0.000 claims description 5
- 229940105329 carboxymethylcellulose Drugs 0.000 claims description 5
- 238000001035 drying Methods 0.000 claims description 5
- 238000005469 granulation Methods 0.000 claims description 5
- 230000003179 granulation Effects 0.000 claims description 5
- 239000012535 impurity Substances 0.000 claims description 5
- 229920001542 oligosaccharide Polymers 0.000 claims description 5
- 150000002482 oligosaccharides Chemical class 0.000 claims description 5
- 238000011084 recovery Methods 0.000 claims description 5
- 239000000126 substance Substances 0.000 claims description 5
- 238000001291 vacuum drying Methods 0.000 claims description 5
- 229930003231 vitamin Natural products 0.000 claims description 5
- 235000013343 vitamin Nutrition 0.000 claims description 5
- 239000011782 vitamin Substances 0.000 claims description 5
- 229940088594 vitamin Drugs 0.000 claims description 5
- 150000003722 vitamin derivatives Chemical class 0.000 claims description 5
- 206010012735 Diarrhoea Diseases 0.000 abstract description 6
- 210000000952 spleen Anatomy 0.000 abstract description 6
- 230000029087 digestion Effects 0.000 abstract description 3
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 abstract 2
- 235000014493 Crataegus Nutrition 0.000 abstract 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 abstract 1
- 229930195725 Mannitol Natural products 0.000 abstract 1
- 208000019902 chronic diarrheal disease Diseases 0.000 abstract 1
- 235000019441 ethanol Nutrition 0.000 abstract 1
- 235000019359 magnesium stearate Nutrition 0.000 abstract 1
- 239000000594 mannitol Substances 0.000 abstract 1
- 235000010355 mannitol Nutrition 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 239000000377 silicon dioxide Substances 0.000 abstract 1
- 238000005728 strengthening Methods 0.000 abstract 1
- 208000019637 Infantile Diarrhea Diseases 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 230000001142 anti-diarrhea Effects 0.000 description 2
- 235000005911 diet Nutrition 0.000 description 2
- 230000000378 dietary effect Effects 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000003014 reinforcing effect Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000013872 defecation Effects 0.000 description 1
- 230000006735 deficit Effects 0.000 description 1
- 201000006549 dyspepsia Diseases 0.000 description 1
- 235000013402 health food Nutrition 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 238000004393 prognosis Methods 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 229940126672 traditional medicines Drugs 0.000 description 1
- 230000001131 transforming effect Effects 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L19/00—Products from fruits or vegetables; Preparation or treatment thereof
- A23L19/09—Mashed or comminuted products, e.g. pulp, purée, sauce, or products made therefrom, e.g. snacks
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L19/00—Products from fruits or vegetables; Preparation or treatment thereof
- A23L19/10—Products from fruits or vegetables; Preparation or treatment thereof of tuberous or like starch containing root crops
- A23L19/12—Products from fruits or vegetables; Preparation or treatment thereof of tuberous or like starch containing root crops of potatoes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Chemical & Material Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Botany (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Mycology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
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Abstract
The invention discloses a yam hawthorn dispersible tablet which comprises the following components in parts by weight: 300 to 500 parts of fresh yams, 300 to 500 parts of hawthorns, 1.75 to 3.75 parts of vitamin C, 0.01 to 0.02 part of vitamin A, 0.15 to 0.35 parts of zinc gluconate, 40 to 60 parts of microcrystalline cellulose, 0.12 to 0.32 part of hawthorn extract, 0.12 to 0.32 part of American ginseng extract, 100 to 170 parts of mannitol, 1.2 to 3.2 parts of chitosan oligosaccharide, 1.2 to 3.2 parts of crude polysaccharide, 10 to 15 parts of sucralose, 10 to 50 parts of superfine silica powder, 3 to 5 parts of carboxymethyl cellulose, 55 to 80 parts of sodium carboxymethyl starch, 4 to 6 parts of magnesium stearate and a proper amount of 75% ethyl alcohol. The yam hawthorn dispersible tablet has the functions of strengthening the spleen to help digestion and regulating the middle warmer to cure diarrhea, thereby being suitable for chronic diarrhea of infants.
Description
Technical field
The invention belongs to nutritional health food field, be specially a kind of Chinese yam hawthorn dispersing tablet and preparation method.
Background technology
Infantile diarrhea is to increase with times of defecation, and excrement matter is thin or as water sample a kind of common disease in children that is feature.Doctor trained in Western medicine claims to have loose bowels into diarrhoea, sends out and claims infantile diarrhea in infant person.This disease is the most common with 2 years old following children's.Though all can occur throughout the year, take summer and autumn the incidence of disease as high, what autumn and winter season occurred has loose bowels, and easily causes popular.Children's's asthenic susceptibility of spleen, internal damage caused by infantile dyspepsia, or the insufficiency of both the spleen and the kindey, all can cause transporting and transforming function of the spleen and stomach functional disturbance and have loose bowels.The lighter treats proper, prognosis bona.Severe one is let out lower excessive, easily sees impairment of both QI and YIN, even yin and yang exhausted simultaneously.Although also have Chinese Traditional Medicines or the formula of a lot of infantile diarrheas at present, although treatment prescribed preparation is a lot, be all to occur with the form of medicine, the dietary product that is applicable to long-term edible auxiliary curing is little.Therefore the dietary product of researching and developing a kind of safe auxiliary curing is very with practical value.
Summary of the invention
For above-mentioned situation, technical problem solved by the invention is to provide a kind of Chinese yam hawthorn dispersing tablet and preparation method who is applicable to reinforcing spleen to promote digestion and middle antidiarrheal, to solve the problem proposing in above-mentioned background technology.
For achieving the above object, the invention provides following technical scheme:
A kind of Chinese yam hawthorn dispersing tablet, comprise following weight portion composition: fresh Chinese yam 300-500 part, hawthorn 300-500 part, vitamin C 1.75-3.75 part, vitamin A 0.01-0.02 part, zinc gluconate 0.15-0.35 part, microcrystalline cellulose 40-60 part, haw thorn extract 0.12-0.32 part, American ginseng extract 0.12-0.32 part, sweet mellow wine 100-170 part, chitosan oligosaccharide 1.2-3.2 part, thick polysaccharide 1.2-3.2 part, Sucralose 10-15 part, superfine silica gel powder 10-50 part, carboxymethyl cellulose 3-5 part, sodium carboxymethyl starch 55-80 part, dolomol 4-6 part, 75% concentration ethanol is appropriate.
As preferably, described a kind of Chinese yam hawthorn dispersing tablet, comprises following weight portion composition: 400 parts of fresh Chinese yams, 400 parts of hawthorn, 2.75 parts of vitamin Cs, 0.015 part of vitamin A, 0.25 part of zinc gluconate, 50 parts of microcrystalline celluloses, 0.22 part of haw thorn extract, 0.22 part of American ginseng extract, 135 parts, sweet mellow wine, 2.2 parts of chitosan oligosaccharides, 2.2 parts of thick polysaccharide, 12.5 parts of Sucraloses, 30 parts of superfine silica gel powders, 4 parts of carboxymethyl celluloses, 67.5 parts of sodium carboxymethyl starches, 5 parts of dolomols, 75% concentration ethanol are appropriate.
A preparation method for Chinese yam hawthorn dispersing tablet, comprises the following steps:
(1) get fresh Chinese yam and clean, peeling with soaking 6-8min in the concentration 0.2% vitamin C aqueous solution, is cured the Chinese yam after soaking and is made dry Chinese yam within the scope of 80-100 ℃, and dry yam flour is broken into 300-400 object yam flour, standby;
(2) get fresh hawthorn stoning decontamination and clean, with soaking 6-8min in the concentration 0.2% vitamin C aqueous solution, the hawthorn after soaking is cured and makes dry hawthorn within the scope of 80-100 ℃, will do hawthorn powder and be broken into 300-400 object hawthorn powder, standby;
(3) gained hawthorn powder in step (1) gained yam flour and step (2) is uniformly mixed, mixer speed is 50-75r/min, and the time is 10-15min, obtains mixture I, standby;
(4) to the middle gained mixture I of step (3), add ethanol to make determining alcohol reach 75%, after standing 8-16h, filter, impurity is discharged, after recovery ethanol, at temperature 40-60 ℃, under vacuum 0.58-0.68MPa condition, Vacuum Concentration to dry substance reaches 50-70%, carry out again vacuum drying, within the scope of baking temperature 40-60 ℃, obtain dry extract, standby;
(5) after being pulverized, step (4) gained dry extract add vitamin C, vitamin A, zinc gluconate, carboxymethyl cellulose, microcrystalline cellulose, haw thorn extract, American ginseng extract, sweet mellow wine, chitosan oligosaccharide, thick polysaccharide, Sucralose, superfine silica gel powder mixing machine to mix granulation, rotating speed is 10-15r/min, time is 6-8min, by the particle after mixing 50-60 ℃ of scope inner drying to water content between 1-3%, standby;
(6) to the middle gained particle of step (5), add sodium carboxymethyl starch, dolomol to mix, compacting in flakes, obtains Chinese yam hawthorn dispersing tablet.
In described step (1), get fresh Chinese yam and clean, peeling with soaking 8min in the concentration 0.2% vitamin C aqueous solution, is cured the Chinese yam after soaking and is made dry Chinese yam within the scope of 100 ℃, and dry yam flour is broken into 400 object yam flours.
In described step (2), get fresh hawthorn stoning decontamination and clean, with soaking 8min in the concentration 0.2% vitamin C aqueous solution, the hawthorn after soaking is cured and makes dry hawthorn within the scope of 100 ℃, will do hawthorn powder and be broken into 400 object hawthorn powder.
In sum, beneficial effect of the present invention:
The present invention has reinforcing spleen to promote digestion, and middle antidiarrheal, is applicable to children's and rushes down for a long time.
The specific embodiment
Below in conjunction with the embodiment of the present invention, gained technical scheme in the embodiment of the present invention is clearly and completely described, obviously, described embodiment is only the present invention's part embodiment, rather than whole embodiment.Based on gained embodiment in the present invention, those of ordinary skills, not making the every other embodiment obtaining under creative work prerequisite, belong to the scope of protection of the invention.
Embodiment 1
A kind of Chinese yam hawthorn dispersing tablet, comprises following weight portion composition: 300 parts of fresh Chinese yams, 300 parts of hawthorn, 1.75 parts of vitamin Cs, 0.01 part of vitamin A, 0.15 part of zinc gluconate, 40 parts of microcrystalline celluloses, 0.12 part of haw thorn extract, 0.12 part of American ginseng extract, 100 parts, sweet mellow wine, 1.2 parts of chitosan oligosaccharides, 1.2 parts of thick polysaccharide, 10 parts of Sucraloses, 10 parts of superfine silica gel powders, 3 parts of carboxymethyl celluloses, 55 parts of sodium carboxymethyl starches, 4 parts of dolomols, 75% concentration ethanol are appropriate.
A preparation method for Chinese yam hawthorn dispersing tablet, comprises the following steps:
(1) get fresh Chinese yam and clean, peeling with soaking 6-8min in the concentration 0.2% vitamin C aqueous solution, is cured the Chinese yam after soaking and is made dry Chinese yam within the scope of 80-100 ℃, and dry yam flour is broken into 300-400 object yam flour, standby;
(2) get fresh hawthorn stoning decontamination and clean, with soaking 6-8min in the concentration 0.2% vitamin C aqueous solution, the hawthorn after soaking is cured and makes dry hawthorn within the scope of 80-100 ℃, will do hawthorn powder and be broken into 300-400 object hawthorn powder, standby;
(3) gained hawthorn powder in step (1) gained yam flour and step (2) is uniformly mixed, mixer speed is 50-75r/min, and the time is 10-15min, obtains mixture I, standby;
(4) to the middle gained mixture I of step (3), add ethanol to make determining alcohol reach 75%, after standing 8-16h, filter, impurity is discharged, after recovery ethanol, at temperature 40-60 ℃, under vacuum 0.58-0.68MPa condition, Vacuum Concentration to dry substance reaches 50-70%, carry out again vacuum drying, within the scope of baking temperature 40-60 ℃, obtain dry extract, standby;
(5) after being pulverized, step (4) gained dry extract add vitamin C, vitamin A, zinc gluconate, carboxymethyl cellulose, microcrystalline cellulose, haw thorn extract, American ginseng extract, sweet mellow wine, chitosan oligosaccharide, thick polysaccharide, Sucralose, superfine silica gel powder mixing machine to mix granulation, rotating speed is 10-15r/min, time is 6-8min, by the particle after mixing 50-60 ℃ of scope inner drying to water content between 1-3%, standby;
(6) to the middle gained particle of step (5), add sodium carboxymethyl starch, dolomol to mix, compacting in flakes, obtains Chinese yam hawthorn dispersing tablet.
Embodiment 2
A kind of Chinese yam hawthorn dispersing tablet, comprises following weight portion composition: 400 parts of fresh Chinese yams, 400 parts of hawthorn, 2.75 parts of vitamin Cs, 0.015 part of vitamin A, 0.25 part of zinc gluconate, 50 parts of microcrystalline celluloses, 0.22 part of haw thorn extract, 0.22 part of American ginseng extract, 135 parts, sweet mellow wine, 2.2 parts of chitosan oligosaccharides, 2.2 parts of thick polysaccharide, 12.5 parts of Sucraloses, 30 parts of superfine silica gel powders, 4 parts of carboxymethyl celluloses, 67.5 parts of sodium carboxymethyl starches, 5 parts of dolomols, 75% concentration ethanol are appropriate.
A preparation method for Chinese yam hawthorn dispersing tablet, comprises the following steps:
(1) get fresh Chinese yam and clean, peeling with soaking 6-8min in the concentration 0.2% vitamin C aqueous solution, is cured the Chinese yam after soaking and is made dry Chinese yam within the scope of 80-100 ℃, and dry yam flour is broken into 300-400 object yam flour, standby;
(2) get fresh hawthorn stoning decontamination and clean, with soaking 6-8min in the concentration 0.2% vitamin C aqueous solution, the hawthorn after soaking is cured and makes dry hawthorn within the scope of 80-100 ℃, will do hawthorn powder and be broken into 300-400 object hawthorn powder, standby;
(3) gained hawthorn powder in step (1) gained yam flour and step (2) is uniformly mixed, mixer speed is 50-75r/min, and the time is 10-15min, obtains mixture I, standby;
(4) to the middle gained mixture I of step (3), add ethanol to make determining alcohol reach 75%, after standing 8-16h, filter, impurity is discharged, after recovery ethanol, at temperature 40-60 ℃, under vacuum 0.58-0.68MPa condition, Vacuum Concentration to dry substance reaches 50-70%, carry out again vacuum drying, within the scope of baking temperature 40-60 ℃, obtain dry extract, standby;
(5) after being pulverized, step (4) gained dry extract add vitamin C, vitamin A, zinc gluconate, carboxymethyl cellulose, microcrystalline cellulose, haw thorn extract, American ginseng extract, sweet mellow wine, chitosan oligosaccharide, thick polysaccharide, Sucralose, superfine silica gel powder mixing machine to mix granulation, rotating speed is 10-15r/min, time is 6-8min, by the particle after mixing 50-60 ℃ of scope inner drying to water content between 1-3%, standby;
(6) to the middle gained particle of step (5), add sodium carboxymethyl starch, dolomol to mix, compacting in flakes, obtains Chinese yam hawthorn dispersing tablet.
Embodiment 3
A kind of Chinese yam hawthorn dispersing tablet, comprises following weight portion composition: 500 parts of fresh Chinese yams, 500 parts of hawthorn, 3.75 parts of vitamin Cs, 0.02 part of vitamin A, 0.35 part of zinc gluconate, 60 parts of microcrystalline celluloses, 0.32 part of haw thorn extract, 0.32 part of American ginseng extract, 170 parts, sweet mellow wine, 3.2 parts of chitosan oligosaccharides, 3.2 parts of thick polysaccharide, 15 parts of Sucraloses, 50 parts of superfine silica gel powders, 5 parts of carboxymethyl celluloses, 80 parts of sodium carboxymethyl starches, 6 parts of dolomols, 75% concentration ethanol are appropriate.
A preparation method for Chinese yam hawthorn dispersing tablet, comprises the following steps:
(1) get fresh Chinese yam and clean, peeling with soaking 6-8min in the concentration 0.2% vitamin C aqueous solution, is cured the Chinese yam after soaking and is made dry Chinese yam within the scope of 80-100 ℃, and dry yam flour is broken into 300-400 object yam flour, standby;
(2) get fresh hawthorn stoning decontamination and clean, with soaking 6-8min in the concentration 0.2% vitamin C aqueous solution, the hawthorn after soaking is cured and makes dry hawthorn within the scope of 80-100 ℃, will do hawthorn powder and be broken into 300-400 object hawthorn powder, standby;
(3) gained hawthorn powder in step (1) gained yam flour and step (2) is uniformly mixed, mixer speed is 50-75r/min, and the time is 10-15min, obtains mixture I, standby;
(4) to the middle gained mixture I of step (3), add ethanol to make determining alcohol reach 75%, after standing 8-16h, filter, impurity is discharged, after recovery ethanol, at temperature 40-60 ℃, under vacuum 0.58-0.68MPa condition, Vacuum Concentration to dry substance reaches 50-70%, carry out again vacuum drying, within the scope of baking temperature 40-60 ℃, obtain dry extract, standby;
(5) after being pulverized, step (4) gained dry extract add vitamin C, vitamin A, zinc gluconate, carboxymethyl cellulose, microcrystalline cellulose, haw thorn extract, American ginseng extract, sweet mellow wine, chitosan oligosaccharide, thick polysaccharide, Sucralose, superfine silica gel powder mixing machine to mix granulation, rotating speed is 10-15r/min, time is 6-8min, by the particle after mixing 50-60 ℃ of scope inner drying to water content between 1-3%, standby;
(6) to the middle gained particle of step (5), add sodium carboxymethyl starch, dolomol to mix, compacting in flakes, obtains Chinese yam hawthorn dispersing tablet.
To those skilled in the art, obviously the invention is not restricted to the details of above-mentioned example embodiment, and in the situation that not deviating from spirit of the present invention or essential characteristic, can realize the present invention with other concrete form.Therefore, no matter from which point, all should regard embodiment as exemplary, and be nonrestrictive, scope of the present invention is limited by claims rather than above-mentioned explanation, is therefore intended to all changes that drop in the implication and the scope that are equal to important document of claim to include in the present invention.
In addition, be to be understood that, although this description is described according to embodiment, but be not that each embodiment only comprises an independently technical scheme, this narrating mode of description is only for clarity sake, those skilled in the art should make description as a whole, and in each embodiment, gained technical scheme also can, through appropriately combined, form other embodiments that it will be appreciated by those skilled in the art that.
Claims (5)
1. a Chinese yam hawthorn dispersing tablet, it is characterized in that: comprise following weight portion composition: fresh Chinese yam 300-500 part, hawthorn 300-500 part, vitamin C 1.75-3.75 part, vitamin A 0.01-0.02 part, zinc gluconate 0.15-0.35 part, microcrystalline cellulose 40-60 part, haw thorn extract 0.12-0.32 part, American ginseng extract 0.12-0.32 part, sweet mellow wine 100-170 part, chitosan oligosaccharide 1.2-3.2 part, thick polysaccharide 1.2-3.2 part, Sucralose 10-15 part, superfine silica gel powder 10-50 part, carboxymethyl cellulose 3-5 part, sodium carboxymethyl starch 55-80 part, dolomol 4-6 part, 75% concentration ethanol is appropriate.
2. a kind of Chinese yam hawthorn dispersing tablet according to claim 1, is characterized in that: comprise following weight portion composition: 400 parts of fresh Chinese yams, 400 parts of hawthorn, 2.75 parts of vitamin Cs, 0.015 part of vitamin A, 0.25 part of zinc gluconate, 50 parts of microcrystalline celluloses, 0.22 part of haw thorn extract, 0.22 part of American ginseng extract, 135 parts, sweet mellow wine, 2.2 parts of chitosan oligosaccharides, 2.2 parts of thick polysaccharide, 12.5 parts of Sucraloses, 30 parts of superfine silica gel powders, 4 parts of carboxymethyl celluloses, 67.5 parts of sodium carboxymethyl starches, 5 parts of dolomols, 75% concentration ethanol are appropriate.
3. a preparation method for Chinese yam hawthorn dispersing tablet, is characterized in that: comprise the following steps:
(1) get fresh Chinese yam and clean, peeling with soaking 6-8min in the concentration 0.2% vitamin C aqueous solution, is cured the Chinese yam after soaking and is made dry Chinese yam within the scope of 80-100 ℃, and dry yam flour is broken into 300-400 object yam flour, standby;
(2) get fresh hawthorn stoning decontamination and clean, with soaking 6-8min in the concentration 0.2% vitamin C aqueous solution, the hawthorn after soaking is cured and makes dry hawthorn within the scope of 80-100 ℃, will do hawthorn powder and be broken into 300-400 object hawthorn powder, standby;
(3) gained hawthorn powder in step (1) gained yam flour and step (2) is uniformly mixed, mixer speed is 50-75r/min, and the time is 10-15min, obtains mixture I, standby;
(4) to the middle gained mixture I of step (3), add ethanol to make determining alcohol reach 75%, after standing 8-16h, filter, impurity is discharged, after recovery ethanol, at temperature 40-60 ℃, under vacuum 0.58-0.68MPa condition, Vacuum Concentration to dry substance reaches 50-70%, carry out again vacuum drying, within the scope of baking temperature 40-60 ℃, obtain dry extract, standby;
(5) after being pulverized, step (4) gained dry extract add vitamin C, vitamin A, zinc gluconate, carboxymethyl cellulose, microcrystalline cellulose, haw thorn extract, American ginseng extract, sweet mellow wine, chitosan oligosaccharide, thick polysaccharide, Sucralose, superfine silica gel powder mixing machine to mix granulation, rotating speed is 10-15r/min, time is 6-8min, by the particle after mixing 50-60 ℃ of scope inner drying to water content between 1-3%, standby;
(6) to the middle gained particle of step (5), add sodium carboxymethyl starch, dolomol to mix, compacting in flakes, obtains Chinese yam hawthorn dispersing tablet.
4. the preparation method of a kind of Chinese yam hawthorn dispersing tablet according to claim 3, it is characterized in that: in described step (1), get fresh Chinese yam and clean, peeling, with soaking 8min in the concentration 0.2% vitamin C aqueous solution, Chinese yam after soaking is cured and makes dry Chinese yam within the scope of 100 ℃, dry yam flour is broken into 400 object yam flours.
5. the preparation method of a kind of Chinese yam hawthorn dispersing tablet according to claim 3, it is characterized in that: in described step (2), get fresh hawthorn stoning decontamination and clean, with soaking 8min in the concentration 0.2% vitamin C aqueous solution, hawthorn after soaking is cured and makes dry hawthorn within the scope of 100 ℃, will do hawthorn powder and be broken into 400 object hawthorn powder.
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| CN110463891A (en) * | 2018-05-10 | 2019-11-19 | 贺州学院 | A kind of processing method of Chinese yam fructus crataegi pinnatifidae compound solid beverage |
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| CN1245703A (en) * | 1998-11-18 | 2000-03-01 | 李乐 | Nutrient health-care tea |
| CN103356933A (en) * | 2013-07-18 | 2013-10-23 | 苏州市天灵中药饮片有限公司 | Stomach-nourishing spleen-strengthening chewing tablets and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1245703A (en) * | 1998-11-18 | 2000-03-01 | 李乐 | Nutrient health-care tea |
| CN103356933A (en) * | 2013-07-18 | 2013-10-23 | 苏州市天灵中药饮片有限公司 | Stomach-nourishing spleen-strengthening chewing tablets and preparation method thereof |
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| 陈奇等: "健胃消食片", 《中药新药与临床药理》 * |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN110463891A (en) * | 2018-05-10 | 2019-11-19 | 贺州学院 | A kind of processing method of Chinese yam fructus crataegi pinnatifidae compound solid beverage |
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