CN103783518B - A kind of Rhizoma Zingiberis Recens Fructus Jujubae Chinese yam dispersible tablet and preparation method - Google Patents
A kind of Rhizoma Zingiberis Recens Fructus Jujubae Chinese yam dispersible tablet and preparation method Download PDFInfo
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- 240000001811 Dioscorea oppositifolia Species 0.000 title claims abstract description 24
- 235000003416 Dioscorea oppositifolia Nutrition 0.000 title claims abstract description 24
- 239000007919 dispersible tablet Substances 0.000 title claims abstract description 19
- 238000002360 preparation method Methods 0.000 title description 9
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 34
- 239000000284 extract Substances 0.000 claims abstract description 30
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 25
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims abstract description 22
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- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract description 20
- 239000008213 purified water Substances 0.000 claims abstract description 12
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- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims abstract description 11
- 239000009636 Huang Qi Substances 0.000 claims abstract description 11
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims abstract description 11
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- 108010073771 Soybean Proteins Proteins 0.000 claims abstract description 11
- 229920002472 Starch Polymers 0.000 claims abstract description 11
- 239000004376 Sucralose Substances 0.000 claims abstract description 11
- 229930003427 Vitamin E Natural products 0.000 claims abstract description 11
- 239000001768 carboxy methyl cellulose Substances 0.000 claims abstract description 11
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- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 claims abstract description 11
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- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims abstract description 11
- 235000019359 magnesium stearate Nutrition 0.000 claims abstract description 11
- 239000000594 mannitol Substances 0.000 claims abstract description 11
- 235000010355 mannitol Nutrition 0.000 claims abstract description 11
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims abstract description 11
- 239000008108 microcrystalline cellulose Substances 0.000 claims abstract description 11
- 229940016286 microcrystalline cellulose Drugs 0.000 claims abstract description 11
- 239000000741 silica gel Substances 0.000 claims abstract description 11
- 229910002027 silica gel Inorganic materials 0.000 claims abstract description 11
- 239000011734 sodium Substances 0.000 claims abstract description 11
- 229910052708 sodium Inorganic materials 0.000 claims abstract description 11
- 235000019710 soybean protein Nutrition 0.000 claims abstract description 11
- 239000008107 starch Substances 0.000 claims abstract description 11
- 235000019698 starch Nutrition 0.000 claims abstract description 11
- BAQAVOSOZGMPRM-QBMZZYIRSA-N sucralose Chemical compound O[C@@H]1[C@@H](O)[C@@H](Cl)[C@@H](CO)O[C@@H]1O[C@@]1(CCl)[C@@H](O)[C@H](O)[C@@H](CCl)O1 BAQAVOSOZGMPRM-QBMZZYIRSA-N 0.000 claims abstract description 11
- 235000019408 sucralose Nutrition 0.000 claims abstract description 11
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- 235000019165 vitamin E Nutrition 0.000 claims abstract description 11
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- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims abstract description 10
- 229930003268 Vitamin C Natural products 0.000 claims abstract description 10
- 239000011718 vitamin C Substances 0.000 claims abstract description 10
- 235000019154 vitamin C Nutrition 0.000 claims abstract description 10
- 239000004615 ingredient Substances 0.000 claims abstract description 7
- 210000000952 spleen Anatomy 0.000 abstract description 15
- 210000002784 stomach Anatomy 0.000 abstract description 14
- 208000019637 Infantile Diarrhea Diseases 0.000 abstract description 4
- 230000001142 anti-diarrhea Effects 0.000 abstract description 3
- 238000005728 strengthening Methods 0.000 abstract description 3
- 238000002156 mixing Methods 0.000 description 21
- 206010012735 Diarrhoea Diseases 0.000 description 15
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 15
- 235000004879 dioscorea Nutrition 0.000 description 15
- 238000001035 drying Methods 0.000 description 14
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- 239000007788 liquid Substances 0.000 description 10
- 239000002994 raw material Substances 0.000 description 10
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- 235000005911 diet Nutrition 0.000 description 7
- 235000013305 food Nutrition 0.000 description 7
- 239000012141 concentrate Substances 0.000 description 5
- 230000037213 diet Effects 0.000 description 5
- 239000000706 filtrate Substances 0.000 description 5
- 239000000834 fixative Substances 0.000 description 5
- 238000007602 hot air drying Methods 0.000 description 5
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- PTHCMJGKKRQCBF-UHFFFAOYSA-N Cellulose, microcrystalline Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC)C(CO)O1 PTHCMJGKKRQCBF-UHFFFAOYSA-N 0.000 description 4
- 239000012535 impurity Substances 0.000 description 4
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 206010061245 Internal injury Diseases 0.000 description 2
- 230000000378 dietary effect Effects 0.000 description 2
- 201000006549 dyspepsia Diseases 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 235000015097 nutrients Nutrition 0.000 description 2
- 244000052769 pathogen Species 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- PFTAWBLQPZVEMU-DZGCQCFKSA-N (+)-catechin Chemical group C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-DZGCQCFKSA-N 0.000 description 1
- 244000241257 Cucumis melo Species 0.000 description 1
- 235000015510 Cucumis melo subsp melo Nutrition 0.000 description 1
- FJJCIZWZNKZHII-UHFFFAOYSA-N [4,6-bis(cyanoamino)-1,3,5-triazin-2-yl]cyanamide Chemical compound N#CNC1=NC(NC#N)=NC(NC#N)=N1 FJJCIZWZNKZHII-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 235000013402 health food Nutrition 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 231100000862 numbness Toxicity 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
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- 238000002560 therapeutic procedure Methods 0.000 description 1
- 229940126672 traditional medicines Drugs 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/185—Vegetable proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/20—Agglomerating; Granulating; Tabletting
- A23P10/28—Tabletting; Making food bars by compression of a dry powdered mixture
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The invention discloses a kind of Rhizoma Zingiberis Recens Fructus Jujubae Chinese yam dispersible tablet, comprise following parts by weight ingredient: Rhizoma Dioscoreae 500-700 part, Rhizoma Zingiberis Recens 70-90 part, Fructus Jujubae 20-40 part, microcrystalline Cellulose 40-60 part, Radix Astragali extract 0.12-0.32 part, Fructus Crataegi extract 0.12-0.32 part, soybean protein isolate 4-6 part, vitamin C? 1-2 part, vitamin E? 0.01-0.02 part, mannitol 100-170 part, sucralose 10-15 part, micropowder silica gel 10-50 part, carboxymethyl cellulose 3-5 part, carboxymethyl starch sodium 55-80 part, magnesium stearate 4-6 part, Purified Water q. s, 75% concentration ethanol are appropriate.The present invention has strengthening the spleen and stomach, dispersing wind and cold, and antidiarrheal is applicable to infantile diarrhea, for recovering aid.
Description
Technical field
The invention belongs to nutritional health food field, be specially a kind of Rhizoma Zingiberis Recens Fructus Jujubae Chinese yam dispersible tablet and preparation method.
Background technology
The reason that infantile diarrhea occurs, with being invaded by exogenous pathogen, internal injury diet, weakness of the spleen and stomach is common.Its major lesions at taste, because of stomach receiving food and drink digesting food, The spleen has the function to transport and transform nutrients essence of water and grain, if taste are by sick, then diet enters stomach, indigestion, precise and tiny not cloth, clear QI being mixed up with turbid QI, close dirty and under, cause into and have loose bowels.Therefore " A complete work on Pediatrics, a collection and arrangement of the chief contents from ancient pediatrics, written by Chen Fuzheng have loose bowels card control " is said: " husband have loose bowels this, invariably due to taste.Lid stomach is reservoir of food and drink, and The spleen has the function to transport and transform nutrients, make spleen stomach invigorating and, then water paddy corruption and be that QI and blood is with row Rong Wei.If intemperance of taking food, cold temperature is uncomfortable, so that taste are injured, then water be instead wet, and paddy is anti-stagnant, and the gas of elite can not defeatedization, is cause conjunction dirt and decline, and work of having loose bowels." being invaded by exogenous pathogen children's internal organs are tender and lovely, the muscle and skin being fragile, changes in temperature do not know self-regulated, are easily exopathogen invasion and attack and falling ill.Diseases caused by exogenous pathogenic factor wind, cold, summer-heat, wet, pathogenic heat all can diarrhea inducing, saying only without pathogenic dryness diarrhea inducing, cover to dislike because spleen happiness is dry to wet.Other exopathogen are then normal to be harmonious and diarrhea inducing with damp, therefore forefathers have " not becoming to rush down without wet ", the saying of " wet many one-tenth five rushes down ".Due to the factor of weather, one Winter-Spring mostly is wind and cold and wets diarrhea inducing, and autumn in summer many heat-damp in summers thermic rushes down.Children's's sudden attack of spouting diarrhea with damp and hot rush down the most common.Internal injury diet children's the spleen tending to insufficiency usually, transporting power is weak, and diet is not known from joint, if nurse inappropriate, it is improper that breast is fed, intemperance of taking food or unclean, eating cold and uncooked food excessively melon and fruit or indigestion food, all can impairing the spleen and stomach, and have loose bowels.Therefore " Plain Questions numbness opinion " is said: " eating twice as usual, the intestines and stomach is wound." diarrhea due to improper diet both can occur separately, more see more than double in other syndromes of having loose bowels.Weakness of the spleen and stomach natural endowment is not enough, and the day after tomorrow nurses inappropriate, or prolonged illness protracted course of disease, all can cause weakness of the spleen and stomach.Stomach is weak, dereliction of duty of becoming thoroughly decomposed, insufficiency of the spleen then dysfunction of the spleen in transportation and transformation, and thus water is anti-wet, and paddy is anti-stagnant, clear QI being mixed up with turbid QI, close dirty and under, form splenoasthenic diarrhea.Also there is sudden attack of spouting diarrhea excess syndrome, lose and control wrong treatment, protracted course of disease, impairing the spleen and stomach, and transfer the deficiency syndrome person of having loose bowels to by excess syndrome.As treated not in time, cause serious impact can to the healthy of child.Have a strong impact on growing up healthy and sound of child to a great extent.Although also have Chinese Traditional Medicines or the formula of a lot of infantile diarrhea at present, although treatment prescribed preparation is a lot, be all occur with the form of medicine, the dietary product being applicable to long-term edible auxiliary treatment is little.Therefore the dietary product researching and developing a kind of safe adjunct therapy is very with practical value.
Summary of the invention
For above-mentioned situation, technical problem solved by the invention is to provide a kind of strengthening the spleen and stomach, dispersing wind and cold, the Rhizoma Zingiberis Recens Fructus Jujubae Chinese yam dispersible tablet of antidiarrheal and preparation method, to solve the problem proposed in above-mentioned background technology.
For achieving the above object, the invention provides following technical scheme:
A kind of Rhizoma Zingiberis Recens Fructus Jujubae Chinese yam dispersible tablet, comprise following parts by weight ingredient: Rhizoma Dioscoreae 500-700 part, Rhizoma Zingiberis Recens 70-90 part, Fructus Jujubae 20-40 part, microcrystalline Cellulose 40-60 part, Radix Astragali extract 0.12-0.32 part, Fructus Crataegi extract 0.12-0.32 part, soybean protein isolate 4-6 part, vitamin C 1-2 part, vitamin E 0.01-0.02 part, mannitol 100-170 part, sucralose 10-15 part, micropowder silica gel 10-50 part, carboxymethyl cellulose 3-5 part, carboxymethyl starch sodium 55-80 part, magnesium stearate 4-6 part, Purified Water q. s, 75% concentration ethanol are appropriate.
As preferably, described a kind of Rhizoma Zingiberis Recens Fructus Jujubae Chinese yam dispersible tablet, comprises following parts by weight ingredient: Rhizoma Dioscoreae 600 parts, Rhizoma Zingiberis Recens 80 parts, 30 parts, Fructus Jujubae, microcrystalline Cellulose 50 parts, Radix Astragali extract 0.22 part, Fructus Crataegi extract 0.22 part, soybean protein isolate 5 parts, vitamin C 1.5 parts, vitamin E 0.015 part, 135 parts, mannitol, sucralose 12.5 parts, micropowder silica gel 30 parts, carboxymethyl cellulose 4 parts, carboxymethyl starch sodium 67.5 parts, magnesium stearate 5 parts, Purified Water q. s, 75% concentration ethanol are appropriate.
A preparation method for Rhizoma Zingiberis Recens Fructus Jujubae Chinese yam dispersible tablet, comprises the following steps:
(1) get fresh Chinese yam clear water and clean peeling, Rhizoma Dioscoreae is cut into lamellar, put into the citric acid colour-keeping liquid color retention 10-25min of 0.2-0.4%, yam slice is pulled out, yam slice after color fixative is put into the microwave drying oven that vacuum is 0.08MPa, at 50-65 DEG C of scope inner drying 30-40min, dried yam slice is first ground into 100-150 order with common grinder machine, put into super micron mill again to pulverize, be crushed to the Rhizoma Dioscoreae superfine powder that granularity is 400-500 μm, then carry out hot air drying, within the scope of 40-60 DEG C, time is 0.5-1h, for subsequent use;
(2) get raw material Rhizoma Zingiberis Recens, Fructus Jujubae is cleaned, mixing, be ground into 50-80 order, add purification water extraction 3 times, add the 3-6 times amount purified water heated and boiled 0.5-1h of raw material gross weight at every turn, cross merging filtrate after 40 eye mesh screens, concentrate, Stress control is under 0.08MPa condition, and temperature is 80 DEG C of thick liquids being concentrated into relative density 1.05-1.15 again, obtain Rhizoma Zingiberis Recens Fructus Jujubae concentrated solution, for subsequent use;
(3) be uniformly mixed by gained Rhizoma Zingiberis Recens Fructus Jujubae concentrated solution in gained Rhizoma Dioscoreae superfine powder in step (1) and step (2), blender speed is 50-75r/min, and the time is 10-15min, obtains mixture I, for subsequent use;
(4) adding ethanol to gained mixture I in step (3) makes determining alcohol reach 75%, filter after leaving standstill 8-16h, impurity is discharged, at temperature 40-60 DEG C after recovery ethanol, under vacuum 0.58-0.68MPa condition, vacuum concentration reaches 50-70% to dry substance, carry out vacuum drying again, within the scope of baking temperature 40-60 DEG C, obtain dry extract, for subsequent use;
(5) add after step (4) gained dry extract being pulverized Rhizoma Dioscoreae, Rhizoma Zingiberis Recens, Fructus Jujubae, carboxymethyl cellulose, microcrystalline Cellulose, Radix Astragali extract, Fructus Crataegi extract, soybean protein isolate, vitamin C, vitamin E, mannitol, sucralose, micropowder silica gel mixing machine mixing make granule, rotating speed is 10-15r/min, time is 6-8min, by mixing after granule 50-60 DEG C of scope inner drying to water content between 2-3%, for subsequent use;
(6) add carboxymethyl starch sodium, magnesium stearate mixing to gained granule in step (5), tabletted, obtains Rhizoma Zingiberis Recens Fructus Jujubae Chinese yam dispersible tablet.
Get fresh Chinese yam clear water in described step (1) and clean peeling, Rhizoma Dioscoreae is cut into lamellar, put into the citric acid colour-keeping liquid color retention 25min of 0.4%, yam slice is pulled out, yam slice after color fixative is put into the microwave drying oven that vacuum is 0.08MPa, at 50 DEG C of scope inner drying 30min, dried yam slice is first ground into 150 orders with common grinder machine, put into super micron mill again to pulverize, be crushed to the Rhizoma Dioscoreae superfine powder that granularity is 500 μm, carry out hot air drying again, within the scope of 40 DEG C, the time is 0.5h.
Get raw material Rhizoma Zingiberis Recens in described step (2), Fructus Jujubae is cleaned, mixing, be ground into 80 orders, add purification water extraction 3 times, add 6 times amount purified water heated and boiled 1h of raw material gross weight at every turn, excessively merging filtrate after 40 eye mesh screens, concentrate again, Stress control is under 0.08MPa condition, and temperature is 80 DEG C of thick liquids being concentrated into relative density 1.15, obtains Rhizoma Zingiberis Recens Fructus Jujubae concentrated solution.
In sum, beneficial effect of the present invention:
The present invention has strengthening the spleen and stomach, dispersing wind and cold, antidiarrheal.Be applicable to infantile diarrhea.For recovering aid.
Detailed description of the invention
Below in conjunction with the embodiment of the present invention, be clearly and completely described gained technical scheme in the embodiment of the present invention, obviously, described embodiment is only the present invention's part embodiment, instead of whole embodiments.Based on gained embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtained under creative work prerequisite, belong to the scope of protection of the invention.
Embodiment 1
A kind of Rhizoma Zingiberis Recens Fructus Jujubae Chinese yam dispersible tablet, comprises following parts by weight ingredient: Rhizoma Dioscoreae 500 parts, Rhizoma Zingiberis Recens 70 parts, 20 parts, Fructus Jujubae, microcrystalline Cellulose 40 parts, Radix Astragali extract 0.12 part, Fructus Crataegi extract 0.12 part, soybean protein isolate 4 parts, vitamin C 1 part, vitamin E 0.01 part, 100 parts, mannitol, sucralose 10 parts, micropowder silica gel 10 parts, carboxymethyl cellulose 3 parts, carboxymethyl starch sodium 55 parts, magnesium stearate 4 parts, Purified Water q. s, 75% concentration ethanol are appropriate.
A preparation method for Rhizoma Zingiberis Recens Fructus Jujubae Chinese yam dispersible tablet, comprises the following steps:
(1) get fresh Chinese yam clear water and clean peeling, Rhizoma Dioscoreae is cut into lamellar, put into the citric acid colour-keeping liquid color retention 10-25min of 0.2-0.4%, yam slice is pulled out, yam slice after color fixative is put into the microwave drying oven that vacuum is 0.08MPa, at 50-65 DEG C of scope inner drying 30-40min, dried yam slice is first ground into 100-150 order with common grinder machine, put into super micron mill again to pulverize, be crushed to the Rhizoma Dioscoreae superfine powder that granularity is 400-500 μm, then carry out hot air drying, within the scope of 40-60 DEG C, time is 0.5-1h, for subsequent use;
(2) get raw material Rhizoma Zingiberis Recens, Fructus Jujubae is cleaned, mixing, be ground into 50-80 order, add purification water extraction 3 times, add the 3-6 times amount purified water heated and boiled 0.5-1h of raw material gross weight at every turn, cross merging filtrate after 40 eye mesh screens, concentrate, Stress control is under 0.08MPa condition, and temperature is 80 DEG C of thick liquids being concentrated into relative density 1.05-1.15 again, obtain Rhizoma Zingiberis Recens Fructus Jujubae concentrated solution, for subsequent use;
(3) be uniformly mixed by gained Rhizoma Zingiberis Recens Fructus Jujubae concentrated solution in gained Rhizoma Dioscoreae superfine powder in step (1) and step (2), blender speed is 50-75r/min, and the time is 10-15min, obtains mixture I, for subsequent use;
(4) adding ethanol to gained mixture I in step (3) makes determining alcohol reach 75%, filter after leaving standstill 8-16h, impurity is discharged, at temperature 40-60 DEG C after recovery ethanol, under vacuum 0.58-0.68MPa condition, vacuum concentration reaches 50-70% to dry substance, carry out vacuum drying again, within the scope of baking temperature 40-60 DEG C, obtain dry extract, for subsequent use;
(5) add after step (4) gained dry extract being pulverized Rhizoma Dioscoreae, Rhizoma Zingiberis Recens, Fructus Jujubae, carboxymethyl cellulose, microcrystalline Cellulose, Radix Astragali extract, Fructus Crataegi extract, soybean protein isolate, vitamin C, vitamin E, mannitol, sucralose, micropowder silica gel mixing machine mixing make granule, rotating speed is 10-15r/min, time is 6-8min, by mixing after granule 50-60 DEG C of scope inner drying to water content between 2-3%, for subsequent use;
(6) add carboxymethyl starch sodium, magnesium stearate mixing to gained granule in step (5), tabletted, obtains Rhizoma Zingiberis Recens Fructus Jujubae Chinese yam dispersible tablet.
Embodiment 2
A kind of Rhizoma Zingiberis Recens Fructus Jujubae Chinese yam dispersible tablet, comprises following parts by weight ingredient: Rhizoma Dioscoreae 600 parts, Rhizoma Zingiberis Recens 80 parts, 30 parts, Fructus Jujubae, microcrystalline Cellulose 50 parts, Radix Astragali extract 0.22 part, Fructus Crataegi extract 0.22 part, soybean protein isolate 5 parts, vitamin C 1.5 parts, vitamin E 0.015 part, 135 parts, mannitol, sucralose 12.5 parts, micropowder silica gel 30 parts, carboxymethyl cellulose 4 parts, carboxymethyl starch sodium 67.5 parts, magnesium stearate 5 parts, Purified Water q. s, 75% concentration ethanol are appropriate.
A preparation method for Rhizoma Zingiberis Recens Fructus Jujubae Chinese yam dispersible tablet, comprises the following steps:
(1) get fresh Chinese yam clear water and clean peeling, Rhizoma Dioscoreae is cut into lamellar, put into the citric acid colour-keeping liquid color retention 10-25min of 0.2-0.4%, yam slice is pulled out, yam slice after color fixative is put into the microwave drying oven that vacuum is 0.08MPa, at 50-65 DEG C of scope inner drying 30-40min, dried yam slice is first ground into 100-150 order with common grinder machine, put into super micron mill again to pulverize, be crushed to the Rhizoma Dioscoreae superfine powder that granularity is 400-500 μm, then carry out hot air drying, within the scope of 40-60 DEG C, time is 0.5-1h, for subsequent use;
(2) get raw material Rhizoma Zingiberis Recens, Fructus Jujubae is cleaned, mixing, be ground into 50-80 order, add purification water extraction 3 times, add the 3-6 times amount purified water heated and boiled 0.5-1h of raw material gross weight at every turn, cross merging filtrate after 40 eye mesh screens, concentrate, Stress control is under 0.08MPa condition, and temperature is 80 DEG C of thick liquids being concentrated into relative density 1.05-1.15 again, obtain Rhizoma Zingiberis Recens Fructus Jujubae concentrated solution, for subsequent use;
(3) be uniformly mixed by gained Rhizoma Zingiberis Recens Fructus Jujubae concentrated solution in gained Rhizoma Dioscoreae superfine powder in step (1) and step (2), blender speed is 50-75r/min, and the time is 10-15min, obtains mixture I, for subsequent use;
(4) adding ethanol to gained mixture I in step (3) makes determining alcohol reach 75%, filter after leaving standstill 8-16h, impurity is discharged, at temperature 40-60 DEG C after recovery ethanol, under vacuum 0.58-0.68MPa condition, vacuum concentration reaches 50-70% to dry substance, carry out vacuum drying again, within the scope of baking temperature 40-60 DEG C, obtain dry extract, for subsequent use;
(5) add after step (4) gained dry extract being pulverized Rhizoma Dioscoreae, Rhizoma Zingiberis Recens, Fructus Jujubae, carboxymethyl cellulose, microcrystalline Cellulose, Radix Astragali extract, Fructus Crataegi extract, soybean protein isolate, vitamin C, vitamin E, mannitol, sucralose, micropowder silica gel mixing machine mixing make granule, rotating speed is 10-15r/min, time is 6-8min, by mixing after granule 50-60 DEG C of scope inner drying to water content between 2-3%, for subsequent use;
(6) add carboxymethyl starch sodium, magnesium stearate mixing to gained granule in step (5), tabletted, obtains Rhizoma Zingiberis Recens Fructus Jujubae Chinese yam dispersible tablet.
Embodiment 3
A kind of Rhizoma Zingiberis Recens Fructus Jujubae Chinese yam dispersible tablet, comprises following parts by weight ingredient: Rhizoma Dioscoreae 700 parts, Rhizoma Zingiberis Recens 90 parts, 40 parts, Fructus Jujubae, microcrystalline Cellulose 60 parts, Radix Astragali extract 0.32 part, Fructus Crataegi extract 0.32 part, soybean protein isolate 6 parts, Catergen part, vitamin E 0.02 part, 170 parts, mannitol, sucralose 15 parts, micropowder silica gel 50 parts, carboxymethyl cellulose 5 parts, carboxymethyl starch sodium 80 parts, magnesium stearate 6 parts, Purified Water q. s, 75% concentration ethanol are appropriate.
A preparation method for Rhizoma Zingiberis Recens Fructus Jujubae Chinese yam dispersible tablet, comprises the following steps:
(1) get fresh Chinese yam clear water and clean peeling, Rhizoma Dioscoreae is cut into lamellar, put into the citric acid colour-keeping liquid color retention 10-25min of 0.2-0.4%, yam slice is pulled out, yam slice after color fixative is put into the microwave drying oven that vacuum is 0.08MPa, at 50-65 DEG C of scope inner drying 30-40min, dried yam slice is first ground into 100-150 order with common grinder machine, put into super micron mill again to pulverize, be crushed to the Rhizoma Dioscoreae superfine powder that granularity is 400-500 μm, then carry out hot air drying, within the scope of 40-60 DEG C, time is 0.5-1h, for subsequent use;
(2) get raw material Rhizoma Zingiberis Recens, Fructus Jujubae is cleaned, mixing, be ground into 50-80 order, add purification water extraction 3 times, add the 3-6 times amount purified water heated and boiled 0.5-1h of raw material gross weight at every turn, cross merging filtrate after 40 eye mesh screens, concentrate, Stress control is under 0.08MPa condition, and temperature is 80 DEG C of thick liquids being concentrated into relative density 1.05-1.15 again, obtain Rhizoma Zingiberis Recens Fructus Jujubae concentrated solution, for subsequent use;
(3) be uniformly mixed by gained Rhizoma Zingiberis Recens Fructus Jujubae concentrated solution in gained Rhizoma Dioscoreae superfine powder in step (1) and step (2), blender speed is 50-75r/min, and the time is 10-15min, obtains mixture I, for subsequent use;
(4) adding ethanol to gained mixture I in step (3) makes determining alcohol reach 75%, filter after leaving standstill 8-16h, impurity is discharged, at temperature 40-60 DEG C after recovery ethanol, under vacuum 0.58-0.68MPa condition, vacuum concentration reaches 50-70% to dry substance, carry out vacuum drying again, within the scope of baking temperature 40-60 DEG C, obtain dry extract, for subsequent use;
(5) add after step (4) gained dry extract being pulverized Rhizoma Dioscoreae, Rhizoma Zingiberis Recens, Fructus Jujubae, carboxymethyl cellulose, microcrystalline Cellulose, Radix Astragali extract, Fructus Crataegi extract, soybean protein isolate, vitamin C, vitamin E, mannitol, sucralose, micropowder silica gel mixing machine mixing make granule, rotating speed is 10-15r/min, time is 6-8min, by mixing after granule 50-60 DEG C of scope inner drying to water content between 2-3%, for subsequent use;
(6) add carboxymethyl starch sodium, magnesium stearate mixing to gained granule in step (5), tabletted, obtains Rhizoma Zingiberis Recens Fructus Jujubae Chinese yam dispersible tablet.
To those skilled in the art, obviously the invention is not restricted to the details of above-mentioned one exemplary embodiment, and when not deviating from spirit of the present invention or basic feature, the present invention can be realized in other specific forms.Therefore, no matter from which point, all should embodiment be regarded as exemplary, and be nonrestrictive, scope of the present invention is limited by claims instead of above-mentioned explanation, and all changes be therefore intended in the implication of the equivalency by dropping on claim and scope are included in the present invention.
In addition, be to be understood that, although this description is described according to embodiment, but not each embodiment only comprises an independently technical scheme, this narrating mode of description is only for clarity sake, those skilled in the art should by description integrally, and in each embodiment, gained technical scheme also through appropriately combined, can form other embodiments that it will be appreciated by those skilled in the art that.
Claims (1)
1. a Rhizoma Zingiberis Recens Fructus Jujubae Chinese yam dispersible tablet, is characterized in that: be made up of following parts by weight ingredient: Rhizoma Dioscoreae 600 parts, Rhizoma Zingiberis Recens 80 parts, 30 parts, Fructus Jujubae, microcrystalline Cellulose 50 parts, Radix Astragali extract 0.22 part, Fructus Crataegi extract 0.22 part, soybean protein isolate 5 parts, vitamin C 1.5 parts, vitamin E 0.015 part, 135 parts, mannitol, sucralose 12.5 parts, micropowder silica gel 30 parts, carboxymethyl cellulose 4 parts, carboxymethyl starch sodium 67.5 parts, magnesium stearate 5 parts, Purified Water q. s, 75% concentration ethanol are appropriate.
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| CN102228186A (en) * | 2011-07-11 | 2011-11-02 | 胡可丁 | Digestible healthy rice cake |
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